ATE547100T1 - Leberfibroseinhibitor - Google Patents

Leberfibroseinhibitor

Info

Publication number
ATE547100T1
ATE547100T1 AT09157413T AT09157413T ATE547100T1 AT E547100 T1 ATE547100 T1 AT E547100T1 AT 09157413 T AT09157413 T AT 09157413T AT 09157413 T AT09157413 T AT 09157413T AT E547100 T1 ATE547100 T1 AT E547100T1
Authority
AT
Austria
Prior art keywords
carbon number
hepatic
liver fibrosis
fibrosis inhibitor
group
Prior art date
Application number
AT09157413T
Other languages
English (en)
Inventor
Naohisa Ishikawa
Tokutaro Miki
Hiroshi Nishikawa
Satoru Sugiyama
Original Assignee
Nippon Hypox Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Hypox Lab Inc filed Critical Nippon Hypox Lab Inc
Application granted granted Critical
Publication of ATE547100T1 publication Critical patent/ATE547100T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT09157413T 2008-04-14 2009-04-06 Leberfibroseinhibitor ATE547100T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2008105101A JP4630914B2 (ja) 2008-04-14 2008-04-14 肝線維化抑制剤

Publications (1)

Publication Number Publication Date
ATE547100T1 true ATE547100T1 (de) 2012-03-15

Family

ID=40910281

Family Applications (1)

Application Number Title Priority Date Filing Date
AT09157413T ATE547100T1 (de) 2008-04-14 2009-04-06 Leberfibroseinhibitor

Country Status (6)

Country Link
US (2) US20090270654A1 (de)
EP (1) EP2110127B1 (de)
JP (1) JP4630914B2 (de)
CN (1) CN101559049B (de)
AT (1) ATE547100T1 (de)
ES (1) ES2382522T3 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014092154A1 (ja) 2012-12-12 2014-06-19 株式会社ＰＲＩＳＭ Ｐｈａｒｍａ 肝線維症の予防または治療剤
WO2015093579A1 (ja) * 2013-12-20 2015-06-25 株式会社日本ハイポックス 糖尿病性腎症の予防又は治療剤
WO2016170704A1 (ja) * 2015-04-23 2016-10-27 株式会社日本ハイポックス 慢性呼吸器疾患治療剤及び心臓の線維化抑制組成物
JP7174408B2 (ja) 2016-02-10 2022-11-17 ウェイク・フォレスト・ユニヴァーシティ・ヘルス・サイエンシズ 肝線維症のモデル系ならびにその作製および使用方法
KR102013574B1 (ko) 2018-10-25 2019-08-23 주식회사 바이오톡스텍 하이드로퀴논 유도체를 포함하는 비만 또는 비알콜성 지방간염의 예방 또는 치료용 약학 조성물
WO2021029656A1 (ko) * 2019-08-14 2021-02-18 주식회사 바이오톡스텍 하이드로퀴논 유도체, 및 오베티콜릭산을 포함하는 비알콜성 지방간염의 예방 또는 치료용 약학조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2983317B2 (ja) 1991-03-28 1999-11-29 株式会社日本ハイポックス 新規ハイドロキノン誘導体
DE69217221T2 (de) * 1992-09-18 1997-05-15 Nippon Hypox Lab Inc Hydrochinonderivate und diese enthaltende Antioxydantien sowie Tumorinhibitoren
JPH06100441A (ja) 1992-09-22 1994-04-12 Nippon High Potsukusu:Kk ハイドロキノン誘導体含有発ガン阻止剤
JPH0867627A (ja) * 1994-08-31 1996-03-12 Nippon High Potsukusu:Kk 肝疾患治療用組成物
ES2146552B1 (es) 1998-11-24 2001-04-16 Inst Cientifico Tecnol Navarra Peptidos inhibidores de tgf/31
JP4749562B2 (ja) 2001-02-16 2011-08-17 株式会社日本ハイポックス ハイドロキノン誘導体および動脈硬化治療用組成物
JP2004352661A (ja) 2003-05-29 2004-12-16 Nippon Hypox Lab Inc 難治性炎症性疾患治療剤
JP3700854B2 (ja) 2003-07-24 2005-09-28 正 桂巻 線維化抑制剤
JP2005343889A (ja) 2004-05-06 2005-12-15 Taisho Pharmaceut Co Ltd イミダゾピリジン誘導体

Also Published As

Publication number Publication date
US20100184858A1 (en) 2010-07-22
US7847132B2 (en) 2010-12-07
HK1135619A1 (en) 2010-06-11
EP2110127A1 (de) 2009-10-21
US20090270654A1 (en) 2009-10-29
CN101559049B (zh) 2012-02-29
JP4630914B2 (ja) 2011-02-09
JP2009256226A (ja) 2009-11-05
ES2382522T3 (es) 2012-06-11
EP2110127B1 (de) 2012-02-29
CN101559049A (zh) 2009-10-21

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