BA98300A - Pirolidin derivati - Google Patents

Pirolidin derivati

Info

Publication number: BA98300A
Authority: BA; Bosnia and Herzegovina
Prior art keywords: chem; formula; pyrrolidine derivatives; pyrrolidine; ch2s
Prior art date: 1989-03-17

Application number

BA980300A

Other languages

Bosnian (bs)

English (en)

Inventor

Alexander Roderick Mackenzie

Peter Edward Cross

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-17

Filing date

1998-03-30

Publication date

2001-09-14

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10653525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BA98300(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-03-30 Application filed by Pfizer filed Critical Pfizer

2001-09-14 Publication of BA98300A publication Critical patent/BA98300A/bs

Links

150000003235 pyrrolidines Chemical class 0.000 title 1
RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 3
229940121948 Muscarinic receptor antagonist Drugs 0.000 abstract 1
208000002551 irritable bowel syndrome Diseases 0.000 abstract 1
125000003373 pyrazinyl group Chemical group 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pulmonology (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)
Saccharide Compounds (AREA)

BA980300A 1989-03-17 1998-03-30 Pirolidin derivati BA98300A (bs)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB898906166A GB8906166D0 (en)	1989-03-17	1989-03-17	Therapeutic agents
YU52790A YU47587B (sh)	1989-03-17	1990-03-16	Pirolidin derivati

Publications (1)

Publication Number	Publication Date
BA98300A true BA98300A (bs)	2001-09-14

Family

ID=10653525

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BA980300A BA98300A (bs)	1989-03-17	1998-03-30	Pirolidin derivati

Country Status (37)

Country	Link
US (1)	US5096890B1 (fr)
EP (1)	EP0388054B1 (fr)
JP (2)	JPH0764809B2 (fr)
KR (2)	KR920008166B1 (fr)
CN (1)	CN1023007C (fr)
AT (1)	ATE96783T1 (fr)
AU (1)	AU614224B2 (fr)
BA (1)	BA98300A (fr)
CA (1)	CA2012295C (fr)
CL (1)	CL2003002756A1 (fr)
CY (2)	CY1812A (fr)
CZ (1)	CZ280053B6 (fr)
DD (1)	DD292911A5 (fr)
DE (2)	DE69004302T2 (fr)
DK (1)	DK0388054T3 (fr)
EG (1)	EG18951A (fr)
ES (1)	ES2060020T3 (fr)
FI (1)	FI95573C (fr)
GB (1)	GB8906166D0 (fr)
HK (1)	HK130294A (fr)
HU (2)	HU217433B (fr)
IE (1)	IE62515B1 (fr)
IL (1)	IL93694A (fr)
LU (1)	LU91161I2 (fr)
MX (1)	MX9319890A (fr)
MY (1)	MY105527A (fr)
NL (1)	NL300191I2 (fr)
NO (2)	NO176316C (fr)
NZ (1)	NZ232958A (fr)
PL (1)	PL164136B1 (fr)
PT (1)	PT93443B (fr)
RU (2)	RU1833374C (fr)
SG (1)	SG143394G (fr)
SK (1)	SK129590A3 (fr)
UA (1)	UA18263A (fr)
YU (1)	YU47587B (fr)
ZA (1)	ZA901982B (fr)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
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GB8825505D0 (en) *	1988-11-01	1988-12-07	Pfizer Ltd	Therapeutic agents
US5932594A (en) *	1988-11-01	1999-08-03	Pfizer, Inc.	Muscarinic receptor antagonists
GB8928042D0 (en) *	1989-12-12	1990-02-14	Pfizer Ltd	Muscarinic receptor antagonists
US5486527A (en) *	1990-01-06	1996-01-23	Pfizer Inc.	Anticholinergic agents
US5607950A (en) *	1990-01-06	1997-03-04	Pfizer Inc.	Muscarinic receptor antagonists
KR100259107B1 (ko) *	1992-04-23	2000-07-01	슈테펜 엘. 네스비트	세로토닌 5ht₂길항제로서의 4-이미도메틸-1-[2'-페닐-2'-옥소에틸]피페리딘, 이의 제조방법 및 이를 포함하는 약제학적 조성물
GB9400600D0 (en) *	1994-01-14	1994-03-09	Pfizer Ltd	Treatment of motion seckness
US5639763A (en) *	1994-03-01	1997-06-17	Fmc Corporation	Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
US6017931A (en) *	1994-03-01	2000-01-25	Fmc Corporation	Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
US5674891A (en) *	1994-07-27	1997-10-07	The Procter & Gamble Company	Dihydrobenzothiophene compounds useful as anti-inflammatory agents
CN1191243C (zh) *	1994-07-27	2005-03-02	范德比尔特大学	用作抗炎剂的二氢苯并呋喃和相关化合物
GB9518953D0 (en) *	1995-09-15	1995-11-15	Pfizer Ltd	Pharmaceutical formulations
US5672620A (en) *	1996-02-01	1997-09-30	The Procter & Gamble Company	Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5684031A (en) *	1996-02-01	1997-11-04	The Procter & Gamble Company	Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
JP4167302B2 (ja) *	1996-12-02	2008-10-15	杏林製薬株式会社	新規ｎ―置換ピロリジン誘導体及びその製造法
US6131129A (en) *	1997-07-30	2000-10-10	Sony Corporation Of Japan	Computer system within an AV/C based media changer subunit providing a standarized command set
US6693202B1 (en)	1999-02-16	2004-02-17	Theravance, Inc.	Muscarinic receptor antagonists
IL141235A (en) *	2000-02-09	2012-04-30	Novartis Int Pharm Ltd	Combined use of an alpha-adrenoceptor antagonist and a muscarinic antagonist in the preparation of a drug for the treatment of non-malignant prostatic hyperplasia
US6653339B2 (en)	2001-08-15	2003-11-25	Pfizer Inc.	Method of treating irritable bowel syndrome
EP1461306B1 (fr) *	2001-10-26	2008-12-24	Pharmacia & Upjohn Company LLC	Composes d'ammonium quaternaires et leur utilisation comme agents antimuscariniques
SE0103668D0 (sv) *	2001-11-02	2001-11-02	Astrazeneca Ab	Method for the treatment of overactive blader
JP2005511582A (ja) *	2001-11-05	2005-04-28	ファルマシアアンドアップジョンカンパニーリミティドライアビリティーカンパニー	抗ムスカリン・エアゾール
GB0129962D0 (en) *	2001-12-14	2002-02-06	Pfizer Ltd	Method of treatment
GB0207104D0 (en)	2002-03-26	2002-05-08	Pfizer Ltd	Stable hydrate of a muscarinic receptor antagonist
DE60230683D1 (de)	2002-07-08	2009-02-12	Ranbaxy Lab Ltd	3,6-disubstituierte azabicyclo-3.1.0 hexan-derivat
DE60226906D1 (de)	2002-07-31	2008-07-10	Ranbaxy Lab Ltd	3,6-disubstituierte azabicyclo ä3.1.0ühexanderivate, die sich als muscarinrezeptorantagonisten eignen
AU2002321711A1 (en)	2002-08-09	2004-02-25	Ranbaxy Laboratories Limited	3,6-disubstituted azabicyclo (3.1.0) hexane derivatives useful as muscarinic receptor antagonist
WO2004018422A1 (fr)	2002-08-23	2004-03-04	Ranbaxy Laboratories Limited	Derives d'azabicyclo(3.1.0)hexanes 3,6-disubstitues contenant fluoro et sulfonylamino, utilises comme antagonistes des recepteurs de muscarine
TW200412945A (en) *	2002-10-25	2004-08-01	Upjohn Co	Quaternary ammonium compounds
TW200800953A (en)	2002-10-30	2008-01-01	Theravance Inc	Intermediates for preparing substituted 4-amino-1-(pyridylmethyl) piperidine
DE60227576D1 (de)	2002-12-10	2008-08-21	Ranbaxy Lab Ltd	3,6-DISUBSTITUIERTE AZABICYCLO i3.1.0 -HEXANDERIVATIVE ALS ANTAGONISTEN DES MUSCARINREZEPTORS
AU2002347553A1 (en)	2002-12-23	2004-07-14	Ranbaxy Laboratories Limited	Flavaxate derivatives as muscarinic receptor antagonists
EP1583741A1 (fr)	2002-12-23	2005-10-12	Ranbaxy Laboratories, Limited	Derives de 1-substitues-3-pyrrolidines comme antagonistes de recepteurs muscariniques
US7488748B2 (en)	2003-01-28	2009-02-10	Ranbaxy Laboratories Limited	3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists
JP4767842B2 (ja)	2003-04-01	2011-09-07	セラヴァンス，インコーポレーテッド	β２アドレナリン作用性レセプターアゴニスト活性およびムスカリン性レセプターアンタゴニスト活性を有するジアリールメチル化合物および関連化合物
US7517905B2 (en)	2003-04-09	2009-04-14	Ranbaxy Laboratories Limited	Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists
US7560479B2 (en)	2003-04-10	2009-07-14	Ranbaxy Laboratories Limited	3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists
JP2006514978A (ja)	2003-04-10	2006-05-18	ランバクシーラボラトリーズリミテッド	ムスカリン受容体アンタゴニストである置換アザビシクロヘキサン誘導体
CA2522071A1 (fr)	2003-04-11	2004-10-21	Ranbaxy Laboratories Limited	Derives azabicyclo utiles comme antagonistes du recepteur muscarinique
US20040242569A1 (en) *	2003-04-15	2004-12-02	Pfizer Inc.	Quatemary ammonium compounds
WO2004091597A2 (fr) *	2003-04-15	2004-10-28	Pharmacia & Upjohn Company Llc	Procede pour traiter le syndrome du colon irritable
MXPA05011225A (es) *	2003-04-18	2005-12-14	Pharmacia & Upjohn Co Llc	Politerapias.
TW200510298A (en) *	2003-06-13	2005-03-16	Theravance Inc	Substituted pyrrolidine and related compounds
EP1644356A1 (fr)	2003-07-11	2006-04-12	Theravance, Inc.	Composes de 4-amino-1-benzylpiperidine substitues
JP2007528418A (ja) *	2004-03-11	2007-10-11	セラヴァンス，インコーポレーテッド	ムスカリンレセプターアンタゴニストとしての有用なジフェニルメチル化合物
US7071224B2 (en) *	2004-03-11	2006-07-04	Theravance, Inc.	Diphenylmethyl compounds useful as muscarinic receptor antagonists
WO2005092341A1 (fr) *	2004-03-22	2005-10-06	Ranbaxy Laboratories Limited	Therapie combinee destinee a reduire les symptomes des voies urinaires
RU2008119323A (ru)	2005-10-19	2009-11-27	Рэнбакси Лабораториз Лимитед (In)	Фармацевтические композиции мускаринового рецептора
EP1891034A2 (fr) *	2005-12-27	2008-02-27	Teva Pharmaceutical Fine Chemicals S.R.L.	Procedes de preparation de bromhydrate de darifenacine
AR062676A1 (es) *	2006-09-07	2008-11-26	Medichem Sa	Procedimiento mejorado para preparar compuestos de pirrolidina 1,3-disustituidas
EP2114972A2 (fr) *	2006-12-13	2009-11-11	Gilead Sciences, Inc.	Monophosphates utilisés comme promédicaments mutuels d'antagonistes des récepteurs muscariniques et de beta-agonistes dans le traitement de la b.p.c.o. et de la bronchite chronique
WO2008100651A2 (fr) *	2007-01-05	2008-08-21	Dr. Reddy's Laboratories Ltd.	Préparation de darifénacine et ses sels
WO2008103426A1 (fr) *	2007-02-23	2008-08-28	Theravance, Inc.	Composés de diphénylméthyle d'ammonium quartenaire utilisés comme antagonistes de récepteur muscarinique
WO2008126106A2 (fr) *	2007-04-16	2008-10-23	Manne Satyanarayana Reddy	Procédés nouveaux et perfectionnés pour la préparation d'intermédiaires de darifénacine, de la darifénacine et de ses sels pharmaceutiquement acceptables
WO2009007853A2 (fr) *	2007-06-08	2009-01-15	Actavis Group Ptc Ehf	Nouveaux polymorphes de la base libre de darifénacine et son sel d'hydrobromure
WO2008152497A1 (fr) *	2007-06-15	2008-12-18	Medichem, S.A.	Procédé de détermination de la pureté énantiomérique de la darifénacine et de ses intermédiaires
US20090005431A1 (en) *	2007-06-30	2009-01-01	Auspex Pharmaceuticals, Inc.	Substituted pyrrolidines
US20090018346A1 (en) *	2007-07-13	2009-01-15	Medichem, S.A.	Amorphous Form Of Darifenacin Hydrobromide And Processes For The Preparation Thereof
CZ200845A3 (cs) *	2008-01-28	2009-09-02	Zentiva, A. S.	Zpusob prípravy Darifenacinu
WO2009125430A2 (fr) *	2008-03-17	2009-10-15	Matrix Laboratoires Limited	Procédé perfectionné pour la fabrication de darifénacine
CN101983187A (zh) *	2008-04-02	2011-03-02	株式会社钟化	(s)-3-(1-氰基-1，1-二苯基甲基)吡咯烷的制备方法
US20110144354A1 (en) *	2008-09-22	2011-06-16	Watson Pharma Private Limited	Process for Preparation of Darifenacin and Intermediates Used in the Process
EP2236509A1 (fr)	2009-04-01	2010-10-06	Ragactives, S.L.	Méthode de préparation de dérivés de la pyrrolidine 1,3 substituée
NZ610978A (en)	2009-05-15	2014-11-28	Redx Pharma Ltd	Redox drug derivatives
WO2011070419A1 (fr)	2009-12-10	2011-06-16	Aurobindo Pharma Limited	Procédé perfectionné pour la préparation de bromhydrate de darifénacine
JP5812500B2 (ja)	2010-04-30	2015-11-17	メルク・シャープ・エンド・ドーム・コーポレイション	新規なβ３アドレナリン作動性受容体アゴニスト
CN101857581A (zh) *	2010-06-22	2010-10-13	浙江美诺华药物化学有限公司	一种制备达非那新中间体5-(2-溴乙基)-2,3-二氢-1-苯并呋喃的方法
WO2011161504A1 (fr)	2010-06-23	2011-12-29	Micro Labs Limited	Formulations à libération prolongée contenant de la darifénacine ou des sels pharmaceutiquement acceptables de celle-ci

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US4002766A (en) *	1974-12-26	1977-01-11	A. H. Robins Company, Incorporated	Antiarrhythmia methods
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US4594343A (en) *	1984-10-19	1986-06-10	Shanklin Jr James R	1-[(aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl]-α,α-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles
IL76583A (en) *	1984-10-19	1988-08-31	Robins Co Inc A H	1-(aminoalkyl)-alpha'alpha-diaryl pyrrolidinyl,piperidino and homopiperidino acetamides and acetonitriles and pharmaceutical compositions containing them
EP0228893A3 (fr) *	1985-12-20	1990-01-03	A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation)	Amines arylalkyl-hétérocycliques N-substitués par un groupe aryloxyalkyl dans le traitement des allergies
IL78939A (en) *	1986-01-17	1990-04-29	Robins Co Inc A H	Pharmaceutical compositions containing n-substituted arylalkyl-and arylalkylene-piperidines and tetrahydropyridines and certain such novel compounds

1989
- 1989-03-17 GB GB898906166A patent/GB8906166D0/en active Pending
1990
- 1990-03-02 ES ES90302269T patent/ES2060020T3/es not_active Expired - Lifetime
- 1990-03-02 EP EP90302269A patent/EP0388054B1/fr not_active Expired - Lifetime
- 1990-03-02 DE DE90302269T patent/DE69004302T2/de not_active Expired - Lifetime
- 1990-03-02 DE DE200512000022 patent/DE122005000022I2/de active Active
- 1990-03-02 DK DK90302269.7T patent/DK0388054T3/da active
- 1990-03-02 AT AT90302269T patent/ATE96783T1/de active
- 1990-03-09 IL IL9369490A patent/IL93694A/en not_active IP Right Cessation
- 1990-03-13 US US07493068 patent/US5096890B1/en not_active Expired - Lifetime
- 1990-03-14 MX MX1989090A patent/MX9319890A/es unknown
- 1990-03-14 HU HU580/90A patent/HU217433B/hu unknown
- 1990-03-15 CA CA002012295A patent/CA2012295C/fr not_active Expired - Lifetime
- 1990-03-15 ZA ZA901982A patent/ZA901982B/xx unknown
- 1990-03-15 KR KR1019900003453A patent/KR920008166B1/ko not_active Expired
- 1990-03-15 JP JP2065521A patent/JPH0764809B2/ja not_active Expired - Lifetime
- 1990-03-15 EG EG17090A patent/EG18951A/xx active
- 1990-03-15 PT PT93443A patent/PT93443B/pt not_active IP Right Cessation
- 1990-03-16 AU AU51402/90A patent/AU614224B2/en not_active Expired
- 1990-03-16 RU SU904743599A patent/RU1833374C/ru active
- 1990-03-16 SK SK1295-90A patent/SK129590A3/sk not_active IP Right Cessation
- 1990-03-16 FI FI901333A patent/FI95573C/fi active Protection Beyond IP Right Term
- 1990-03-16 DD DD90338829A patent/DD292911A5/de not_active IP Right Cessation
- 1990-03-16 MY MYPI90000416A patent/MY105527A/en unknown
- 1990-03-16 NO NO901241A patent/NO176316C/no not_active IP Right Cessation
- 1990-03-16 NZ NZ232958A patent/NZ232958A/en unknown
- 1990-03-16 IE IE95590A patent/IE62515B1/en not_active IP Right Cessation
- 1990-03-16 CZ CS901295A patent/CZ280053B6/cs not_active IP Right Cessation
- 1990-03-16 YU YU52790A patent/YU47587B/sh unknown
- 1990-03-16 PL PL90284342A patent/PL164136B1/pl unknown
- 1990-03-16 UA UA4743599A patent/UA18263A/uk unknown
- 1990-03-17 CN CN90101543A patent/CN1023007C/zh not_active Expired - Lifetime
1991
- 1991-03-13 RU SU914894696A patent/RU2015965C1/ru active
1992
- 1992-08-12 KR KR1019920014485A patent/KR960015142B1/ko not_active Expired - Lifetime
1994
- 1994-09-26 JP JP6229807A patent/JPH07149640A/ja active Pending
- 1994-10-03 SG SG143394A patent/SG143394G/en unknown
- 1994-11-24 HK HK130294A patent/HK130294A/en not_active IP Right Cessation
1995
- 1995-06-28 HU HU95P/P00505P patent/HU211640A9/hu active Protection Beyond IP Right Term
- 1995-10-20 CY CY181295A patent/CY1812A/xx unknown
1998
- 1998-03-30 BA BA980300A patent/BA98300A/bs unknown
2003
- 2003-12-26 CL CL200302756A patent/CL2003002756A1/es unknown
2005
- 2005-04-01 NO NO2005008C patent/NO2005008I2/no unknown
- 2005-04-04 CY CY2005005C patent/CY2005005I2/el unknown
- 2005-04-08 NL NL300191C patent/NL300191I2/nl unknown
- 2005-04-11 LU LU91161C patent/LU91161I2/fr unknown

Also Published As

Publication number	Publication date
NL300191I1 (nl)	2005-07-01
NO2005008I1 (en)	2005-04-11
DE122005000022I2 (de)	2006-02-02
UA18263A (uk)	1997-12-25
CN1045580A (zh)	1990-09-26
KR900014367A (ko)	1990-10-23
HU901580D0 (en)	1990-06-28
EG18951A (en)	1994-03-30
GB8906166D0 (en)	1989-05-04
AU5140290A (en)	1990-09-20
ATE96783T1 (de)	1993-11-15
ZA901982B (en)	1991-10-30
CN1023007C (zh)	1993-12-08
MY105527A (en)	1994-10-31
US5096890A (en)	1992-03-17
NO176316B (no)	1994-12-05
NO901241L (no)	1990-09-18
CZ280053B6 (cs)	1995-10-18
NO2005008I2 (no)	2006-11-27
EP0388054A1 (fr)	1990-09-19
CY2005005I1 (el)	2010-07-28
ES2060020T3 (es)	1994-11-16
JPH07149640A (ja)	1995-06-13
RU2015965C1 (ru)	1994-07-15
NO901241D0 (no)	1990-03-16
US5096890B1 (en)	1995-03-28
CA2012295C (fr)	1996-11-12
CA2012295A1 (fr)	1990-09-17
IL93694A0 (en)	1990-12-23
NL300191I2 (nl)	2005-08-01
PT93443A (pt)	1990-11-07
AU614224B2 (en)	1991-08-22
SK278434B6 (en)	1997-05-07
JPH02282360A (ja)	1990-11-19
CY1812A (en)	1995-10-20
JPH0764809B2 (ja)	1995-07-12
EP0388054B1 (fr)	1993-11-03
IE900955L (en)	1990-09-17
PT93443B (pt)	1996-02-29
MX9319890A (es)	1993-08-01
PL164136B1 (pl)	1994-06-30
IE62515B1 (en)	1995-02-08
DE122005000022I1 (de)	2005-08-04
CL2003002756A1 (es)	2005-02-11
CY2005005I2 (el)	2010-07-28
FI901333A0 (fi)	1990-03-16
RU1833374C (ru)	1993-08-07
SG143394G (en)	1995-01-13
KR960015142B1 (ko)	1996-11-01
HUT58313A (en)	1992-02-28
YU47587B (sh)	1995-10-24
HK130294A (en)	1994-12-02
HU217433B (hu)	2000-01-28
FI95573C (fi)	1996-02-26
DE69004302D1 (de)	1993-12-09
DE69004302T2 (de)	1994-02-24
NO176316C (no)	1995-03-15
IL93694A (en)	1994-08-26
DD292911A5 (de)	1991-08-14
YU52790A (sh)	1992-07-20
HU211640A9 (en)	1995-12-28
SK129590A3 (en)	1997-05-07
NZ232958A (en)	1992-05-26
DK0388054T3 (da)	1993-12-06
CZ129590A3 (en)	1995-05-17
FI95573B (fi)	1995-11-15
KR920008166B1 (ko)	1992-09-24
LU91161I2 (fr)	2005-06-13

Publication	Publication Date	Title
US5096890B1 (en)	1995-03-28	Pyrrolidine derivatives
NO932607D0 (no)	1993-07-19	Piperidinderivater og anvendelse av disse
DE69007126D1 (de)	1994-04-07	Muscarin-rezeptor-antagonisten.
FI922835A0 (fi)	1992-06-17	Menetelmä terapeuttisesti aktiivisten piperidiinijohdannaisten valmistamiseksi
DE69006745D1 (de)	1994-03-24	Muscarin-rezeptor-antagonisten.