IT8419645A0 - Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio. - Google Patents

Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio.

Info

Publication number
IT8419645A0
IT8419645A0 IT8419645A IT1964584A IT8419645A0 IT 8419645 A0 IT8419645 A0 IT 8419645A0 IT 8419645 A IT8419645 A IT 8419645A IT 1964584 A IT1964584 A IT 1964584A IT 8419645 A0 IT8419645 A0 IT 8419645A0
Authority
IT
Italy
Prior art keywords
treatment
pharmaceutical composition
myocardial ischemia
acute myocardial
acute
Prior art date
Application number
IT8419645A
Other languages
English (en)
Other versions
IT1206341B (it
Inventor
Giuseppe Primo
Marisa Mantovani
Riccardo Niada
Original Assignee
Crinos Industria Farmaco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crinos Industria Farmaco filed Critical Crinos Industria Farmaco
Publication of IT8419645A0 publication Critical patent/IT8419645A0/it
Priority to IT8419645A priority Critical patent/IT1206341B/it
Priority to AT85200159T priority patent/ATE76296T1/de
Priority to EP85200159A priority patent/EP0152148B1/en
Priority to US06/701,695 priority patent/US4693995A/en
Priority to BE0/214518A priority patent/BE901737A/fr
Priority to DE3505359A priority patent/DE3505359C2/de
Priority to JP60029218A priority patent/JPH0649651B2/ja
Priority to CH722/85A priority patent/CH662509A5/it
Priority to AU38787/85A priority patent/AU585495B2/en
Application granted granted Critical
Publication of IT1206341B publication Critical patent/IT1206341B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
IT8419645A 1984-02-16 1984-02-16 Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio. IT1206341B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT8419645A IT1206341B (it) 1984-02-16 1984-02-16 Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio.
AT85200159T ATE76296T1 (de) 1984-02-16 1985-02-11 Pharmazeutische zusammensetzung zur behandlung von akuter myocardischer ischaemie.
EP85200159A EP0152148B1 (en) 1984-02-16 1985-02-11 Pharmaceutica composition for the treatment of acute myocardial ischemia
BE0/214518A BE901737A (fr) 1984-02-16 1985-02-14 Composition pharmaceutique pour le traitement de l'ischemie myocardique aigue.
US06/701,695 US4693995A (en) 1984-02-16 1985-02-14 Pharmaceutical composition for the treatment of acute myocardial ischemia
DE3505359A DE3505359C2 (de) 1984-02-16 1985-02-15 Verwendung von Defibrotid zur Behandlung von akuter myocardialer Ischämie
JP60029218A JPH0649651B2 (ja) 1984-02-16 1985-02-15 心筋虚血治療用医薬組成物
CH722/85A CH662509A5 (it) 1984-02-16 1985-02-15 Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio.
AU38787/85A AU585495B2 (en) 1984-02-16 1985-02-15 Pharmaceutical composition for the treatment of acute myocardial ischemia

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8419645A IT1206341B (it) 1984-02-16 1984-02-16 Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio.

Publications (2)

Publication Number Publication Date
IT8419645A0 true IT8419645A0 (it) 1984-02-16
IT1206341B IT1206341B (it) 1989-04-14

Family

ID=11160049

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8419645A IT1206341B (it) 1984-02-16 1984-02-16 Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio.

Country Status (9)

Country Link
US (1) US4693995A (it)
EP (1) EP0152148B1 (it)
JP (1) JPH0649651B2 (it)
AT (1) ATE76296T1 (it)
AU (1) AU585495B2 (it)
BE (1) BE901737A (it)
CH (1) CH662509A5 (it)
DE (1) DE3505359C2 (it)
IT (1) IT1206341B (it)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1170214B (it) * 1983-09-12 1987-06-03 Crinos Industria Farmaco Composizione farmaceutica per la cura delle arteriopatie periferiche
IT1190313B (it) * 1986-04-17 1988-02-16 Crinos Industria Farmaco Procedimento per l'ottenimento di polidesossiribonucleotidi chimicamente definiti e riproducibili e prodotto farmacologicamente attivo risultante
EP0290496B2 (en) * 1986-10-06 1995-12-20 The University Of Virginia Alumni Patents Foundation Use of an adenosine, hypoxanthine and ribose-containing solution for improved protection of the heart during surgery
IT1223322B (it) * 1987-10-23 1990-09-19 Crinos Industria Farmaco Metodo per prevenire la formazione di coaguli sanguigni nel circuito extracorporeo di apparecchi di dialisi a composizione utile per esso
IT1231509B (it) * 1989-09-07 1991-12-07 Crinos Industria Farmaco Composizione farmceutica ad uso topico per la terapia della fragilita' capillare.
US5624912A (en) * 1991-08-21 1997-04-29 Burcoglu; Arsinur Method of treating HIV infection and related secondary infections with defibrotide
US5977083A (en) * 1991-08-21 1999-11-02 Burcoglu; Arsinur Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states
US6699985B2 (en) 1991-08-21 2004-03-02 Arsinur Burcoglu Method of treating HIV infection and related secondary infections thereof
IT1252174B (it) * 1991-12-09 1995-06-05 Crinos Industria Farmaco Oligodesossimibonucleotidi ad attivita' antiischemica e procedimenti per il loro ottenimento
EP0678029A1 (en) * 1993-01-13 1995-10-25 BURCOGLU, Arsinur Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states
US5852000A (en) * 1993-08-25 1998-12-22 Otsuka Pharmaceutical Factory, Inc. Cardiac rehabilitation agent
JP3057295B2 (ja) * 1993-08-25 2000-06-26 株式会社大塚製薬工場 心機能回復剤
CA2259041A1 (en) * 1997-04-28 1998-11-05 Arsinur Burcoglu Method of treating hiv infection and related secondary infections thereof
US7252818B2 (en) * 1998-07-24 2007-08-07 Cardiovascular Biotherapeutics, Inc. Method of producing biologically active human acidic fibroblast growth factor and its use in promoting angiogenesis
EP1147777A1 (en) 2000-04-18 2001-10-24 Crinos Industria Farmacobiologica S.p.A. Combination of defibrotide and G-CSF and its use to activate haematopoietic progenitors
EP1325962A1 (en) * 2001-12-17 2003-07-09 Gentium S.p.A. A method for determining the biological activity of defibrotide
EP1495702A1 (fr) 2003-07-10 2005-01-12 Nestec S.A. Dispositif pour l'extraction d'une capsule
ITMI20031714A1 (it) * 2003-09-05 2005-03-06 Gentium Spa Formazioni ad azione antitumorale.
EP1855697A2 (en) * 2005-03-03 2007-11-21 Gentium Spa Oligodeoxyribonucleotides of 4000-10000 dalton for treating tumors
EP1872787A1 (en) * 2006-06-27 2008-01-02 Gentium S.p.A. Use of defibrotide for the inhibition of heparanase
EP1982722A1 (en) * 2007-04-16 2008-10-22 Gentium S.p.A. Use of oligotide for the treatment of renal diseases
EP2103689A1 (en) 2008-03-19 2009-09-23 Gentium S.p.A. Synthetic phosphodiester oligonucleotides and therapeutical uses thereof
IT1406068B1 (it) 2010-07-22 2014-02-06 Medestea Int Spa Polidesossiribonucleotidi (pdrn) per l'impiego nel trattamento di condizioni di acidosi e composizioni a base di polidesossiribonucleotidi per il suddetto impiego
DE102010039631A1 (de) 2010-08-22 2012-02-23 Ulrich Schubert Pharmazeutische Zusammensetzungen mit immunmodulatorischen Eigenschaften
EP2637672B1 (en) 2010-11-12 2018-08-22 Gentium S.r.l. Defibrotide for use in prophylaxis and/or treatment of graft versus host disease (gvhd).
KR102038357B1 (ko) 2012-06-22 2019-10-31 젠티엄 에스알엘 디파이브로타이드의 생물학적 활성 측정을 위한 유우글로불린에 기초한 방법
EP3026122A1 (en) 2014-11-27 2016-06-01 Gentium S.p.A. Cellular-based method for determining the potency of defibrotide
EP3661484A1 (en) 2017-08-03 2020-06-10 Jazz Pharmaceuticals Ireland Limited Formulations comprising a nucleic acid in a high concentration
WO2019200251A1 (en) 2018-04-12 2019-10-17 Jazz Pharmaceuticals, Inc. Defibrotide for the prevention and treatment of cytokine release syndrome and neurotoxicity associated with immunodepletion
WO2020118165A1 (en) 2018-12-07 2020-06-11 Jazz Pharmaceuticals Ireland Limited Subcutaneous delivery of high concentration formulations
US20230190783A1 (en) 2020-02-28 2023-06-22 Jazz Pharmaceuticals Ireland Limited Delivery of low viscosity formulations
US20230086833A1 (en) 2020-04-17 2023-03-23 Jazz Pharmaceuticals Ireland Limited Defibrotide treatment for the prevention of organ rejection and injury
TW202308659A (zh) 2021-05-06 2023-03-01 愛爾蘭商爵士製藥愛爾蘭有限責任公司 用於急性呼吸窘迫症候群之治療及預防的去纖維蛋白多核苷酸

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2154279A1 (de) * 1970-11-03 1972-05-25 Crinos Industria Farmaco Medikamente für das fibrinolytische System
IT1043823B (it) * 1970-11-03 1980-02-29 Prephar Procedimento per l estrazione di acidi nucleici da organi animali
US3899481A (en) * 1970-11-03 1975-08-12 Crinos Industria Farmaco Process for the controlled partial degradation of deoxyribonucleic acid extracted from animal organs

Also Published As

Publication number Publication date
DE3505359A1 (de) 1985-08-22
AU585495B2 (en) 1989-06-22
AU3878785A (en) 1985-08-22
JPH0649651B2 (ja) 1994-06-29
US4693995A (en) 1987-09-15
EP0152148B1 (en) 1992-05-20
ATE76296T1 (de) 1992-06-15
JPS60188323A (ja) 1985-09-25
BE901737A (fr) 1985-05-29
DE3505359C2 (de) 1994-01-20
IT1206341B (it) 1989-04-14
EP0152148A2 (en) 1985-08-21
CH662509A5 (it) 1987-10-15
EP0152148A3 (en) 1987-04-29

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950404