ATE412905T1 - Diagnoseverfahren für lebersteatose unter verwendung biochemischer marker - Google Patents

Diagnoseverfahren für lebersteatose unter verwendung biochemischer marker

Info

Publication number
ATE412905T1
ATE412905T1 AT06710408T AT06710408T ATE412905T1 AT E412905 T1 ATE412905 T1 AT E412905T1 AT 06710408 T AT06710408 T AT 06710408T AT 06710408 T AT06710408 T AT 06710408T AT E412905 T1 ATE412905 T1 AT E412905T1
Authority
AT
Austria
Prior art keywords
diagnostic methods
biochemical markers
liver steatosis
patient
drawn
Prior art date
Application number
AT06710408T
Other languages
English (en)
Inventor
Thierry Poynard
Original Assignee
Assist Publ Hopitaux De Paris
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Assist Publ Hopitaux De Paris filed Critical Assist Publ Hopitaux De Paris
Application granted granted Critical
Publication of ATE412905T1 publication Critical patent/ATE412905T1/de

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medical Informatics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Databases & Information Systems (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Evolutionary Biology (AREA)
  • Epidemiology (AREA)
  • Theoretical Computer Science (AREA)
  • Data Mining & Analysis (AREA)
  • Hematology (AREA)
  • Evolutionary Computation (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Bioethics (AREA)
  • Artificial Intelligence (AREA)
  • Zoology (AREA)
  • Software Systems (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
AT06710408T 2005-02-03 2006-02-03 Diagnoseverfahren für lebersteatose unter verwendung biochemischer marker ATE412905T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/050,396 US7860656B2 (en) 2005-02-03 2005-02-03 Diagnosis method of hepatic steatosis using biochemical markers

Publications (1)

Publication Number Publication Date
ATE412905T1 true ATE412905T1 (de) 2008-11-15

Family

ID=36097137

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06710408T ATE412905T1 (de) 2005-02-03 2006-02-03 Diagnoseverfahren für lebersteatose unter verwendung biochemischer marker

Country Status (13)

Country Link
US (2) US7860656B2 (de)
EP (1) EP1856536B1 (de)
JP (1) JP2008529030A (de)
CN (1) CN101175998A (de)
AT (1) ATE412905T1 (de)
BR (1) BRPI0606840A2 (de)
CA (1) CA2596682A1 (de)
DE (1) DE602006003414D1 (de)
IL (1) IL185021A0 (de)
MA (1) MA29282B1 (de)
MX (1) MX2007009427A (de)
RU (1) RU2403576C2 (de)
WO (1) WO2006082522A1 (de)

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WO2008031051A2 (en) * 2006-09-08 2008-03-13 United Therapeutics Corporation Clinical diagnosis of hepatic fibrosis using a novel panel of human serum protein biomarkers
US20100130600A1 (en) * 2007-03-30 2010-05-27 Cedars-Sinai Medical Center Lipoprotein lipase and its effect on statin treatments
ES2402142T3 (es) * 2007-11-02 2013-04-29 Metabolon, Inc. Biomarcadores para la enfermedad del hígado graso y métodos que utilizan los mismos
JP2009114092A (ja) * 2007-11-02 2009-05-28 Mcbi:Kk 慢性肝炎、肝硬変、肝がんの分別診断のための新規バイオマーカーおよび該バイオマーカーを用いた慢性肝炎、肝硬変、肝がんの分別診断方法
WO2009069776A1 (ja) * 2007-11-30 2009-06-04 National University Corporation Hokkaido University 糖鎖分析による肝疾患の診断方法
AU2009259540B2 (en) * 2008-05-28 2015-11-05 Basf Se Means and methods for assessing liver toxicity
EP2157431A1 (de) 2008-08-11 2010-02-24 One Way Liver Genomics, S.L. Verfahren zur NASH-Diagnose unter Verwendung von Stoffwechselprofilen
EP2342569A4 (de) * 2008-08-28 2012-07-04 Salutria Pharmaceuticals Llc Screeningverfahren zur identifizierung von risikopatienten für unerwünschte hepatologische ereignisse
WO2010051483A1 (en) * 2008-10-31 2010-05-06 Cedars-Sinai Medical Center Methods of diagnosing insulin resistance and sensitivity
ES2621838T3 (es) 2008-11-18 2017-07-05 Universite D'angers Método in vitro no invasivo para la cuantificación de lesiones hepáticas
WO2010097472A1 (en) * 2009-02-26 2010-09-02 Universite D'angers Improved diagnosis of liver fibrosis or cirrhosis
CN105866423A (zh) * 2009-05-14 2016-08-17 牛津大学之校长及学者 使用一组新型低丰度人类血浆蛋白生物标记对肝纤维化进行临床诊断
EP2309276A1 (de) 2009-09-22 2011-04-13 One Way Liver Genomics, S.L. Verfahren zur Diagnose von nichtalkoholischer Steatohepatitis basierend auf einem metabolomischen Profil
EP2327988A1 (de) 2009-11-28 2011-06-01 Assistance Publique Hôpitaux De Paris Verfahren zur Diagnose von fibrotischen Erkrankungen
EP2567241B1 (de) * 2010-05-03 2015-11-04 The Cleveland Clinic Foundation Erkennung und überwachung von nicht alkoholbedingter fettleber
EP2418285A1 (de) * 2010-08-09 2012-02-15 Universiteit Maastricht Verfahren zur Diagnose von Fettlebererkrankungen, insbesondere von nicht alkoholischer Steato-Hepatitis
FR2971256B1 (fr) 2011-02-09 2024-09-27 Bio Rad Pasteur Combinaison de biomarqueurs pour la detection et l'evaluation d'une fibrose hepatique
RU2476154C1 (ru) * 2011-08-12 2013-02-27 Государственное образовательное учреждение высшего профессионального образования "Смоленская государственная медицинская академия" Министерства здравоохранения и социального развития Российской Федерации Способ диагностики алкогольной болезни печени
WO2013045500A1 (en) * 2011-09-26 2013-04-04 Universite Pierre Et Marie Curie (Paris 6) Method for determining a predictive function for discriminating patients according to their disease activity status
EP2600266A1 (de) 2011-12-02 2013-06-05 Biopredictive Verfahren zur Diagnose von fibrotischen Erkrankungen
EP2810079A4 (de) * 2012-01-31 2015-08-05 Teknologian Tutkimuskeskus Vtt Oy Verfahren zur bestimmung der leberfettmenge und verfahren zur diagnose von nafld
WO2014049131A1 (en) * 2012-09-28 2014-04-03 Université d'Angers Accurate blood test for the non-invasive diagnosis of non-alcoholic steatohepatitis
ES2821383T3 (es) * 2012-10-17 2021-04-26 Enterome Firmas genéticas de trastornos inflamatorios relacionados con el hígado y la enfermedad de Crohn
RU2545990C2 (ru) * 2013-07-16 2015-04-10 Государственное бюджетное учреждение здравоохранения города Москвы Московский клинический научно-практический центр Департамента здравоохранения города Москвы Способ дифференциальной диагностики стеатоза печени и стеатогепатита
RU2557927C1 (ru) * 2014-06-05 2015-07-27 Государственное бюджетное образовательное учреждение высшего профессионального образования "Тихоокеанский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО ТГМУ Минздрава России) Способ диагностики фиброза печени при хроническом вирусном гепатите с
FR3023003B1 (fr) 2014-06-27 2016-07-15 Bio-Rad Innovations Combinaison synergique de biomarqueurs pour la detection et l'evaluation d'une fibrose hepatique
JP2018512208A (ja) 2015-03-17 2018-05-17 セルビシオ アンダルス デ サルＳｅｒｖｉｃｉｏ Ａｎｄａｌｕｚ Ｄｅ Ｓａｌｕｄ 肝臓の病変を定量化または決定するためのｍｒ（磁気共鳴）画像のコンピュータ化された光学的分析方法
WO2017210147A1 (en) 2016-05-29 2017-12-07 Wei Jia Liver disease-related biomarkers and methods of use thereof
CN106127256A (zh) * 2016-06-30 2016-11-16 张云超 一种肝纤维化检测方法及装置
EP3267199A1 (de) * 2016-07-06 2018-01-10 One Way Liver S.L. Diagnostische methoden basierend auf lipidprofilen
EP3296744A1 (de) * 2016-09-16 2018-03-21 Biopredictive Verfahren zur diagnose nichtalkoholischer fettlebererkrankungen
CN106771201A (zh) * 2016-12-05 2017-05-31 江西惠肽生物科技有限公司 用于肝纤维化诊断试剂盒及其检测方法
WO2018156717A1 (en) 2017-02-24 2018-08-30 The Cleveland Clinic Foundation Method and apparatus for time-differential deployment of an endovascular device within a body lumen
EP3373012A1 (de) 2017-03-07 2018-09-12 Biopredictive Verfahren zur diagnose von arzneimittelinduzierter leberverletzung
CN111183360B (zh) 2017-07-19 2024-10-18 生物辐射欧洲有限公司 同时评估非酒精性脂肪性肝炎和肝纤维化状态的生物标志物组合
US12360113B2 (en) 2017-10-16 2025-07-15 Biopredictive Method of prognosis and follow up of primary liver cancer
EP3470843A1 (de) 2017-10-16 2019-04-17 Biopredictive Verfahren zur prognose von primärem leberkrebs
CN108565024B (zh) * 2018-03-19 2020-05-05 首都医科大学附属北京地坛医院 一种确定单发的hbv相关原发性小肝癌术后1年内复发风险的系统
CN108417267B (zh) * 2018-03-19 2020-05-05 首都医科大学附属北京地坛医院 一种确定肝硬化肝肾综合征患者短期预后的系统
CN108932976A (zh) * 2018-06-11 2018-12-04 西安医学院 一种非酒精性脂肪性肝病无创性诊断程序
RU2684201C1 (ru) * 2018-07-05 2019-04-04 Федеральное государственное бюджетное военное образовательное учреждение высшего образования Военно-медицинская академия имени С.М. Кирова Министерства обороны Российской Федерации (ВМедА) Способ скрининговой диагностики жировой дегенерации печени при абдоминальном ожирении
EP3599615A1 (de) * 2018-07-27 2020-01-29 Biopredictive Verfahren zur diagnose von lebersteatose
EP3836929A1 (de) * 2018-08-14 2021-06-23 Camp4 Therapeutics Corporation Verfahren zur behandlung von lebererkrankungen
JP7576378B2 (ja) * 2019-07-05 2024-10-31 モレキュラー ユー コーポレーション 個別化された分子ベースの健康管理およびデジタル相談および治療のための方法およびシステム
CN111583993A (zh) * 2020-05-29 2020-08-25 杭州广科安德生物科技有限公司 构建体外检测癌症的数学模型的方法及其应用
RU2753455C1 (ru) * 2020-12-11 2021-08-16 Федеральное государственное унитарное предприятие «Государственный научно-исследовательский институт особо чистых биопрепаратов» Федерального медико-биологического агентства Способ дифференциальной диагностики стеатоза печени и неалкогольного стеатогепатита у мужчин
RU2755974C1 (ru) * 2021-03-11 2021-09-23 Федеральное государственное бюджетное образовательное учреждение высшего образования "Пермский государственный медицинский университет имени академика Е.А. Вагнера" Министерства здравоохранения Российской Федерации Способ диагностики неалкогольного стеатоза печени
RU2763257C1 (ru) * 2021-05-14 2021-12-28 Федеральное государственное бюджетное учреждение "Детский научно-клинический центр инфекционных болезней Федерального медико-биологического агентства" Способ диагностики стадии фиброза печени при хронических заболеваниях печени у детей
KR20240126870A (ko) 2021-12-22 2024-08-21 캠프4 테라퓨틱스 코포레이션 조절 rna들을 표적으로 하는 안티센스 올리고뉴클레오티드를 사용한 유전자 전사의 조절
EP4555924A1 (de) 2023-11-15 2025-05-21 Assistance Publique - Hôpitaux de Paris Verfahren zur bestimmung der gebrechlichkeit unter verwendung von anästhesiedaten

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US7856319B2 (en) * 2005-02-03 2010-12-21 Assistance Publique-Hopitaux De Paris (Ap-Hp) Diagnosis method of alcoholic steato-hepatitis using biochemical markers

Also Published As

Publication number Publication date
EP1856536B1 (de) 2008-10-29
US20060173629A1 (en) 2006-08-03
US7860656B2 (en) 2010-12-28
WO2006082522A1 (en) 2006-08-10
RU2403576C2 (ru) 2010-11-10
EP1856536A1 (de) 2007-11-21
JP2008529030A (ja) 2008-07-31
US20090111132A1 (en) 2009-04-30
MX2007009427A (es) 2008-03-06
BRPI0606840A2 (pt) 2010-03-09
RU2007132921A (ru) 2009-03-10
MA29282B1 (fr) 2008-02-01
DE602006003414D1 (de) 2008-12-11
CA2596682A1 (en) 2006-08-10
IL185021A0 (en) 2007-12-03
CN101175998A (zh) 2008-05-07

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