ATE483476T1 - Micellen-zubereitung mit schwer wasserlöslichem anti-krebsmittel und neuem blockcopolymer - Google Patents

Micellen-zubereitung mit schwer wasserlöslichem anti-krebsmittel und neuem blockcopolymer

Info

Publication number
ATE483476T1
ATE483476T1 AT04721673T AT04721673T ATE483476T1 AT E483476 T1 ATE483476 T1 AT E483476T1 AT 04721673 T AT04721673 T AT 04721673T AT 04721673 T AT04721673 T AT 04721673T AT E483476 T1 ATE483476 T1 AT E483476T1
Authority
AT
Austria
Prior art keywords
block copolymer
integer
water soluble
cancer agent
new block
Prior art date
Application number
AT04721673T
Other languages
English (en)
Inventor
Kazuhisa Shimizu
Toshitaka Murata
Katsuhiko Sagawa
Original Assignee
Nippon Kayaku Kk
Nanocarrier Kabushiki Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Kayaku Kk, Nanocarrier Kabushiki Kaisha filed Critical Nippon Kayaku Kk
Application granted granted Critical
Publication of ATE483476T1 publication Critical patent/ATE483476T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyamides (AREA)
  • Peptides Or Proteins (AREA)
AT04721673T 2003-03-20 2004-03-18 Micellen-zubereitung mit schwer wasserlöslichem anti-krebsmittel und neuem blockcopolymer ATE483476T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003077607 2003-03-20
PCT/JP2004/003647 WO2004082718A1 (ja) 2003-03-20 2004-03-18 難水溶性抗癌剤と新規ブロック共重合体を含むミセル調製物

Publications (1)

Publication Number Publication Date
ATE483476T1 true ATE483476T1 (de) 2010-10-15

Family

ID=33027953

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04721673T ATE483476T1 (de) 2003-03-20 2004-03-18 Micellen-zubereitung mit schwer wasserlöslichem anti-krebsmittel und neuem blockcopolymer

Country Status (14)

Country Link
US (3) US20060099265A1 (de)
EP (1) EP1604687B1 (de)
JP (1) JP4757633B2 (de)
KR (1) KR101064901B1 (de)
CN (1) CN1761485B (de)
AT (1) ATE483476T1 (de)
AU (1) AU2004222439B2 (de)
CA (1) CA2518964C (de)
DE (1) DE602004029449D1 (de)
DK (1) DK1604687T3 (de)
ES (1) ES2351338T3 (de)
PL (1) PL1604687T3 (de)
RU (1) RU2324701C2 (de)
WO (1) WO2004082718A1 (de)

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US8323669B2 (en) 2006-03-28 2012-12-04 Nippon Kayaku Kabushiki Kaisha Polymer conjugate of taxane
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JP5548365B2 (ja) 2006-11-08 2014-07-16 日本化薬株式会社 核酸系代謝拮抗剤の高分子誘導体
JP5349318B2 (ja) 2007-09-28 2013-11-20 日本化薬株式会社 ステロイド類の高分子結合体
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JP5366940B2 (ja) 2008-05-08 2013-12-11 日本化薬株式会社 葉酸若しくは葉酸誘導体の高分子結合体
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JP5037684B2 (ja) 2008-05-23 2012-10-03 ナノキャリア株式会社 ドセタキセル高分子誘導体、並びにその製造方法及びその用途
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JP5544357B2 (ja) 2009-05-15 2014-07-09 日本化薬株式会社 水酸基を有する生理活性物質の高分子結合体
PL2474306T3 (pl) * 2009-08-31 2017-06-30 Nanocarrier Co., Ltd. Kompozycja w postaci cząstek stałych i zawierająca ją kompozycja lecznicza
KR20140024833A (ko) 2010-11-17 2014-03-03 니폰 가야꾸 가부시끼가이샤 신규한 시티딘계 대사길항제의 고분자 유도체
CN103874722B (zh) 2011-09-11 2016-06-29 日本化药株式会社 嵌段共聚物的制造方法
EP3400945A4 (de) 2016-01-08 2019-09-11 Nippon Kayaku Kabushiki Kaisha Polymerderivat von macrolid-immunosuppressiva
JP6924191B2 (ja) 2016-07-30 2021-08-25 日本化薬株式会社 新規な高分子誘導体、及びそれらを用いた新規な高分子誘導体イメージングプローブ
EP3495406A4 (de) 2016-08-02 2020-04-01 Nippon Kayaku Kabushiki Kaisha Auf einen wirkstoff gerichtetes polymerderivat, zusammensetzung mit diesem polymerderivat und verwendung dieses polymerderivats sowie diese zusammensetzung
WO2022008527A1 (en) 2020-07-06 2022-01-13 Rheinisch-Westfälische Technische Hochschule (Rwth) Aachen Polymeric micelles comprising glucuronide-prodrugs

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JP5544357B2 (ja) * 2009-05-15 2014-07-09 日本化薬株式会社 水酸基を有する生理活性物質の高分子結合体

Also Published As

Publication number Publication date
CA2518964A1 (en) 2004-09-30
EP1604687B1 (de) 2010-10-06
EP1604687A1 (de) 2005-12-14
EP1604687A4 (de) 2009-03-18
US7820759B2 (en) 2010-10-26
US20090156742A1 (en) 2009-06-18
CN1761485B (zh) 2010-04-28
US20060099265A1 (en) 2006-05-11
RU2005132309A (ru) 2006-04-10
PL1604687T3 (pl) 2011-04-29
CA2518964C (en) 2011-09-13
WO2004082718A1 (ja) 2004-09-30
AU2004222439B2 (en) 2008-08-21
KR101064901B1 (ko) 2011-09-16
DE602004029449D1 (de) 2010-11-18
JP4757633B2 (ja) 2011-08-24
JPWO2004082718A1 (ja) 2006-06-22
ES2351338T3 (es) 2011-02-03
US20140142167A1 (en) 2014-05-22
CN1761485A (zh) 2006-04-19
AU2004222439A1 (en) 2004-09-30
DK1604687T3 (da) 2010-11-15
RU2324701C2 (ru) 2008-05-20
KR20050107800A (ko) 2005-11-15

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