BG94934A - Твърди лекарствени форми за орално приложение,съдържащи ифосфамид като активно вещество - Google Patents

Твърди лекарствени форми за орално приложение,съдържащи ифосфамид като активно вещество

Info

Publication number
BG94934A
BG94934A BG094934A BG9493491A BG94934A BG 94934 A BG94934 A BG 94934A BG 094934 A BG094934 A BG 094934A BG 9493491 A BG9493491 A BG 9493491A BG 94934 A BG94934 A BG 94934A
Authority
BG
Bulgaria
Prior art keywords
oral administration
active substance
ifosphamide
administration containing
ifosfamide
Prior art date
Application number
BG094934A
Other languages
English (en)
Other versions
BG60900B1 (bg
Inventor
Dieter Sauerbier
Juergen Engel
Eckhard Milsmann
Klaus Molge
Otto Isaac
Original Assignee
Asta Medica Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Aktiengesellschaft filed Critical Asta Medica Aktiengesellschaft
Publication of BG94934A publication Critical patent/BG94934A/bg
Publication of BG60900B1 publication Critical patent/BG60900B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Твърдите лекарствени форми с ифосфамид за орално приложение съдържат маса от активното вещество ифосфамид и микрокристалинна целулоза. Когато са на таблетки, отнесено към 1 тегл.ч. ифосфамид, те съдържат 0,1-1,0 тегл.ч. трикалциев фосфат и 0,04-0,4 тегл.ч. полиетиленгликол. Допълнително към теглото на таблетката се прибавят в тегл.% От 5 до 60 пълнител и средство за регулиране на течливостта, от 1 до 10 разпадащо вещество, от 0,1 до 10 противозалепващо средство и от 0,1 до 80 свързващо вещество. 2 претенции
BG94934A 1990-08-03 1991-08-01 Твърди лекарствени форми за орално приложение,съдържащи ифосфамид като активно вещество BG60900B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4024683 1990-08-03
SG181694A SG181694G (en) 1990-08-03 1994-12-30 Solid oral administration forms containing ifosfamide as active agent

Publications (2)

Publication Number Publication Date
BG94934A true BG94934A (bg) 1993-12-24
BG60900B1 BG60900B1 (bg) 1996-06-28

Family

ID=25895607

Family Applications (1)

Application Number Title Priority Date Filing Date
BG94934A BG60900B1 (bg) 1990-08-03 1991-08-01 Твърди лекарствени форми за орално приложение,съдържащи ифосфамид като активно вещество

Country Status (33)

Country Link
US (1) US5158776A (bg)
EP (1) EP0469440B1 (bg)
JP (2) JP3061898B2 (bg)
KR (1) KR0177170B1 (bg)
CN (1) CN1046851C (bg)
AR (1) AR247484A1 (bg)
AT (1) ATE110261T1 (bg)
AU (2) AU643309B2 (bg)
BG (1) BG60900B1 (bg)
CA (1) CA2048367C (bg)
CZ (1) CZ280475B6 (bg)
DE (2) DE4124481A1 (bg)
DK (1) DK0469440T3 (bg)
EG (1) EG19690A (bg)
ES (1) ES2058999T3 (bg)
FI (1) FI97951C (bg)
HK (1) HK15695A (bg)
HR (1) HRP920575B1 (bg)
HU (1) HU206268B (bg)
IE (1) IE66378B1 (bg)
IL (1) IL99031A (bg)
LT (1) LT3528B (bg)
LV (1) LV10043B (bg)
MC (1) MC2274A1 (bg)
MX (1) MX9100441A (bg)
NO (1) NO178252C (bg)
NZ (1) NZ239222A (bg)
PT (1) PT98532B (bg)
RO (1) RO113611B1 (bg)
SG (1) SG181694G (bg)
SI (1) SI9111342B (bg)
SK (2) SK279740B6 (bg)
ZA (1) ZA916124B (bg)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996010996A1 (en) * 1993-07-21 1996-04-18 The University Of Kentucky Research Foundation A multicompartment hard capsule with control release properties
ITFI970184A1 (it) * 1997-07-30 1999-01-30 Menarini Farma Ind Composizioni farmaceutiche contenenti vitamina d e calcio,loro preparazione ed uso terapeutico
DE19733305A1 (de) * 1997-08-01 1999-02-04 Asta Medica Ag Pharmazeutische Zusammensetzung enthaltend Ifosfamid und Carnitin
US6103297A (en) * 1998-01-14 2000-08-15 Matsushita Electronics Corporation Method of manufacturing cathode-ray tube
DE19826517B4 (de) * 1998-06-15 2006-03-23 Baxter Healthcare S.A. Verfahren zur Herstellung von Filmtabletten mit Cyclophosphamid als Wirkstoff und daraus hergestellte Cyclophosphamid-Filmtablette
US20040253307A1 (en) * 2003-02-04 2004-12-16 Brian Hague Sugar-free oral transmucosal solid dosage forms and uses thereof
DE102005008797A1 (de) * 2005-02-25 2006-09-07 Baxter International Inc., Deerfield Trofosfamid-haltige Filmtabletten und Verfahren zu deren Herstellung
CN114010629A (zh) 2014-01-06 2022-02-08 英国神盾Tx股份有限公司 三麦芽酚铁的剂量方案
GB201418710D0 (en) 2014-10-21 2014-12-03 Iron Therapeutics Holdings Ag Dosage regimen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3987204A (en) 1972-09-15 1976-10-19 Sucrest Corporation Direct compression vehicle
JPS5646807A (en) * 1979-09-27 1981-04-28 Japan Atom Energy Res Inst Production of composition of complex gradually releasing physiologically active substance
DE3111428A1 (de) * 1981-03-24 1982-10-07 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
US4618692A (en) * 1981-09-03 1986-10-21 Asta-Werke Aktiengesellschaft 4-carbamoyloxy-oxazaphosphorins
US5019385A (en) * 1984-11-09 1991-05-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Novel lymphopine LK 2 and pharmaceutic compositions containing same
EP0254902B1 (de) * 1986-07-11 1991-08-28 ASTA Pharma Aktiengesellschaft Lösungen von Oxazaphosphorinen mit verbesserter Stabilität und Verfahren zu deren Herstellung
DE3804686A1 (de) * 1988-02-15 1989-08-24 Henkel Kgaa Arzneimittel mit einer kombination von cytostatika bzw. hormontherapeutika und phosphonoderivaten

Also Published As

Publication number Publication date
IE912774A1 (en) 1992-02-12
CN1058715A (zh) 1992-02-19
JP3061898B2 (ja) 2000-07-10
DK0469440T3 (da) 1994-11-14
KR920003963A (ko) 1992-03-27
HRP920575A2 (en) 1995-04-30
NO178252C (no) 1996-02-21
JP3545300B2 (ja) 2004-07-21
IL99031A (en) 1996-09-04
CA2048367C (en) 2000-05-23
MC2274A1 (fr) 1993-06-23
FI913710L (fi) 1992-02-04
LTIP921A (en) 1995-03-27
HK15695A (en) 1995-02-10
JP2000229860A (ja) 2000-08-22
FI913710A0 (fi) 1991-08-02
NO178252B (no) 1995-11-13
NO913019D0 (no) 1991-08-02
AU643309B2 (en) 1993-11-11
DE4124481A1 (de) 1992-02-06
HUT59316A (en) 1992-05-28
ES2058999T3 (es) 1994-11-01
EP0469440A1 (de) 1992-02-05
ZA916124B (en) 1992-04-29
FI97951C (fi) 1997-03-25
AU649184B2 (en) 1994-05-12
LV10043B (en) 1995-06-20
ATE110261T1 (de) 1994-09-15
CA2048367A1 (en) 1992-02-04
SI9111342B (sl) 1998-10-31
SK279740B6 (sk) 1999-03-12
SG181694G (en) 1995-05-12
LV10043A (lv) 1994-05-10
AR247484A1 (es) 1995-01-31
EG19690A (en) 1995-09-30
AU8158991A (en) 1992-02-06
HU206268B (en) 1992-10-28
BG60900B1 (bg) 1996-06-28
CS240991A3 (en) 1992-03-18
PT98532A (pt) 1992-06-30
RO113611B1 (ro) 1998-09-30
SI9111342A (sl) 1998-04-30
JPH04243828A (ja) 1992-08-31
CN1046851C (zh) 1999-12-01
IL99031A0 (en) 1992-07-15
MX9100441A (es) 1992-04-01
NO913019L (no) 1992-02-04
LT3528B (en) 1995-11-27
KR0177170B1 (ko) 1999-03-20
HU912594D0 (en) 1992-01-28
DE59102620D1 (de) 1994-09-29
US5158776A (en) 1992-10-27
CZ280475B6 (cs) 1996-01-17
SK279739B6 (sk) 1999-03-12
HRP920575B1 (en) 1999-04-30
NZ239222A (en) 1993-01-27
FI97951B (fi) 1996-12-13
EP0469440B1 (de) 1994-08-24
IE66378B1 (en) 1995-12-27
PT98532B (pt) 1999-01-29
AU4483693A (en) 1993-11-11

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