ATE541569T1 - Verfahren zur isolation von phenolischen verbindungen - Google Patents
Verfahren zur isolation von phenolischen verbindungenInfo
- Publication number
- ATE541569T1 ATE541569T1 AT02753411T AT02753411T ATE541569T1 AT E541569 T1 ATE541569 T1 AT E541569T1 AT 02753411 T AT02753411 T AT 02753411T AT 02753411 T AT02753411 T AT 02753411T AT E541569 T1 ATE541569 T1 AT E541569T1
- Authority
- AT
- Austria
- Prior art keywords
- phenolic compounds
- aqueous
- aqueous phase
- extract
- isolation
- Prior art date
Links
- 150000002989 phenols Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 238000002955 isolation Methods 0.000 title 1
- 239000008346 aqueous phase Substances 0.000 abstract 4
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 3
- 239000000419 plant extract Substances 0.000 abstract 3
- 239000000284 extract Substances 0.000 abstract 2
- 239000006286 aqueous extract Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 abstract 1
- 150000002515 isoflavone derivatives Chemical class 0.000 abstract 1
- -1 isoflavones Chemical class 0.000 abstract 1
- 235000008696 isoflavones Nutrition 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Botany (AREA)
- General Health & Medical Sciences (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30753001P | 2001-07-24 | 2001-07-24 | |
| PCT/US2002/023555 WO2003010116A2 (en) | 2001-07-24 | 2002-07-23 | Process for isolating phenolic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE541569T1 true ATE541569T1 (de) | 2012-02-15 |
Family
ID=23190150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02753411T ATE541569T1 (de) | 2001-07-24 | 2002-07-23 | Verfahren zur isolation von phenolischen verbindungen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7015339B2 (de) |
| EP (1) | EP1420779B1 (de) |
| JP (1) | JP4475947B2 (de) |
| CN (1) | CN1556699B (de) |
| AT (1) | ATE541569T1 (de) |
| AU (1) | AU2002313702A1 (de) |
| CA (1) | CA2454636A1 (de) |
| WO (1) | WO2003010116A2 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040131749A1 (en) * | 2002-08-29 | 2004-07-08 | Archer-Daniels-Midland Company | Phytochemicals from edible bean process streams |
| AU2003298659A1 (en) | 2002-11-15 | 2004-06-15 | Cargill, Incorporated | Soluble isoflavone compositions |
| CN1901814A (zh) * | 2003-12-12 | 2007-01-24 | 天然香料公司 | 豆子胚芽提取物 |
| WO2005077930A1 (en) * | 2004-02-09 | 2005-08-25 | Cargill, Incorporated | Phenolic compound purification |
| WO2005077929A1 (en) * | 2004-02-09 | 2005-08-25 | Cargill, Incorporated | Phenolic compound purification |
| AU2005249147B2 (en) | 2004-06-04 | 2011-03-24 | Poly Gain Pte Ltd | Natural sweetener |
| WO2006094450A1 (en) * | 2005-03-07 | 2006-09-14 | Jumpsun Bio-Medicine (Shanghai) Co., Ltd. | Medicaments and food for treatment or prevention of obesity and/or diabetes containing cicer arietinum extract |
| JP5775656B2 (ja) | 2005-06-03 | 2015-09-09 | ホリズン サイエンス ピーティーワイ リミテッド | ボディマス再分布性を有する物質 |
| MY147363A (en) * | 2005-09-20 | 2012-11-30 | Nestec Sa | Water dispersible composition and method for preparing same |
| US20070269541A1 (en) * | 2006-05-19 | 2007-11-22 | Peter Rohdewald | Method and compositions for relieving menopausal and perimenopausal symptoms |
| JP3944864B1 (ja) * | 2006-07-31 | 2007-07-18 | 株式会社J−オイルミルズ | メタボリックシンドロームの予防および改善用組成物 |
| US20080044861A1 (en) * | 2006-08-15 | 2008-02-21 | Fermalogic, Inc. | Methods for Recovering Isoflavones from Fermentation Processes |
| MX2009002413A (es) * | 2006-09-19 | 2009-03-20 | Horizon Science Pty Ltd | Extractos derivados de la caña de azucar y un proceso para su manufactura. |
| US9005444B2 (en) * | 2008-05-13 | 2015-04-14 | Cargill, Incorporated | Separation of rebaudioside A from stevia glycosides using chromatography |
| CN104286779B (zh) * | 2009-06-16 | 2018-11-27 | 浙江绿世界制药有限公司 | 含有莱苞迪甙d的组合物及其应用 |
| US20110111115A1 (en) * | 2009-11-06 | 2011-05-12 | Jingang Shi | Rebaudioside a polymorphs and methods to prepare them |
| US9578895B2 (en) | 2010-08-23 | 2017-02-28 | Epc (Beijing) Natural Products Co., Ltd. | Rebaudioside A and stevioside compositions |
| WO2012106761A1 (en) | 2011-02-08 | 2012-08-16 | Horizon Science Pty Ltd | Sugar extracts |
| US9795156B2 (en) | 2011-03-17 | 2017-10-24 | E.P.C (Beijing) Plant Pharmaceutical Technology Co., Ltd | Rebaudioside B and derivatives |
| MY171216A (en) | 2012-08-28 | 2019-10-02 | The Product Makers Australia Pty Ltd | Extraction method |
| US9777106B2 (en) * | 2013-03-14 | 2017-10-03 | Case Western Reserve University | Bisphenol polymer precursor replacements |
| MY186191A (en) * | 2013-06-28 | 2021-06-30 | Malaysian Palm Oil Board | Isolation of novel bioactive compound obtained from oil palm base materials |
| WO2015021512A1 (en) | 2013-08-16 | 2015-02-19 | Horizon Science Pty Ltd | Sugar cane derived extracts and methods of treatment |
| US10264811B2 (en) | 2014-05-19 | 2019-04-23 | Epc Natural Products Co., Ltd. | Stevia sweetener with improved solubility |
| US10357052B2 (en) | 2014-06-16 | 2019-07-23 | Sweet Green Fields USA LLC | Rebaudioside A and stevioside with improved solubilities |
| US10485256B2 (en) | 2014-06-20 | 2019-11-26 | Sweet Green Fields International Co., Limited | Stevia sweetener with improved solubility with a cyclodextrin |
| CN110183541B (zh) * | 2019-04-23 | 2021-07-20 | 湖南华诚生物资源股份有限公司 | 红车轴草多糖及总异黄酮的制备方法 |
| CN113387988A (zh) * | 2021-05-12 | 2021-09-14 | 安徽工程大学 | 一种白扁豆花黄酮类化合物分离制备方法及用途 |
| CN118931767B (zh) * | 2024-07-24 | 2025-03-25 | 内蒙古医科大学附属医院(内蒙古自治区心血管研究所) | 一株纹带棒状杆菌nmgcs43及其应用 |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2952674A (en) * | 1958-08-08 | 1960-09-13 | Us Vitamin Corp | Method for the selective extraction of water soluble complex mixtures of biologically active flavonoid substances |
| BE616786A (fr) | 1961-04-26 | 1962-08-16 | Spofa Vereinigte Pharma Werke | Procédé de préparation d'une substance efficace contre les inflammations |
| US4218489A (en) | 1977-06-08 | 1980-08-19 | Z-L Limited Partnership | Antioxidants, antioxidant compositions and methods of preparing and using same |
| US4264509A (en) | 1977-06-08 | 1981-04-28 | Z-L Limited Partnership | Isoflavones and related compounds, methods of preparing and using and antioxidant compositions containing same |
| US4157984A (en) | 1977-06-08 | 1979-06-12 | Z-L Limited | Antioxidants, antioxidant compositions and methods of preparing and using same |
| US4232122A (en) | 1979-01-17 | 1980-11-04 | Z-L Limited Partnership | Antioxidants, antioxidant compositions and methods of preparing and using same |
| US4390559A (en) | 1979-04-11 | 1983-06-28 | Z-L Limited Partnership | Isoflavones and related compounds, methods of preparing and using and antioxidant compositions containing same |
| US4366248A (en) | 1979-04-11 | 1982-12-28 | Z-L Limited Partnership | Fermentation method of preparing antioxidants |
| US4366082A (en) | 1979-04-11 | 1982-12-28 | Z-L Limited Partnership | Isoflavones and related compounds, methods of preparing and using and antioxidant compositions containing same |
| JPS5933232A (ja) | 1982-08-19 | 1984-02-23 | Tokiwa Kanpou Seiyaku:Kk | マメ科植物からサポニン類およびフラボン類の分離方法 |
| JPS62126186A (ja) | 1985-11-28 | 1987-06-08 | Tsumura Juntendo Inc | イソフラボン誘導体含有溶液の製造方法 |
| CH679584A5 (de) | 1989-11-10 | 1992-03-13 | Nestle Sa | |
| JPH0436242A (ja) | 1990-05-30 | 1992-02-06 | Fuji Oil Co Ltd | 大豆サポニンの製造法 |
| JPH0645634B2 (ja) | 1991-02-21 | 1994-06-15 | 阿保 定吉 | 大豆イソフラボン配糖体 |
| US5244887A (en) | 1992-02-14 | 1993-09-14 | Straub Carl D | Stanols to reduce cholesterol absorption from foods and methods of preparation and use thereof |
| JPH06287554A (ja) | 1993-04-01 | 1994-10-11 | Aomori Pref Gov | 大豆粕叉はおからからの抗酸化性物質の製造方法 |
| JP2972494B2 (ja) * | 1993-06-30 | 1999-11-08 | 日本電気株式会社 | 半導体装置 |
| CA2173743A1 (en) | 1993-10-12 | 1995-04-20 | Jerome L. Shen | An aglucone isoflavone enriched vegetable protein extract and isolate and process for producing |
| US6140469A (en) | 1993-10-12 | 2000-10-31 | Protein Technologies International, Inc. | Protein isolate having an increased level of isoflavone compounds and process for producing the same |
| US5679806A (en) | 1995-02-24 | 1997-10-21 | Hauser, Inc. | Process for the isolation and purification of isoflavones |
| US5705618A (en) | 1995-03-31 | 1998-01-06 | Agriculture And Agri-Food Canada | Process for extracting lignans from flaxseed |
| JPH09312399A (ja) * | 1995-07-14 | 1997-12-02 | Seiko Instr Inc | 半導体装置とその製造方法 |
| US5968516A (en) | 1995-10-03 | 1999-10-19 | Liu; Yaguang | Soybean drug and new method of extracting soybean saponins |
| CN1881062B (zh) * | 1995-10-03 | 2013-11-20 | 精工爱普生株式会社 | 有源矩阵基板的制造方法和薄膜元件的制造方法 |
| US5936069A (en) | 1995-12-06 | 1999-08-10 | Iowa State University Research Foundation | Process for producing improved soy protein concentrate from genetically-modified soybeans |
| US5670632A (en) | 1996-01-18 | 1997-09-23 | Acds Technologies, Ltd. | Process for obtaining an isoflavone concentrate from a soybean extract |
| US6261565B1 (en) | 1996-03-13 | 2001-07-17 | Archer Daniels Midland Company | Method of preparing and using isoflavones |
| US6033714A (en) | 1996-03-13 | 2000-03-07 | Archer Daniels Midland Company | Process for production of isoflavone fractions from soy |
| US5702752A (en) | 1996-03-13 | 1997-12-30 | Archer Daniels Midland Company | Production of isoflavone enriched fractions from soy protein extracts |
| US6171638B1 (en) | 1996-03-13 | 2001-01-09 | Archer Daniels Midland Company | Production of isoflavone enriched fractions from soy protein extracts |
| US5821361A (en) | 1996-06-11 | 1998-10-13 | Protein Technologies International, Inc. | Recovery of isoflavones from soy molasses |
| US6040333A (en) * | 1996-07-30 | 2000-03-21 | Energetics, Inc. | Dietary supplements |
| JPH10316671A (ja) * | 1997-05-19 | 1998-12-02 | Kikkoman Corp | イソフラボン化合物の製造方法 |
| US5979921A (en) * | 1997-09-17 | 1999-11-09 | Burley Design Cooperative | Folding bicycle trailer |
| IN185730B (de) | 1998-02-19 | 2001-04-14 | Mcneil Ppc Inc | |
| JPH11346125A (ja) * | 1998-06-01 | 1999-12-14 | Sony Corp | Srpp回路 |
| US6013771A (en) | 1998-06-09 | 2000-01-11 | Protein Technologies International, Inc. | Isoflavone rich protein isolate and process for producing |
| ATE264093T1 (de) * | 1998-07-16 | 2004-04-15 | Aaron Tabor | Sojazubereitungen und deren verwendung zur gesundheitsförderung |
| JP2000262244A (ja) | 1999-03-18 | 2000-09-26 | Ajinomoto Co Inc | 大豆イソフラボン含有組成物とその製造方法 |
| KR100733056B1 (ko) * | 1999-12-17 | 2007-06-27 | 미츠노리 오노 | 수용성 콩류 추출물 |
| JP2004500374A (ja) | 2000-01-11 | 2004-01-08 | バイオレックス ヘルス リミッティッド | フラボノイドの抽出 |
| US6355816B1 (en) * | 2000-11-27 | 2002-03-12 | Wiley Organics, Inc. | Process for isolating saponins from soybean-derived materials |
-
2002
- 2002-07-23 EP EP02753411A patent/EP1420779B1/de not_active Expired - Lifetime
- 2002-07-23 WO PCT/US2002/023555 patent/WO2003010116A2/en not_active Ceased
- 2002-07-23 US US10/201,191 patent/US7015339B2/en not_active Expired - Fee Related
- 2002-07-23 JP JP2003515479A patent/JP4475947B2/ja not_active Expired - Lifetime
- 2002-07-23 AT AT02753411T patent/ATE541569T1/de active
- 2002-07-23 AU AU2002313702A patent/AU2002313702A1/en not_active Abandoned
- 2002-07-23 CN CN028184866A patent/CN1556699B/zh not_active Expired - Fee Related
- 2002-07-23 CA CA002454636A patent/CA2454636A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2454636A1 (en) | 2003-02-06 |
| EP1420779A2 (de) | 2004-05-26 |
| WO2003010116A2 (en) | 2003-02-06 |
| WO2003010116A3 (en) | 2003-07-03 |
| EP1420779B1 (de) | 2012-01-18 |
| JP2005504746A (ja) | 2005-02-17 |
| CN1556699B (zh) | 2010-05-12 |
| AU2002313702A1 (en) | 2003-02-17 |
| US20030139610A1 (en) | 2003-07-24 |
| CN1556699A (zh) | 2004-12-22 |
| JP4475947B2 (ja) | 2010-06-09 |
| EP1420779A4 (de) | 2005-03-16 |
| US7015339B2 (en) | 2006-03-21 |
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