ATE456050T1 - Verfahren zum nachweis von bei rheumatoider arthritis gebildeten autoantikörpern - Google Patents
Verfahren zum nachweis von bei rheumatoider arthritis gebildeten autoantikörpernInfo
- Publication number
- ATE456050T1 ATE456050T1 AT06778497T AT06778497T ATE456050T1 AT E456050 T1 ATE456050 T1 AT E456050T1 AT 06778497 T AT06778497 T AT 06778497T AT 06778497 T AT06778497 T AT 06778497T AT E456050 T1 ATE456050 T1 AT E456050T1
- Authority
- AT
- Austria
- Prior art keywords
- rheumatoid arthritis
- type
- collagen
- detecting autoantibodies
- alpha1
- Prior art date
Links
- 206010039073 rheumatoid arthritis Diseases 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108010035532 Collagen Proteins 0.000 abstract 1
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010022452 Collagen Type I Proteins 0.000 abstract 1
- 102000012422 Collagen Type I Human genes 0.000 abstract 1
- 102000000503 Collagen Type II Human genes 0.000 abstract 1
- 108010041390 Collagen Type II Proteins 0.000 abstract 1
- RHGKLRLOHDJJDR-BYPYZUCNSA-N L-citrulline Chemical group NC(=O)NCCC[C@H]([NH3+])C([O-])=O RHGKLRLOHDJJDR-BYPYZUCNSA-N 0.000 abstract 1
- RHGKLRLOHDJJDR-UHFFFAOYSA-N Ndelta-carbamoyl-DL-ornithine Natural products OC(=O)C(N)CCCNC(N)=O RHGKLRLOHDJJDR-UHFFFAOYSA-N 0.000 abstract 1
- 229960002173 citrulline Drugs 0.000 abstract 1
- 235000013477 citrulline Nutrition 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 108010049937 collagen type I trimeric cross-linked peptide Proteins 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
- G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
- G01N2800/102—Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rehabilitation Therapy (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Peptides Or Proteins (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measurement Of Radiation (AREA)
- Emergency Alarm Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20050814A FI20050814A0 (fi) | 2005-08-11 | 2005-08-11 | Menetelmä nivelreumassa muodostuvien kollageeniautovasta-aineiden havaitsemiseksi |
| PCT/FI2006/000275 WO2007017556A1 (en) | 2005-08-11 | 2006-08-10 | Method for detecting autoantibodies formed in rheumatoid arthritis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE456050T1 true ATE456050T1 (de) | 2010-02-15 |
Family
ID=34896278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06778497T ATE456050T1 (de) | 2005-08-11 | 2006-08-10 | Verfahren zum nachweis von bei rheumatoider arthritis gebildeten autoantikörpern |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20090325884A1 (de) |
| EP (1) | EP1946109B1 (de) |
| JP (1) | JP2009505049A (de) |
| AT (1) | ATE456050T1 (de) |
| DE (1) | DE602006011934D1 (de) |
| FI (1) | FI20050814A0 (de) |
| WO (1) | WO2007017556A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0708585D0 (en) | 2007-05-03 | 2007-06-13 | Queen Mary & Westfield College | Novel antibody and use in diagnosis and therapy of arthropathies |
| EP2058663A1 (de) * | 2007-11-12 | 2009-05-13 | Euro-Diagnostica B.V. | Verfahren zur Immobilisierung eines Analyts auf einem festen Träger |
| EP2307451B1 (de) | 2008-03-21 | 2016-05-25 | Universiteit Hasselt | Biomarker für rheumatoide arthritis |
| EP2325195A1 (de) | 2009-11-23 | 2011-05-25 | Toscana Biomarkers S.r.l. | Virale citrullinierte Peptide und Verwendungen dafür |
| EP2402368A1 (de) | 2010-07-02 | 2012-01-04 | Toscana Biomarkers S.r.l. | Histoncitrullinierte Peptide und deren Verwendungen |
| AU2011289579B2 (en) | 2010-08-10 | 2016-11-17 | Ecole Polytechnique Federale De Lausanne | Erythrocyte-binding therapeutics |
| US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| US20150218546A1 (en) | 2011-04-05 | 2015-08-06 | Lars Klareskog | Novel peptides that bind to types of mhc class ii and their use on diagnosis and treatment |
| EP2527841A1 (de) | 2011-05-25 | 2012-11-28 | Toscana Biomarkers S.r.l. | Verfahren zur Diagnose rheumatoider Arthritis |
| GB201302036D0 (en) * | 2013-02-05 | 2013-03-20 | Queen Mary & Westfield College | Diagnosis |
| US10046056B2 (en) | 2014-02-21 | 2018-08-14 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| US10946079B2 (en) | 2014-02-21 | 2021-03-16 | Ecole Polytechnique Federale De Lausanne | Glycotargeting therapeutics |
| CA2946064C (en) | 2014-02-21 | 2023-09-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Glycotargeting therapeutics |
| US10953101B2 (en) | 2014-02-21 | 2021-03-23 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| EP3638296A1 (de) | 2017-06-16 | 2020-04-22 | The University Of Chicago | Zusammensetzungen und verfahren zur herbeiführung einer immuntoleranz |
| JP2021515037A (ja) | 2018-02-26 | 2021-06-17 | アントルクス，インコーポレーテッド | 寛容原性リポソーム及びその使用方法 |
| EP3790577A4 (de) | 2018-05-09 | 2022-04-27 | The University of Chicago | Zusammensetzungen und verfahren im zusammenhang mit immuntoleranz |
| CN111868073B (zh) * | 2019-05-31 | 2021-04-30 | 广州市雷德生物科技有限公司 | 一种类风湿关节炎相关的特异性多肽及其应用 |
| CN114302743B (zh) | 2019-08-09 | 2024-05-14 | 弗劳恩霍夫应用研究促进协会 | 用于治疗关节炎的hla-dr/cii肽复合体 |
| CN114573663B (zh) * | 2019-08-27 | 2023-08-11 | 广东菲鹏生物有限公司 | 瓜氨酸肽及其应用、类风湿关节炎的检测试剂与试剂盒 |
| US20240125784A1 (en) * | 2021-03-24 | 2024-04-18 | Sekisui Medical Co., Ltd. | Immunological analysis method for type-i collagen c-terminal telopeptide |
| CN113109574A (zh) * | 2021-04-15 | 2021-07-13 | 北京森美希克玛生物科技有限公司 | 检测抗突变型瓜氨酸化波形蛋白抗体的试剂盒以及检测方法 |
| CN113917135A (zh) * | 2021-10-18 | 2022-01-11 | 北京和杰创新生物医学科技有限公司 | 抗角蛋白抗体的免疫球蛋白g的检测方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3513915A1 (de) * | 1985-04-17 | 1986-10-23 | Heyl Chemisch-pharmazeutische Fabrik GmbH & Co KG, 1000 Berlin | Immunologischer testkit |
| DK104093D0 (da) * | 1993-09-17 | 1993-09-17 | Osteometer A S | Fremgangsmaade til bestemmelse af collagen-fragmenter i legemsvaesker, test-kit og midler til udoevelse af fremgangsmaaden og anvendelse af fremgangsmaaden til diagnosticering af lidelser associeret til collagen-metabolismen |
| ES2229805T3 (es) * | 1999-06-17 | 2005-04-16 | Washington Research Foundation | Ensayos de resorcion de cartilago. |
| WO2003032909A2 (en) * | 2001-10-18 | 2003-04-24 | Ilex Products, Inc. | Methods of treating skin with diphosphonate derivatives |
| NL1019540C2 (nl) * | 2001-12-11 | 2003-07-01 | Stichting Tech Wetenschapp | Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit. |
| US7449171B2 (en) * | 2002-02-12 | 2008-11-11 | The Regents Of The University Of California | Measurement of biosynthesis and breakdown rates of biological molecules that are inaccessible or not easily accessible to direct sampling, non-invasively, by label incorporation into metabolic derivatives and catabolic products |
| CA2500669A1 (en) * | 2002-09-30 | 2004-04-15 | Shriners Hospital For Children | Products for regulating the degradation of collagen and methods for identifying same |
| AU2004216925B2 (en) * | 2003-03-07 | 2010-04-22 | London Health Sciences Centre Research Inc. | Peptides associated with HLA-DR MHC class II molecules involved in autoimmune diseases |
| ITTO20030246A1 (it) * | 2003-03-31 | 2004-10-01 | Univ Pisa | Nuovi peptidi sintetici citrullinati e loro usi. |
| WO2005064307A2 (en) * | 2003-12-23 | 2005-07-14 | Roche Diagnostics Gmbh | Method of assessing rheumatoid arthritis by measuring anti-ccp and interleukin 6 |
| JP2006133177A (ja) * | 2004-11-09 | 2006-05-25 | Institute Of Physical & Chemical Research | 関節リウマチの診断および治療におけるシトルリン化アンチトロンビン３の利用 |
-
2005
- 2005-08-11 FI FI20050814A patent/FI20050814A0/fi unknown
-
2006
- 2006-08-10 WO PCT/FI2006/000275 patent/WO2007017556A1/en not_active Ceased
- 2006-08-10 AT AT06778497T patent/ATE456050T1/de not_active IP Right Cessation
- 2006-08-10 US US11/990,227 patent/US20090325884A1/en not_active Abandoned
- 2006-08-10 DE DE602006011934T patent/DE602006011934D1/de not_active Expired - Lifetime
- 2006-08-10 JP JP2008525592A patent/JP2009505049A/ja active Pending
- 2006-08-10 EP EP06778497A patent/EP1946109B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1946109A1 (de) | 2008-07-23 |
| DE602006011934D1 (de) | 2010-03-11 |
| WO2007017556A1 (en) | 2007-02-15 |
| FI20050814A0 (fi) | 2005-08-11 |
| US20090325884A1 (en) | 2009-12-31 |
| EP1946109B1 (de) | 2010-01-20 |
| JP2009505049A (ja) | 2009-02-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |