ATE97000T1 - Zubereitung zur perkutanen anwendung. - Google Patents

Zubereitung zur perkutanen anwendung.

Info

Publication number: ATE97000T1
Authority: AT; Austria
Prior art keywords: ethyl; ester; pref; emedastine; esters
Prior art date: 1989-08-28

Application number

AT90912459T

Other languages

English (en)

Inventor

Hiroshi Nakagawa

Shoichi Harada

Original Assignee

Kanebo Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-28

Filing date

1990-08-23

Publication date

1993-11-15

1990-08-23 Application filed by Kanebo Ltd filed Critical Kanebo Ltd

1993-11-15 Application granted granted Critical

1993-11-15 Publication of ATE97000T1 publication Critical patent/ATE97000T1/de

Links

KBUZBQVCBVDWKX-UHFFFAOYSA-N emedastine Chemical compound N=1C2=CC=CC=C2N(CCOCC)C=1N1CCCN(C)CC1 KBUZBQVCBVDWKX-UHFFFAOYSA-N 0.000 abstract 4
150000002148 esters Chemical class 0.000 abstract 4
229960000325 emedastine Drugs 0.000 abstract 3
125000001931 aliphatic group Chemical group 0.000 abstract 2
-1 aliphatic monocarboxylic acids Chemical class 0.000 abstract 2
125000005907 alkyl ester group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
RGXWDWUGBIJHDO-UHFFFAOYSA-N ethyl decanoate Chemical compound CCCCCCCCCC(=O)OCC RGXWDWUGBIJHDO-UHFFFAOYSA-N 0.000 abstract 2
SHZIWNPUGXLXDT-UHFFFAOYSA-N ethyl hexanoate Chemical compound CCCCCC(=O)OCC SHZIWNPUGXLXDT-UHFFFAOYSA-N 0.000 abstract 2
MMXKVMNBHPAILY-UHFFFAOYSA-N ethyl laurate Chemical compound CCCCCCCCCCCC(=O)OCC MMXKVMNBHPAILY-UHFFFAOYSA-N 0.000 abstract 2
MMKRHZKQPFCLLS-UHFFFAOYSA-N ethyl myristate Chemical compound CCCCCCCCCCCCCC(=O)OCC MMKRHZKQPFCLLS-UHFFFAOYSA-N 0.000 abstract 2
YYZUSRORWSJGET-UHFFFAOYSA-N ethyl octanoate Chemical group CCCCCCCC(=O)OCC YYZUSRORWSJGET-UHFFFAOYSA-N 0.000 abstract 2
WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 abstract 1
QMMJWQMCMRUYTG-UHFFFAOYSA-N 1,2,4,5-tetrachloro-3-(trifluoromethyl)benzene Chemical compound FC(F)(F)C1=C(Cl)C(Cl)=CC(Cl)=C1Cl QMMJWQMCMRUYTG-UHFFFAOYSA-N 0.000 abstract 1
LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 abstract 1
HBTAOSGHCXUEKI-UHFFFAOYSA-N 4-chloro-n,n-dimethyl-3-nitrobenzenesulfonamide Chemical compound CN(C)S(=O)(=O)C1=CC=C(Cl)C([N+]([O-])=O)=C1 HBTAOSGHCXUEKI-UHFFFAOYSA-N 0.000 abstract 1
HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 abstract 1
QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 abstract 1
VIZORQUEIQEFRT-UHFFFAOYSA-N Diethyl adipate Chemical compound CCOC(=O)CCCCC(=O)OCC VIZORQUEIQEFRT-UHFFFAOYSA-N 0.000 abstract 1
LVGKNOAMLMIIKO-UHFFFAOYSA-N Elaidinsaeure-aethylester Natural products CCCCCCCCC=CCCCCCCCC(=O)OCC LVGKNOAMLMIIKO-UHFFFAOYSA-N 0.000 abstract 1
OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 abstract 1
239000005642 Oleic acid Substances 0.000 abstract 1
DHAZIUXMHRHVMP-UHFFFAOYSA-N butyl tetradecanoate Chemical compound CCCCCCCCCCCCCC(=O)OCCCC DHAZIUXMHRHVMP-UHFFFAOYSA-N 0.000 abstract 1
239000006071 cream Substances 0.000 abstract 1
PEUGOJXLBSIJQS-UHFFFAOYSA-N diethyl octanedioate Chemical compound CCOC(=O)CCCCCCC(=O)OCC PEUGOJXLBSIJQS-UHFFFAOYSA-N 0.000 abstract 1
229940031578 diisopropyl adipate Drugs 0.000 abstract 1
QYDYPVFESGNLHU-UHFFFAOYSA-N elaidic acid methyl ester Natural products CCCCCCCCC=CCCCCCCCC(=O)OC QYDYPVFESGNLHU-UHFFFAOYSA-N 0.000 abstract 1
239000000839 emulsion Substances 0.000 abstract 1
LVGKNOAMLMIIKO-QXMHVHEDSA-N ethyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC LVGKNOAMLMIIKO-QXMHVHEDSA-N 0.000 abstract 1
229940093471 ethyl oleate Drugs 0.000 abstract 1
239000000499 gel Substances 0.000 abstract 1
QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 abstract 1
XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 abstract 1
239000006210 lotion Substances 0.000 abstract 1
QYDYPVFESGNLHU-KHPPLWFESA-N methyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC QYDYPVFESGNLHU-KHPPLWFESA-N 0.000 abstract 1
229940073769 methyl oleate Drugs 0.000 abstract 1
150000002762 monocarboxylic acid derivatives Chemical class 0.000 abstract 1
WIBFFTLQMKKBLZ-SEYXRHQNSA-N n-butyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCCCC WIBFFTLQMKKBLZ-SEYXRHQNSA-N 0.000 abstract 1
KSCKTBJJRVPGKM-UHFFFAOYSA-N octan-1-olate;titanium(4+) Chemical compound [Ti+4].CCCCCCCC[O-].CCCCCCCC[O-].CCCCCCCC[O-].CCCCCCCC[O-] KSCKTBJJRVPGKM-UHFFFAOYSA-N 0.000 abstract 1
ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 abstract 1
239000007921 spray Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Dermatology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Pulmonology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT90912459T 1989-08-28 1990-08-23 Zubereitung zur perkutanen anwendung. ATE97000T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP1220788A JPH0383924A (ja)	1989-08-28	1989-08-28	経皮投与用組成物
PCT/JP1990/001073 WO1991003244A1 (fr)	1989-08-28	1990-08-23	Preparation destinee a l'administration percutanee

Publications (1)

Publication Number	Publication Date
ATE97000T1 true ATE97000T1 (de)	1993-11-15

Family

ID=16756579

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90912459T ATE97000T1 (de)	1989-08-28	1990-08-23	Zubereitung zur perkutanen anwendung.

Country Status (9)

Country	Link
US (1)	US5321022A (de)
EP (1)	EP0440811B1 (de)
JP (1)	JPH0383924A (de)
KR (1)	KR920700647A (de)
AT (1)	ATE97000T1 (de)
DE (1)	DE69004561T2 (de)
DK (1)	DK0440811T3 (de)
ES (1)	ES2062545T3 (de)
WO (1)	WO1991003244A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3527256B2 (ja) *	1992-12-09	2004-05-17	ロート製薬株式会社	抗アレルギー点眼剤
FR2727865B1 (fr) *	1994-12-08	1997-07-18	Esteve Labor Dr	Utilisation des derives de 2-(4-(azolybutyl)-piperazinyl- (methyl))-benzimidazole et analogues ainsi que de leurs sels, pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme
WO1996033722A1 (en) *	1995-04-27	1996-10-31	Kanebo, Ltd.	External preparation containing emedastine
IT1318705B1 (it) *	2000-09-22	2003-08-27	Gianluigi Ciocca	Medicamento transdermico ad alta penetrazione.
AUPS317302A0 (en) *	2002-06-25	2002-07-18	Drug Delivery Solutions Pty Ltd	Metastable pharmaceutical compositions
KR20100055542A (ko)	2002-06-25	2010-05-26	애크럭스 디디에스 피티와이 리미티드	비정질 약학적 조성물을 이용한 경피전달속도의 제어
ES2776146T3 (es)	2011-04-18	2020-07-29	Hisamitsu Pharmaceutical Co	Método para producir un parche adhesivo y parche adhesivo
WO2014057928A1 (ja)	2012-10-11	2014-04-17	久光製薬株式会社	貼付剤
US20160354322A1 (en)	2014-01-31	2016-12-08	Hisamitsu Pharmaceutical Co., Inc.	Emedastine-Containing Tape Preparation
JP6488021B2 (ja) *	2015-10-06	2019-03-20	久光製薬株式会社	アクリル系粘着剤の流動化抑制方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4299826A (en) *	1979-10-12	1981-11-10	The Procter & Gamble Company	Anti-acne composition
JPS5879983A (ja) *	1981-11-06	1983-05-13	Kanebo Ltd	新規なベンズイミダゾ−ル誘導体、その製造法およびその医薬組成物
JPH0764754B2 (ja) *	1984-10-02	1995-07-12	花王株式会社	経皮吸収促進剤及びこれを含有する皮膚外用剤
JPH01207246A (ja) *	1988-02-12	1989-08-21	Nissan Chem Ind Ltd	外用製剤用基剤組成物及び外用医薬組成物

1989
- 1989-08-28 JP JP1220788A patent/JPH0383924A/ja active Pending
1990
- 1990-08-23 DE DE90912459T patent/DE69004561T2/de not_active Expired - Fee Related
- 1990-08-23 ES ES90912459T patent/ES2062545T3/es not_active Expired - Lifetime
- 1990-08-23 AT AT90912459T patent/ATE97000T1/de not_active IP Right Cessation
- 1990-08-23 US US08/022,382 patent/US5321022A/en not_active Expired - Fee Related
- 1990-08-23 DK DK90912459.6T patent/DK0440811T3/da active
- 1990-08-23 KR KR1019910700424A patent/KR920700647A/ko not_active Ceased
- 1990-08-23 WO PCT/JP1990/001073 patent/WO1991003244A1/ja not_active Ceased
- 1990-08-23 EP EP90912459A patent/EP0440811B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0440811A4 (en)	1992-01-02
KR920700647A (ko)	1992-08-10
DK0440811T3 (da)	1993-12-27
DE69004561D1 (de)	1993-12-16
EP0440811A1 (de)	1991-08-14
US5321022A (en)	1994-06-14
EP0440811B1 (de)	1993-11-10
WO1991003244A1 (fr)	1991-03-21
JPH0383924A (ja)	1991-04-09
DE69004561T2 (de)	1994-04-28
ES2062545T3 (es)	1994-12-16

Legal Events

Date	Code	Title	Description
1994-09-15	UEP	Publication of translation of european patent specification
1998-05-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE97000T1 (de)	1993-11-15	Zubereitung zur perkutanen anwendung.
MY110765A (en)	1999-03-31	Compositions containing cholesteryl esters of unsaturated fatty acids
SE8405929D0 (sv)	1984-11-23	Farmaceutisk komposition
DE3772899D1 (de)	1991-10-17	Reinigungsmittel.
AU543727B2 (en)	1985-05-02	Injectable composition of rapamycin
JPS6485660A (en)	1989-03-30	Suture coated with sugar fatty acid ester
IL77751A (en)	1989-10-31	Preparation of optically active esters of(ar)aliphatic acids by candida cylindracea lipase resolution
AU5829186A (en)	1986-12-11	2-thio or oxo-4-aryl or heterocyclo-1,5 (2h)- pyrimidinedi-carboxylic acid diesters and 3-acyl-5- pyrimidinecarboxylic acids and esters
NO176082C (no)	1995-02-01	Fremgangsmåte for fremstilling av et farmasöytisk preparat inneholdende bunazosin, for perkutan tilförsel
HU896123D0 (en)	1990-02-28	Pharmaceutical compositions
ES2087471T3 (es)	1996-07-16	Esteres gelan.
GB1365398A (en)	1974-09-04	Stick for the application of adhesive to substrates
IT8748221A0 (it)	1987-07-24	Procedimento di preparazione di esteri di acidi carbossilici insaturi
AU3674589A (en)	1990-01-04	Skin- or hair-care compositions containing silica and carboxylic acid esters
HUT51105A (en)	1990-04-28	Pesticide comprising substituted acrylic acid ester derivatives as active ingredient and process for producing the active ingredients
WO1992017064A3 (en)	1992-12-10	Inhibitors of protein kinase C function
PH21875A (en)	1988-03-25	Novel carboxylic acid esters,their method of use and insecticides containing them as the active ingredient
DE3666807D1 (en)	1989-12-14	Process for the preparation of esters of alpha-ethylenically unsaturated alcohols and alpha-ethylenically unsaturated carboxylic acids
HUT44005A (en)	1988-01-28	Insecticide and acaricide compositions containing esters of carbamic acids as active components and process for producing the active components
AU645595B2 (en)	1994-01-20	Method for racemization of non-racemic 3-oxocyclopentane or 3-oxocyclohexane carboxylic acids and their esters with C1-C6 alcohols
KR930001889A (ko)	1993-02-22	갈랑긴의 안정화 방법
IT8268081A0 (it)	1982-09-10	Procedimento per la preparazionedi esteri di acidi carbossilici con alcooli contenenti gruppi epossidici
PL292804A1 (en)	1993-06-28	Method of obtaining esters of active carboxylic acids in particular n-hydroxysuccinoimidic or n-hydroxybenzotriazolic ones
AU2300588A (en)	1989-03-01	Caffeic acid esters and method of preparing and using same
IT8423885A1 (it)	1986-06-05	Procedimento per la preparazione di esteri e/o sali di acidi alfa-beta insaturi