ATE459636T1 - Stereospezifische reduktion von sapogen-3-onen - Google Patents

Stereospezifische reduktion von sapogen-3-onen

Info

Publication number
ATE459636T1
ATE459636T1 AT03720733T AT03720733T ATE459636T1 AT E459636 T1 ATE459636 T1 AT E459636T1 AT 03720733 T AT03720733 T AT 03720733T AT 03720733 T AT03720733 T AT 03720733T AT E459636 T1 ATE459636 T1 AT E459636T1
Authority
AT
Austria
Prior art keywords
derivative
steroidal
steroidal sapogenin
sapogenin
reducing
Prior art date
Application number
AT03720733T
Other languages
English (en)
Inventor
Philip Gunning
Peter Tiffin
Original Assignee
Phytopharm Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0225106A external-priority patent/GB0225106D0/en
Priority claimed from GB0301505A external-priority patent/GB0301505D0/en
Application filed by Phytopharm Plc filed Critical Phytopharm Plc
Application granted granted Critical
Publication of ATE459636T1 publication Critical patent/ATE459636T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Catalysts (AREA)
AT03720733T 2002-10-28 2003-04-28 Stereospezifische reduktion von sapogen-3-onen ATE459636T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0225106A GB0225106D0 (en) 2002-10-28 2002-10-28 Synthesis of 3 hydroxy-5 -steroids
GB0301505A GB0301505D0 (en) 2003-01-22 2003-01-22 Stereospecific synthesis of sapogenins
PCT/GB2003/001780 WO2004037845A1 (en) 2002-10-28 2003-04-28 Stereospecific reduction of sapogen-3-ones

Publications (1)

Publication Number Publication Date
ATE459636T1 true ATE459636T1 (de) 2010-03-15

Family

ID=32178884

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03720733T ATE459636T1 (de) 2002-10-28 2003-04-28 Stereospezifische reduktion von sapogen-3-onen

Country Status (17)

Country Link
US (1) US7718792B2 (de)
EP (1) EP1558627B1 (de)
JP (1) JP4607758B2 (de)
KR (1) KR101092150B1 (de)
AT (1) ATE459636T1 (de)
AU (1) AU2003224308A1 (de)
BR (1) BR0315746A (de)
CA (1) CA2503899C (de)
DE (1) DE60331572D1 (de)
ES (1) ES2342274T3 (de)
MX (1) MXPA05004494A (de)
PL (1) PL210114B1 (de)
PT (1) PT1558627E (de)
RU (1) RU2326890C2 (de)
SG (1) SG148860A1 (de)
TW (1) TWI334781B (de)
WO (1) WO2004037845A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0000228D0 (en) * 2000-01-06 2000-03-01 Phytopharm Plc Fluoro substituted sapogenins and their use
CN102727501A (zh) * 2002-03-27 2012-10-17 菲特法姆股份有限公司 皂角苷配基及其衍生物的用途
GB0409567D0 (en) 2004-04-28 2004-06-02 Phytopharm Plc Chemical compounds
US20110054156A1 (en) * 2008-04-30 2011-03-03 Institute Of Radiation Medicine, Academy Of Military Sciences, Pla Synthesis of timosaponin bii
CN106810592A (zh) * 2016-11-29 2017-06-09 杭州裕美生物科技有限公司 一种4‑烯‑3,6‑二酮甾体的合成工艺
CN115595353B (zh) * 2022-10-29 2024-08-23 西北农林科技大学 一种利用微生物转化制备薯蓣皂苷酮的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB736818A (en) 1951-12-28 1955-09-14 Glidden Co Improvements in or relating to preparation of 3-keto steroids having cis junction of rings a and b
GB763301A (en) 1953-09-05 1956-12-12 Farmaceutici Italia Process for the reduction of í¸-3-keto-steroids to 5-ª -dihydro-steroids
DE2257132C3 (de) 1972-11-18 1982-05-13 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Reduktion von 3-Ketosteroiden
CZ331094A3 (en) 1992-06-26 1995-09-13 Pfizer Steroidal glycosides and their use for treating hypercholesterolemia and atherosclerosis
JPH09500906A (ja) 1993-12-28 1997-01-28 ファイザー・インク. 血中コレステロール低下薬
MX9702175A (es) * 1994-09-20 1997-06-28 Pfizer Combinacion de un inhibidor de absorcion de colesterol y un inhibidor de sintesis de colesterol.
WO1996038466A1 (en) 1995-05-29 1996-12-05 Pfizer Inc. Steroidal glycosides
EP1066033B1 (de) 1998-03-26 2005-12-28 Phytopharm Plc Smilagenin und anzurogenin-d zur behandlung der alzheimerischen krankheit
GB9923076D0 (en) 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB0000228D0 (en) * 2000-01-06 2000-03-01 Phytopharm Plc Fluoro substituted sapogenins and their use
GB0107822D0 (en) * 2001-03-28 2001-05-23 Phytopharm Plc Sapogenin derivatives their synthesis and use methods based upon their use

Also Published As

Publication number Publication date
JP4607758B2 (ja) 2011-01-05
BR0315746A (pt) 2005-09-06
WO2004037845A1 (en) 2004-05-06
DE60331572D1 (de) 2010-04-15
ES2342274T3 (es) 2010-07-05
PL376791A1 (pl) 2006-01-09
SG148860A1 (en) 2009-01-29
CA2503899C (en) 2011-12-20
TW200406215A (en) 2004-05-01
CA2503899A1 (en) 2004-05-06
MXPA05004494A (es) 2005-07-26
PT1558627E (pt) 2010-05-06
AU2003224308A1 (en) 2004-05-13
EP1558627A1 (de) 2005-08-03
KR101092150B1 (ko) 2011-12-12
RU2326890C2 (ru) 2008-06-20
PL210114B1 (pl) 2011-12-30
US20060041119A1 (en) 2006-02-23
US7718792B2 (en) 2010-05-18
RU2005111593A (ru) 2006-05-10
JP2006507360A (ja) 2006-03-02
KR20050090379A (ko) 2005-09-13
TWI334781B (en) 2010-12-21
EP1558627B1 (de) 2010-03-03

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