ATE548020T1 - Kombinationen für orale zusammensetzungen, ihre herstellung und verwendung - Google Patents

Kombinationen für orale zusammensetzungen, ihre herstellung und verwendung

Info

Publication number: ATE548020T1
Authority: AT; Austria
Prior art keywords: combinations; preparation; oral compositions; composition; range
Prior art date: 2006-07-20

Application number

AT07766319T

Other languages

English (en)

Inventor

Ian Ripley

H Thomas

Original Assignee

Oraldent Ltd

Ricerfarma Srl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-07-20

Filing date

2007-07-20

Publication date

2012-03-15

2007-07-20 Application filed by Oraldent Ltd, Ricerfarma Srl filed Critical Oraldent Ltd

2012-03-15 Application granted granted Critical

2012-03-15 Publication of ATE548020T1 publication Critical patent/ATE548020T1/de

Links

239000000203 mixture Substances 0.000 title abstract 4
229920002385 Sodium hyaluronate Polymers 0.000 abstract 2
229940010747 sodium hyaluronate Drugs 0.000 abstract 2
YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
229940093797 bioflavonoids Drugs 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
235000013399 edible fruits Nutrition 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000011550 stock solution Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Birds (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Natural Medicines & Medicinal Plants (AREA)
Emergency Medicine (AREA)
Dermatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Oral & Maxillofacial Surgery (AREA)
Mycology (AREA)
Biotechnology (AREA)
Botany (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Nutrition Science (AREA)
Physiology (AREA)
Alternative & Traditional Medicine (AREA)
Medical Informatics (AREA)
Oil, Petroleum & Natural Gas (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Cosmetics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

AT07766319T 2006-07-20 2007-07-20 Kombinationen für orale zusammensetzungen, ihre herstellung und verwendung ATE548020T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0614353.1A GB0614353D0 (en)	2006-07-20	2006-07-20	Oral compositions, their preparation and use
PCT/GB2007/002756 WO2008009956A1 (en)	2006-07-20	2007-07-20	Combinations for oral compositions, their preparation and use

Publications (1)

Publication Number	Publication Date
ATE548020T1 true ATE548020T1 (de)	2012-03-15

Family

ID=36998354

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT07766321T ATE551988T1 (de)	2006-07-20	2007-07-20	Orale zusammensetzungen, ihre herstellung und verwendung
AT07766319T ATE548020T1 (de)	2006-07-20	2007-07-20	Kombinationen für orale zusammensetzungen, ihre herstellung und verwendung

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT07766321T ATE551988T1 (de)	2006-07-20	2007-07-20	Orale zusammensetzungen, ihre herstellung und verwendung

Country Status (9)

Country	Link
US (3)	US9532939B2 (de)
EP (2)	EP2043593B1 (de)
JP (3)	JP5508005B2 (de)
CN (2)	CN101495089B (de)
AT (2)	ATE551988T1 (de)
CA (2)	CA2658468C (de)
ES (2)	ES2385405T3 (de)
GB (2)	GB0614353D0 (de)
WO (2)	WO2008009958A1 (de)

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JP6118547B2 (ja) *	2012-12-10	2017-04-19	花王株式会社	口腔用組成物
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WO2015099754A1 (en) *	2013-12-27	2015-07-02	Colgate-Palmolive Company	Prebiotic oral care compositions containing carboxylic acids
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CN106446599A (zh) *	2015-08-11	2017-02-22	中国科学院青岛生物能源与过程研究所	一种筛选婴幼儿龋病的口腔致病性生物标记物的方法
RU2624502C2 (ru) *	2015-11-17	2017-07-04	Общество с ограниченной ответственностью "ДЖИ-Групп"	Лечебно-профилактический материал для стоматологии
CN107028839A (zh) *	2017-05-31	2017-08-11	易金阳	口腔护理组合物及其应用、牙膏组合物
GB201713362D0 (en) *	2017-08-21	2017-10-04	Givaudan Sa	Improvements in or relating to organic compounds
WO2019232031A1 (en)	2018-05-29	2019-12-05	Mary Kay Inc.	Topical compositions and methods
JP2020002019A (ja) *	2018-06-25	2020-01-09	ロート製薬株式会社	口腔用組成物
GB2578147A (en)	2018-10-18	2020-04-22	Oraldent Ltd	Bioflavonoid compositions and their use
GB2578146A (en)	2018-10-18	2020-04-22	Citrox Biosciences Ltd	Bioflavonoid compositions and their use for water purification and food preservation
CN109369805A (zh) *	2018-12-27	2019-02-22	广东工业大学	一种用于防治牙龈炎的卵黄抗体夹心含片及其制备方法
JP2020200245A (ja) *	2019-06-06	2020-12-17	ポッカサッポロフード＆ビバレッジ株式会社	口臭抑制用組成物
MX2021015131A (es)	2019-06-14	2022-01-24	Procter & Gamble	Composiciones para el cuidado bucal para usar y no enjuagar.
WO2020248239A1 (en)	2019-06-14	2020-12-17	The Procter & Gamble Company	Leave-on oral care compositions
WO2020248229A1 (en) *	2019-06-14	2020-12-17	The Procter & Gamble Company	Leave-on oral care compositions
BR112021024274A2 (pt)	2019-06-14	2022-01-11	Procter & Gamble	Composições para tratamento bucal sem enxágue
MX2021015129A (es)	2019-06-14	2022-01-24	Procter & Gamble	Composiciones para el cuidado bucal para usar y no enjuagar.
IT201900025483A1 (it) *	2019-12-24	2021-06-24	Adco S R L	Composizione per la disinfezione della cavità orale
WO2022157314A1 (en) *	2021-01-22	2022-07-28	Dsm Ip Assets B.V.	Hyaluronic acid for use on the skin
GB2605971A (en)	2021-04-19	2022-10-26	Citrox Biosciences Ltd	Nutritional supplement and uses
GB2605972A (en)	2021-04-19	2022-10-26	Citrox Biosciences Ltd	Nutritional supplements for amelioration of respiratory tract infections
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WO2023104843A1 (de)	2021-12-09	2023-06-15	Beiersdorf Ag	Topisch applizierbare zubereitung zur verbesserung des hautzustandes
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CN116785319B (zh) *	2023-06-21	2025-09-05	苏州大学	一种菌囊泡包被的核壳结构ZnO2-Fe3O4纳米复合材料、制备方法及其应用
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2006
- 2006-07-20 GB GBGB0614353.1A patent/GB0614353D0/en not_active Ceased
2007
- 2007-07-20 CA CA2658468A patent/CA2658468C/en active Active
- 2007-07-20 US US12/374,443 patent/US9532939B2/en active Active
- 2007-07-20 WO PCT/GB2007/002758 patent/WO2008009958A1/en not_active Ceased
- 2007-07-20 ES ES07766321T patent/ES2385405T3/es active Active
- 2007-07-20 EP EP07766321A patent/EP2043593B1/de not_active Not-in-force
- 2007-07-20 US US12/374,447 patent/US20100068157A1/en not_active Abandoned
- 2007-07-20 EP EP07766319A patent/EP2043592B1/de not_active Not-in-force
- 2007-07-20 JP JP2009520056A patent/JP5508005B2/ja not_active Expired - Fee Related
- 2007-07-20 CA CA2658710A patent/CA2658710C/en active Active
- 2007-07-20 ES ES07766319T patent/ES2384687T3/es active Active
- 2007-07-20 WO PCT/GB2007/002756 patent/WO2008009956A1/en not_active Ceased
- 2007-07-20 AT AT07766321T patent/ATE551988T1/de active
- 2007-07-20 CN CN200780027437.2A patent/CN101495089B/zh not_active Expired - Fee Related
- 2007-07-20 CN CN200780027438.7A patent/CN101495090B/zh not_active Expired - Fee Related
- 2007-07-20 AT AT07766319T patent/ATE548020T1/de active
- 2007-07-20 JP JP2009520055A patent/JP5452221B2/ja not_active Expired - Fee Related
- 2007-07-20 GB GB0714228A patent/GB2440440A/en not_active Withdrawn
2013
- 2013-12-27 JP JP2013270823A patent/JP5883428B2/ja not_active Expired - Fee Related
2016
- 2016-08-25 US US15/247,806 patent/US9987214B2/en active Active

Also Published As

Publication number	Publication date
CN101495089A (zh)	2009-07-29
CA2658710C (en)	2016-07-05
ES2384687T3 (es)	2012-07-11
US9987214B2 (en)	2018-06-05
CN101495090B (zh)	2015-04-22
US20160361346A1 (en)	2016-12-15
US9532939B2 (en)	2017-01-03
JP5883428B2 (ja)	2016-03-15
GB2440440A (en)	2008-01-30
CN101495090A (zh)	2009-07-29
JP2009544603A (ja)	2009-12-17
JP5452221B2 (ja)	2014-03-26
JP5508005B2 (ja)	2014-05-28
CN101495089B (zh)	2019-06-11
US20100068157A1 (en)	2010-03-18
GB0714228D0 (en)	2007-08-29
CA2658468C (en)	2017-05-23
WO2008009958A1 (en)	2008-01-24
CA2658468A1 (en)	2008-01-24
ATE551988T1 (de)	2012-04-15
GB0614353D0 (en)	2006-08-30
ES2385405T3 (es)	2012-07-24
CA2658710A1 (en)	2008-01-24
EP2043592B1 (de)	2012-03-07
JP2014074062A (ja)	2014-04-24
EP2043592A1 (de)	2009-04-08
EP2043593B1 (de)	2012-04-04
US20100055053A1 (en)	2010-03-04
JP2009544604A (ja)	2009-12-17
WO2008009956A1 (en)	2008-01-24
EP2043593A1 (de)	2009-04-08

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