ATE483792T1 - Verfahren zur fermentativen herstellung von l- glutaminsäure - Google Patents
Verfahren zur fermentativen herstellung von l- glutaminsäureInfo
- Publication number
- ATE483792T1 ATE483792T1 AT99125302T AT99125302T ATE483792T1 AT E483792 T1 ATE483792 T1 AT E483792T1 AT 99125302 T AT99125302 T AT 99125302T AT 99125302 T AT99125302 T AT 99125302T AT E483792 T1 ATE483792 T1 AT E483792T1
- Authority
- AT
- Austria
- Prior art keywords
- glutamic acid
- fermentative production
- glutamine acid
- pyruvate dehydrogenase
- producing ability
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 238000012262 fermentative production Methods 0.000 title 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 10
- 229960002989 glutamic acid Drugs 0.000 abstract 5
- 101710088194 Dehydrogenase Proteins 0.000 abstract 2
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 abstract 2
- 230000003834 intracellular effect Effects 0.000 abstract 2
- 229930003451 Vitamin B1 Natural products 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 241000186254 coryneform bacterium Species 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 229960003495 thiamine Drugs 0.000 abstract 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 abstract 1
- 239000011691 vitamin B1 Substances 0.000 abstract 1
- 235000010374 vitamin B1 Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N3/00—Spore forming or isolating processes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/14—Glutamic acid; Glutamine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP36061998 | 1998-12-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE483792T1 true ATE483792T1 (de) | 2010-10-15 |
Family
ID=18470193
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99125302T ATE483792T1 (de) | 1998-12-18 | 1999-12-17 | Verfahren zur fermentativen herstellung von l- glutaminsäure |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1010755B1 (de) |
| CN (1) | CN100358999C (de) |
| AT (1) | ATE483792T1 (de) |
| BR (1) | BR9906279A (de) |
| DE (1) | DE69942821D1 (de) |
| ID (1) | ID24576A (de) |
| MY (1) | MY137515A (de) |
| PE (1) | PE20001375A1 (de) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19956131A1 (de) | 1999-11-23 | 2001-05-31 | Degussa | Neue für das pfk-Gen codierende Nukleotidsequenzen |
| WO2003076635A1 (en) * | 2002-03-13 | 2003-09-18 | Degussa Ag | Process for the preparation of l-amino acids using strains of the family enterobacteriaceae |
| BRPI0519410B1 (pt) | 2004-12-28 | 2020-12-22 | Ajinomoto Co., Inc | método para produzir ácido l-glutâmico |
| JP2009118740A (ja) | 2006-03-03 | 2009-06-04 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| JP2010041920A (ja) | 2006-12-19 | 2010-02-25 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| JP2010130899A (ja) | 2007-03-14 | 2010-06-17 | Ajinomoto Co Inc | Ｌ−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法 |
| EP2192170B1 (de) | 2007-09-04 | 2017-02-15 | Ajinomoto Co., Inc. | Aminosäureproduzierender mikroorganismus und verfahren zur aminosäureproduktion |
| KR20100120663A (ko) | 2008-01-23 | 2010-11-16 | 아지노모토 가부시키가이샤 | Ｌ-아미노산의 제조법 |
| PE20110369A1 (es) | 2008-09-08 | 2011-06-24 | Ajinomoto Kk | Un microorganismo que produce l-aminoacido y un metodo para producir un l-aminoacido |
| JPWO2011013707A1 (ja) | 2009-07-29 | 2013-01-10 | 味の素株式会社 | Ｌ−アミノ酸の製造法 |
| JP2012223092A (ja) | 2009-08-28 | 2012-11-15 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| JP2013013329A (ja) | 2009-11-06 | 2013-01-24 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| JP2013074795A (ja) | 2010-02-08 | 2013-04-25 | Ajinomoto Co Inc | 変異型ｒｐｓＡ遺伝子及びＬ−アミノ酸の製造法 |
| JP2014036576A (ja) | 2010-12-10 | 2014-02-27 | Ajinomoto Co Inc | Ｌ−アミノ酸の製造法 |
| BR112013027845A2 (pt) | 2011-05-18 | 2017-01-03 | Ajinomoto Kk | Imunoestimulante, ração, método para produzir um imunoestimulante, e, método para imunoestimulação |
| PH12014501063A1 (en) | 2011-11-11 | 2014-06-30 | Ajinomoto Kk | A method for producing a target substance by fermentation |
| CN105008532B (zh) | 2013-05-13 | 2017-07-21 | 味之素株式会社 | L‑氨基酸的制造方法 |
| JP2016165225A (ja) | 2013-07-09 | 2016-09-15 | 味の素株式会社 | 有用物質の製造方法 |
| JP2016192903A (ja) | 2013-09-17 | 2016-11-17 | 味の素株式会社 | 海藻由来バイオマスからのｌ−アミノ酸の製造方法 |
| JP6459962B2 (ja) | 2013-10-21 | 2019-01-30 | 味の素株式会社 | Ｌ−アミノ酸の製造法 |
| JP6519476B2 (ja) | 2013-10-23 | 2019-05-29 | 味の素株式会社 | 目的物質の製造法 |
| KR102265924B1 (ko) | 2014-10-31 | 2021-06-15 | 삼성바이오에피스 주식회사 | Pdk 불활성화에 의한 폴리펩타이드의 생산 |
| KR101776375B1 (ko) * | 2015-03-18 | 2017-09-08 | 씨제이제일제당 (주) | 피루브산 디하이드로게나아제 변이체, 이를 포함하는 미생물 및 이를 이용한 l-아미노산 생산 방법 |
| JP6623690B2 (ja) | 2015-10-30 | 2019-12-25 | 味の素株式会社 | グルタミン酸系ｌ−アミノ酸の製造法 |
| JP7066977B2 (ja) | 2017-04-03 | 2022-05-16 | 味の素株式会社 | Ｌ－アミノ酸の製造法 |
| CN107974473B (zh) * | 2017-12-15 | 2020-06-19 | 内蒙古伊品生物科技有限公司 | 谷氨酸的发酵生产及后处理 |
| WO2020071538A1 (en) | 2018-10-05 | 2020-04-09 | Ajinomoto Co., Inc. | Method for producing target substance by bacterial fermentation |
| WO2020138178A1 (en) | 2018-12-27 | 2020-07-02 | Ajinomoto Co., Inc. | Method for producing basic l-amino acids or salts thereof by fermentation of an enterobacteriaceae bacterium |
| JP7491314B2 (ja) | 2019-02-22 | 2024-05-28 | 味の素株式会社 | ｙｄｉＪ遺伝子を過剰発現する腸内細菌科に属する細菌を用いたＬ－アミノ酸の製造方法 |
| JP7524909B2 (ja) | 2019-04-05 | 2024-07-30 | 味の素株式会社 | Ｌ－アミノ酸の製造方法 |
| WO2021060337A1 (en) | 2019-09-25 | 2021-04-01 | Ajinomoto Co., Inc. | Method for producing 2-methyl-butyric acid by bacterial fermentation |
| JP7655312B2 (ja) | 2019-09-25 | 2025-04-02 | 味の素株式会社 | 細菌の発酵によるｌ－アミノ酸の製造方法 |
| WO2022092018A1 (ja) | 2020-10-28 | 2022-05-05 | 味の素株式会社 | Ｌ－アミノ酸の製造法 |
| US20240117393A1 (en) | 2022-09-30 | 2024-04-11 | Ajinomoto Co., Inc. | Method for producing l-amino acid |
| JP7716166B1 (ja) | 2023-12-28 | 2025-07-31 | 味の素株式会社 | Ｌ－グルタミン酸生産菌およびｌ－グルタミン酸の製造方法 |
| JP7716823B1 (ja) | 2023-12-28 | 2025-08-01 | 味の素株式会社 | Ｌ－グルタミン酸生産菌およびｌ－グルタミン酸の製造方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2520895B2 (ja) * | 1987-03-04 | 1996-07-31 | 旭化成工業株式会社 | Ｌ―グルタミン酸の製造方法 |
| ES2191710T3 (es) | 1994-08-19 | 2003-09-16 | Ajinomoto Kk | Procedimiento para producir l-lisina y acido l-glutamico por fermentacion. |
-
1999
- 1999-12-17 EP EP99125302A patent/EP1010755B1/de not_active Expired - Lifetime
- 1999-12-17 DE DE69942821T patent/DE69942821D1/de not_active Expired - Lifetime
- 1999-12-17 BR BR9906279-8A patent/BR9906279A/pt not_active Application Discontinuation
- 1999-12-17 MY MYPI99005539A patent/MY137515A/en unknown
- 1999-12-17 AT AT99125302T patent/ATE483792T1/de not_active IP Right Cessation
- 1999-12-17 PE PE1999001285A patent/PE20001375A1/es not_active Application Discontinuation
- 1999-12-18 CN CNB99122969XA patent/CN100358999C/zh not_active Expired - Fee Related
- 1999-12-20 ID IDP991158A patent/ID24576A/id unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1270226A (zh) | 2000-10-18 |
| DE69942821D1 (de) | 2010-11-18 |
| MY137515A (en) | 2009-02-27 |
| EP1010755A1 (de) | 2000-06-21 |
| ID24576A (id) | 2000-07-27 |
| BR9906279A (pt) | 2001-04-24 |
| CN100358999C (zh) | 2008-01-02 |
| PE20001375A1 (es) | 2000-12-14 |
| EP1010755B1 (de) | 2010-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |