ATE469647T1 - Thienoä3,2-cüpyridin-7-carbonsäure-derivate - Google Patents

Thienoä3,2-cüpyridin-7-carbonsäure-derivate

Info

Publication number
ATE469647T1
ATE469647T1 AT07787965T AT07787965T ATE469647T1 AT E469647 T1 ATE469647 T1 AT E469647T1 AT 07787965 T AT07787965 T AT 07787965T AT 07787965 T AT07787965 T AT 07787965T AT E469647 T1 ATE469647 T1 AT E469647T1
Authority
AT
Austria
Prior art keywords
thienoa3
cupyridine
acid derivatives
carbonic acid
ring
Prior art date
Application number
AT07787965T
Other languages
English (en)
Inventor
David Joseph Bartkovitz
Yi Chen
Xin-Jie Chu
Kin-Chun Thomas Luk
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE469647T1 publication Critical patent/ATE469647T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
AT07787965T 2006-08-08 2007-07-27 Thienoä3,2-cüpyridin-7-carbonsäure-derivate ATE469647T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83636006P 2006-08-08 2006-08-08
PCT/EP2007/057748 WO2008017594A1 (en) 2006-08-08 2007-07-27 Thieno[3,2-c]pyridine-7-carboxylic acid derivatives

Publications (1)

Publication Number Publication Date
ATE469647T1 true ATE469647T1 (de) 2010-06-15

Family

ID=38606469

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07787965T ATE469647T1 (de) 2006-08-08 2007-07-27 Thienoä3,2-cüpyridin-7-carbonsäure-derivate

Country Status (14)

Country Link
US (1) US7994321B2 (de)
EP (1) EP2051711B1 (de)
JP (1) JP5091237B2 (de)
KR (1) KR101101725B1 (de)
CN (1) CN101500562B (de)
AT (1) ATE469647T1 (de)
AU (1) AU2007283714B2 (de)
BR (1) BRPI0715397A2 (de)
CA (1) CA2658285C (de)
DE (1) DE602007006962D1 (de)
ES (1) ES2344324T3 (de)
IL (1) IL196418A0 (de)
MX (1) MX2009001141A (de)
WO (1) WO2008017594A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013134562A1 (en) 2012-03-09 2013-09-12 Inception 2, Inc. Triazolone compounds and uses thereof
ES2596243T3 (es) * 2012-08-24 2017-01-05 F. Hoffmann-La Roche Ag Nuevos derivados bicíclicos de piridina
MX376108B (es) 2012-12-20 2025-03-07 Tempest Therapeutics Inc Compuestos de triazolona y usos de los mismos.
AU2014315151A1 (en) 2013-09-06 2016-03-03 Inception 2, Inc. Triazolone compounds and uses thereof
CN110636846B (zh) 2017-05-17 2023-05-16 艾库斯生物科学有限公司 用于治疗癌症相关疾病的喹唑啉吡唑衍生物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7592352B2 (en) 2003-05-06 2009-09-22 Smithkline Beecham Corporation Substituted thieno and furo-pyridines
US20050026944A1 (en) 2003-07-24 2005-02-03 Patrick Betschmann Thienopyridine and furopyridine kinase inhibitors
AU2005238180A1 (en) 2004-05-04 2005-11-10 F. Hoffmann-La Roche Ag Thienopyridines as IKK inhibitors
US20050256154A1 (en) 2004-05-04 2005-11-17 Kin-Chun Luk 4-Amino-thieno[3,2-c]pyridine-7-carboxylic acid amides
BRPI0608659A2 (pt) 2005-04-06 2010-11-30 Astrazeneca Ab composto, métodos para limitar a proliferação celular, de tratamento de um ser humano ou animal sofrendo de uma doença, e de tratamento de profilaxia do cáncer, para tratar cáncer, de tratamento de infecções associadas com cáncer, e de profilaxia de infecções associadas com cáncer, composição farmacêutica, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, métodos para inibir chk1 cinase, e um pak cinase, e para limitar a tumorigênese em um ser humano ou animal, e, processo para a preparação de um composto ou um sal farmaceuticamente aceitável do mesmo

Also Published As

Publication number Publication date
AU2007283714A1 (en) 2008-02-14
MX2009001141A (es) 2009-02-10
BRPI0715397A2 (pt) 2013-11-26
DE602007006962D1 (en) 2010-07-15
US20080045562A1 (en) 2008-02-21
US7994321B2 (en) 2011-08-09
KR20090033890A (ko) 2009-04-06
WO2008017594A1 (en) 2008-02-14
CN101500562A (zh) 2009-08-05
JP2010500316A (ja) 2010-01-07
AU2007283714B2 (en) 2013-01-10
CA2658285C (en) 2016-08-23
JP5091237B2 (ja) 2012-12-05
IL196418A0 (en) 2009-09-22
CA2658285A1 (en) 2008-02-14
ES2344324T3 (es) 2010-08-24
EP2051711A1 (de) 2009-04-29
CN101500562B (zh) 2012-01-25
KR101101725B1 (ko) 2012-01-05
EP2051711B1 (de) 2010-06-02

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