ATE454153T1 - 5-ht4 antagonisten zur behandlung von herzversagen - Google Patents
5-ht4 antagonisten zur behandlung von herzversagenInfo
- Publication number
- ATE454153T1 ATE454153T1 AT03725415T AT03725415T ATE454153T1 AT E454153 T1 ATE454153 T1 AT E454153T1 AT 03725415 T AT03725415 T AT 03725415T AT 03725415 T AT03725415 T AT 03725415T AT E454153 T1 ATE454153 T1 AT E454153T1
- Authority
- AT
- Austria
- Prior art keywords
- heart failure
- antagonists
- treatment
- heart
- treating
- Prior art date
Links
- 206010019280 Heart failures Diseases 0.000 title abstract 6
- 239000003523 serotonin 4 antagonist Substances 0.000 title abstract 2
- 108091005482 5-HT4 receptors Proteins 0.000 abstract 2
- 206010007559 Cardiac failure congestive Diseases 0.000 abstract 2
- 239000002464 receptor antagonist Substances 0.000 abstract 2
- 229940044551 receptor antagonist Drugs 0.000 abstract 2
- 206010007558 Cardiac failure chronic Diseases 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000019622 heart disease Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000031225 myocardial ischemia Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Electrotherapy Devices (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Treatment Of Sludge (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0211230.8A GB0211230D0 (en) | 2002-05-16 | 2002-05-16 | Treatment of heart failure |
| PCT/GB2003/002134 WO2003097065A1 (en) | 2002-05-16 | 2003-05-16 | 5-ht4 receptor antagonists for the treatment of heart failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE454153T1 true ATE454153T1 (de) | 2010-01-15 |
Family
ID=9936797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03725415T ATE454153T1 (de) | 2002-05-16 | 2003-05-16 | 5-ht4 antagonisten zur behandlung von herzversagen |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20060094715A1 (de) |
| EP (1) | EP1503764B1 (de) |
| AT (1) | ATE454153T1 (de) |
| AU (2) | AU2003227949B2 (de) |
| CA (1) | CA2485600C (de) |
| DE (1) | DE60330857D1 (de) |
| DK (1) | DK1503764T3 (de) |
| ES (1) | ES2339234T3 (de) |
| GB (1) | GB0211230D0 (de) |
| WO (1) | WO2003097065A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9890119B2 (en) | 2013-02-27 | 2018-02-13 | Shionogi & Co., Ltd. | Indole and azaindole derivative having AMPK-activating activity |
| US9956166B2 (en) | 2013-09-18 | 2018-05-01 | Sorrento Therapeutics, Inc. | Methods for administration and methods for treating cardiovascular diseases with resiniferatoxin |
| WO2015134503A1 (en) * | 2014-03-04 | 2015-09-11 | The Children's Hospital Of Philadelphia | Methods for managing care of patients predisposed to progressive mitral valve diseases |
| KR102395342B1 (ko) * | 2016-04-13 | 2022-05-10 | 보드 오브 리젠츠 오브 디 유니버시티 오브 네브라스카 | 레시니페라톡신을 사용한 투여 방법 및 심혈관 질환을 치료하는 방법 |
| KR102752382B1 (ko) * | 2019-09-20 | 2025-01-09 | 심천 사루브리스 퍼머수티칼스 컴퍼니 리미티드 | 안지오텐신 ii 수용체 길항제 대사물질 및 nep 억제제의 복합체의 심부전 치료에서의 용도 |
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| WO2007007072A1 (en) | 2005-07-07 | 2007-01-18 | Bio-Medisinsk Innovasjon As | 5-htx modulators |
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| JO2653B1 (en) | 2006-10-24 | 2012-06-17 | شركة جانسين فارماسوتيكا ان. في | Tetrahydroflavin 1-carboxylic acid substituted with pyridine or pyrazine inhibit MTB |
-
2002
- 2002-05-16 GB GBGB0211230.8A patent/GB0211230D0/en not_active Ceased
-
2003
- 2003-05-16 EP EP03725415A patent/EP1503764B1/de not_active Expired - Lifetime
- 2003-05-16 CA CA2485600A patent/CA2485600C/en not_active Expired - Fee Related
- 2003-05-16 DE DE60330857T patent/DE60330857D1/de not_active Expired - Lifetime
- 2003-05-16 AU AU2003227949A patent/AU2003227949B2/en not_active Ceased
- 2003-05-16 ES ES03725415T patent/ES2339234T3/es not_active Expired - Lifetime
- 2003-05-16 US US10/514,386 patent/US20060094715A1/en not_active Abandoned
- 2003-05-16 WO PCT/GB2003/002134 patent/WO2003097065A1/en not_active Ceased
- 2003-05-16 AT AT03725415T patent/ATE454153T1/de active
- 2003-05-16 DK DK03725415.8T patent/DK1503764T3/da active
-
2009
- 2009-01-06 AU AU2009200050A patent/AU2009200050B2/en not_active Ceased
- 2009-02-17 US US12/372,592 patent/US8829028B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009200050A1 (en) | 2009-02-05 |
| GB0211230D0 (en) | 2002-06-26 |
| WO2003097065A1 (en) | 2003-11-27 |
| DE60330857D1 (de) | 2010-02-25 |
| CA2485600C (en) | 2010-04-20 |
| EP1503764A1 (de) | 2005-02-09 |
| CA2485600A1 (en) | 2003-11-27 |
| AU2009200050B2 (en) | 2010-11-11 |
| US20090169545A1 (en) | 2009-07-02 |
| EP1503764B1 (de) | 2010-01-06 |
| US8829028B2 (en) | 2014-09-09 |
| DK1503764T3 (da) | 2010-05-10 |
| US20060094715A1 (en) | 2006-05-04 |
| ES2339234T3 (es) | 2010-05-18 |
| AU2003227949B2 (en) | 2008-12-11 |
| AU2003227949A1 (en) | 2003-12-02 |
| HK1072012A1 (en) | 2005-08-12 |
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