ATE487501T1 - Hämostatische zusammensetzungen und vorrichtungen - Google Patents

Hämostatische zusammensetzungen und vorrichtungen

Info

Publication number
ATE487501T1
ATE487501T1 AT05250487T AT05250487T ATE487501T1 AT E487501 T1 ATE487501 T1 AT E487501T1 AT 05250487 T AT05250487 T AT 05250487T AT 05250487 T AT05250487 T AT 05250487T AT E487501 T1 ATE487501 T1 AT E487501T1
Authority
AT
Austria
Prior art keywords
liquid
devices
weight
hemostatic compositions
compositions
Prior art date
Application number
AT05250487T
Other languages
English (en)
Inventor
Sanyog M Pendharkar
Anne J Gorman
Thomas L Craven
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Application granted granted Critical
Publication of ATE487501T1 publication Critical patent/ATE487501T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0042—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/009—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
    • A61L2300/208—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Surgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Surgical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT05250487T 2004-01-30 2005-01-31 Hämostatische zusammensetzungen und vorrichtungen ATE487501T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/768,912 US7109163B2 (en) 2004-01-30 2004-01-30 Hemostatic compositions and devices

Publications (1)

Publication Number Publication Date
ATE487501T1 true ATE487501T1 (de) 2010-11-15

Family

ID=34654376

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05250487T ATE487501T1 (de) 2004-01-30 2005-01-31 Hämostatische zusammensetzungen und vorrichtungen

Country Status (8)

Country Link
US (1) US7109163B2 (de)
EP (1) EP1559438B1 (de)
JP (2) JP5178992B2 (de)
AT (1) ATE487501T1 (de)
CA (1) CA2495048C (de)
DE (1) DE602005024633D1 (de)
DK (1) DK1559438T3 (de)
ES (1) ES2352088T3 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7923431B2 (en) * 2001-12-21 2011-04-12 Ferrosan Medical Devices A/S Haemostatic kit, a method of preparing a haemostatic agent and a method of promoting haemostatis
BR0317237A (pt) 2002-12-11 2005-11-01 Ferrosan As Dispositivo para amostragem ou coleta, kit, usos de um dispositivo e de um kit, e, métodos para diminuir a quantidade de um marcador em uma área de amostra, para amostrar de modo qualitativo ou quantitativo uma área quanto ao teor de um marcador e para cultivar microorganismos ou células de mamìferos coletados
US8440225B2 (en) * 2003-08-07 2013-05-14 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
US20060019868A1 (en) * 2004-01-30 2006-01-26 Pendharkar Sanyog M Hemostatic compositions and devices
US7927626B2 (en) * 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
ATE475434T1 (de) 2004-01-30 2010-08-15 Ferrosan As Hämostatische sprays und zusammensetzungen
US7109163B2 (en) * 2004-01-30 2006-09-19 Ethicon, Inc. Hemostatic compositions and devices
RU2369408C2 (ru) 2004-07-09 2009-10-10 Ферросан А/С Гемостатическая композиция, включающая гиалуроновую кислоту
US8133484B2 (en) 2006-12-15 2012-03-13 Lifebond Ltd Hemostatic materials and dressing
MX2009006369A (es) 2006-12-15 2010-02-24 Lifebond Ltd Apositos y selladores hemostaticos de gelatina-transglutaminasa.
WO2009109194A2 (en) 2008-02-29 2009-09-11 Ferrosan A/S Device for promotion of hemostasis and/or wound healing
WO2009123903A1 (en) 2008-04-03 2009-10-08 Zymogenetics, Inc. Hemostatic microspheres
US9213035B2 (en) 2008-05-22 2015-12-15 Ethicon, Inc. Protein assay
CN104031393B (zh) 2008-06-18 2017-08-01 生命连结有限公司 改进的交联组合物
JP5796860B2 (ja) 2009-12-22 2015-10-21 ライフボンド リミテッドＬｉｆｅｂｏｎｄ Ｌｔｄ 架橋マトリックスの特性を調節するための酵素的架橋剤の改変
MX352875B (es) * 2010-06-01 2017-12-13 Baxter Healthcare Sa Proceso para elaborar composiciones hemostaticas secas y estables.
EP2600910B1 (de) 2010-08-05 2016-01-20 Lifebond Ltd Wundverbände mit einer trockenzusammung und haftstoffe
JP6065187B2 (ja) * 2011-06-20 2017-01-25 レキット アンド コールマン （オーヴァーシーズ） リミテッド 起泡性局所抗菌洗浄組成物
JP6241624B2 (ja) 2012-03-06 2017-12-06 フェロサン メディカル デバイシーズ エイ／エス 止血ペーストを収容する加圧容器
CN104349797B (zh) 2012-06-12 2017-10-27 弗罗桑医疗设备公司 干止血组合物
US9040093B2 (en) 2013-03-13 2015-05-26 Orthovita, Inc. Bone graft materials containing calcium phosphate and chitosan
EP3010419B1 (de) 2013-06-21 2020-05-20 Ferrosan Medical Devices A/S Vakuumerweiterte trockenzusammensetzung und spritze zum zurückhalten davon
EP3079731B1 (de) * 2013-12-11 2018-08-08 Ferrosan Medical Devices A/S Trockenzusammensetzung mit extrusionsverstärker
JP6726852B2 (ja) 2014-10-13 2020-07-22 フェッローサン メディカル ディバイス エー／エス 止血および創傷治癒に使用するための乾燥組成物
RU2705905C2 (ru) 2014-12-24 2019-11-12 Ферросан Медикал Дивайсиз А/С Шприц для удерживания и смешивания первого и второго веществ
AU2016290433B2 (en) 2015-07-03 2018-05-24 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
EP3538071B1 (de) 2016-11-10 2022-09-14 Medisca Pharmaceutique Inc. Pharmazeutische compoundierungsverfahren und -systeme
US11007299B2 (en) 2017-11-08 2021-05-18 Ethicon, Inc. Hemostatic paste having surface enriched with hemostasis-promoting agents and devices for delivery
CN112368028A (zh) * 2018-05-09 2021-02-12 弗罗桑医疗设备公司 用于制备止血组合物的方法
US11998654B2 (en) 2018-07-12 2024-06-04 Bard Shannon Limited Securing implants and medical devices
IL262716A (en) * 2018-11-01 2018-11-29 Omrix Biopharmaceuticals Ltd Oxidized cellulose preparations
JP7389418B2 (ja) * 2019-02-18 2023-11-30 青葉化成株式会社 止血剤
US12285540B2 (en) 2020-07-21 2025-04-29 Ethicon, Inc. Hemostatic composite aggregate materials having surface enriched with hemostatis-promoting agents
CN113144277B (zh) * 2021-04-13 2022-06-14 武汉理工大学 一种可注射流体明胶及其制备方法和应用
WO2022217492A1 (en) * 2021-04-14 2022-10-20 Guangzhou Bioseal Biotech Co., Ltd. Flowable hemostatic paste
CN115154646B (zh) * 2022-06-20 2023-12-01 国科温州研究院(温州生物材料与工程研究所) 一种可降解止血微球及制备方法与应用
JP2026513343A (ja) * 2023-04-04 2026-04-23 コウシュウ・バイオシール・バイオテック・カンパニー・リミテッド 組織における漏出を封止するための止血シーラント粉末

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2507244A (en) * 1947-04-14 1950-05-09 Upjohn Co Surgical gelatin dusting powder and process for preparing same
JPS6144825A (ja) * 1984-08-09 1986-03-04 Unitika Ltd 止血剤
ATE43716T1 (de) 1986-03-19 1989-06-15 Rollei Fototechnic Gmbh Verfahren zur photogrammetrischen erfassung eines objektes mit hilfe zumindest eines optoelektrischen festkoerper-flaechensensors.
JPS62228009A (ja) * 1986-03-29 1987-10-06 Nitto Electric Ind Co Ltd 外用部材
DE3706484A1 (de) * 1987-02-27 1988-09-08 Bernhard Dr Janiak Viruzide und spermizide mit einem gehalt an quaternaeren ammoniumsalzen
DE3843126C3 (de) * 1988-12-22 1994-10-06 Octapharma Ag Verfahren zur Herstellung eines hochreinen Thrombinkonzentrates
JPH02182259A (ja) * 1989-01-06 1990-07-16 Ube Ind Ltd 止血用絆創膏
US5733572A (en) 1989-12-22 1998-03-31 Imarx Pharmaceutical Corp. Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
US7435425B2 (en) 2001-07-17 2008-10-14 Baxter International, Inc. Dry hemostatic compositions and methods for their preparation
US6066325A (en) * 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US6063061A (en) 1996-08-27 2000-05-16 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US6045570A (en) * 1997-02-11 2000-04-04 Biointerventional Corporation Biological sealant mixture and system for use in percutaneous occlusion of puncture sites and tracts in the human body and method
US5908054A (en) * 1997-06-16 1999-06-01 Fusion Medical Technologies, Inc. Fluid dispersion and delivery assembly and method
AT407117B (de) * 1997-09-19 2000-12-27 Immuno Ag Fibrinschwamm
IT1307887B1 (it) 1999-06-18 2001-11-19 Perini Fabio Spa Metodo e dispositivo di goffratura per la produzione di materialenastriforme multivelo, e prodotto cosi' ottenuto.
US6566345B2 (en) * 2000-04-28 2003-05-20 Fziomed, Inc. Polyacid/polyalkylene oxide foams and gels and methods for their delivery
WO2001097826A2 (en) 2000-06-16 2001-12-27 University Of Medicine And Dentistry Of New Jersey Hemostatic compositions, devices and methods
AT412445B (de) 2000-06-20 2005-03-25 Biering Wolfgang Flüssiges collagen-hämostatikum
US8187625B2 (en) * 2001-03-12 2012-05-29 Boston Scientific Scimed, Inc. Cross-linked gelatin composition comprising a wetting agent
CN1290586C (zh) 2001-12-21 2006-12-20 弗劳森公司 一种止血的试剂盒和制备止血剂的方法
ATE385777T1 (de) * 2002-03-20 2008-03-15 Elan Pharma Int Ltd Nanopartikelzusammensetzungen von mitogen- aktivierten protein (map) kinase inhibitoren
US20040105889A1 (en) * 2002-12-03 2004-06-03 Elan Pharma International Limited Low viscosity liquid dosage forms
US20040101546A1 (en) * 2002-11-26 2004-05-27 Gorman Anne Jessica Hemostatic wound dressing containing aldehyde-modified polysaccharide and hemostatic agents
US20040120993A1 (en) * 2002-12-20 2004-06-24 Guanghui Zhang Hemostatic wound dressing and fabric and methods of making and using same
US7927626B2 (en) 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
US7109163B2 (en) * 2004-01-30 2006-09-19 Ethicon, Inc. Hemostatic compositions and devices

Also Published As

Publication number Publication date
CA2495048C (en) 2013-10-08
EP1559438B1 (de) 2010-11-10
JP2005239713A (ja) 2005-09-08
US7109163B2 (en) 2006-09-19
JP2012210479A (ja) 2012-11-01
ES2352088T3 (es) 2011-02-15
JP5599846B2 (ja) 2014-10-01
US20050171001A1 (en) 2005-08-04
CA2495048A1 (en) 2005-07-30
DK1559438T3 (da) 2011-02-21
EP1559438A1 (de) 2005-08-03
JP5178992B2 (ja) 2013-04-10
DE602005024633D1 (de) 2010-12-23

Similar Documents

Publication Publication Date Title
DE602005024633D1 (de) Hämostatische Zusammensetzungen und Vorrichtungen
ATE457716T1 (de) Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung
ATE325628T1 (de) Verstärkte, implantierbare vorrichtungen
DE60117043D1 (de) Behandlung von mukositis
FR2894585B1 (fr) Copolymere comprenant des unites zwitterioniques et d'autres unites, composition comprenant le copolymere, et utilisation
Mistry et al. In vivo bone biocompatibility and degradation of porous fumarate‐based polymer/alumoxane nanocomposites for bone tissue engineering
ATE502596T1 (de) Schmales zahnimplantat und zugeordnete teile
ATE437663T1 (de) Legierungszusammensetzungen und diese enthaltende vorrichtungen
BRPI0607483A2 (pt) microimplantes para administração ocular
ATE422880T1 (de) Heterofunktionelle copolymere von glycerol und polyethylenglykol, ihre konjugate und zusammensetzungen
WO2009100280A3 (en) 3-dimensional silk hydroxyapatite compositions
WO2005014533A3 (en) Aryl and heteroaryl compounds, compositions, and methods of use
CA2502394A1 (en) Surgical articles
BRPI0412526A (pt) composto, uso de um composto, composição farmacêutica, formulação em aerossol farmacêutica, e, método para o tratamento de um paciente humano ou animal com uma condição anti-inflamatória e/ou alérgica
DE60330187D1 (de) Fluoralkoxy-substituierte 1, 3-dihydro-isoindolyl-verbindungen und ihre pharmazeutischen verwendungen
WO2005034726A3 (en) Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects
DE60329514D1 (de) Biologische modulare tibiateil- und femurteilklötze zur verwendung bei totaler kniegelenkrekonstruktion
BR0306924A (pt) Composição termoplástica superabsorvente e artigo incluindo a mesma
DE602005026117D1 (de) Komprimierte pharmazeutische zusammensetzungen mit peg und elektrolyten
DE60329415D1 (de) Pyridine zur behandlung von verletztemsäugetiernervengewebe
WO2007055950A3 (en) Polycation-polyanion complexes, compositions and methods of use thereof
ATE415968T1 (de) 3,11b-cis-dihydrotetrabanezin zur behandlung von schizophrenie und anderen psychosen
DE602004025808D1 (de) Gaboxadol zur behandlung von depressionen und anderen affektiven störungen
MX2009011641A (es) Agentes de liberacion para dispositivo de implante y metodos para utilizar los mismos.
BRPI0408827A (pt) composições oftálmicas preservadas

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties