ATE443051T1 - Verfahren zur herstellung substituierter sulfoxide - Google Patents
Verfahren zur herstellung substituierter sulfoxideInfo
- Publication number
- ATE443051T1 ATE443051T1 AT05790107T AT05790107T ATE443051T1 AT E443051 T1 ATE443051 T1 AT E443051T1 AT 05790107 T AT05790107 T AT 05790107T AT 05790107 T AT05790107 T AT 05790107T AT E443051 T1 ATE443051 T1 AT E443051T1
- Authority
- AT
- Austria
- Prior art keywords
- compound
- formula
- producing substituted
- substituted sulfoxides
- substituted pyridinylmethyl
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000003462 sulfoxides Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- HBDKFZNDMVLSHM-UHFFFAOYSA-N 2-(pyridin-2-ylmethylsulfinyl)-1h-benzimidazole Chemical class N=1C2=CC=CC=C2NC=1S(=O)CC1=CC=CC=N1 HBDKFZNDMVLSHM-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 125000006513 pyridinyl methyl group Chemical group 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 150000003568 thioethers Chemical class 0.000 abstract 1
- 229910052723 transition metal Inorganic materials 0.000 abstract 1
- 150000003624 transition metals Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1957DE2004 | 2004-10-11 | ||
| PCT/IB2005/002946 WO2006040635A1 (en) | 2004-10-11 | 2005-10-04 | Processes for the preparation of substituted sulfoxides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE443051T1 true ATE443051T1 (de) | 2009-10-15 |
Family
ID=35332342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05790107T ATE443051T1 (de) | 2004-10-11 | 2005-10-04 | Verfahren zur herstellung substituierter sulfoxide |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7915422B2 (de) |
| EP (1) | EP1802584B1 (de) |
| AT (1) | ATE443051T1 (de) |
| DE (1) | DE602005016705D1 (de) |
| PL (1) | PL1802584T3 (de) |
| SI (1) | SI1802584T1 (de) |
| WO (1) | WO2006040635A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7683177B2 (en) | 2003-06-10 | 2010-03-23 | Teva Pharmaceutical Industries Ltd | Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole |
| US7579476B2 (en) * | 2006-02-24 | 2009-08-25 | Praktikatalyst Pharma, Llc | Transition metal mediated oxidation of hetero atoms in organic molecules coordinated to transition metals |
| WO2008004245A1 (en) * | 2006-07-05 | 2008-01-10 | Lupin Limited | Process for the preparation of optically pure or optically enriched enantiomers of sulphoxide compounds |
| US8173818B2 (en) | 2006-08-08 | 2012-05-08 | Jubilant Organosys Limited | Process for producing sulphoxide compounds |
| WO2008102145A2 (en) * | 2007-02-21 | 2008-08-28 | Cipla Limited | Process for the preparation of esomeprazole magnesium dihydrate |
| WO2009040825A1 (en) * | 2007-09-25 | 2009-04-02 | Hetero Drugs Limited | A process for preparation of enantiomerically pure esomeprazole |
| WO2009066321A2 (en) * | 2007-10-03 | 2009-05-28 | Ipca Laboratories Limited | Process for optically active sulfoxide compounds |
| KR101001646B1 (ko) | 2008-12-12 | 2010-12-17 | 한미약품 주식회사 | (ｒ)-(+)-란소프라졸의 제조방법 및 이에 사용되는 중간체 |
| BR112012001078A8 (pt) | 2009-07-16 | 2016-05-03 | Bayer Cropscience Ag | Processo para preparação de derivados de sulfóxido de 3-triazolila quirais |
| EP2980086B1 (de) | 2014-07-29 | 2016-06-15 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Effizientes Verfahren zur Herstellung von Esomeprazol (S)-Binol Komplex |
| EP3064495B1 (de) | 2015-03-06 | 2016-12-14 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Verbessertes verfahren zur herstellung von optisch reinen esomeprazole |
| CN108623564B (zh) * | 2017-03-17 | 2022-11-04 | 江苏豪森药业集团有限公司 | 一种雷贝拉唑类似物的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9002043D0 (sv) | 1990-06-07 | 1990-06-07 | Astra Ab | Improved method for synthesis |
| SE504459C2 (sv) * | 1994-07-15 | 1997-02-17 | Astra Ab | Förfarande för framställning av substituerade sulfoxider |
| SK283805B6 (sk) | 1996-09-09 | 2004-02-03 | Slovakofarma, A. S. | Spôsob prípravy omeprazolu |
| SE9704183D0 (sv) * | 1997-11-14 | 1997-11-14 | Astra Ab | New process |
| GB9805558D0 (en) | 1998-03-17 | 1998-05-13 | Knoll Ag | Chemical process` |
| SI20019A (sl) | 1998-07-13 | 2000-02-29 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola |
| US6166213A (en) | 1998-08-11 | 2000-12-26 | Merck & Co., Inc. | Omeprazole process and compositions thereof |
| US6303009B1 (en) * | 1999-11-15 | 2001-10-16 | Peter R. Bossard | Hydrogen generator with feedback control |
| ES2163372B1 (es) | 2000-03-13 | 2003-05-01 | Esteve Quimica Sa | Procedimiento de oxidacion de un grupo tioeter a sulfoxido. |
| KR100775802B1 (ko) | 2000-04-28 | 2007-11-12 | 다케다 야쿠힌 고교 가부시키가이샤 | 광학 활성 술폭시드 유도체의 제조 방법 |
| AU2003262375A1 (en) | 2002-04-22 | 2003-11-03 | Sun Pharmaceutical Industries Limited | Optically active substituted pyridinylmethyl-sulphinyl-benzimidazole and salts |
-
2005
- 2005-10-04 US US11/576,867 patent/US7915422B2/en not_active Expired - Fee Related
- 2005-10-04 WO PCT/IB2005/002946 patent/WO2006040635A1/en not_active Ceased
- 2005-10-04 DE DE602005016705T patent/DE602005016705D1/de not_active Expired - Lifetime
- 2005-10-04 SI SI200530787T patent/SI1802584T1/sl unknown
- 2005-10-04 AT AT05790107T patent/ATE443051T1/de not_active IP Right Cessation
- 2005-10-04 PL PL05790107T patent/PL1802584T3/pl unknown
- 2005-10-04 EP EP05790107A patent/EP1802584B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1802584A1 (de) | 2007-07-04 |
| US20080275245A1 (en) | 2008-11-06 |
| US7915422B2 (en) | 2011-03-29 |
| SI1802584T1 (sl) | 2010-01-29 |
| DE602005016705D1 (de) | 2009-10-29 |
| WO2006040635A1 (en) | 2006-04-20 |
| PL1802584T3 (pl) | 2010-03-31 |
| EP1802584B1 (de) | 2009-09-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |