ATE496995T1 - Verfahren zur herstellung mikrobieller transglutaminase - Google Patents
Verfahren zur herstellung mikrobieller transglutaminaseInfo
- Publication number
- ATE496995T1 ATE496995T1 AT04717856T AT04717856T ATE496995T1 AT E496995 T1 ATE496995 T1 AT E496995T1 AT 04717856 T AT04717856 T AT 04717856T AT 04717856 T AT04717856 T AT 04717856T AT E496995 T1 ATE496995 T1 AT E496995T1
- Authority
- AT
- Austria
- Prior art keywords
- actinomycetes
- microbial transglutaminase
- producing microbial
- microbial
- neutral metalloprotease
- Prior art date
Links
- 230000000813 microbial effect Effects 0.000 title abstract 4
- 108060008539 Transglutaminase Proteins 0.000 title abstract 2
- 102000003601 transglutaminase Human genes 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 241000186361 Actinobacteria <class> Species 0.000 abstract 3
- 102000005741 Metalloproteases Human genes 0.000 abstract 3
- 108010006035 Metalloproteases Proteins 0.000 abstract 3
- 230000007935 neutral effect Effects 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 238000012258 culturing Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003061623 | 2003-03-07 | ||
| PCT/JP2004/002923 WO2004078973A1 (ja) | 2003-03-07 | 2004-03-05 | 微生物トランスグルタミナーゼの製造法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE496995T1 true ATE496995T1 (de) | 2011-02-15 |
Family
ID=32958965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04717856T ATE496995T1 (de) | 2003-03-07 | 2004-03-05 | Verfahren zur herstellung mikrobieller transglutaminase |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7704707B2 (de) |
| EP (1) | EP1602722B1 (de) |
| JP (1) | JP4482938B2 (de) |
| KR (1) | KR20050106502A (de) |
| CN (1) | CN100381569C (de) |
| AT (1) | ATE496995T1 (de) |
| BR (1) | BRPI0407911A (de) |
| CA (1) | CA2518049C (de) |
| DE (1) | DE602004031198D1 (de) |
| DK (1) | DK1602722T3 (de) |
| ES (1) | ES2356149T3 (de) |
| RU (1) | RU2316594C2 (de) |
| WO (1) | WO2004078973A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0016995B1 (pt) * | 2000-01-21 | 2016-03-08 | Ajinomoto Kk | bactéria escherichia coli geneticamente modificada, e, método para produzir l-lisina |
| CA2518049C (en) * | 2003-03-07 | 2013-05-07 | Ajinomoto Co., Inc. | Method of producing microbial transglutaminase |
| DK1748077T3 (da) * | 2004-04-20 | 2013-04-08 | Ajinomoto Kk | Fremgangsmåde til fremstilling af protein |
| JP4631436B2 (ja) * | 2004-12-22 | 2011-02-16 | 岡山県 | メタロエンドペプチダーゼ |
| CN101248176B (zh) * | 2005-08-30 | 2011-05-11 | 味之素株式会社 | 制备蛋白酶活性降低的含转谷氨酰胺酶制品的方法 |
| TW200801198A (en) * | 2005-08-30 | 2008-01-01 | Ajinomoto Kk | Method for measuring protease activity of transglutaminase and transglutaminase composition |
| JPWO2008099898A1 (ja) * | 2007-02-15 | 2010-05-27 | 味の素株式会社 | ジスルフィド結合導入トランスグルタミナーゼ |
| EP2138049B1 (de) | 2007-03-29 | 2014-06-25 | Ajinomoto Co., Inc. | Enzymherstellung für adhäsion und verfahren zur herstellung eines adhäsionsgeformten lebensmittelprodukts |
| KR20100085083A (ko) | 2007-11-19 | 2010-07-28 | 아지노모토 가부시키가이샤 | 섬유 가공물 및 이의 제조법 |
| WO2009102050A1 (ja) * | 2008-02-15 | 2009-08-20 | Ajinomoto Co., Inc. | 腸管免疫賦活剤 |
| WO2010005099A1 (ja) * | 2008-07-09 | 2010-01-14 | 味の素株式会社 | アミノヒドロキシ安息香酸類の製造方法 |
| TWI444146B (zh) | 2008-09-25 | 2014-07-11 | Ajinomoto Kk | 黏著成型食品用酵素製劑及黏著成型食品之製造方法 |
| WO2010101256A1 (ja) | 2009-03-06 | 2010-09-10 | 味の素株式会社 | 放線菌由来の耐熱性トランスグルタミナーゼ |
| CN107365388B (zh) | 2011-06-23 | 2021-05-14 | 味之素株式会社 | 多聚体蛋白的制备方法 |
| CN103917656B (zh) | 2011-10-25 | 2016-09-28 | 味之素株式会社 | 蛋白质的分泌产生方法 |
| WO2013065869A1 (en) | 2011-11-02 | 2013-05-10 | Ajinomoto Co.,Inc. | Method for secretory production of protein |
| WO2013065772A1 (ja) | 2011-11-02 | 2013-05-10 | 味の素株式会社 | タンパク質の分泌生産法 |
| JP6183358B2 (ja) | 2012-05-29 | 2017-08-23 | 味の素株式会社 | ３−アセチルアミノ−４−ヒドロキシ安息香酸の製造方法 |
| EP3218473B1 (de) * | 2014-11-10 | 2020-04-08 | Novozymes A/S | Metalloproteasen und ihren verwendung |
| CN108103041A (zh) * | 2018-02-02 | 2018-06-01 | 泰兴市东圣生物科技有限公司 | 一种热稳定微生物转谷氨酰胺酶及其编码基因 |
| CN113528478B (zh) * | 2020-04-13 | 2023-01-20 | 中国科学院微生物研究所 | 一种高效生产转谷氨酰胺酶的方法及其专用工程菌 |
| CN113528479B (zh) * | 2020-04-13 | 2023-01-24 | 中国科学院微生物研究所 | 一种转谷氨酰胺酶的高效制备方法及其专用工程菌 |
| KR102277403B1 (ko) * | 2021-01-27 | 2021-07-14 | 씨제이제일제당 주식회사 | 신규한 리보뉴클레아제 p 변이체 및 이를 이용한 l-글루탐산 생산 방법 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0665280B2 (ja) * | 1987-03-04 | 1994-08-24 | 味の素株式会社 | タンパクゲル化剤及びそれを用いるタンパクのゲル化方法 |
| TW306932B (de) * | 1993-08-27 | 1997-06-01 | Holland Sweetener Co | |
| DE69535037T2 (de) * | 1994-08-26 | 2006-12-07 | Novozymes A/S | Mikrobielle transglutaminasen, ihre herstellung und ihre verwendung |
| JPH0970291A (ja) | 1995-06-30 | 1997-03-18 | Ajinomoto Co Inc | 人工トランスポゾンを用いた遺伝子増幅方法 |
| CN1174889A (zh) * | 1997-06-16 | 1998-03-04 | 中国医学科学院医药生物技术研究所 | 一种链霉菌产生的新型纤溶酶 |
| ATE532870T1 (de) * | 1999-09-30 | 2011-11-15 | Ajinomoto Kk | Verfahren zur herstellung von transglutaminase |
| RU2224796C2 (ru) * | 1999-09-30 | 2004-02-27 | Адзиномото Ко., Инк. | Способ получения гетерологичного секреторного белка |
| DE60234247D1 (de) * | 2001-03-30 | 2009-12-17 | Ajinomoto Kk | Verfahren zur sekretion und produktion von protein |
| RU2209244C2 (ru) * | 2001-04-28 | 2003-07-27 | Закрытое акционерное общество "АСГЛ-Фармацевтические Инновации" | Нуклеиновая кислота, кодирующая лидерную последовательность (варианты), вектор на основе плазмиды р6803-platform (варианты), лидерный пептид (варианты) и способ получения белков |
| CA2518049C (en) * | 2003-03-07 | 2013-05-07 | Ajinomoto Co., Inc. | Method of producing microbial transglutaminase |
| DK1748077T3 (da) * | 2004-04-20 | 2013-04-08 | Ajinomoto Kk | Fremgangsmåde til fremstilling af protein |
-
2004
- 2004-03-05 CA CA2518049A patent/CA2518049C/en not_active Expired - Lifetime
- 2004-03-05 JP JP2005503155A patent/JP4482938B2/ja not_active Expired - Fee Related
- 2004-03-05 RU RU2005127869/13A patent/RU2316594C2/ru active
- 2004-03-05 BR BRPI0407911-6A patent/BRPI0407911A/pt not_active Application Discontinuation
- 2004-03-05 ES ES04717856T patent/ES2356149T3/es not_active Expired - Lifetime
- 2004-03-05 DK DK04717856.1T patent/DK1602722T3/da active
- 2004-03-05 AT AT04717856T patent/ATE496995T1/de not_active IP Right Cessation
- 2004-03-05 EP EP04717856A patent/EP1602722B1/de not_active Expired - Lifetime
- 2004-03-05 CN CNB2004800062248A patent/CN100381569C/zh not_active Expired - Fee Related
- 2004-03-05 WO PCT/JP2004/002923 patent/WO2004078973A1/ja not_active Ceased
- 2004-03-05 KR KR1020057016640A patent/KR20050106502A/ko not_active Ceased
- 2004-03-05 DE DE602004031198T patent/DE602004031198D1/de not_active Expired - Lifetime
-
2005
- 2005-09-06 US US11/218,780 patent/US7704707B2/en not_active Expired - Lifetime
-
2010
- 2010-03-01 US US12/714,853 patent/US8105802B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1602722A4 (de) | 2006-08-02 |
| KR20050106502A (ko) | 2005-11-09 |
| ES2356149T3 (es) | 2011-04-05 |
| JPWO2004078973A1 (ja) | 2006-06-08 |
| CA2518049A1 (en) | 2004-09-16 |
| JP4482938B2 (ja) | 2010-06-16 |
| US8105802B2 (en) | 2012-01-31 |
| RU2005127869A (ru) | 2006-02-10 |
| WO2004078973A1 (ja) | 2004-09-16 |
| CA2518049C (en) | 2013-05-07 |
| BRPI0407911A (pt) | 2006-02-14 |
| US7704707B2 (en) | 2010-04-27 |
| US20060019367A1 (en) | 2006-01-26 |
| CN1759180A (zh) | 2006-04-12 |
| US20100159560A1 (en) | 2010-06-24 |
| RU2316594C2 (ru) | 2008-02-10 |
| DK1602722T3 (da) | 2011-05-16 |
| EP1602722A1 (de) | 2005-12-07 |
| DE602004031198D1 (de) | 2011-03-10 |
| CN100381569C (zh) | 2008-04-16 |
| EP1602722B1 (de) | 2011-01-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |