ATE463493T1 - Als antipilzmittel geeignete azolderivate mit reduzierter wechselwirkung mit metabolischen zytochromen - Google Patents

Als antipilzmittel geeignete azolderivate mit reduzierter wechselwirkung mit metabolischen zytochromen

Info

Publication number
ATE463493T1
ATE463493T1 AT04790506T AT04790506T ATE463493T1 AT E463493 T1 ATE463493 T1 AT E463493T1 AT 04790506 T AT04790506 T AT 04790506T AT 04790506 T AT04790506 T AT 04790506T AT E463493 T1 ATE463493 T1 AT E463493T1
Authority
AT
Austria
Prior art keywords
cytochromes
metabolic
fungal agent
azole derivatives
derivatives suitable
Prior art date
Application number
AT04790506T
Other languages
English (en)
Inventor
Massimo Pinori
Maria Lattanzio
Daniela Modena
Paolo Mascagni
Original Assignee
Italfarmaco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco Spa filed Critical Italfarmaco Spa
Application granted granted Critical
Publication of ATE463493T1 publication Critical patent/ATE463493T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
AT04790506T 2003-10-17 2004-10-14 Als antipilzmittel geeignete azolderivate mit reduzierter wechselwirkung mit metabolischen zytochromen ATE463493T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT002020A ITMI20032020A1 (it) 2003-10-17 2003-10-17 Nuovi agenti antifungini azolici con diminuita interazione con i citocromi metabolici
PCT/EP2004/011667 WO2005040156A1 (en) 2003-10-17 2004-10-14 Azole derivative useful as antifungal agents with reduced interaction with metabolic cytochromes

Publications (1)

Publication Number Publication Date
ATE463493T1 true ATE463493T1 (de) 2010-04-15

Family

ID=34509451

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04790506T ATE463493T1 (de) 2003-10-17 2004-10-14 Als antipilzmittel geeignete azolderivate mit reduzierter wechselwirkung mit metabolischen zytochromen

Country Status (17)

Country Link
US (1) US7427620B2 (de)
EP (1) EP1673368B1 (de)
JP (1) JP4744446B2 (de)
KR (1) KR101182740B1 (de)
CN (1) CN1867565B (de)
AT (1) ATE463493T1 (de)
BR (1) BRPI0415319A (de)
CA (1) CA2542361C (de)
CY (1) CY1112166T1 (de)
DE (1) DE602004026457D1 (de)
DK (1) DK1673368T3 (de)
ES (1) ES2344703T3 (de)
IT (1) ITMI20032020A1 (de)
PL (1) PL1673368T3 (de)
PT (1) PT1673368E (de)
SI (1) SI1673368T1 (de)
WO (1) WO2005040156A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012043710A1 (ja) 2010-09-30 2012-04-05 国立大学法人 鹿児島大学 Auroraキナーゼプロモーターを含む増殖制御型ウイルスベクター

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0237693A1 (de) 1986-03-21 1987-09-23 Ambrogio Catracchia Düse zum Reinigen von Zähnen und zahnärztlichen Apparaten
DE3609596A1 (de) * 1986-03-21 1987-10-01 Hoechst Ag 2-azolylmethyl-2-aryl-1,3-dioxolane und deren salze, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung
US4788190A (en) * 1986-12-24 1988-11-29 Schering Corporation 2,4,4-tri- and 2,2,4,4-tetra substituted-1,3-dioxolane antifungal, antiallergy compounds
IL112081A (en) * 1993-12-21 2001-08-26 Schering Plough Corp Tetrahydrofuran derivatives, their preparation and antifungal pharmaceutical compositions containing them
ATE273002T1 (de) 1996-06-28 2004-08-15 Schering Corp Feste lösung eines fungizids mit erhöhter bioverfügbarkeit
ID21755A (id) 1997-02-11 1999-07-22 Janssen Pharmaceutica Nv Antijamur azol yang mengandung ester asam amino
EP0957101A1 (de) 1998-05-14 1999-11-17 Janssen Pharmaceutica N.V. Wasserlösliche Azole als Breitspektrum-antifungus
FR2807434B1 (fr) * 2000-04-05 2002-10-18 Hoechst Marion Roussel Inc Nouveaux derives de la 1,2,3,4-tetrahydroisoquinoleine, leur procede de preparation et leur application comme fongicides

Also Published As

Publication number Publication date
EP1673368B1 (de) 2010-04-07
JP2007533638A (ja) 2007-11-22
CA2542361C (en) 2012-04-24
BRPI0415319A (pt) 2006-12-05
DE602004026457D1 (de) 2010-05-20
KR20060130554A (ko) 2006-12-19
ES2344703T3 (es) 2010-09-03
CN1867565A (zh) 2006-11-22
CN1867565B (zh) 2011-06-22
EP1673368A1 (de) 2006-06-28
PT1673368E (pt) 2010-07-09
US20070129376A1 (en) 2007-06-07
WO2005040156A8 (en) 2005-06-23
KR101182740B1 (ko) 2012-09-13
CY1112166T1 (el) 2015-12-09
JP4744446B2 (ja) 2011-08-10
DK1673368T3 (da) 2010-06-07
ITMI20032020A1 (it) 2005-04-18
SI1673368T1 (sl) 2010-08-31
US7427620B2 (en) 2008-09-23
CA2542361A1 (en) 2005-05-06
PL1673368T3 (pl) 2010-09-30
WO2005040156A1 (en) 2005-05-06

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