ATE92926T1 - Heterocyclische verbindungen und ihre herstellung und anwendung. - Google Patents

Heterocyclische verbindungen und ihre herstellung und anwendung.

Info

Publication number
ATE92926T1
ATE92926T1 AT88301783T AT88301783T ATE92926T1 AT E92926 T1 ATE92926 T1 AT E92926T1 AT 88301783 T AT88301783 T AT 88301783T AT 88301783 T AT88301783 T AT 88301783T AT E92926 T1 ATE92926 T1 AT E92926T1
Authority
AT
Austria
Prior art keywords
alkyl
heterocyclic compounds
production
application
alkynyl
Prior art date
Application number
AT88301783T
Other languages
English (en)
Inventor
Frank Waetjen
Holger Claus Hansen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE92926T1 publication Critical patent/ATE92926T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Luminescent Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT88301783T 1987-03-18 1988-03-01 Heterocyclische verbindungen und ihre herstellung und anwendung. ATE92926T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK137487A DK155524C (da) 1987-03-18 1987-03-18 Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse
EP88301783A EP0283162B1 (de) 1987-03-18 1988-03-01 Heterocyclische Verbindungen und ihre Herstellung und Anwendung

Publications (1)

Publication Number Publication Date
ATE92926T1 true ATE92926T1 (de) 1993-08-15

Family

ID=8104158

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88301783T ATE92926T1 (de) 1987-03-18 1988-03-01 Heterocyclische verbindungen und ihre herstellung und anwendung.

Country Status (18)

Country Link
US (2) US4873244A (de)
EP (1) EP0283162B1 (de)
JP (1) JPS6463581A (de)
KR (1) KR960010455B1 (de)
AT (1) ATE92926T1 (de)
AU (1) AU607469B2 (de)
CA (1) CA1308712C (de)
DE (1) DE3883033T2 (de)
DK (1) DK155524C (de)
ES (1) ES2058251T3 (de)
FI (1) FI92700C (de)
IE (1) IE62320B1 (de)
IL (1) IL85295A (de)
NO (1) NO169340C (de)
NZ (1) NZ223777A (de)
PH (2) PH24076A (de)
PT (1) PT87013B (de)
ZA (1) ZA881140B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK160876C (da) * 1987-12-08 1991-10-14 Novo Nordisk As Imidazoquinoxalinforbindelser, fremgangsmaade til deres fremstilling, anvendelse af forbindelserne og farmaceutiske praeparater, hvori forbindelserne indgaar
IL90315A0 (en) * 1988-06-01 1989-12-15 Ferrosan As Imidazoquinoxaline compounds,their preparation and pharmaceutical compositions containing them
DK161148C (da) * 1988-06-14 1991-11-18 Novo Nordisk As Imidazoquinoxalinforbindelser, fremgangsmaade til fremstilling deraf samt farmaceutiske praeprater indeholdende forbindelserne
DK626288D0 (da) * 1988-11-10 1988-11-10 Ferrosan As Kemisk proces til fremstilling af imidazoquinoxaliner og mellemprodukter til brug i processen
DK588489D0 (da) * 1989-11-22 1989-11-22 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
DK588389D0 (da) * 1989-11-22 1989-11-22 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
FR2659329B1 (fr) * 1990-03-09 1994-06-03 Adir Nouveaux derives d'imidazo [1,2-c] quinazoline, leur procede de preparation et les compositions pharmaceutiques les renfermant.
DK151890D0 (da) * 1990-06-22 1990-06-22 Ferrosan As Heterocykliske forbindelser deres fremstilling og brug
DK204291D0 (da) * 1991-12-20 1991-12-20 Novo Nordisk As Heterocykliske forbindelser deres fremstilling og anvendelse
US5276028A (en) * 1990-06-22 1994-01-04 Nordisk A/S Imidazoquinoxaline compounds
US5371080A (en) * 1990-06-22 1994-12-06 Novo Nordisk A/S Imidazoquinazoline compounds and their use
WO1992004350A1 (en) * 1990-09-04 1992-03-19 The Upjohn Company Oxygenated quinoxalines
CA2110942A1 (en) * 1991-06-14 1992-12-23 Pharmacia & Upjohn Company Llc Imidazo¬1,5-a|quinoxalines
WO1993012113A1 (en) * 1991-12-17 1993-06-24 The Upjohn Company 3-SUBSTITUTED IMIDAZO (1,5-a) AND IMIDAZO (1,5-a)-TRIAZOLO (1,5-c) QUINOXALINES AND QUINAZOLINES WITH CNS ACTIVITY
JP3512110B2 (ja) * 1992-02-13 2004-03-29 ファルマシア・アンド・アップジョン・カンパニー ベンゾジアゼピン受容体結合剤として有用な４−オキソ−および４Ｈ−イミダゾ（５，１−ｃ）（１，４）ベンゾオキサジン類
WO1993017025A1 (en) * 1992-02-19 1993-09-02 The Upjohn Company 3-substituted imidazo(1,5-a)quinoxalines and quinazolines with cns activity
US5367077A (en) * 1992-04-08 1994-11-22 Neurogen Corporation Certain cycloalkyl and azacycloalkyl pyrrolopyridines; a new class of gaba rain receptor ligands
USRE35840E (en) * 1993-11-19 1998-07-07 Pharmacia & Upjohn Company Imidazo 1,5-a!quinolines for treatment of anxiety and sleep disorders
EP0743855A1 (de) * 1994-01-03 1996-11-27 Acea Pharmaceuticals, Inc. 8-Aza,6-Aza und 6,8-Diaza - 1,4 dihydrochinoxalin -2,3-dione und deren Verwendung als Glycin/NMDARezeptor Antagonisten
FR2799757B1 (fr) * 1999-10-15 2001-12-14 Adir Nouveaux derives polycycliques azaindoliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
HRP20030675A2 (en) * 2001-01-26 2004-08-31 Bristol Myers Squibb Co Imidazolyl derivatives as corticotropin relasing factor inhibitors
WO2017149469A1 (en) 2016-03-03 2017-09-08 Emcure Pharmaceuticals Limited Heterocyclic compounds useful as ido and/or tdo modulators

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4440929A (en) * 1981-07-16 1984-04-03 Usv Pharmaceutical Corporation Imidazoquinoxaline compounds
DK476885D0 (da) * 1985-10-17 1985-10-17 Ferrosan As Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
US4771051A (en) * 1985-05-17 1988-09-13 A/S Ferrosan 3-substituted-4,5-dihydro-5-oxo imidazoquinazolines, their preparation, and their use in treating benzodiazepin receptor-related ailments
DE3661197D1 (en) * 1985-05-17 1988-12-22 Ferrosan As Oxadiazolylimidazobenzodiazepines, process for their preparation and pharmaceutical compositions
DE3686723T2 (de) * 1985-10-17 1993-04-01 Novonordisk As Oxadiazolylacetonitrile, ihre herstellung und anwendung.
DK160876C (da) * 1987-12-08 1991-10-14 Novo Nordisk As Imidazoquinoxalinforbindelser, fremgangsmaade til deres fremstilling, anvendelse af forbindelserne og farmaceutiske praeparater, hvori forbindelserne indgaar
IL90315A0 (en) * 1988-06-01 1989-12-15 Ferrosan As Imidazoquinoxaline compounds,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
NO169340B (no) 1992-03-02
DK137487A (da) 1988-09-19
KR960010455B1 (ko) 1996-08-01
IE62320B1 (en) 1995-01-25
FI880815A0 (fi) 1988-02-22
PT87013A (pt) 1989-03-30
JPS6463581A (en) 1989-03-09
FI880815A7 (fi) 1988-09-19
AU1325988A (en) 1988-09-22
NO881191L (no) 1988-09-19
PH24076A (en) 1990-03-05
DE3883033T2 (de) 1993-12-16
US4902686A (en) 1990-02-20
IL85295A (en) 1991-12-12
PT87013B (pt) 1995-03-01
ES2058251T3 (es) 1994-11-01
KR880011157A (ko) 1988-10-26
DK137487D0 (da) 1987-03-18
EP0283162A3 (en) 1990-05-30
DK155524B (da) 1989-04-17
AU607469B2 (en) 1991-03-07
DE3883033D1 (de) 1993-09-16
EP0283162B1 (de) 1993-08-11
EP0283162A2 (de) 1988-09-21
DK155524C (da) 1989-09-11
NO881191D0 (no) 1988-03-17
US4873244A (en) 1989-10-10
IE880438L (en) 1988-09-18
FI92700B (fi) 1994-09-15
ZA881140B (en) 1988-08-15
NO169340C (no) 1992-06-10
PH24165A (en) 1990-03-22
FI92700C (fi) 1994-12-27
NZ223777A (en) 1989-09-27
CA1308712C (en) 1992-10-13

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee