DK0440811T3 - Præparater til perkutan administration - Google Patents

Præparater til perkutan administration

Info

Publication number: DK0440811T3
Authority: DK; Denmark
Prior art keywords: ethyl; ester; pref; emedastine; esters
Prior art date: 1989-08-28

Application number

DK90912459.6T

Other languages

English (en)

Inventor

Hiroshi Nakagawa

Shoichi Harada

Original Assignee

Kanebo Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-28

Filing date

1990-08-23

Publication date

1993-12-27

1990-08-23 Application filed by Kanebo Ltd filed Critical Kanebo Ltd

1993-12-27 Application granted granted Critical

1993-12-27 Publication of DK0440811T3 publication Critical patent/DK0440811T3/da

Links

238000002360 preparation method Methods 0.000 title 1
KBUZBQVCBVDWKX-UHFFFAOYSA-N emedastine Chemical compound N=1C2=CC=CC=C2N(CCOCC)C=1N1CCCN(C)CC1 KBUZBQVCBVDWKX-UHFFFAOYSA-N 0.000 abstract 4
150000002148 esters Chemical class 0.000 abstract 4
229960000325 emedastine Drugs 0.000 abstract 3
125000001931 aliphatic group Chemical group 0.000 abstract 2
-1 aliphatic monocarboxylic acids Chemical class 0.000 abstract 2
125000005907 alkyl ester group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
RGXWDWUGBIJHDO-UHFFFAOYSA-N ethyl decanoate Chemical compound CCCCCCCCCC(=O)OCC RGXWDWUGBIJHDO-UHFFFAOYSA-N 0.000 abstract 2
SHZIWNPUGXLXDT-UHFFFAOYSA-N ethyl hexanoate Chemical compound CCCCCC(=O)OCC SHZIWNPUGXLXDT-UHFFFAOYSA-N 0.000 abstract 2
MMXKVMNBHPAILY-UHFFFAOYSA-N ethyl laurate Chemical compound CCCCCCCCCCCC(=O)OCC MMXKVMNBHPAILY-UHFFFAOYSA-N 0.000 abstract 2
MMKRHZKQPFCLLS-UHFFFAOYSA-N ethyl myristate Chemical compound CCCCCCCCCCCCCC(=O)OCC MMKRHZKQPFCLLS-UHFFFAOYSA-N 0.000 abstract 2
YYZUSRORWSJGET-UHFFFAOYSA-N ethyl octanoate Chemical group CCCCCCCC(=O)OCC YYZUSRORWSJGET-UHFFFAOYSA-N 0.000 abstract 2
WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 abstract 1
QMMJWQMCMRUYTG-UHFFFAOYSA-N 1,2,4,5-tetrachloro-3-(trifluoromethyl)benzene Chemical compound FC(F)(F)C1=C(Cl)C(Cl)=CC(Cl)=C1Cl QMMJWQMCMRUYTG-UHFFFAOYSA-N 0.000 abstract 1
LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 abstract 1
HBTAOSGHCXUEKI-UHFFFAOYSA-N 4-chloro-n,n-dimethyl-3-nitrobenzenesulfonamide Chemical compound CN(C)S(=O)(=O)C1=CC=C(Cl)C([N+]([O-])=O)=C1 HBTAOSGHCXUEKI-UHFFFAOYSA-N 0.000 abstract 1
HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 abstract 1
QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 abstract 1
VIZORQUEIQEFRT-UHFFFAOYSA-N Diethyl adipate Chemical compound CCOC(=O)CCCCC(=O)OCC VIZORQUEIQEFRT-UHFFFAOYSA-N 0.000 abstract 1
LVGKNOAMLMIIKO-UHFFFAOYSA-N Elaidinsaeure-aethylester Natural products CCCCCCCCC=CCCCCCCCC(=O)OCC LVGKNOAMLMIIKO-UHFFFAOYSA-N 0.000 abstract 1
OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 abstract 1
239000005642 Oleic acid Substances 0.000 abstract 1
DHAZIUXMHRHVMP-UHFFFAOYSA-N butyl tetradecanoate Chemical compound CCCCCCCCCCCCCC(=O)OCCCC DHAZIUXMHRHVMP-UHFFFAOYSA-N 0.000 abstract 1
239000006071 cream Substances 0.000 abstract 1
PEUGOJXLBSIJQS-UHFFFAOYSA-N diethyl octanedioate Chemical compound CCOC(=O)CCCCCCC(=O)OCC PEUGOJXLBSIJQS-UHFFFAOYSA-N 0.000 abstract 1
229940031578 diisopropyl adipate Drugs 0.000 abstract 1
QYDYPVFESGNLHU-UHFFFAOYSA-N elaidic acid methyl ester Natural products CCCCCCCCC=CCCCCCCCC(=O)OC QYDYPVFESGNLHU-UHFFFAOYSA-N 0.000 abstract 1
239000000839 emulsion Substances 0.000 abstract 1
LVGKNOAMLMIIKO-QXMHVHEDSA-N ethyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC LVGKNOAMLMIIKO-QXMHVHEDSA-N 0.000 abstract 1
229940093471 ethyl oleate Drugs 0.000 abstract 1
239000000499 gel Substances 0.000 abstract 1
QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 abstract 1
XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 abstract 1
239000006210 lotion Substances 0.000 abstract 1
QYDYPVFESGNLHU-KHPPLWFESA-N methyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC QYDYPVFESGNLHU-KHPPLWFESA-N 0.000 abstract 1
229940073769 methyl oleate Drugs 0.000 abstract 1
150000002762 monocarboxylic acid derivatives Chemical class 0.000 abstract 1
WIBFFTLQMKKBLZ-SEYXRHQNSA-N n-butyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCCCC WIBFFTLQMKKBLZ-SEYXRHQNSA-N 0.000 abstract 1
KSCKTBJJRVPGKM-UHFFFAOYSA-N octan-1-olate;titanium(4+) Chemical compound [Ti+4].CCCCCCCC[O-].CCCCCCCC[O-].CCCCCCCC[O-].CCCCCCCC[O-] KSCKTBJJRVPGKM-UHFFFAOYSA-N 0.000 abstract 1
ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 abstract 1
239000007921 spray Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oil, Petroleum & Natural Gas (AREA)
Dermatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Immunology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK90912459.6T 1989-08-28 1990-08-23 Præparater til perkutan administration DK0440811T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP1220788A JPH0383924A (ja)	1989-08-28	1989-08-28	経皮投与用組成物

Publications (1)

Publication Number	Publication Date
DK0440811T3 true DK0440811T3 (da)	1993-12-27

Family

ID=16756579

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90912459.6T DK0440811T3 (da)	1989-08-28	1990-08-23	Præparater til perkutan administration

Country Status (9)

Country	Link
US (1)	US5321022A (da)
EP (1)	EP0440811B1 (da)
JP (1)	JPH0383924A (da)
KR (1)	KR920700647A (da)
AT (1)	ATE97000T1 (da)
DE (1)	DE69004561T2 (da)
DK (1)	DK0440811T3 (da)
ES (1)	ES2062545T3 (da)
WO (1)	WO1991003244A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3527256B2 (ja) *	1992-12-09	2004-05-17	ロート製薬株式会社	抗アレルギー点眼剤
FR2727865B1 (fr) *	1994-12-08	1997-07-18	Esteve Labor Dr	Utilisation des derives de 2-(4-(azolybutyl)-piperazinyl- (methyl))-benzimidazole et analogues ainsi que de leurs sels, pour la preparation de medicaments destines au traitement ou a la prophylaxie de l'asthme
KR19990008108A (ko) *	1995-04-27	1999-01-25	이시하라소이치	에메다스틴을 함유하는 외용제
IT1318705B1 (it) *	2000-09-22	2003-08-27	Gianluigi Ciocca	Medicamento transdermico ad alta penetrazione.
JP5160018B2 (ja)	2002-06-25	2013-03-13	アクルックス・ディ・ディ・エス・プロプライエタリー・リミテッド	非晶質医薬組成物を用いる経皮送達速度調節
AUPS317302A0 (en) *	2002-06-25	2002-07-18	Drug Delivery Solutions Pty Ltd	Metastable pharmaceutical compositions
CN103501770B (zh)	2011-04-18	2015-04-29	久光制药株式会社	贴附剂的制造方法及贴附剂
EP2907515B1 (en)	2012-10-11	2019-01-02	Hisamitsu Pharmaceutical Co., Inc.	Skin patch
US20160354322A1 (en)	2014-01-31	2016-12-08	Hisamitsu Pharmaceutical Co., Inc.	Emedastine-Containing Tape Preparation
WO2017061393A1 (ja) *	2015-10-06	2017-04-13	久光製薬株式会社	貼付剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4299826A (en) *	1979-10-12	1981-11-10	The Procter & Gamble Company	Anti-acne composition
JPS5879983A (ja) *	1981-11-06	1983-05-13	Kanebo Ltd	新規なベンズイミダゾ−ル誘導体、その製造法およびその医薬組成物
JPH0764754B2 (ja) *	1984-10-02	1995-07-12	花王株式会社	経皮吸収促進剤及びこれを含有する皮膚外用剤
JPH01207246A (ja) *	1988-02-12	1989-08-21	Nissan Chem Ind Ltd	外用製剤用基剤組成物及び外用医薬組成物

1989
- 1989-08-28 JP JP1220788A patent/JPH0383924A/ja active Pending
1990
- 1990-08-23 DK DK90912459.6T patent/DK0440811T3/da active
- 1990-08-23 WO PCT/JP1990/001073 patent/WO1991003244A1/ja not_active Ceased
- 1990-08-23 ES ES90912459T patent/ES2062545T3/es not_active Expired - Lifetime
- 1990-08-23 KR KR1019910700424A patent/KR920700647A/ko not_active Ceased
- 1990-08-23 DE DE90912459T patent/DE69004561T2/de not_active Expired - Fee Related
- 1990-08-23 EP EP90912459A patent/EP0440811B1/en not_active Expired - Lifetime
- 1990-08-23 US US08/022,382 patent/US5321022A/en not_active Expired - Fee Related
- 1990-08-23 AT AT90912459T patent/ATE97000T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
ATE97000T1 (de)	1993-11-15
DE69004561D1 (de)	1993-12-16
EP0440811A1 (en)	1991-08-14
US5321022A (en)	1994-06-14
ES2062545T3 (es)	1994-12-16
EP0440811A4 (en)	1992-01-02
KR920700647A (ko)	1992-08-10
EP0440811B1 (en)	1993-11-10
DE69004561T2 (de)	1994-04-28
WO1991003244A1 (fr)	1991-03-21
JPH0383924A (ja)	1991-04-09

Publication	Publication Date	Title
SE8405929L (sv)	1985-08-02	Farmaceutisk komposition
FI935463A0 (fi)	1993-12-07	Klorfluorkolfria aerosolformulationer
DE3772899D1 (de)	1991-10-17	Reinigungsmittel.
ES2062545T3 (es)	1994-12-16	Composicion para la administracion percutanea.
MY110765A (en)	1999-03-31	Compositions containing cholesteryl esters of unsaturated fatty acids
ATE91894T1 (de)	1993-08-15	Arzneizubereitungen zur transdermalen verabreichung von wirkstoffen.
AU5829186A (en)	1986-12-11	2-thio or oxo-4-aryl or heterocyclo-1,5 (2h)- pyrimidinedi-carboxylic acid diesters and 3-acyl-5- pyrimidinecarboxylic acids and esters
ZA898331B (en)	1990-07-25	Pharmaceutical compositions
NZ306510A (en)	1999-05-28	Niacin derivatives which include a fatty acid or fatty acid alcohol residue and their use in medicaments and skin care compositions
ES2087471T3 (es)	1996-07-16	Esteres gelan.
AU3674589A (en)	1990-01-04	Skin- or hair-care compositions containing silica and carboxylic acid esters
HUT42691A (en)	1987-08-28	Process for preparing carboxylic acid ester derivatives and insecticidal preparations containing the same as active substance
DE3666807D1 (en)	1989-12-14	Process for the preparation of esters of alpha-ethylenically unsaturated alcohols and alpha-ethylenically unsaturated carboxylic acids
AU645595B2 (en)	1994-01-20	Method for racemization of non-racemic 3-oxocyclopentane or 3-oxocyclohexane carboxylic acids and their esters with C1-C6 alcohols
KR930001889A (ko)	1993-02-22	갈랑긴의 안정화 방법
FR2720229B1 (fr)	2001-08-31	Utilisation d'au moins un acide gras éventuellement associé à au moins un ester d'acide gras, contre la ponte des lepidoptères tortricides.
IT8423885A0 (it)	1984-12-05	Procedimento per la preparazione di esteri e/o sali di acidi alfa-beta insaturi.
GB9222655D0 (en)	1992-12-09	Method for the safe administration of fatty acids and theirlithium salts