ATE496995T1 - Verfahren zur herstellung mikrobieller transglutaminase - Google Patents
Verfahren zur herstellung mikrobieller transglutaminaseInfo
- Publication number
- ATE496995T1 ATE496995T1 AT04717856T AT04717856T ATE496995T1 AT E496995 T1 ATE496995 T1 AT E496995T1 AT 04717856 T AT04717856 T AT 04717856T AT 04717856 T AT04717856 T AT 04717856T AT E496995 T1 ATE496995 T1 AT E496995T1
- Authority
- AT
- Austria
- Prior art keywords
- actinomycetes
- microbial transglutaminase
- producing microbial
- microbial
- neutral metalloprotease
- Prior art date
Links
- 230000000813 microbial effect Effects 0.000 title abstract 4
- 108060008539 Transglutaminase Proteins 0.000 title abstract 2
- 102000003601 transglutaminase Human genes 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 241000186361 Actinobacteria <class> Species 0.000 abstract 3
- 102000005741 Metalloproteases Human genes 0.000 abstract 3
- 108010006035 Metalloproteases Proteins 0.000 abstract 3
- 230000007935 neutral effect Effects 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 238000012258 culturing Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003061623 | 2003-03-07 | ||
| PCT/JP2004/002923 WO2004078973A1 (ja) | 2003-03-07 | 2004-03-05 | 微生物トランスグルタミナーゼの製造法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE496995T1 true ATE496995T1 (de) | 2011-02-15 |
Family
ID=32958965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04717856T ATE496995T1 (de) | 2003-03-07 | 2004-03-05 | Verfahren zur herstellung mikrobieller transglutaminase |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7704707B2 (de) |
| EP (1) | EP1602722B1 (de) |
| JP (1) | JP4482938B2 (de) |
| KR (1) | KR20050106502A (de) |
| CN (1) | CN100381569C (de) |
| AT (1) | ATE496995T1 (de) |
| BR (1) | BRPI0407911A (de) |
| CA (1) | CA2518049C (de) |
| DE (1) | DE602004031198D1 (de) |
| DK (1) | DK1602722T3 (de) |
| ES (1) | ES2356149T3 (de) |
| RU (1) | RU2316594C2 (de) |
| WO (1) | WO2004078973A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1253195B1 (de) * | 2000-01-21 | 2008-10-15 | Ajinomoto Co., Inc. | Verfahren zur herstellung von l-lysin |
| ES2356149T3 (es) | 2003-03-07 | 2011-04-05 | Ajinomoto Co., Inc. | Procedimiento para producir transglutaminasa microbiana. |
| DK1748077T3 (da) * | 2004-04-20 | 2013-04-08 | Ajinomoto Kk | Fremgangsmåde til fremstilling af protein |
| JP4631436B2 (ja) * | 2004-12-22 | 2011-02-16 | 岡山県 | メタロエンドペプチダーゼ |
| CN101248176B (zh) * | 2005-08-30 | 2011-05-11 | 味之素株式会社 | 制备蛋白酶活性降低的含转谷氨酰胺酶制品的方法 |
| CN101248185A (zh) * | 2005-08-30 | 2008-08-20 | 味之素株式会社 | 测定含转谷氨酰胺酶制品的蛋白酶活性的方法和粘结用转谷氨酰胺酶制剂 |
| CN101631860B (zh) * | 2007-02-15 | 2012-07-18 | 味之素株式会社 | 引入二硫键的转谷氨酰胺酶 |
| JP5093228B2 (ja) | 2007-03-29 | 2012-12-12 | 味の素株式会社 | 接着用酵素製剤及び接着成形食品の製造方法 |
| JPWO2009066785A1 (ja) | 2007-11-19 | 2011-04-07 | 味の素株式会社 | 繊維加工物及びその製造法 |
| JP5499714B2 (ja) * | 2008-02-15 | 2014-05-21 | 味の素株式会社 | 腸管免疫賦活剤 |
| CN102089437B (zh) * | 2008-07-09 | 2014-11-05 | 味之素株式会社 | 生产氨基羟基苯甲酸盐类化合物的方法 |
| TWI444146B (zh) | 2008-09-25 | 2014-07-11 | Ajinomoto Kk | 黏著成型食品用酵素製劑及黏著成型食品之製造方法 |
| CN102341497B (zh) | 2009-03-06 | 2013-11-06 | 味之素株式会社 | 放线菌来源的耐热性转谷氨酰胺酶 |
| CN103608463A (zh) | 2011-06-23 | 2014-02-26 | 味之素株式会社 | 由使具有免疫球蛋白折叠结构的蛋白和能够形成亚单元结构的蛋白融合而得到的单体蛋白组成的多聚体蛋白的制备方法 |
| JP6064912B2 (ja) | 2011-10-25 | 2017-01-25 | 味の素株式会社 | タンパク質の分泌生産法 |
| CN103946372B (zh) * | 2011-11-02 | 2016-06-08 | 味之素株式会社 | 用于分泌产生蛋白质的方法 |
| IN2014CN04039A (de) | 2011-11-02 | 2015-10-23 | Ajinomoto Kk | |
| WO2013179711A1 (ja) | 2012-05-29 | 2013-12-05 | 味の素株式会社 | ３－アセチルアミノ－４－ヒドロキシ安息香酸の製造方法 |
| US10538722B2 (en) | 2014-11-10 | 2020-01-21 | Novozymes A/S | Metalloproteases and uses thereof |
| CN108103041A (zh) * | 2018-02-02 | 2018-06-01 | 泰兴市东圣生物科技有限公司 | 一种热稳定微生物转谷氨酰胺酶及其编码基因 |
| CN113528479B (zh) * | 2020-04-13 | 2023-01-24 | 中国科学院微生物研究所 | 一种转谷氨酰胺酶的高效制备方法及其专用工程菌 |
| CN113528478B (zh) * | 2020-04-13 | 2023-01-20 | 中国科学院微生物研究所 | 一种高效生产转谷氨酰胺酶的方法及其专用工程菌 |
| KR102277403B1 (ko) * | 2021-01-27 | 2021-07-14 | 씨제이제일제당 주식회사 | 신규한 리보뉴클레아제 p 변이체 및 이를 이용한 l-글루탐산 생산 방법 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0665280B2 (ja) * | 1987-03-04 | 1994-08-24 | 味の素株式会社 | タンパクゲル化剤及びそれを用いるタンパクのゲル化方法 |
| TW306932B (de) * | 1993-08-27 | 1997-06-01 | Holland Sweetener Co | |
| AU705803B2 (en) * | 1994-08-26 | 1999-06-03 | Novozymes A/S | Microbial transglutaminases, their production and use |
| JPH0970291A (ja) | 1995-06-30 | 1997-03-18 | Ajinomoto Co Inc | 人工トランスポゾンを用いた遺伝子増幅方法 |
| CN1174889A (zh) * | 1997-06-16 | 1998-03-04 | 中国医学科学院医药生物技术研究所 | 一种链霉菌产生的新型纤溶酶 |
| RU2224796C2 (ru) * | 1999-09-30 | 2004-02-27 | Адзиномото Ко., Инк. | Способ получения гетерологичного секреторного белка |
| ATE532870T1 (de) * | 1999-09-30 | 2011-11-15 | Ajinomoto Kk | Verfahren zur herstellung von transglutaminase |
| EP1375664B1 (de) * | 2001-03-30 | 2009-11-04 | Ajinomoto Co., Inc. | Verfahren zur sekretion und produktion von protein |
| RU2209244C2 (ru) * | 2001-04-28 | 2003-07-27 | Закрытое акционерное общество "АСГЛ-Фармацевтические Инновации" | Нуклеиновая кислота, кодирующая лидерную последовательность (варианты), вектор на основе плазмиды р6803-platform (варианты), лидерный пептид (варианты) и способ получения белков |
| ES2356149T3 (es) * | 2003-03-07 | 2011-04-05 | Ajinomoto Co., Inc. | Procedimiento para producir transglutaminasa microbiana. |
| DK1748077T3 (da) * | 2004-04-20 | 2013-04-08 | Ajinomoto Kk | Fremgangsmåde til fremstilling af protein |
-
2004
- 2004-03-05 ES ES04717856T patent/ES2356149T3/es not_active Expired - Lifetime
- 2004-03-05 JP JP2005503155A patent/JP4482938B2/ja not_active Expired - Fee Related
- 2004-03-05 DE DE602004031198T patent/DE602004031198D1/de not_active Expired - Lifetime
- 2004-03-05 WO PCT/JP2004/002923 patent/WO2004078973A1/ja not_active Ceased
- 2004-03-05 KR KR1020057016640A patent/KR20050106502A/ko not_active Ceased
- 2004-03-05 CA CA2518049A patent/CA2518049C/en not_active Expired - Lifetime
- 2004-03-05 DK DK04717856.1T patent/DK1602722T3/da active
- 2004-03-05 RU RU2005127869/13A patent/RU2316594C2/ru active
- 2004-03-05 EP EP04717856A patent/EP1602722B1/de not_active Expired - Lifetime
- 2004-03-05 BR BRPI0407911-6A patent/BRPI0407911A/pt not_active Application Discontinuation
- 2004-03-05 AT AT04717856T patent/ATE496995T1/de not_active IP Right Cessation
- 2004-03-05 CN CNB2004800062248A patent/CN100381569C/zh not_active Expired - Fee Related
-
2005
- 2005-09-06 US US11/218,780 patent/US7704707B2/en not_active Expired - Lifetime
-
2010
- 2010-03-01 US US12/714,853 patent/US8105802B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US7704707B2 (en) | 2010-04-27 |
| RU2005127869A (ru) | 2006-02-10 |
| DK1602722T3 (da) | 2011-05-16 |
| CN1759180A (zh) | 2006-04-12 |
| DE602004031198D1 (de) | 2011-03-10 |
| WO2004078973A1 (ja) | 2004-09-16 |
| KR20050106502A (ko) | 2005-11-09 |
| CA2518049C (en) | 2013-05-07 |
| US8105802B2 (en) | 2012-01-31 |
| EP1602722A4 (de) | 2006-08-02 |
| RU2316594C2 (ru) | 2008-02-10 |
| CA2518049A1 (en) | 2004-09-16 |
| CN100381569C (zh) | 2008-04-16 |
| US20100159560A1 (en) | 2010-06-24 |
| JP4482938B2 (ja) | 2010-06-16 |
| ES2356149T3 (es) | 2011-04-05 |
| EP1602722B1 (de) | 2011-01-26 |
| JPWO2004078973A1 (ja) | 2006-06-08 |
| BRPI0407911A (pt) | 2006-02-14 |
| EP1602722A1 (de) | 2005-12-07 |
| US20060019367A1 (en) | 2006-01-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |