ATE452905T1 - Synthetische nukleinsäuremolekül- zusammensetzungen und verfahren zu ihrer herstellung - Google Patents
Synthetische nukleinsäuremolekül- zusammensetzungen und verfahren zu ihrer herstellungInfo
- Publication number
- ATE452905T1 ATE452905T1 AT01964425T AT01964425T ATE452905T1 AT E452905 T1 ATE452905 T1 AT E452905T1 AT 01964425 T AT01964425 T AT 01964425T AT 01964425 T AT01964425 T AT 01964425T AT E452905 T1 ATE452905 T1 AT E452905T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- synthetic nucleic
- production
- methods
- acid molecule
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 230000002103 transcriptional effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/645,706 US7879540B1 (en) | 2000-08-24 | 2000-08-24 | Synthetic nucleic acid molecule compositions and methods of preparation |
| PCT/US2001/026566 WO2002016944A2 (en) | 2000-08-24 | 2001-08-24 | Synthetic nucleic acid molecule compositions and methods of preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE452905T1 true ATE452905T1 (de) | 2010-01-15 |
Family
ID=24590123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01964425T ATE452905T1 (de) | 2000-08-24 | 2001-08-24 | Synthetische nukleinsäuremolekül- zusammensetzungen und verfahren zu ihrer herstellung |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US7879540B1 (de) |
| EP (1) | EP1341808B1 (de) |
| JP (3) | JP2004520807A (de) |
| AT (1) | ATE452905T1 (de) |
| AU (2) | AU8527801A (de) |
| CA (1) | CA2420328A1 (de) |
| DE (1) | DE60140898D1 (de) |
| DK (1) | DK1341808T3 (de) |
| ES (1) | ES2335268T3 (de) |
| WO (1) | WO2002016944A2 (de) |
Families Citing this family (61)
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| US6602677B1 (en) * | 1997-09-19 | 2003-08-05 | Promega Corporation | Thermostable luciferases and methods of production |
| US7879540B1 (en) | 2000-08-24 | 2011-02-01 | Promega Corporation | Synthetic nucleic acid molecule compositions and methods of preparation |
| US20030157643A1 (en) * | 2000-08-24 | 2003-08-21 | Almond Brian D | Synthetic nucleic acids from aquatic species |
| US7413874B2 (en) | 2002-12-09 | 2008-08-19 | University Of Miami | Nucleic acid encoding fluorescent proteins from aquatic species |
| AU2004236536A1 (en) * | 2003-05-06 | 2004-11-18 | National Institute Of Advanced Industrial Science And Technology | Multiple gene transcription activity determining sysyem |
| WO2005021752A1 (ja) * | 2003-08-29 | 2005-03-10 | Takara Bio Inc. | 機能的ヌクレオチド分子の検索方法 |
| JP2007508014A (ja) | 2003-10-10 | 2007-04-05 | プロメガ コーポレイション | ルシフェラーゼバイオセンサー |
| DE602005017917D1 (de) * | 2004-09-17 | 2010-01-07 | Pasteur Institut | Verfahren zur modulation der entwicklung eines durch eine nukleinsäuresequenz kodierten polypeptids |
| US7728118B2 (en) * | 2004-09-17 | 2010-06-01 | Promega Corporation | Synthetic nucleic acid molecule compositions and methods of preparation |
| WO2007030473A2 (en) * | 2005-09-06 | 2007-03-15 | Stanford University | Luciferases and methods for making and using the same |
| WO2007058140A1 (ja) | 2005-11-16 | 2007-05-24 | Toyo Boseki Kabushiki Kaisha | 細胞内発光イメージングのために最適化されたルシフェラーゼ遺伝子 |
| EP2004813B1 (de) | 2006-04-03 | 2015-06-03 | Promega Corporation | Permutierte und nichtpermutierte Luciferase-biosensoren, die zyklische Nukleotiden binden |
| CA2653256C (en) * | 2006-05-25 | 2018-08-28 | Institute For Advanced Study | Methods for identifying sequence motifs, and applications thereof |
| EP2468297B1 (de) | 2006-07-13 | 2015-09-02 | Institute For Advanced Study | Methoden zur identifizierung von Angenzien, die das AGG-Motif binden |
| EP2374875B1 (de) | 2006-10-30 | 2015-09-02 | Promega Corporation | Mutante Hydrolaseproteine mit verstärkten kinetischen Eigenschaften und funktioneller Expression |
| CN101687920B (zh) | 2007-06-29 | 2013-06-19 | 弗·哈夫曼-拉罗切有限公司 | 导致免疫球蛋白生产改善的重链突变体 |
| JP5258084B2 (ja) * | 2008-01-07 | 2013-08-07 | 株式会社ＰｒｏｂｅＸ | タンパク質間相互作用の検出方法 |
| ATE542903T1 (de) | 2008-05-19 | 2012-02-15 | Promega Corp | Luciferase-biosensoren für camp |
| JP4849698B2 (ja) | 2009-05-29 | 2012-01-11 | 国立大学法人 東京大学 | タンパク質間相互作用の高感度検出方法 |
| US9290794B2 (en) | 2010-05-11 | 2016-03-22 | Promega Corporation | Mutant protease biosensors with enhanced detection characteristics |
| WO2011143339A1 (en) | 2010-05-11 | 2011-11-17 | Promega Corporation | Mutant protease biosensors with enhanced detection characteristics |
| US9006405B2 (en) * | 2010-06-10 | 2015-04-14 | SwitchGear Genomics, Inc. | Modified renilla luciferase nucleic acids and methods of use |
| WO2012061477A1 (en) | 2010-11-02 | 2012-05-10 | Promega Corporation | Coelenterazine derivatives and methods of using same |
| CN103443121B (zh) | 2010-11-02 | 2016-04-20 | 普罗梅加公司 | 新型腔肠素底物及其使用方法 |
| WO2012174271A2 (en) * | 2011-06-16 | 2012-12-20 | The Regents Of The University Of California | Synthetic gene clusters |
| EP2776573A1 (de) | 2011-11-11 | 2014-09-17 | Promega Corporation | Mutante protease-biosensoren mit verbesserten erkennungseigenschaften |
| EP3597741A1 (de) | 2012-04-27 | 2020-01-22 | Duke University | Genetische korrektur mutierter gene |
| US10968446B2 (en) | 2012-11-01 | 2021-04-06 | Massachusetts Institute Of Technology | Directed evolution of synthetic gene cluster |
| US11072811B2 (en) | 2013-03-15 | 2021-07-27 | Promega Corporation | Substrates for covalent tethering of proteins to functional groups or solid surfaces |
| US9828582B2 (en) | 2013-03-19 | 2017-11-28 | Duke University | Compositions and methods for the induction and tuning of gene expression |
| WO2015116867A1 (en) | 2014-01-29 | 2015-08-06 | Promega Corporation | Quinone-masked probes as labeling reagents for cell uptake measurements |
| US9927430B2 (en) | 2014-01-29 | 2018-03-27 | Promega Corporation | Pro-substrates for live cell applications |
| WO2016040788A1 (en) | 2014-09-11 | 2016-03-17 | Promega Corporation | Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence |
| EP3256487A4 (de) | 2015-02-09 | 2018-07-18 | Duke University | Zusammensetzungen und verfahren zur epigenombearbeitung |
| KR102804055B1 (ko) | 2015-07-13 | 2025-05-08 | 피벗 바이오, 인크. | 식물 형질 개선을 위한 방법 및 조성물 |
| WO2017062412A1 (en) | 2015-10-05 | 2017-04-13 | Massachusetts Institute Of Technology | Nitrogen fixation using refactored nif clusters |
| EP4089175A1 (de) | 2015-10-13 | 2022-11-16 | Duke University | Genom-engineering mit typ-i-crispr-systemen in eukaryotischen zellen |
| EA201891317A3 (ru) | 2015-11-30 | 2019-04-30 | Дьюк Юниверсити | Терапевтические мишени для коррекции гена дистрофина человека с помощью редактирования генов и способы их применения |
| US20190127713A1 (en) | 2016-04-13 | 2019-05-02 | Duke University | Crispr/cas9-based repressors for silencing gene targets in vivo and methods of use |
| WO2018017754A1 (en) | 2016-07-19 | 2018-01-25 | Duke University | Therapeutic applications of cpf1-based genome editing |
| EP3510035B1 (de) | 2016-09-09 | 2021-04-07 | Promega Corporation | Doppelt geschützte pro-coelenterazin-substrate |
| MX2019008285A (es) | 2017-01-12 | 2019-11-11 | Pivot Bio Inc | Métodos y composiciones para mejorar atributos de plantas. |
| US11993778B2 (en) | 2017-10-25 | 2024-05-28 | Pivot Bio, Inc. | Methods and compositions for improving engineered microbes that fix nitrogen |
| KR20200087166A (ko) | 2017-10-25 | 2020-07-20 | 피벗 바이오, 인크. | 식물 특성 개선을 위한 질소 고정 표적화용 유전자 표적 |
| CA3022981C (en) | 2017-11-01 | 2025-05-06 | Queen's University At Kingston | HIPPO BIOLUMINOUS TRAIL BIOSENSOR |
| EP3740580A4 (de) | 2018-01-19 | 2021-10-20 | Duke University | Genom-engineering mit crispr-cas-systemen bei eukaryonten |
| CN112739668A (zh) | 2018-06-27 | 2021-04-30 | 皮沃特生物股份有限公司 | 包括重构固氮微生物的农业组合物 |
| BR112021000268A2 (pt) | 2018-07-11 | 2021-05-11 | Pivot Bio, Inc. | liberação dinâmica de nitrogênio temporalmente e espacialmente direcionada por micróbios remodelados |
| US12421519B2 (en) | 2019-01-07 | 2025-09-23 | Pivot Bio, Inc. | Plant colonization assays using natural microbial barcodes |
| EP3914734B1 (de) | 2019-01-25 | 2024-03-13 | President and Fellows of Harvard College | Zusammensetzungen und verfahren zur sequenzierung von nukleinsäuren |
| WO2020190363A1 (en) | 2019-03-19 | 2020-09-24 | Massachusetts Institute Of Technology | Control of nitrogen fixation in rhizobia that associate with cereals |
| BR112021025806A2 (pt) | 2019-06-28 | 2022-02-08 | Hoffmann La Roche | Métodos para produzir um anticorpo da subclasse igg1 humana cultivando uma célula cho e uso da remoção de sítios de splice de doador não pareados em uma parte de uma sequência de ácido nucleico de humano ou hamster |
| CN115176027A (zh) | 2019-12-12 | 2022-10-11 | 哈佛大学校长及研究员协会 | 用于光指导的生物分子条形码化的组合物和方法 |
| US20230203567A1 (en) | 2020-04-22 | 2023-06-29 | President And Fellows Of Harvard College | Isothermal methods, compositions, kits, and systems for detecting nucleic acids |
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| EP4225946A4 (de) | 2020-10-06 | 2024-10-30 | President And Fellows Of Harvard College | Verfahren, zusammensetzungen, kits und systeme für signal-on-nachweis von neutralisierungszielen |
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| EP4519290A1 (de) | 2022-05-04 | 2025-03-12 | Promega Corporation | Zirkular permutierte dehalogenasevarianten |
| KR20250044484A (ko) | 2022-06-24 | 2025-03-31 | 튠 쎄라퓨틱스, 인코포레이티드 | 표적 유전자 억제를 통해 저밀도 지단백질을 감소시키기 위한 조성물, 시스템, 및 방법 |
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| JP4311003B2 (ja) | 2002-12-02 | 2009-08-12 | アイシン精機株式会社 | 原核生物の遺伝子発現解析方法 |
| US6878531B1 (en) | 2003-11-10 | 2005-04-12 | Medical College Of Georgia Research Institute | Method for multiple site-directed mutagenesis |
| US7728118B2 (en) | 2004-09-17 | 2010-06-01 | Promega Corporation | Synthetic nucleic acid molecule compositions and methods of preparation |
-
2000
- 2000-08-24 US US09/645,706 patent/US7879540B1/en not_active Expired - Fee Related
-
2001
- 2001-08-24 AU AU8527801A patent/AU8527801A/xx active Pending
- 2001-08-24 JP JP2002521985A patent/JP2004520807A/ja active Pending
- 2001-08-24 DE DE60140898T patent/DE60140898D1/de not_active Expired - Lifetime
- 2001-08-24 EP EP01964425A patent/EP1341808B1/de not_active Expired - Lifetime
- 2001-08-24 CA CA002420328A patent/CA2420328A1/en not_active Abandoned
- 2001-08-24 AU AU2001285278A patent/AU2001285278B2/en not_active Ceased
- 2001-08-24 AT AT01964425T patent/ATE452905T1/de not_active IP Right Cessation
- 2001-08-24 WO PCT/US2001/026566 patent/WO2002016944A2/en not_active Ceased
- 2001-08-24 DK DK01964425.1T patent/DK1341808T3/da active
- 2001-08-24 ES ES01964425T patent/ES2335268T3/es not_active Expired - Lifetime
-
2005
- 2005-12-22 US US11/316,042 patent/US20060127988A1/en not_active Abandoned
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2006
- 2006-10-23 JP JP2006288147A patent/JP2007006910A/ja active Pending
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2007
- 2007-04-12 US US11/786,785 patent/US7906282B2/en not_active Expired - Fee Related
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2007006910A (ja) | 2007-01-18 |
| WO2002016944A3 (en) | 2003-06-26 |
| US20080090291A1 (en) | 2008-04-17 |
| CA2420328A1 (en) | 2002-02-28 |
| US20060127988A1 (en) | 2006-06-15 |
| EP1341808A2 (de) | 2003-09-10 |
| DE60140898D1 (de) | 2010-02-04 |
| US7879540B1 (en) | 2011-02-01 |
| EP1341808B1 (de) | 2009-12-23 |
| JP2010081942A (ja) | 2010-04-15 |
| JP2004520807A (ja) | 2004-07-15 |
| WO2002016944A2 (en) | 2002-02-28 |
| AU8527801A (en) | 2002-03-04 |
| ES2335268T3 (es) | 2010-03-24 |
| US7906282B2 (en) | 2011-03-15 |
| AU2001285278B2 (en) | 2008-05-08 |
| DK1341808T3 (da) | 2010-04-12 |
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