ATE520687T1 - 3-amino-6-(1-amino-ethyl)-tetrahydropyranderiva e - Google Patents

3-amino-6-(1-amino-ethyl)-tetrahydropyranderiva e

Info

Publication number
ATE520687T1
ATE520687T1 AT08763320T AT08763320T ATE520687T1 AT E520687 T1 ATE520687 T1 AT E520687T1 AT 08763320 T AT08763320 T AT 08763320T AT 08763320 T AT08763320 T AT 08763320T AT E520687 T1 ATE520687 T1 AT E520687T1
Authority
AT
Austria
Prior art keywords
amino
tetrahydropyranderiva
ethyl
Prior art date
Application number
AT08763320T
Other languages
English (en)
Inventor
Christian Hubschwerlen
Georg Rueedi
Jean-Philippe Surivet
Acklin Cornelia Zumbrunn
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Application granted granted Critical
Publication of ATE520687T1 publication Critical patent/ATE520687T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT08763320T 2007-06-15 2008-06-13 3-amino-6-(1-amino-ethyl)-tetrahydropyranderiva e ATE520687T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2007052301 2007-06-15
PCT/IB2008/052333 WO2008152603A1 (en) 2007-06-15 2008-06-13 3-amino-6-(1-amino-ethyl)-tetrahydropyran derivatives

Publications (1)

Publication Number Publication Date
ATE520687T1 true ATE520687T1 (de) 2011-09-15

Family

ID=39772866

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08763320T ATE520687T1 (de) 2007-06-15 2008-06-13 3-amino-6-(1-amino-ethyl)-tetrahydropyranderiva e

Country Status (15)

Country Link
US (1) US8193179B2 (de)
EP (1) EP2167494B1 (de)
JP (1) JP5274553B2 (de)
KR (1) KR101538814B1 (de)
CN (1) CN101711243B (de)
AR (1) AR067008A1 (de)
AT (1) ATE520687T1 (de)
AU (1) AU2008263397B2 (de)
BR (1) BRPI0812942B1 (de)
CA (1) CA2689102C (de)
ES (1) ES2370123T3 (de)
MX (1) MX2009013254A (de)
PL (1) PL2167494T3 (de)
TW (1) TWI414290B (de)
WO (1) WO2008152603A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2411930T3 (es) 2008-02-20 2013-07-09 Actelion Pharmaceuticals Ltd. Compuestos antibióticos azatricíclicos
WO2009147616A1 (en) * 2008-06-03 2009-12-10 Actelion Pharmaceuticals Ltd [4-(1-amino-ethyl) -cyclohexyl] -methyl-amine and [6-(1-amino-ethyl) -tetrahydro- pyran-3-yl] -methyl-amine derivatives as antibacterials
KR101294962B1 (ko) 2008-10-07 2013-08-12 액테리온 파마슈티칼 리미티드 트리사이클 옥사졸리디논 항생제 화합물
CN102232078B (zh) * 2008-12-12 2014-07-16 埃科特莱茵药品有限公司 5-氨基-2-(1-羟基-乙基)-四氢吡喃衍生物
WO2012164498A1 (en) 2011-05-31 2012-12-06 Actelion Pharmaceuticals Ltd New synthetic intermediates for manufacturing antibiotics
AU2012275499A1 (en) * 2011-06-27 2013-12-19 Kyorin Pharmaceutical Co., Ltd. Bridged bicyclic compounds for the treatment of bacterial infections
CN106083787B (zh) * 2016-06-21 2018-05-04 济南川成医药科技开发有限公司 一种4-(2-氨乙基)四氢吡喃的合成方法
WO2018026877A1 (en) 2016-08-05 2018-02-08 Calitor Sciences, Llc Process for preparing substituted quinolin-4-ol compounds
TW201833120A (zh) 2017-02-17 2018-09-16 瑞士商愛杜西亞製藥有限公司 芳基噁唑啶酮抗生素化合物
CR20200054A (es) 2017-08-09 2020-03-21 Denali Therapeutics Inc Compuestos, composiciones y métodos
HUE062446T2 (hu) 2017-09-01 2023-11-28 Denali Therapeutics Inc Vegyületek, készítmények és eljárások
EP3923935A4 (de) 2019-02-13 2022-10-26 Denali Therapeutics Inc. Verbindungen, zusammensetzungen und verfahren
MA54959A (fr) 2019-02-13 2021-12-22 Denali Therapeutics Inc Composés, compositions et procédés
GB201904469D0 (en) 2019-03-29 2019-05-15 Givaudan Sa Cosmetic composition

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2816618B1 (fr) 2000-11-15 2002-12-27 Aventis Pharma Sa Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent
EP1551829B1 (de) * 2002-10-10 2010-04-07 Morphochem Aktiengesellschaft Für Kombinatorische Chemie Neue verbindungen mit antibakterieller aktivität
JP2008507543A (ja) * 2004-07-22 2008-03-13 グラクソ　グループ　リミテッド 抗細菌剤
DE102004041163A1 (de) * 2004-08-25 2006-03-02 Morphochem Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
JP4887297B2 (ja) * 2004-09-24 2012-02-29 アクテリオン ファーマシューティカルズ リミテッド 新規二環式抗生物質
WO2006046552A1 (ja) 2004-10-27 2006-05-04 Toyama Chemical Co., Ltd. 新規な含窒素複素環化合物およびその塩
WO2006125974A1 (en) * 2005-05-24 2006-11-30 Astrazeneca Ab Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity
CN101374831B (zh) * 2006-01-26 2011-04-27 埃科特莱茵药品有限公司 四氢吡喃抗生素
EP1996579A2 (de) * 2006-03-10 2008-12-03 Actelion Pharmaceuticals Ltd. Antibiotische verbindungen

Also Published As

Publication number Publication date
US8193179B2 (en) 2012-06-05
WO2008152603A1 (en) 2008-12-18
TW200906416A (en) 2009-02-16
CA2689102C (en) 2016-07-26
EP2167494B1 (de) 2011-08-17
KR20100023031A (ko) 2010-03-03
AU2008263397A1 (en) 2008-12-18
CN101711243A (zh) 2010-05-19
RU2010101003A (ru) 2011-07-20
CA2689102A1 (en) 2008-12-18
AU2008263397B2 (en) 2013-12-05
EP2167494A1 (de) 2010-03-31
AR067008A1 (es) 2009-09-30
ES2370123T3 (es) 2011-12-12
PL2167494T3 (pl) 2012-01-31
BRPI0812942B1 (pt) 2018-11-21
BRPI0812942A2 (pt) 2014-12-16
CN101711243B (zh) 2013-01-09
US20100179135A1 (en) 2010-07-15
BRPI0812942A8 (pt) 2018-05-02
KR101538814B1 (ko) 2015-07-22
TWI414290B (zh) 2013-11-11
JP2010529983A (ja) 2010-09-02
JP5274553B2 (ja) 2013-08-28
MX2009013254A (es) 2010-01-25

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