ATE86854T1 - Sauerstoff- oder schwefelsubstituierte fettsaeureanaloga zur behandlung retroviraler infektionen. - Google Patents
Sauerstoff- oder schwefelsubstituierte fettsaeureanaloga zur behandlung retroviraler infektionen.Info
- Publication number
- ATE86854T1 ATE86854T1 AT90870135T AT90870135T ATE86854T1 AT E86854 T1 ATE86854 T1 AT E86854T1 AT 90870135 T AT90870135 T AT 90870135T AT 90870135 T AT90870135 T AT 90870135T AT E86854 T1 ATE86854 T1 AT E86854T1
- Authority
- AT
- Austria
- Prior art keywords
- fatty acid
- treatment
- oxygen
- retroviral infections
- acid analogs
- Prior art date
Links
- 150000004665 fatty acids Chemical class 0.000 title abstract 4
- 206010038997 Retroviral infections Diseases 0.000 title abstract 3
- 235000014113 dietary fatty acids Nutrition 0.000 title abstract 3
- 229930195729 fatty acid Natural products 0.000 title abstract 3
- 239000000194 fatty acid Substances 0.000 title abstract 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 title abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052760 oxygen Inorganic materials 0.000 title abstract 2
- 239000001301 oxygen Substances 0.000 title abstract 2
- 229910052717 sulfur Chemical group 0.000 title abstract 2
- 239000011593 sulfur Chemical group 0.000 title abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/60—Unsaturated compounds containing ether groups, groups, groups, or groups the non-carboxylic part of the ether being unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Emergency Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/402,094 US5073571A (en) | 1988-06-16 | 1989-09-01 | Method of inhibiting virus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE86854T1 true ATE86854T1 (de) | 1993-04-15 |
Family
ID=23590495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90870135T ATE86854T1 (de) | 1989-09-01 | 1990-08-31 | Sauerstoff- oder schwefelsubstituierte fettsaeureanaloga zur behandlung retroviraler infektionen. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5073571A (de) |
| EP (1) | EP0415902B1 (de) |
| JP (1) | JPH0714875B2 (de) |
| AT (1) | ATE86854T1 (de) |
| CA (1) | CA2024489A1 (de) |
| DE (1) | DE69001107T2 (de) |
| DK (1) | DK0415902T3 (de) |
| ES (1) | ES2055407T3 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0445097T3 (da) * | 1990-02-26 | 1996-09-16 | Univ Washington | Fremgangsmåde til N-myristoylering af protein |
| US5236955A (en) * | 1992-04-10 | 1993-08-17 | Washington University | Anti-fungal agent |
| US6602861B1 (en) * | 1992-04-16 | 2003-08-05 | Research Corporation Technologies, Inc. | Acylated phospholipid drugs |
| GB9212276D0 (en) * | 1992-06-10 | 1992-07-22 | Harper David R | Anti-viral agents |
| GB2267642B (en) * | 1992-06-10 | 1996-04-24 | British Tech Group | Anti-viral agents |
| US5463152A (en) * | 1994-12-08 | 1995-10-31 | E. I. Du Pont De Nemours And Company | Halofluorocarbon hydrogenolysis |
| US5599947A (en) * | 1993-01-14 | 1997-02-04 | G. D. Searle & Co. | Fatty acid analogs and prodrugs |
| US5859052A (en) * | 1993-01-14 | 1999-01-12 | G. D. Searle & Co. | Fatty acid analogs and prodrugs |
| DE10063111A1 (de) * | 2000-12-18 | 2002-06-20 | Bayer Ag | Replikationsassay zur Auffindung antiviraler Substanzen |
| US20120028335A1 (en) | 2010-07-28 | 2012-02-02 | Life Technologies Corporation | Anti-viral azide-containing compounds |
| US20130209550A1 (en) | 2010-07-28 | 2013-08-15 | Life Technologies Corporation | Anti-Viral Azide Containing Compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2262514A1 (en) * | 1974-03-01 | 1975-09-26 | Alary Josette | Reticulo-endothelial stimulating compsn. - contg. sodium oleate, sodium stearate and neutralised olive oil |
| US4513005A (en) * | 1981-06-18 | 1985-04-23 | Lilly Industries Limited | SRS-A antagonists |
| US4740588A (en) * | 1986-08-07 | 1988-04-26 | Washington University | Novel substrate peptides |
| US4709012A (en) * | 1986-08-07 | 1987-11-24 | Washington University | Novel inhibitor peptides |
-
1989
- 1989-09-01 US US07/402,094 patent/US5073571A/en not_active Expired - Fee Related
-
1990
- 1990-08-31 DE DE90870135T patent/DE69001107T2/de not_active Expired - Fee Related
- 1990-08-31 DK DK90870135.2T patent/DK0415902T3/da active
- 1990-08-31 ES ES90870135T patent/ES2055407T3/es not_active Expired - Lifetime
- 1990-08-31 EP EP90870135A patent/EP0415902B1/de not_active Expired - Lifetime
- 1990-08-31 JP JP2232269A patent/JPH0714875B2/ja not_active Expired - Lifetime
- 1990-08-31 AT AT90870135T patent/ATE86854T1/de not_active IP Right Cessation
- 1990-08-31 CA CA002024489A patent/CA2024489A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69001107D1 (de) | 1993-04-22 |
| EP0415902B1 (de) | 1993-03-17 |
| JPH03109322A (ja) | 1991-05-09 |
| JPH0714875B2 (ja) | 1995-02-22 |
| CA2024489A1 (en) | 1991-03-02 |
| DE69001107T2 (de) | 1993-10-07 |
| ES2055407T3 (es) | 1994-08-16 |
| DK0415902T3 (da) | 1993-04-19 |
| US5073571A (en) | 1991-12-17 |
| EP0415902A1 (de) | 1991-03-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |