ATE46361T1 - Verfahren zur herstellung eines proteins. - Google Patents

Verfahren zur herstellung eines proteins.

Info

Publication number
ATE46361T1
ATE46361T1 AT84301995T AT84301995T ATE46361T1 AT E46361 T1 ATE46361 T1 AT E46361T1 AT 84301995 T AT84301995 T AT 84301995T AT 84301995 T AT84301995 T AT 84301995T AT E46361 T1 ATE46361 T1 AT E46361T1
Authority
AT
Austria
Prior art keywords
protein
aqueous solution
alkaline aqueous
insoluble form
soluble native
Prior art date
Application number
AT84301995T
Other languages
English (en)
Inventor
Peter Anthony Lowe
Fiona Angela Olinda Marston
Sarojani Angal
Joyce Ann Schoemaker
Original Assignee
Celltech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27440676&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE46361(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB838308234A external-priority patent/GB8308234D0/en
Priority claimed from PCT/GB1983/000152 external-priority patent/WO1983004418A1/en
Priority claimed from GB838327345A external-priority patent/GB8327345D0/en
Application filed by Celltech Ltd filed Critical Celltech Ltd
Priority claimed from EP84301995A external-priority patent/EP0122080B1/de
Application granted granted Critical
Publication of ATE46361T1 publication Critical patent/ATE46361T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6481—Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT84301995T 1983-03-25 1984-03-23 Verfahren zur herstellung eines proteins. ATE46361T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB838308234A GB8308234D0 (en) 1983-03-25 1983-03-25 Recovery of products produced by host organisms
PCT/GB1983/000152 WO1983004418A1 (en) 1982-06-07 1983-06-07 A process for the preparation of chymosin
GB838327345A GB8327345D0 (en) 1983-06-07 1983-10-12 Production of protein
EP84301995A EP0122080B1 (de) 1983-03-25 1984-03-23 Verfahren zur Herstellung eines Proteins

Publications (1)

Publication Number Publication Date
ATE46361T1 true ATE46361T1 (de) 1989-09-15

Family

ID=27440676

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84301995T ATE46361T1 (de) 1983-03-25 1984-03-23 Verfahren zur herstellung eines proteins.

Country Status (2)

Country Link
EP (1) EP0268743B1 (de)
AT (1) ATE46361T1 (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE53517B1 (en) 1981-06-17 1988-12-07 Celltech Ltd Process for the production of a polypeptide
DE3373676D1 (en) 1982-06-07 1987-10-22 Celltech Ltd A process for the preparation of chymosin

Also Published As

Publication number Publication date
EP0268743A1 (de) 1988-06-01
EP0268743B1 (de) 1994-06-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee