ATE547388T1 - Verfahren zur verwendung von ä11cükohlenmonoxid zur markierenden synthese von 11c-markierten estern durch sensibilisierte photoinduzierte radikalische carbonylierung - Google Patents
Verfahren zur verwendung von ä11cükohlenmonoxid zur markierenden synthese von 11c-markierten estern durch sensibilisierte photoinduzierte radikalische carbonylierungInfo
- Publication number
- ATE547388T1 ATE547388T1 AT06744810T AT06744810T ATE547388T1 AT E547388 T1 ATE547388 T1 AT E547388T1 AT 06744810 T AT06744810 T AT 06744810T AT 06744810 T AT06744810 T AT 06744810T AT E547388 T1 ATE547388 T1 AT E547388T1
- Authority
- AT
- Austria
- Prior art keywords
- esters
- carbon monoxide
- labled
- labeling synthesis
- carbonylation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 title abstract 2
- 229910002091 carbon monoxide Inorganic materials 0.000 title abstract 2
- 230000006315 carbonylation Effects 0.000 title abstract 2
- 238000005810 carbonylation reaction Methods 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000002372 labelling Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 238000002600 positron emission tomography Methods 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000003504 photosensitizing agent Substances 0.000 abstract 1
- 239000012217 radiopharmaceutical Substances 0.000 abstract 1
- 229940121896 radiopharmaceutical Drugs 0.000 abstract 1
- 230000002799 radiopharmaceutical effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/10—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction with carbon monoxide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/36—Preparation of carboxylic acid esters by reaction with carbon monoxide or formates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C69/75—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of acids with a six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68846905P | 2005-06-08 | 2005-06-08 | |
| PCT/IB2006/001452 WO2006131803A2 (en) | 2005-06-08 | 2006-06-05 | Method for the use of [11c] carbon monoxide in labeling synthesis of 11c-labelled esters and acids by sensitized photo-induced free radical carbonylation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE547388T1 true ATE547388T1 (de) | 2012-03-15 |
Family
ID=37103323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06744810T ATE547388T1 (de) | 2005-06-08 | 2006-06-05 | Verfahren zur verwendung von ä11cükohlenmonoxid zur markierenden synthese von 11c-markierten estern durch sensibilisierte photoinduzierte radikalische carbonylierung |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20080226555A1 (de) |
| EP (1) | EP1896380B1 (de) |
| AT (1) | ATE547388T1 (de) |
| ES (1) | ES2380680T3 (de) |
| WO (1) | WO2006131803A2 (de) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU778834B2 (en) * | 1999-04-14 | 2004-12-23 | Molecular Insight Pharmaceuticals, Inc. | Fatty acid analogs for diagnosis of coronary artery disease |
| SE0102174D0 (sv) * | 2001-06-19 | 2001-06-19 | Tor Kihlberg | Method and apparatus for production and use of (11C) carbon monoxide in labeling synthesis |
| GB0116815D0 (en) * | 2001-07-10 | 2001-08-29 | Nycomed Amersham Plc | Improved chelator conjugates |
| ES2320897T3 (es) * | 2003-10-31 | 2009-05-29 | Ge Healthcare Limited | Procedimiento y aparato para el uso de monoxido de carbono (11c) en la sintesis de marcaje mediante carbonilacion fotoiniciada. |
| WO2006134424A2 (en) * | 2004-12-03 | 2006-12-21 | Ge Healthcare Limited | Method for the use of [11c] carbon monoxide in labeling synthesis of 11c-labelled acids by photo-induced free radical carbonylation |
-
2006
- 2006-06-05 ES ES06744810T patent/ES2380680T3/es active Active
- 2006-06-05 US US11/916,660 patent/US20080226555A1/en not_active Abandoned
- 2006-06-05 EP EP06744810A patent/EP1896380B1/de not_active Not-in-force
- 2006-06-05 WO PCT/IB2006/001452 patent/WO2006131803A2/en not_active Ceased
- 2006-06-05 AT AT06744810T patent/ATE547388T1/de active
-
2010
- 2010-03-02 US US12/715,657 patent/US20100158804A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1896380A2 (de) | 2008-03-12 |
| WO2006131803A2 (en) | 2006-12-14 |
| ES2380680T3 (es) | 2012-05-17 |
| US20080226555A1 (en) | 2008-09-18 |
| WO2006131803A3 (en) | 2007-03-01 |
| US20100158804A1 (en) | 2010-06-24 |
| EP1896380B1 (de) | 2012-02-29 |
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