BG61265B1 - Improved method for synthesis - Google Patents

Improved method for synthesis Download PDF

Info

Publication number
BG61265B1
BG61265B1 BG97146A BG9714692A BG61265B1 BG 61265 B1 BG61265 B1 BG 61265B1 BG 97146 A BG97146 A BG 97146A BG 9714692 A BG9714692 A BG 9714692A BG 61265 B1 BG61265 B1 BG 61265B1
Authority
BG
Bulgaria
Prior art keywords
omeprazole
methoxy
reaction mixture
aqueous phase
composition
Prior art date
Application number
BG97146A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG97146A (bg
Inventor
Arne E Braendstroem
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of BG97146A publication Critical patent/BG97146A/bg
Publication of BG61265B1 publication Critical patent/BG61265B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
BG97146A 1990-06-07 1992-12-04 Improved method for synthesis BG61265B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9002043A SE9002043D0 (sv) 1990-06-07 1990-06-07 Improved method for synthesis
PCT/SE1991/000402 WO1991018895A1 (fr) 1990-06-07 1991-06-05 Procede de synthese ameliore

Publications (2)

Publication Number Publication Date
BG97146A BG97146A (bg) 1993-12-24
BG61265B1 true BG61265B1 (en) 1997-04-30

Family

ID=20379708

Family Applications (1)

Application Number Title Priority Date Filing Date
BG97146A BG61265B1 (en) 1990-06-07 1992-12-04 Improved method for synthesis

Country Status (42)

Country Link
US (1) US5386032A (fr)
EP (1) EP0533752B1 (fr)
JP (1) JP2993122B2 (fr)
KR (1) KR0178045B1 (fr)
CN (1) CN1040536C (fr)
AP (1) AP216A (fr)
AT (1) ATE162790T1 (fr)
AU (1) AU640246B2 (fr)
BG (1) BG61265B1 (fr)
CA (1) CA2083605C (fr)
CZ (1) CZ279928B6 (fr)
DE (1) DE69128832T2 (fr)
DK (1) DK0533752T3 (fr)
DZ (1) DZ1504A1 (fr)
EG (1) EG19392A (fr)
ES (1) ES2113378T3 (fr)
FI (1) FI102967B (fr)
GR (1) GR3026642T3 (fr)
HK (1) HK1003831A1 (fr)
HR (1) HRP920770B1 (fr)
HU (1) HU214323B (fr)
IE (1) IE911845A1 (fr)
IL (1) IL98274A (fr)
IS (1) IS1752B (fr)
LT (1) LT3584B (fr)
LV (1) LV10271B (fr)
MA (1) MA22171A1 (fr)
NO (1) NO300541B1 (fr)
NZ (1) NZ238224A (fr)
PL (1) PL165433B1 (fr)
PT (1) PT97873B (fr)
RO (1) RO111366B1 (fr)
RU (1) RU2061693C1 (fr)
SA (1) SA91120027B1 (fr)
SE (1) SE9002043D0 (fr)
SG (1) SG48053A1 (fr)
SK (1) SK278505B6 (fr)
TN (1) TNSN91042A1 (fr)
UA (1) UA32524C2 (fr)
WO (1) WO1991018895A1 (fr)
YU (1) YU47570B (fr)
ZA (1) ZA913779B (fr)

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US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
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SE510650C2 (sv) * 1997-05-30 1999-06-14 Astra Ab Ny förening
SE510643C2 (sv) * 1997-06-27 1999-06-14 Astra Ab Termodynamiskt stabil omeprazol natrium form B
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US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6780880B1 (en) 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
RU2247120C2 (ru) * 1999-10-28 2005-02-27 Грюненталь Гмбх Способ получения противоязвенных терапевтических средств
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US20040248942A1 (en) * 2003-02-20 2004-12-09 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CA2531564C (fr) * 2003-07-18 2016-01-19 Santarus, Inc. Formulations pharmaceutiques utilisees pour inhiber une secretion acide et procede de fabrication associe
WO2005007117A2 (fr) * 2003-07-18 2005-01-27 Santarus, Inc. Formulation pharmaceutique et procede de traitement de troubles gastro-intestinaux lies a l'acidite
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
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HUE027865T2 (en) 2005-12-01 2016-11-28 Auspex Pharmaceuticals Inc Substituted phenyl ethylamines with serotonergic and / or norepinephrine activity
EP1801110A1 (fr) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Sel d'arginine d'ésoméprazole
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WO2010134099A1 (fr) 2009-05-21 2010-11-25 Cadila Healthcare Limited Procédé de préparation dans un récipient unique d'oméprazole
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CN104203938A (zh) 2012-01-21 2014-12-10 朱比兰特生命科学有限公司 用于制备2-吡啶基甲基亚硫酰基苯并咪唑、它们的类似物和光学活性对映体的方法
TW202126317A (zh) 2019-09-24 2021-07-16 美商普拉塔生技公司 用於治療發炎和免疫疾病之組成物和方法

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Also Published As

Publication number Publication date
HRP920770A2 (en) 1995-12-31
NZ238224A (en) 1993-11-25
PL165433B1 (pl) 1994-12-30
AU8080791A (en) 1991-12-31
CN1040536C (zh) 1998-11-04
FI925529L (fi) 1992-12-04
JPH05507699A (ja) 1993-11-04
AP216A (en) 1992-09-02
NO300541B1 (no) 1997-06-16
WO1991018895A1 (fr) 1991-12-12
NO924682L (no) 1992-12-04
IS3711A7 (is) 1991-12-08
JP2993122B2 (ja) 1999-12-20
SA91120027B1 (ar) 2002-06-03
EG19392A (en) 1995-06-29
KR0178045B1 (en) 1999-03-20
HUT63408A (en) 1993-08-30
CS172691A3 (en) 1992-01-15
ATE162790T1 (de) 1998-02-15
IS1752B (is) 2000-07-21
UA32524C2 (uk) 2001-02-15
LV10271A (lv) 1994-10-20
CZ279928B6 (cs) 1995-08-16
CA2083605A1 (fr) 1991-12-08
YU99291A (sh) 1993-11-16
PT97873A (pt) 1992-04-30
HU9203855D0 (en) 1993-03-29
FI102967B1 (fi) 1999-03-31
BG97146A (bg) 1993-12-24
YU47570B (sh) 1995-10-03
SG48053A1 (en) 1998-04-17
ZA913779B (en) 1992-02-26
EP0533752B1 (fr) 1998-01-28
DK0533752T3 (da) 1998-06-02
HU214323B (hu) 1998-03-02
FI102967B (fi) 1999-03-31
LTIP1711A (en) 1995-07-25
US5386032A (en) 1995-01-31
DZ1504A1 (fr) 2004-09-13
MA22171A1 (fr) 1991-12-31
RO111366B1 (ro) 1996-09-30
HRP920770B1 (en) 2000-06-30
CA2083605C (fr) 1998-12-08
GR3026642T3 (en) 1998-07-31
EP0533752A1 (fr) 1993-03-31
DE69128832D1 (de) 1998-03-05
LT3584B (en) 1995-12-27
SE9002043D0 (sv) 1990-06-07
NO924682D0 (no) 1992-12-04
DE69128832T2 (de) 1998-05-28
AU640246B2 (en) 1993-08-19
IE911845A1 (en) 1991-12-18
FI925529A0 (fi) 1992-12-04
SK278505B6 (en) 1997-08-06
HK1003831A1 (en) 1998-11-06
CN1058211A (zh) 1992-01-29
LV10271B (en) 1995-04-20
RU2061693C1 (ru) 1996-06-10
PT97873B (pt) 1998-10-30
IL98274A (en) 1995-03-30
TNSN91042A1 (fr) 1992-10-25
AP9100274A0 (en) 1991-07-31
ES2113378T3 (es) 1998-05-01
IL98274A0 (en) 1992-06-21

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