ATE456050T1 - Verfahren zum nachweis von bei rheumatoider arthritis gebildeten autoantikörpern - Google Patents
Verfahren zum nachweis von bei rheumatoider arthritis gebildeten autoantikörpernInfo
- Publication number
- ATE456050T1 ATE456050T1 AT06778497T AT06778497T ATE456050T1 AT E456050 T1 ATE456050 T1 AT E456050T1 AT 06778497 T AT06778497 T AT 06778497T AT 06778497 T AT06778497 T AT 06778497T AT E456050 T1 ATE456050 T1 AT E456050T1
- Authority
- AT
- Austria
- Prior art keywords
- rheumatoid arthritis
- type
- collagen
- detecting autoantibodies
- alpha1
- Prior art date
Links
- 206010039073 rheumatoid arthritis Diseases 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108010035532 Collagen Proteins 0.000 abstract 1
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010022452 Collagen Type I Proteins 0.000 abstract 1
- 102000012422 Collagen Type I Human genes 0.000 abstract 1
- 102000000503 Collagen Type II Human genes 0.000 abstract 1
- 108010041390 Collagen Type II Proteins 0.000 abstract 1
- RHGKLRLOHDJJDR-BYPYZUCNSA-N L-citrulline Chemical group NC(=O)NCCC[C@H]([NH3+])C([O-])=O RHGKLRLOHDJJDR-BYPYZUCNSA-N 0.000 abstract 1
- RHGKLRLOHDJJDR-UHFFFAOYSA-N Ndelta-carbamoyl-DL-ornithine Natural products OC(=O)C(N)CCCNC(N)=O RHGKLRLOHDJJDR-UHFFFAOYSA-N 0.000 abstract 1
- 229960002173 citrulline Drugs 0.000 abstract 1
- 235000013477 citrulline Nutrition 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 108010049937 collagen type I trimeric cross-linked peptide Proteins 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
- G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
- G01N2800/102—Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Rehabilitation Therapy (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measurement Of Radiation (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20050814A FI20050814A0 (fi) | 2005-08-11 | 2005-08-11 | Menetelmä nivelreumassa muodostuvien kollageeniautovasta-aineiden havaitsemiseksi |
| PCT/FI2006/000275 WO2007017556A1 (en) | 2005-08-11 | 2006-08-10 | Method for detecting autoantibodies formed in rheumatoid arthritis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE456050T1 true ATE456050T1 (de) | 2010-02-15 |
Family
ID=34896278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06778497T ATE456050T1 (de) | 2005-08-11 | 2006-08-10 | Verfahren zum nachweis von bei rheumatoider arthritis gebildeten autoantikörpern |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20090325884A1 (de) |
| EP (1) | EP1946109B1 (de) |
| JP (1) | JP2009505049A (de) |
| AT (1) | ATE456050T1 (de) |
| DE (1) | DE602006011934D1 (de) |
| FI (1) | FI20050814A0 (de) |
| WO (1) | WO2007017556A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0708585D0 (en) | 2007-05-03 | 2007-06-13 | Queen Mary & Westfield College | Novel antibody and use in diagnosis and therapy of arthropathies |
| EP2058663A1 (de) * | 2007-11-12 | 2009-05-13 | Euro-Diagnostica B.V. | Verfahren zur Immobilisierung eines Analyts auf einem festen Träger |
| EP3112379A1 (de) | 2008-03-21 | 2017-01-04 | Universiteit Hasselt | Biomarker für rheumatoide arthritis |
| EP2325195A1 (de) | 2009-11-23 | 2011-05-25 | Toscana Biomarkers S.r.l. | Virale citrullinierte Peptide und Verwendungen dafür |
| EP2402368A1 (de) | 2010-07-02 | 2012-01-04 | Toscana Biomarkers S.r.l. | Histoncitrullinierte Peptide und deren Verwendungen |
| US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| EP2603520A4 (de) * | 2010-08-10 | 2014-02-19 | Ecole Polytech | Erythrozytenbindende therapeutika |
| US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| DK3301107T3 (da) | 2011-04-05 | 2020-05-18 | Curara Ab | Nye peptider der bindes til typer af mhc klasse ii og deres anvendelse ved diagnosticering og behandling |
| EP2527841A1 (de) | 2011-05-25 | 2012-11-28 | Toscana Biomarkers S.r.l. | Verfahren zur Diagnose rheumatoider Arthritis |
| GB201302036D0 (en) * | 2013-02-05 | 2013-03-20 | Queen Mary & Westfield College | Diagnosis |
| US10946079B2 (en) | 2014-02-21 | 2021-03-16 | Ecole Polytechnique Federale De Lausanne | Glycotargeting therapeutics |
| US10953101B2 (en) | 2014-02-21 | 2021-03-23 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| SG11201606761RA (en) | 2014-02-21 | 2016-09-29 | Ecole Polytecnique Federale De Lausanne Epfl Epfl Tto | Glycotargeting therapeutics |
| US10046056B2 (en) | 2014-02-21 | 2018-08-14 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| WO2018232176A1 (en) | 2017-06-16 | 2018-12-20 | The University Of Chicago | Compositions and methods for inducing immune tolerance |
| CN112384204B (zh) | 2018-02-26 | 2023-03-14 | 安托瑞斯公司 | 致耐受性脂质体及其使用方法 |
| EP3790577A4 (de) | 2018-05-09 | 2022-04-27 | The University of Chicago | Zusammensetzungen und verfahren im zusammenhang mit immuntoleranz |
| CN111868073B (zh) * | 2019-05-31 | 2021-04-30 | 广州市雷德生物科技有限公司 | 一种类风湿关节炎相关的特异性多肽及其应用 |
| CN110456074B (zh) * | 2019-08-27 | 2022-06-03 | 广东菲鹏生物有限公司 | 瓜氨酸肽及其应用、类风湿关节炎的检测试剂与试剂盒 |
| EP4317172A4 (de) * | 2021-03-24 | 2025-03-05 | Sekisui Medical Co., Ltd. | Immunologisches analyseverfahren für typ-i-kollagen-c-terminales tlopeptid |
| CN113109574A (zh) * | 2021-04-15 | 2021-07-13 | 北京森美希克玛生物科技有限公司 | 检测抗突变型瓜氨酸化波形蛋白抗体的试剂盒以及检测方法 |
| CN113917135A (zh) * | 2021-10-18 | 2022-01-11 | 北京和杰创新生物医学科技有限公司 | 抗角蛋白抗体的免疫球蛋白g的检测方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3513915A1 (de) * | 1985-04-17 | 1986-10-23 | Heyl Chemisch-pharmazeutische Fabrik GmbH & Co KG, 1000 Berlin | Immunologischer testkit |
| DK104093D0 (da) * | 1993-09-17 | 1993-09-17 | Osteometer A S | Fremgangsmaade til bestemmelse af collagen-fragmenter i legemsvaesker, test-kit og midler til udoevelse af fremgangsmaaden og anvendelse af fremgangsmaaden til diagnosticering af lidelser associeret til collagen-metabolismen |
| ATE278965T1 (de) * | 1999-06-17 | 2004-10-15 | Washington Res Found | Knorpelresorptionsassays |
| JP2005511526A (ja) * | 2001-10-18 | 2005-04-28 | イレックス プロダクツ インコーポレイテッド | ジホスホネート誘導体による皮膚の治療方法 |
| NL1019540C2 (nl) * | 2001-12-11 | 2003-07-01 | Stichting Tech Wetenschapp | Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit. |
| AU2003217385B2 (en) * | 2002-02-12 | 2008-09-11 | The Regents Of The University Of California | Non-invasive method for measuring rates of biosynthesis of biological molecules by label incorporation |
| WO2004031206A2 (en) * | 2002-09-30 | 2004-04-15 | Shriners Hospitals For Children | Products for regulating the degradation of collagen and methods for indentifying same |
| JP2007524583A (ja) * | 2003-03-07 | 2007-08-30 | ロンドン・ヘルス・サイエンシズ・センター・リサーチ・インコーポレーテッド | 自己免疫異常に関わるｈｌａ−ｄｒｍｈｃクラスｉｉ分子に関するペプチド |
| ITTO20030246A1 (it) * | 2003-03-31 | 2004-10-01 | Univ Pisa | Nuovi peptidi sintetici citrullinati e loro usi. |
| SI1882946T1 (sl) * | 2003-12-23 | 2010-06-30 | Hoffmann La Roche | Postopek za ugotavljanje revmatoidnega artritisa z merjenjem anti CCP in interlevkina |
| JP2006133177A (ja) * | 2004-11-09 | 2006-05-25 | Institute Of Physical & Chemical Research | 関節リウマチの診断および治療におけるシトルリン化アンチトロンビン３の利用 |
-
2005
- 2005-08-11 FI FI20050814A patent/FI20050814A0/fi unknown
-
2006
- 2006-08-10 DE DE602006011934T patent/DE602006011934D1/de active Active
- 2006-08-10 AT AT06778497T patent/ATE456050T1/de not_active IP Right Cessation
- 2006-08-10 WO PCT/FI2006/000275 patent/WO2007017556A1/en not_active Ceased
- 2006-08-10 US US11/990,227 patent/US20090325884A1/en not_active Abandoned
- 2006-08-10 JP JP2008525592A patent/JP2009505049A/ja active Pending
- 2006-08-10 EP EP06778497A patent/EP1946109B1/de not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| EP1946109A1 (de) | 2008-07-23 |
| FI20050814A0 (fi) | 2005-08-11 |
| US20090325884A1 (en) | 2009-12-31 |
| DE602006011934D1 (de) | 2010-03-11 |
| JP2009505049A (ja) | 2009-02-05 |
| WO2007017556A1 (en) | 2007-02-15 |
| EP1946109B1 (de) | 2010-01-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |