ATE474060T1 - Verfahren zur herstellung von polymyxin b unter verwendung von (paeni)bacillus polymyxa - Google Patents

Verfahren zur herstellung von polymyxin b unter verwendung von (paeni)bacillus polymyxa

Info

Publication number
ATE474060T1
ATE474060T1 AT07748763T AT07748763T ATE474060T1 AT E474060 T1 ATE474060 T1 AT E474060T1 AT 07748763 T AT07748763 T AT 07748763T AT 07748763 T AT07748763 T AT 07748763T AT E474060 T1 ATE474060 T1 AT E474060T1
Authority
AT
Austria
Prior art keywords
bacillus polymyxa
paeni
polymyxin
producing polymyxin
producing
Prior art date
Application number
AT07748763T
Other languages
English (en)
Inventor
Ivan Varga
Katarina Vreblova
Ludmila Kovacov
Original Assignee
Biotika As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotika As filed Critical Biotika As
Application granted granted Critical
Publication of ATE474060T1 publication Critical patent/ATE474060T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT07748763T 2006-06-15 2007-05-21 Verfahren zur herstellung von polymyxin b unter verwendung von (paeni)bacillus polymyxa ATE474060T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SK90-2006A SK287293B6 (sk) 2006-06-15 2006-06-15 Spôsob fermentácie polymyxínu B pomocou produkčného mikroorganizmu Bacillus polymyxa
PCT/SK2007/050011 WO2007145602A1 (en) 2006-06-15 2007-05-21 Process for the preparation of polymyxin b employing ( paeni ) bacillus polymyxa

Publications (1)

Publication Number Publication Date
ATE474060T1 true ATE474060T1 (de) 2010-07-15

Family

ID=38328655

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07748763T ATE474060T1 (de) 2006-06-15 2007-05-21 Verfahren zur herstellung von polymyxin b unter verwendung von (paeni)bacillus polymyxa

Country Status (8)

Country Link
US (1) US8119371B2 (de)
EP (1) EP2027280B1 (de)
AT (1) ATE474060T1 (de)
ES (1) ES2349188T3 (de)
PL (1) PL2027280T3 (de)
SI (1) SI2027280T1 (de)
SK (1) SK287293B6 (de)
WO (1) WO2007145602A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101171862B1 (ko) 2009-09-18 2012-08-31 한국생명공학연구원 재조합 바실러스 균을 이용한 폴리믹신 생산방법
WO2010058427A2 (en) 2008-11-24 2010-05-27 Reliance Life Sciences Pvt. Ltd. Process for production and purification of polymyxin b sulfate
CN103509839B (zh) * 2013-10-12 2015-02-25 河北圣雪大成制药有限责任公司 一种降低多粘菌素e发酵液中氨氮含量的方法
CN103540633B (zh) * 2013-10-24 2016-01-20 河北圣雪大成制药有限责任公司 一种发酵法生产多粘菌素b的方法
CN104774892B (zh) * 2014-01-13 2018-11-30 上海医药工业研究院 一种用于生产多黏菌素b的发酵培养基及其制备方法和用途
CN110551786B (zh) * 2019-09-12 2021-12-07 浙江海正药业股份有限公司 一种提高a40926 b0产量的发酵培养基及其方法
CN113755548A (zh) * 2021-09-02 2021-12-07 河北圣雪大成制药有限责任公司 一种提高多粘菌素b发酵水平的方法
CN115181774B (zh) * 2022-08-04 2025-11-18 河北圣雪大成制药有限责任公司 一种提高多粘菌素b有效组分含量的发酵液制备方法

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Also Published As

Publication number Publication date
US8119371B2 (en) 2012-02-21
US20090197305A1 (en) 2009-08-06
SK287293B6 (sk) 2010-05-07
WO2007145602A1 (en) 2007-12-21
EP2027280B1 (de) 2010-07-14
EP2027280A1 (de) 2009-02-25
SK902006A3 (sk) 2008-02-05
PL2027280T3 (pl) 2010-12-31
ES2349188T3 (es) 2010-12-28
SI2027280T1 (sl) 2010-12-31

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