ATE449769T1 - 3-(4-ää4-(4ää3-(3,3-dimethyl-1- piperidinyl)propyläoxyüphinylü-1- piperidinylcarbonylü-1-naphthalinyl)propan- oder propensäure als h1- und h3-rezeptor-antagonisten zur behandlung entzündlicher und/oder allergischer erkrankungen - Google Patents
3-(4-ää4-(4ää3-(3,3-dimethyl-1- piperidinyl)propyläoxyüphinylü-1- piperidinylcarbonylü-1-naphthalinyl)propan- oder propensäure als h1- und h3-rezeptor-antagonisten zur behandlung entzündlicher und/oder allergischer erkrankungenInfo
- Publication number
- ATE449769T1 ATE449769T1 AT06841477T AT06841477T ATE449769T1 AT E449769 T1 ATE449769 T1 AT E449769T1 AT 06841477 T AT06841477 T AT 06841477T AT 06841477 T AT06841477 T AT 06841477T AT E449769 T1 ATE449769 T1 AT E449769T1
- Authority
- AT
- Austria
- Prior art keywords
- propyläoxyüphinylü
- propeneic
- piperidinylcarbonylü
- naphthalinyl
- piperidinyl
- Prior art date
Links
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical compound CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 title 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 title 1
- 230000000172 allergic effect Effects 0.000 title 1
- 208000010668 atopic eczema Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000002757 inflammatory effect Effects 0.000 title 1
- 239000001294 propane Substances 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0525897A GB0525897D0 (en) | 2005-12-20 | 2005-12-20 | Compounds |
| GB0623217A GB0623217D0 (en) | 2006-11-21 | 2006-11-21 | Compounds |
| PCT/EP2006/069943 WO2007071691A1 (en) | 2005-12-20 | 2006-12-19 | 3- (4-{ [4-(4-{ [3-(3, 3-dimethyl-1-piperidinyl) propyl] 0xy} phenyl) -1-piperidinyl] carbonyl }-1-naphthalenyl) propanoic or propenoic acid as h1 and h3 receptor antagonists for the treatment of inflammatory and/or allergic disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE449769T1 true ATE449769T1 (de) | 2009-12-15 |
Family
ID=37845266
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06841477T ATE449769T1 (de) | 2005-12-20 | 2006-12-19 | 3-(4-ää4-(4ää3-(3,3-dimethyl-1- piperidinyl)propyläoxyüphinylü-1- piperidinylcarbonylü-1-naphthalinyl)propan- oder propensäure als h1- und h3-rezeptor-antagonisten zur behandlung entzündlicher und/oder allergischer erkrankungen |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US7989629B2 (de) |
| EP (2) | EP1963307B1 (de) |
| JP (2) | JP4445570B2 (de) |
| KR (1) | KR20080087102A (de) |
| AR (1) | AR058109A1 (de) |
| AT (1) | ATE449769T1 (de) |
| AU (1) | AU2006328512B2 (de) |
| BR (1) | BRPI0620218A2 (de) |
| CA (1) | CA2634391A1 (de) |
| CR (1) | CR10102A (de) |
| CY (1) | CY1110601T1 (de) |
| DE (1) | DE602006010737D1 (de) |
| DK (1) | DK1963307T3 (de) |
| EA (1) | EA014354B1 (de) |
| ES (1) | ES2337187T3 (de) |
| IL (1) | IL191967A0 (de) |
| MA (1) | MA30373B1 (de) |
| NO (1) | NO20082695L (de) |
| PE (1) | PE20071068A1 (de) |
| PL (1) | PL1963307T3 (de) |
| PT (1) | PT1963307E (de) |
| SI (1) | SI1963307T1 (de) |
| TW (1) | TW200730498A (de) |
| WO (1) | WO2007071691A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5791500B2 (ja) | 2008-05-23 | 2015-10-07 | パンミラ ファーマシューティカルズ，エルエルシー． | ５−リポキシゲナーゼ活性化タンパク質阻害剤 |
| US20120149731A1 (en) | 2009-06-29 | 2012-06-14 | Glaxo Group Limited | New medical use |
| JP4785963B2 (ja) | 2009-10-09 | 2011-10-05 | キヤノン株式会社 | 固体撮像装置 |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| WO2015173701A2 (en) | 2014-05-12 | 2015-11-19 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pharmaceutical compositions for treating infectious diseases |
| KR101640756B1 (ko) | 2014-10-28 | 2016-07-19 | 이종찬 | 전동 드릴 장착용 내시경 캡 |
| WO2019169082A1 (en) * | 2018-03-01 | 2019-09-06 | Ferox Therapeutics Llc | Methods of preventing and treating hypoglycemia in type 1 and type 2 diabetes patients |
| CA3173172A1 (en) | 2020-03-26 | 2021-09-30 | Christopher D. Kane | Cathepsin inhibitors for preventing or treating viral infections |
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| JPH07509694A (ja) | 1992-05-14 | 1995-10-26 | ベイラー・カレッジ・オブ・メディシン | 突然変異したステロイドホルモン受容体，その使用方法および遺伝子治療のための分子スイッチ |
| US5364791A (en) | 1992-05-14 | 1994-11-15 | Elisabetta Vegeto | Progesterone receptor having C. terminal hormone binding domain truncations |
| EP0957087B1 (de) | 1994-06-15 | 2002-12-04 | The Wellcome Foundation Limited | Zwischenprodukte verwendbar in der Herstellung von Enzym-Inhibitoren |
| MY117948A (en) | 1997-01-13 | 2004-08-30 | Glaxo Group Ltd | Nitride oxide synthase inhibitors. |
| DE19723722A1 (de) | 1997-05-30 | 1998-12-10 | Schering Ag | Nichtsteroidale Gestagene |
| WO1999016766A1 (en) | 1997-10-01 | 1999-04-08 | Kyowa Hakko Kogyo Co., Ltd. | Benzodioxole derivatives |
| US6506766B1 (en) | 1998-02-13 | 2003-01-14 | Abbott Laboratories | Glucocortiocoid-selective antinflammatory agents |
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| AU4501800A (en) | 1999-05-04 | 2000-11-17 | American Home Products Corporation | Tetracyclic progesterone receptor modulator compounds and methods |
| ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
| CO5180649A1 (es) | 1999-09-01 | 2002-07-30 | Abbott Lab | Antagonistas de los receptores de los glucocorticoides para el tratamiento de la diabetes para el tratamiento de la diabetes |
| OA11558A (en) | 1999-12-08 | 2004-06-03 | Advanced Medicine Inc | Beta 2-adrenergic receptor agonists. |
| CA2417826A1 (en) | 2000-08-05 | 2002-02-14 | Glaxo Group Limited | 17.beta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane derivative as anti-inflammatory agents |
| GB0031179D0 (en) | 2000-12-21 | 2001-01-31 | Glaxo Group Ltd | Nitric oxide synthase inhibitors |
| US6484903B2 (en) | 2001-01-09 | 2002-11-26 | Riverwood International Corporation | Carton with an improved dispensing feature in combination with a unique handle |
| GB0103630D0 (en) | 2001-02-14 | 2001-03-28 | Glaxo Group Ltd | Chemical compounds |
| JP2004526720A (ja) | 2001-03-08 | 2004-09-02 | グラクソ グループ リミテッド | βアドレナリン受容体のアゴニスト |
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| ES2438985T3 (es) | 2001-09-14 | 2014-01-21 | Glaxo Group Limited | Formulación de inhalación que comprende derivados de fenetanolamina para el tratamiento de enfermedades respiratorias |
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| EP1467982B8 (de) | 2002-01-14 | 2007-04-11 | Boehringer Ingelheim Pharmaceuticals Inc. | Glucocorticoid mimetika, verfahren zu ihrer herstellung, pharmazeutische formulierungen sie enthaltend und verwendungen davon |
| CA2473886C (en) | 2002-01-22 | 2012-08-21 | The Regents Of The University Of California | Non-steroidal ligands for the glucocorticoid receptor, compositions and uses thereof |
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| GB0220730D0 (en) | 2002-09-06 | 2002-10-16 | Glaxo Group Ltd | Medicinal compounds |
| GB0230045D0 (en) | 2002-12-23 | 2003-01-29 | Glaxo Group Ltd | Compounds |
| BR0314392A (pt) | 2002-09-16 | 2005-07-12 | Glaxo Group Ltd | Composto ou um sal do mesmo, composição farmacêutica, uso de um composto, método de tratamento e/ou profilaxia de uma doença inflamatória e/ou alérgica ou deficiência cognitiva em um mamìfero, e, combinação |
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| GB0225030D0 (en) | 2002-10-28 | 2002-12-04 | Glaxo Group Ltd | Medicinal compounds |
| GB0225540D0 (en) | 2002-11-01 | 2002-12-11 | Glaxo Group Ltd | Medicinal compounds |
| GB0225535D0 (en) | 2002-11-01 | 2002-12-11 | Glaxo Group Ltd | Medicinal compounds |
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| WO2006000398A1 (en) | 2004-06-28 | 2006-01-05 | Glaxo Group Limited | 2,3-benzoxazin derivatives as non-steroidal glucocorticoid receptor modulators |
| WO2006000401A1 (en) | 2004-06-28 | 2006-01-05 | Glaxo Group Limited | Substituted oxazines as glucocorticoid receptor modulators |
| GB0418045D0 (en) | 2004-08-12 | 2004-09-15 | Glaxo Group Ltd | Compounds |
| US7465795B2 (en) | 2005-12-20 | 2008-12-16 | Astrazeneca Ab | Compounds and uses thereof |
| CA2649029A1 (en) | 2006-04-20 | 2007-11-01 | Glaxo Group Limited | 2-substituted 4-benzylphthalazinone derivatives as histamine h1 and h3 antagonists |
-
2006
- 2006-12-18 PE PE2006001620A patent/PE20071068A1/es not_active Application Discontinuation
- 2006-12-18 TW TW095147457A patent/TW200730498A/zh unknown
- 2006-12-18 AR ARP060105590A patent/AR058109A1/es not_active Application Discontinuation
- 2006-12-19 AT AT06841477T patent/ATE449769T1/de active
- 2006-12-19 AU AU2006328512A patent/AU2006328512B2/en not_active Ceased
- 2006-12-19 PL PL06841477T patent/PL1963307T3/pl unknown
- 2006-12-19 WO PCT/EP2006/069943 patent/WO2007071691A1/en not_active Ceased
- 2006-12-19 KR KR1020087015535A patent/KR20080087102A/ko not_active Ceased
- 2006-12-19 DE DE602006010737T patent/DE602006010737D1/de active Active
- 2006-12-19 ES ES06841477T patent/ES2337187T3/es active Active
- 2006-12-19 CA CA002634391A patent/CA2634391A1/en not_active Abandoned
- 2006-12-19 EA EA200801342A patent/EA014354B1/ru not_active IP Right Cessation
- 2006-12-19 US US12/158,185 patent/US7989629B2/en not_active Expired - Fee Related
- 2006-12-19 EP EP06841477A patent/EP1963307B1/de active Active
- 2006-12-19 JP JP2008546432A patent/JP4445570B2/ja not_active Expired - Fee Related
- 2006-12-19 PT PT06841477T patent/PT1963307E/pt unknown
- 2006-12-19 BR BRPI0620218-7A patent/BRPI0620218A2/pt not_active IP Right Cessation
- 2006-12-19 EP EP09176715A patent/EP2157087A1/de not_active Withdrawn
- 2006-12-19 DK DK06841477.0T patent/DK1963307T3/da active
- 2006-12-19 SI SI200630560T patent/SI1963307T1/sl unknown
-
2008
- 2008-06-05 IL IL191967A patent/IL191967A0/en unknown
- 2008-06-11 NO NO20082695A patent/NO20082695L/no not_active Application Discontinuation
- 2008-06-11 MA MA31023A patent/MA30373B1/fr unknown
- 2008-06-20 CR CR10102A patent/CR10102A/es not_active Application Discontinuation
-
2009
- 2009-06-12 JP JP2009140796A patent/JP2009235087A/ja active Pending
-
2010
- 2010-02-19 CY CY20101100170T patent/CY1110601T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0620218A2 (pt) | 2011-11-01 |
| US7989629B2 (en) | 2011-08-02 |
| PT1963307E (pt) | 2010-03-03 |
| JP4445570B2 (ja) | 2010-04-07 |
| CA2634391A1 (en) | 2007-06-28 |
| KR20080087102A (ko) | 2008-09-30 |
| EP1963307B1 (de) | 2009-11-25 |
| EA014354B1 (ru) | 2010-10-29 |
| CR10102A (es) | 2008-09-22 |
| PL1963307T3 (pl) | 2010-05-31 |
| JP2009235087A (ja) | 2009-10-15 |
| WO2007071691A1 (en) | 2007-06-28 |
| US20080312280A1 (en) | 2008-12-18 |
| PE20071068A1 (es) | 2007-12-13 |
| MA30373B1 (fr) | 2009-05-04 |
| EP2157087A1 (de) | 2010-02-24 |
| NO20082695L (no) | 2008-09-16 |
| AU2006328512A1 (en) | 2007-06-28 |
| EP1963307A1 (de) | 2008-09-03 |
| DE602006010737D1 (de) | 2010-01-07 |
| HK1120265A1 (en) | 2009-03-27 |
| JP2009520001A (ja) | 2009-05-21 |
| TW200730498A (en) | 2007-08-16 |
| AR058109A1 (es) | 2008-01-23 |
| DK1963307T3 (da) | 2010-04-06 |
| AU2006328512B2 (en) | 2011-06-23 |
| EA200801342A1 (ru) | 2008-12-30 |
| CY1110601T1 (el) | 2015-04-29 |
| IL191967A0 (en) | 2008-12-29 |
| ES2337187T3 (es) | 2010-04-21 |
| SI1963307T1 (sl) | 2010-03-31 |
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