BE901737A - Composition pharmaceutique pour le traitement de l'ischemie myocardique aigue. - Google Patents

Composition pharmaceutique pour le traitement de l'ischemie myocardique aigue.

Info

Publication number
BE901737A
BE901737A BE0/214518A BE214518A BE901737A BE 901737 A BE901737 A BE 901737A BE 0/214518 A BE0/214518 A BE 0/214518A BE 214518 A BE214518 A BE 214518A BE 901737 A BE901737 A BE 901737A
Authority
BE
Belgium
Prior art keywords
treatment
pharmaceutical composition
myocardial ischemia
acute myocardial
polydeoxyribonucleotoide
Prior art date
Application number
BE0/214518A
Other languages
English (en)
Inventor
G Prino
M Mantovani
R Niada
Original Assignee
Crinos Industria Farmaco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crinos Industria Farmaco filed Critical Crinos Industria Farmaco
Publication of BE901737A publication Critical patent/BE901737A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)

Abstract

Compositions pour le traitement des états aigus d'ischémie et d'infarctus du myocarde comprenant comme ingrédient actif du défibrotide, un polydésoxyribonucléotoide obtenu par extraction à partir d'organes d'animaux, en combinaisonavec des véhicules et excipients usuels.
BE0/214518A 1984-02-16 1985-02-14 Composition pharmaceutique pour le traitement de l'ischemie myocardique aigue. BE901737A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8419645A IT1206341B (it) 1984-02-16 1984-02-16 Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio.

Publications (1)

Publication Number Publication Date
BE901737A true BE901737A (fr) 1985-05-29

Family

ID=11160049

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/214518A BE901737A (fr) 1984-02-16 1985-02-14 Composition pharmaceutique pour le traitement de l'ischemie myocardique aigue.

Country Status (9)

Country Link
US (1) US4693995A (fr)
EP (1) EP0152148B1 (fr)
JP (1) JPH0649651B2 (fr)
AT (1) ATE76296T1 (fr)
AU (1) AU585495B2 (fr)
BE (1) BE901737A (fr)
CH (1) CH662509A5 (fr)
DE (1) DE3505359C2 (fr)
IT (1) IT1206341B (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1170214B (it) * 1983-09-12 1987-06-03 Crinos Industria Farmaco Composizione farmaceutica per la cura delle arteriopatie periferiche
IT1190313B (it) * 1986-04-17 1988-02-16 Crinos Industria Farmaco Procedimento per l'ottenimento di polidesossiribonucleotidi chimicamente definiti e riproducibili e prodotto farmacologicamente attivo risultante
AU618723B2 (en) * 1986-10-06 1992-01-09 University Of Virginia Alumni Patents Foundation, The Use of an adenosine, hypoxanthine and ribose-containing solution for improved protection of the heart during surgery
IT1223322B (it) * 1987-10-23 1990-09-19 Crinos Industria Farmaco Metodo per prevenire la formazione di coaguli sanguigni nel circuito extracorporeo di apparecchi di dialisi a composizione utile per esso
IT1231509B (it) * 1989-09-07 1991-12-07 Crinos Industria Farmaco Composizione farmceutica ad uso topico per la terapia della fragilita' capillare.
US6699985B2 (en) * 1991-08-21 2004-03-02 Arsinur Burcoglu Method of treating HIV infection and related secondary infections thereof
US5977083A (en) * 1991-08-21 1999-11-02 Burcoglu; Arsinur Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states
US5624912A (en) * 1991-08-21 1997-04-29 Burcoglu; Arsinur Method of treating HIV infection and related secondary infections with defibrotide
IT1252174B (it) * 1991-12-09 1995-06-05 Crinos Industria Farmaco Oligodesossimibonucleotidi ad attivita' antiischemica e procedimenti per il loro ottenimento
AU692433B2 (en) * 1993-01-13 1998-06-11 Arsinur Burcoglu Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states
TW280772B (fr) * 1993-08-25 1996-07-11 Otsuka Pharma Factory Inc
US5852000A (en) * 1993-08-25 1998-12-22 Otsuka Pharmaceutical Factory, Inc. Cardiac rehabilitation agent
AU754242B2 (en) * 1997-04-28 2002-11-07 Arsinur Burcoglu Method of treating HIV infection and related secondary infections thereof
US7252818B2 (en) * 1998-07-24 2007-08-07 Cardiovascular Biotherapeutics, Inc. Method of producing biologically active human acidic fibroblast growth factor and its use in promoting angiogenesis
EP1147777A1 (fr) 2000-04-18 2001-10-24 Crinos Industria Farmacobiologica S.p.A. Combinaison de Defibrotide et de G-CSF et son utilisation pour activer les cellules progénitrices haematopoiétiques
EP1325962A1 (fr) * 2001-12-17 2003-07-09 Gentium S.p.A. Procédé pour la détermination de l'activité biologique de la defibrotide
EP1495702A1 (fr) 2003-07-10 2005-01-12 Nestec S.A. Dispositif pour l'extraction d'une capsule
ITMI20031714A1 (it) * 2003-09-05 2005-03-06 Gentium Spa Formazioni ad azione antitumorale.
KR20070121001A (ko) * 2005-03-03 2007-12-26 젠티엄 에스피에이 신혈관 형성-의존성 종양 치료용 약학적 제제
EP1872787A1 (fr) * 2006-06-27 2008-01-02 Gentium S.p.A. Utilisation de defibrotide pour l'inhibition de l'heparanase
EP1982722A1 (fr) * 2007-04-16 2008-10-22 Gentium S.p.A. Utilisation de oligotide pour le traitement de maladies rénales
EP2103689A1 (fr) * 2008-03-19 2009-09-23 Gentium S.p.A. Oligonucléotides phosphodiesters synthétiques et leurs utilisations thérapeutiques
IT1406068B1 (it) 2010-07-22 2014-02-06 Medestea Int Spa Polidesossiribonucleotidi (pdrn) per l'impiego nel trattamento di condizioni di acidosi e composizioni a base di polidesossiribonucleotidi per il suddetto impiego
DE102010039631A1 (de) 2010-08-22 2012-02-23 Ulrich Schubert Pharmazeutische Zusammensetzungen mit immunmodulatorischen Eigenschaften
DK2637672T3 (en) 2010-11-12 2018-10-22 Gentium S R L DEFIBROTID FOR USE IN PROPHYLAXY AND / OR TREATMENT OF GRAPHIC VERSUS HOST DISEASE (GVHD)
KR102038357B1 (ko) 2012-06-22 2019-10-31 젠티엄 에스알엘 디파이브로타이드의 생물학적 활성 측정을 위한 유우글로불린에 기초한 방법
EP3026122A1 (fr) 2014-11-27 2016-06-01 Gentium S.p.A. Procédé à base cellulaire pour déterminer la puissance de défibrotide
CN111132663A (zh) 2017-08-03 2020-05-08 爵士制药爱尔兰有限公司 包含高浓度核酸的制剂
AU2019252790A1 (en) 2018-04-12 2020-10-15 Jazz Pharmaceuticals, Inc. Defibrotide for the prevention and treatment of cytokine release syndrome and neurotoxicity associated with immunodepletion
US20220023533A1 (en) 2018-12-07 2022-01-27 Jazz Phrmaceticals Ireland Limited Subcutaneous delivery of high concentration formulations
WO2021174039A1 (fr) 2020-02-28 2021-09-02 Jazz Pharmaceuticals Ireland Limited Administration de formulations de faible viscosité
EP4135717A1 (fr) 2020-04-17 2023-02-22 Jazz Pharmaceuticals Ireland Limited Traitement de défibrotide pour la prévention d'un rejet et d'une lésion d'organe
TW202308659A (zh) 2021-05-06 2023-03-01 愛爾蘭商爵士製藥愛爾蘭有限責任公司 用於急性呼吸窘迫症候群之治療及預防的去纖維蛋白多核苷酸

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1043823B (it) * 1970-11-03 1980-02-29 Prephar Procedimento per l estrazione di acidi nucleici da organi animali
US3899481A (en) * 1970-11-03 1975-08-12 Crinos Industria Farmaco Process for the controlled partial degradation of deoxyribonucleic acid extracted from animal organs
DE2154279A1 (de) * 1970-11-03 1972-05-25 Crinos Industria Farmaco Medikamente für das fibrinolytische System

Also Published As

Publication number Publication date
JPS60188323A (ja) 1985-09-25
DE3505359C2 (de) 1994-01-20
EP0152148A3 (en) 1987-04-29
DE3505359A1 (de) 1985-08-22
US4693995A (en) 1987-09-15
AU585495B2 (en) 1989-06-22
IT1206341B (it) 1989-04-14
IT8419645A0 (it) 1984-02-16
AU3878785A (en) 1985-08-22
JPH0649651B2 (ja) 1994-06-29
EP0152148A2 (fr) 1985-08-21
EP0152148B1 (fr) 1992-05-20
ATE76296T1 (de) 1992-06-15
CH662509A5 (it) 1987-10-15

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: CRINOS INDUSTRIA FARMACOBIOLOGICA S.P.A.

Effective date: 19980228