EA201190306A1 - Улучшенная липидная композиция - Google Patents

Улучшенная липидная композиция

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Publication number
EA201190306A1
EA201190306A1 EA201190306A EA201190306A EA201190306A1 EA 201190306 A1 EA201190306 A1 EA 201190306A1 EA 201190306 A EA201190306 A EA 201190306A EA 201190306 A EA201190306 A EA 201190306A EA 201190306 A1 EA201190306 A1 EA 201190306A1
Authority
EA
Eurasian Patent Office
Prior art keywords
lipid composition
improved lipid
lipid
formula
improved
Prior art date
Application number
EA201190306A
Other languages
English (en)
Other versions
EA024960B1 (ru
Inventor
Акин Акинг
Джозеф Р. Доркин
Сяоцзюнь Цинь
Вильям Кентли
Мутиах Манохаран
Каллантоттатил Г. Раджив
Джаяпракаш К. Нараянаннаир
Мутусами Джаяраман
Цзяньсинь Чэнь
Стивен Энселл
Original Assignee
Элнилэм Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Элнилэм Фармасьютикалз, Инк. filed Critical Элнилэм Фармасьютикалз, Инк.
Publication of EA201190306A1 publication Critical patent/EA201190306A1/ru
Publication of EA024960B1 publication Critical patent/EA024960B1/ru

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    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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Abstract

Изобретение относится к катионному липиду формулы (1) улучшенной липидной композиции, содержащей катионный липид формулы I, и соответствующим способам применения. Также описаны нацеливающие липиды и специфичные липидные композиции, содержащие указанные нацеливающие липиды.
EA201190306A 2009-06-10 2010-06-10 Улучшенная липидная композиция EA024960B1 (ru)

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