ATE536173T1 - Formulierungen mit modifizierter freisetzung von mindestens einer form von tramadol - Google Patents

Formulierungen mit modifizierter freisetzung von mindestens einer form von tramadol

Info

Publication number
ATE536173T1
ATE536173T1 AT03743147T AT03743147T ATE536173T1 AT E536173 T1 ATE536173 T1 AT E536173T1 AT 03743147 T AT03743147 T AT 03743147T AT 03743147 T AT03743147 T AT 03743147T AT E536173 T1 ATE536173 T1 AT E536173T1
Authority
AT
Austria
Prior art keywords
tramadol
release formulations
modified release
polyglycol
melting point
Prior art date
Application number
AT03743147T
Other languages
English (en)
Inventor
Pawan Seth
Paul Maes
Original Assignee
Biovail Lab Int Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27765948&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE536173(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biovail Lab Int Srl filed Critical Biovail Lab Int Srl
Application granted granted Critical
Publication of ATE536173T1 publication Critical patent/ATE536173T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Paints Or Removers (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT03743147T 2002-02-21 2003-02-21 Formulierungen mit modifizierter freisetzung von mindestens einer form von tramadol ATE536173T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35785102P 2002-02-21 2002-02-21
PCT/US2003/004866 WO2003072025A2 (en) 2002-02-21 2003-02-21 Modified release formulations of at least one form of tramadol

Publications (1)

Publication Number Publication Date
ATE536173T1 true ATE536173T1 (de) 2011-12-15

Family

ID=27765948

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03743147T ATE536173T1 (de) 2002-02-21 2003-02-21 Formulierungen mit modifizierter freisetzung von mindestens einer form von tramadol

Country Status (15)

Country Link
US (4) US7780987B2 (de)
EP (2) EP1476138B8 (de)
JP (3) JP5069395B2 (de)
AT (1) ATE536173T1 (de)
AU (2) AU2003211146B2 (de)
CA (2) CA2476496C (de)
CY (1) CY1112517T1 (de)
DK (1) DK1476138T3 (de)
ES (2) ES2377729T3 (de)
MX (2) MXPA04008100A (de)
NO (1) NO20043913L (de)
NZ (2) NZ535455A (de)
PT (1) PT1476138E (de)
SI (1) SI1476138T1 (de)
WO (2) WO2003072025A2 (de)

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NO20043913L (no) 2004-11-16
EP1476139A1 (de) 2004-11-17
SI1476138T1 (sl) 2012-07-31
CA2476496A1 (en) 2003-09-04
CA2476201C (en) 2009-09-01
JP2010155864A (ja) 2010-07-15
JP5069395B2 (ja) 2012-11-07
EP1476138B1 (de) 2011-12-07
NZ535455A (en) 2009-08-28
US20150030675A1 (en) 2015-01-29
AU2003211145B2 (en) 2007-07-12
CA2476496C (en) 2009-12-15
JP4704685B2 (ja) 2011-06-15
US7780987B2 (en) 2010-08-24
EP1476138A2 (de) 2004-11-17
EP1476138A4 (de) 2008-05-07
WO2003072089A1 (en) 2003-09-04
JP2005526047A (ja) 2005-09-02
EP1476139A4 (de) 2007-12-26
US20040037883A1 (en) 2004-02-26
AU2003211146B2 (en) 2007-07-19
CA2476201A1 (en) 2003-09-04
US20130245154A1 (en) 2013-09-19
WO2003072025A2 (en) 2003-09-04
MXPA04008164A (es) 2005-05-17
AU2003211145A1 (en) 2003-09-09
MXPA04008100A (es) 2005-06-17
PT1476138E (pt) 2012-02-14
NZ535456A (en) 2006-08-31
ES2627842T3 (es) 2017-07-31
ES2377729T3 (es) 2012-03-30
WO2003072025A3 (en) 2003-11-06
EP1476138B8 (de) 2012-03-07
AU2003211146A1 (en) 2003-09-09
JP2005526043A (ja) 2005-09-02
EP1476139B1 (de) 2017-05-17
CY1112517T1 (el) 2015-12-09
DK1476138T3 (da) 2012-02-20

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