BG108019A - Parenteral formulation containing epothilone analogs - Google Patents

Parenteral formulation containing epothilone analogs

Info

Publication number: BG108019A
Authority: BG; Bulgaria
Prior art keywords: vial; diluent; analog; epothilone; mixture
Prior art date: 2001-01-25

Application number

BG108019A

Other languages

Bulgarian (bg)

English (en)

Inventor

Rebanta Bandyopadhyay

Timothy M. Malloy

Andrea Panaggio

Krishnaswamy S. Raghavan

Sailesh A. Varia

Original Assignee

Bristol-Myers Squibb Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-01-25

Filing date

2003-07-22

Publication date

2004-09-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23005123&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BG108019(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-07-22 Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company

2004-09-30 Publication of BG108019A publication Critical patent/BG108019A/xx

Links

229930013356 epothilone Natural products 0.000 title abstract 4
150000003883 epothilone derivatives Chemical class 0.000 title abstract 4
239000000203 mixture Substances 0.000 title abstract 3
238000009472 formulation Methods 0.000 title 1
239000003085 diluting agent Substances 0.000 abstract 3
239000000243 solution Substances 0.000 abstract 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
239000008156 Ringer's lactate solution Substances 0.000 abstract 1
DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical compound CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 abstract 1
BPKIGYQJPYCAOW-FFJTTWKXSA-I calcium;potassium;disodium;(2s)-2-hydroxypropanoate;dichloride;dihydroxide;hydrate Chemical group O.[OH-].[OH-].[Na+].[Na+].[Cl-].[Cl-].[K+].[Ca+2].C[C@H](O)C([O-])=O BPKIGYQJPYCAOW-FFJTTWKXSA-I 0.000 abstract 1
238000010253 intravenous injection Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000002736 nonionic surfactant Substances 0.000 abstract 1
238000007911 parenteral administration Methods 0.000 abstract 1
239000008389 polyethoxylated castor oil Substances 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
239000004094 surface-active agent Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oil, Petroleum & Natural Gas (AREA)
Dermatology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

BG108019A 2001-01-25 2003-07-22 Parenteral formulation containing epothilone analogs BG108019A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US26422801P	2001-01-25	2001-01-25
PCT/US2002/001102 WO2002062338A1 (en)	2001-01-25	2002-01-16	Parenteral formulation containing epothilone analogs

Publications (1)

Publication Number	Publication Date
BG108019A true BG108019A (en)	2004-09-30

Family

ID=23005123

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG108019A BG108019A (en)	2001-01-25	2003-07-22	Parenteral formulation containing epothilone analogs

Country Status (24)

Country	Link
US (5)	US7022330B2 (es)
EP (1)	EP1353667A1 (es)
JP (1)	JP2004521122A (es)
KR (1)	KR20030071853A (es)
CN (2)	CN1489466A (es)
AR (2)	AR032408A1 (es)
BG (1)	BG108019A (es)
BR (1)	BR0206511A (es)
CA (2)	CA2434566A1 (es)
CZ (1)	CZ20032022A3 (es)
EE (1)	EE200300323A (es)
HU (1)	HUP0302567A2 (es)
IL (1)	IL156580A0 (es)
IS (1)	IS6890A (es)
MX (1)	MXPA03006485A (es)
NO (1)	NO20033342L (es)
PE (1)	PE20020733A1 (es)
PL (1)	PL367260A1 (es)
RU (1)	RU2003126171A (es)
SI (1)	SI1353668T1 (es)
SK (1)	SK8552003A3 (es)
UY (1)	UY27134A1 (es)
WO (1)	WO2002062338A1 (es)
ZA (3)	ZA200305126B (es)

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2002
- 2002-01-16 EE EEP200300323A patent/EE200300323A/xx unknown
- 2002-01-16 WO PCT/US2002/001102 patent/WO2002062338A1/en not_active Ceased
- 2002-01-16 BR BR0206511-8A patent/BR0206511A/pt not_active Application Discontinuation
- 2002-01-16 SK SK855-2003A patent/SK8552003A3/sk unknown
- 2002-01-16 EP EP02709040A patent/EP1353667A1/en not_active Withdrawn
- 2002-01-16 IL IL15658002A patent/IL156580A0/xx unknown
- 2002-01-16 KR KR10-2003-7009824A patent/KR20030071853A/ko not_active Withdrawn
- 2002-01-16 JP JP2002562345A patent/JP2004521122A/ja active Pending
- 2002-01-16 MX MXPA03006485A patent/MXPA03006485A/es unknown
- 2002-01-16 CN CNA028041798A patent/CN1489466A/zh active Pending
- 2002-01-16 RU RU2003126171/15A patent/RU2003126171A/ru not_active Application Discontinuation
- 2002-01-16 PL PL02367260A patent/PL367260A1/xx not_active Application Discontinuation
- 2002-01-16 HU HU0302567A patent/HUP0302567A2/hu unknown
- 2002-01-16 CZ CZ20032022A patent/CZ20032022A3/cs unknown
- 2002-01-16 CA CA002434566A patent/CA2434566A1/en not_active Abandoned
- 2002-01-17 US US10/051,727 patent/US7022330B2/en not_active Expired - Lifetime
- 2002-01-22 CA CA2681962A patent/CA2681962C/en not_active Expired - Lifetime
- 2002-01-22 SI SI200230687T patent/SI1353668T1/sl unknown
- 2002-01-22 CN CN2007101422373A patent/CN101112373B/zh not_active Expired - Fee Related
- 2002-01-25 PE PE2002000060A patent/PE20020733A1/es not_active Application Discontinuation
- 2002-01-25 UY UY27134A patent/UY27134A1/es not_active Application Discontinuation
- 2002-01-25 AR ARP020100286A patent/AR032408A1/es unknown
2003
- 2003-07-01 ZA ZA200305126A patent/ZA200305126B/xx unknown
- 2003-07-01 ZA ZA200305123A patent/ZA200305123B/en unknown
- 2003-07-17 ZA ZA200305536A patent/ZA200305536B/en unknown
- 2003-07-22 BG BG108019A patent/BG108019A/xx unknown
- 2003-07-24 NO NO20033342A patent/NO20033342L/no not_active Application Discontinuation
- 2003-07-24 IS IS6890A patent/IS6890A/is unknown
2005
- 2005-09-14 US US11/226,017 patent/US20060013836A1/en not_active Abandoned
2008
- 2008-11-04 US US12/264,375 patent/US8632788B2/en not_active Expired - Fee Related
2013
- 2013-12-19 US US14/134,172 patent/US20140107169A1/en not_active Abandoned
2014
- 2014-10-17 AR ARP140103915A patent/AR098109A2/es unknown
2015
- 2015-04-14 US US14/686,005 patent/US20150218179A1/en not_active Abandoned

Also Published As

Publication number	Publication date
ZA200305536B (en)	2004-09-06
BR0206511A (pt)	2003-10-21
PE20020733A1 (es)	2002-08-11
CA2681962A1 (en)	2002-08-01
PL367260A1 (en)	2005-02-21
ZA200305123B (en)	2004-10-01
EE200300323A (et)	2003-10-15
CN101112373A (zh)	2008-01-30
WO2002062338A1 (en)	2002-08-15
MXPA03006485A (es)	2003-09-22
AR032408A1 (es)	2003-11-05
NO20033342L (no)	2003-09-22
HUP0302567A2 (hu)	2003-12-29
RU2003126171A (ru)	2005-02-27
CN1489466A (zh)	2004-04-14
US20140107169A1 (en)	2014-04-17
IS6890A (is)	2003-07-24
SK8552003A3 (en)	2004-06-08
JP2004521122A (ja)	2004-07-15
CA2434566A1 (en)	2002-08-15
US20090069393A1 (en)	2009-03-12
AR098109A2 (es)	2016-05-04
US20150218179A1 (en)	2015-08-06
KR20030071853A (ko)	2003-09-06
US20060013836A1 (en)	2006-01-19
ZA200305126B (en)	2004-10-01
US8632788B2 (en)	2014-01-21
UY27134A1 (es)	2002-08-30
EP1353667A1 (en)	2003-10-22
CN101112373B (zh)	2012-06-20
NO20033342D0 (no)	2003-07-24
CA2681962C (en)	2012-06-12
IL156580A0 (en)	2004-01-04
US20020143038A1 (en)	2002-10-03
CZ20032022A3 (cs)	2004-04-14
US7022330B2 (en)	2006-04-04
SI1353668T1 (sl)	2008-08-31

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