ATE498691T1 - Herstellung von monatin und monatinvorstufen - Google Patents
Herstellung von monatin und monatinvorstufenInfo
- Publication number
- ATE498691T1 ATE498691T1 AT04795689T AT04795689T ATE498691T1 AT E498691 T1 ATE498691 T1 AT E498691T1 AT 04795689 T AT04795689 T AT 04795689T AT 04795689 T AT04795689 T AT 04795689T AT E498691 T1 ATE498691 T1 AT E498691T1
- Authority
- AT
- Austria
- Prior art keywords
- monatin
- indole
- methods
- indol
- ylmethyl
- Prior art date
Links
- RMLYXMMBIZLGAQ-UHFFFAOYSA-N (-)-monatin Natural products C1=CC=C2C(CC(O)(CC(N)C(O)=O)C(O)=O)=CNC2=C1 RMLYXMMBIZLGAQ-UHFFFAOYSA-N 0.000 title abstract 3
- RMLYXMMBIZLGAQ-HZMBPMFUSA-N (2s,4s)-4-amino-2-hydroxy-2-(1h-indol-3-ylmethyl)pentanedioic acid Chemical compound C1=CC=C2C(C[C@](O)(C[C@H](N)C(O)=O)C(O)=O)=CNC2=C1 RMLYXMMBIZLGAQ-HZMBPMFUSA-N 0.000 title abstract 3
- 239000002243 precursor Substances 0.000 title 1
- 238000000034 method Methods 0.000 abstract 5
- SLWQCDYJBNGHQV-UHFFFAOYSA-N 2-hydroxy-2-(1h-indol-3-ylmethyl)-4-oxopentanedioic acid Chemical compound C1=CC=C2C(CC(O)(CC(=O)C(=O)O)C(O)=O)=CNC2=C1 SLWQCDYJBNGHQV-UHFFFAOYSA-N 0.000 abstract 2
- RSTKLPZEZYGQPY-UHFFFAOYSA-N 3-(indol-3-yl)pyruvic acid Chemical compound C1=CC=C2C(CC(=O)C(=O)O)=CNC2=C1 RSTKLPZEZYGQPY-UHFFFAOYSA-N 0.000 abstract 2
- 238000000338 in vitro Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- XGILAAMKEQUXLS-UHFFFAOYSA-N 3-(indol-3-yl)lactic acid Chemical compound C1=CC=C2C(CC(O)C(O)=O)=CNC2=C1 XGILAAMKEQUXLS-UHFFFAOYSA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 abstract 1
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Indole Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51340603P | 2003-10-21 | 2003-10-21 | |
| PCT/US2004/034558 WO2005042756A2 (en) | 2003-10-21 | 2004-10-21 | Production of monatin and monatin precursors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE498691T1 true ATE498691T1 (de) | 2011-03-15 |
Family
ID=34549274
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04795689T ATE498691T1 (de) | 2003-10-21 | 2004-10-21 | Herstellung von monatin und monatinvorstufen |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8206955B2 (de) |
| EP (2) | EP1678313B1 (de) |
| JP (1) | JP4829117B2 (de) |
| KR (1) | KR101158592B1 (de) |
| CN (2) | CN1890377B (de) |
| AT (1) | ATE498691T1 (de) |
| AU (1) | AU2004286207B2 (de) |
| BR (1) | BRPI0415763A (de) |
| DE (1) | DE602004031444D1 (de) |
| RU (1) | RU2006117353A (de) |
| WO (1) | WO2005042756A2 (de) |
| ZA (1) | ZA200604080B (de) |
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| US8372989B2 (en) | 2002-04-23 | 2013-02-12 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
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| RU2307871C2 (ru) | 2002-08-26 | 2007-10-10 | Адзиномото Ко., Инк. | НОВАЯ АЛЬДОЛАЗА И СПОСОБ ПОЛУЧЕНИЯ ЗАМЕЩЕННЫХ α-КЕТОКИСЛОТ |
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| US8076107B2 (en) * | 2007-10-01 | 2011-12-13 | Cargill, Incorporated | Production of monatin stereoisomers |
| US8003361B2 (en) * | 2007-10-01 | 2011-08-23 | Cargill Incorporated | Production of monatin enantiomers |
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| EP2479272A4 (de) | 2010-10-14 | 2013-11-20 | Ajinomoto Kk | Verfahren zur herstellung von monatin |
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| CN113237834B (zh) * | 2021-07-08 | 2021-09-14 | 成都信息工程大学 | 基于光自旋霍尔效应的手性分子手性分辨装置及方法 |
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-
2004
- 2004-10-21 EP EP04795689A patent/EP1678313B1/de not_active Expired - Lifetime
- 2004-10-21 WO PCT/US2004/034558 patent/WO2005042756A2/en not_active Ceased
- 2004-10-21 JP JP2006536714A patent/JP4829117B2/ja not_active Expired - Fee Related
- 2004-10-21 BR BRPI0415763-0A patent/BRPI0415763A/pt not_active Application Discontinuation
- 2004-10-21 KR KR1020067009839A patent/KR101158592B1/ko not_active Expired - Fee Related
- 2004-10-21 AU AU2004286207A patent/AU2004286207B2/en not_active Ceased
- 2004-10-21 AT AT04795689T patent/ATE498691T1/de not_active IP Right Cessation
- 2004-10-21 CN CN2004800348419A patent/CN1890377B/zh not_active Expired - Fee Related
- 2004-10-21 US US10/969,245 patent/US8206955B2/en not_active Expired - Fee Related
- 2004-10-21 RU RU2006117353/13A patent/RU2006117353A/ru not_active Application Discontinuation
- 2004-10-21 DE DE602004031444T patent/DE602004031444D1/de not_active Expired - Lifetime
- 2004-10-21 EP EP10009952.2A patent/EP2302067B1/de not_active Expired - Lifetime
- 2004-10-21 CN CN201310188490.8A patent/CN103555782B/zh not_active Expired - Fee Related
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2006
- 2006-05-19 ZA ZA200604080A patent/ZA200604080B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1890377B (zh) | 2013-06-05 |
| KR20060125761A (ko) | 2006-12-06 |
| WO2005042756A2 (en) | 2005-05-12 |
| EP2302067A1 (de) | 2011-03-30 |
| DE602004031444D1 (de) | 2011-03-31 |
| AU2004286207A1 (en) | 2005-05-12 |
| WO2005042756A3 (en) | 2005-11-24 |
| KR101158592B1 (ko) | 2012-06-22 |
| CN103555782A (zh) | 2014-02-05 |
| EP2302067B1 (de) | 2014-03-05 |
| JP4829117B2 (ja) | 2011-12-07 |
| ZA200604080B (en) | 2007-11-28 |
| EP1678313A2 (de) | 2006-07-12 |
| JP2007508840A (ja) | 2007-04-12 |
| US8206955B2 (en) | 2012-06-26 |
| AU2004286207B2 (en) | 2011-02-24 |
| EP1678313B1 (de) | 2011-02-16 |
| CN103555782B (zh) | 2017-04-12 |
| CN1890377A (zh) | 2007-01-03 |
| RU2006117353A (ru) | 2007-12-27 |
| BRPI0415763A (pt) | 2006-12-26 |
| US20050221455A1 (en) | 2005-10-06 |
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