ATE499449T1 - Verfahren zur herstellung optisch aktiver (s)- oder (r)-beta -aminosäuren und optisch aktiver (r)- oder (s)-beta -aminosäureester, und optisch aktive (s)- oder (r)-2-alkoxyethylester von beta- aminosäuren. - Google Patents
Verfahren zur herstellung optisch aktiver (s)- oder (r)-beta -aminosäuren und optisch aktiver (r)- oder (s)-beta -aminosäureester, und optisch aktive (s)- oder (r)-2-alkoxyethylester von beta- aminosäuren.Info
- Publication number
- ATE499449T1 ATE499449T1 AT05793727T AT05793727T ATE499449T1 AT E499449 T1 ATE499449 T1 AT E499449T1 AT 05793727 T AT05793727 T AT 05793727T AT 05793727 T AT05793727 T AT 05793727T AT E499449 T1 ATE499449 T1 AT E499449T1
- Authority
- AT
- Austria
- Prior art keywords
- optically active
- beta
- amino acids
- amino acid
- group
- Prior art date
Links
- 150000002148 esters Chemical class 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 150000001576 beta-amino acids Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- GOJUJUVQIVIZAV-UHFFFAOYSA-N 2-amino-4,6-dichloropyrimidine-5-carbaldehyde Chemical group NC1=NC(Cl)=C(C=O)C(Cl)=N1 GOJUJUVQIVIZAV-UHFFFAOYSA-N 0.000 abstract 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
- C12P13/222—Phenylalanine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004296080 | 2004-10-08 | ||
| PCT/JP2005/018699 WO2006038698A1 (ja) | 2004-10-08 | 2005-10-11 | 光学活性（Ｓ又はＲ）－β－アミノ酸及び光学活性（Ｒ又はＳ）－β－アミノ酸エステルの製造方法、並びにβ－アミノ酸２－アルコキシエチルエステル及び光学活性（Ｓ又はＲ）－β－アミノ酸２－アルコキシエチルエステル |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE499449T1 true ATE499449T1 (de) | 2011-03-15 |
Family
ID=36142768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05793727T ATE499449T1 (de) | 2004-10-08 | 2005-10-11 | Verfahren zur herstellung optisch aktiver (s)- oder (r)-beta -aminosäuren und optisch aktiver (r)- oder (s)-beta -aminosäureester, und optisch aktive (s)- oder (r)-2-alkoxyethylester von beta- aminosäuren. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7915019B2 (de) |
| EP (1) | EP1840218B1 (de) |
| JP (1) | JP4893308B2 (de) |
| CN (2) | CN102994606A (de) |
| AT (1) | ATE499449T1 (de) |
| CA (1) | CA2583322C (de) |
| DE (1) | DE602005026577D1 (de) |
| ES (1) | ES2359253T3 (de) |
| WO (1) | WO2006038698A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1942193A4 (de) * | 2005-08-25 | 2010-10-27 | Ube Industries | VERFAHREN ZUR HERSTELLUNG OPTISCH AKTIVER (S ODER R)-a- AMINOSÄURE ODER EINES OPTISCH AKTIVEN (S ODER R) -a-AMINOSÄUREESTERS |
| WO2008072764A1 (ja) * | 2006-12-15 | 2008-06-19 | Ube Industries, Ltd. | 光学活性（ｒ又はｓ）－ピペリジン－３－カルボン酸化合物及び光学活性（ｓ又はｒ）－ピペリジン－３－カルボン酸アルキルエステル化合物の製造方法 |
| DE102008013500A1 (de) | 2008-03-10 | 2009-09-17 | Evonik Degussa Gmbh | Neue chirale Selektoren und stationäre Phasen zur Trennung von Enantiomerengemischen |
| CN106191147B (zh) * | 2016-07-08 | 2020-03-27 | 凯莱英医药集团（天津）股份有限公司 | 手性β-氨基酸的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06113885A (ja) * | 1992-09-29 | 1994-04-26 | Nard Inst Ltd | ３−ヒドロキシ酪酸および３−ヒドロキシ酪酸エステルの製法 |
| US5350572A (en) | 1993-02-18 | 1994-09-27 | Shiseido Co., Ltd. | Permanent waving composition |
| JPH1014593A (ja) * | 1996-06-28 | 1998-01-20 | Ichikawa Gosei Kagaku Kk | 光学活性なトランス−２−ブロモインダン−１−オールの製造方法 |
| DE10220739A1 (de) * | 2002-05-08 | 2003-11-27 | Degussa | Verfahren zur enzymatischen Herstellung enantiomerenangereicherter ß-Amionsäuren |
| DE10220740A1 (de) * | 2002-05-08 | 2003-11-27 | Degussa | Verfahren zur enzymatischen Herstellung enantiomerenangereicherter beta-Aminosäuren |
| US6869781B2 (en) | 2002-05-08 | 2005-03-22 | Degussa Ag | Process for the enzymatic preparation of enantiomer-enriched β-amino acids |
| EP1621529A4 (de) * | 2003-03-17 | 2007-10-17 | Ube Industries | 3-amino-3-arylpropionsäure-n-alkylester, verfahren zu deren herstellung und verfahren zur herstellung von optisch aktiven 3-amino-3-arylpropionsäuren und estern der enantiomere davon |
-
2005
- 2005-10-11 CN CN2012102779355A patent/CN102994606A/zh active Pending
- 2005-10-11 AT AT05793727T patent/ATE499449T1/de active
- 2005-10-11 WO PCT/JP2005/018699 patent/WO2006038698A1/ja not_active Ceased
- 2005-10-11 CA CA2583322A patent/CA2583322C/en not_active Expired - Fee Related
- 2005-10-11 DE DE602005026577T patent/DE602005026577D1/de not_active Expired - Lifetime
- 2005-10-11 ES ES05793727T patent/ES2359253T3/es not_active Expired - Lifetime
- 2005-10-11 US US11/664,878 patent/US7915019B2/en not_active Expired - Fee Related
- 2005-10-11 CN CN200580034133.XA patent/CN101040053B/zh not_active Expired - Fee Related
- 2005-10-11 EP EP05793727A patent/EP1840218B1/de not_active Expired - Lifetime
- 2005-10-11 JP JP2006539349A patent/JP4893308B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN102994606A (zh) | 2013-03-27 |
| US7915019B2 (en) | 2011-03-29 |
| DE602005026577D1 (de) | 2011-04-07 |
| CA2583322C (en) | 2014-02-25 |
| JP4893308B2 (ja) | 2012-03-07 |
| ES2359253T3 (es) | 2011-05-19 |
| WO2006038698A1 (ja) | 2006-04-13 |
| CN101040053A (zh) | 2007-09-19 |
| EP1840218A1 (de) | 2007-10-03 |
| CN101040053B (zh) | 2013-04-24 |
| JPWO2006038698A1 (ja) | 2008-05-15 |
| EP1840218A4 (de) | 2009-11-11 |
| EP1840218B1 (de) | 2011-02-23 |
| CA2583322A1 (en) | 2006-04-13 |
| US20080038785A1 (en) | 2008-02-14 |
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| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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