BRPI0507026A - proteìnas de fusão de albumina - Google Patents

proteìnas de fusão de albumina

Info

Publication number
BRPI0507026A
BRPI0507026A BRPI0507026-0A BRPI0507026A BRPI0507026A BR PI0507026 A BRPI0507026 A BR PI0507026A BR PI0507026 A BRPI0507026 A BR PI0507026A BR PI0507026 A BRPI0507026 A BR PI0507026A
Authority
BR
Brazil
Prior art keywords
fusion proteins
albumin fusion
nucleic acids
vectors
albumin
Prior art date
Application number
BRPI0507026-0A
Other languages
English (en)
Inventor
Craig A Rosen
William A Haseltine
Paul A Moore
Jason B Bock
Adam Bell
Yanggy Shi
David Lafleur
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of BRPI0507026A publication Critical patent/BRPI0507026A/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/35—Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)

Abstract

"PROTEìNAS DE FUSãO DE ALBUMINA". A presente invenção inclui as proteína de fusão de albumina. As moléculas de ácidos nucléicos codificando as proteínas de fusão de albumina da invenção são também incluídas pela invenção, como são os vetores contendo estes ácidos nucléicos, as células hospedeiras transformadas com estes vetores com ácidos nucléicos, e os métodos de preparar as proteínas de fusão de albumina da invenção e utilizar estes ácidos nucléicos, vetores, e/ou células hospedeiras. Adicionalmente, a presente invenção inclui as composições farmacêuticas compreendendo as proteínas de fusão de albumina e os métodos de tratar, prevenir, ou melhorar as doenças, os distúrbios ou as condições usando as proteinas de fusão de albumina da invenção.
BRPI0507026-0A 2004-02-09 2005-02-09 proteìnas de fusão de albumina BRPI0507026A (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US54227404P 2004-02-09 2004-02-09
US54990104P 2004-03-05 2004-03-05
US55690604P 2004-03-29 2004-03-29
US63660304P 2004-12-17 2004-12-17
PCT/US2005/004041 WO2005077042A2 (en) 2004-02-09 2005-02-09 Albumin fusion proteins

Publications (1)

Publication Number Publication Date
BRPI0507026A true BRPI0507026A (pt) 2007-04-17

Family

ID=34865403

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0507026-0A BRPI0507026A (pt) 2004-02-09 2005-02-09 proteìnas de fusão de albumina

Country Status (20)

Country Link
US (3) US20070048282A1 (pt)
EP (1) EP1729795B1 (pt)
JP (2) JP5010923B2 (pt)
KR (1) KR101184391B1 (pt)
CN (1) CN102816241B (pt)
AU (2) AU2005211725B2 (pt)
BR (1) BRPI0507026A (pt)
CA (1) CA2554089C (pt)
CY (1) CY1117401T1 (pt)
DK (1) DK1729795T3 (pt)
ES (1) ES2567634T3 (pt)
HU (1) HUE027902T2 (pt)
IL (1) IL176894A (pt)
MA (1) MA28565B1 (pt)
MX (1) MXPA06009072A (pt)
NO (1) NO20064059L (pt)
NZ (1) NZ548612A (pt)
PL (1) PL1729795T3 (pt)
SI (1) SI1729795T1 (pt)
WO (1) WO2005077042A2 (pt)

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