BR0318250A - emplastro terapêutico com matriz de polissiloxano compreendendo capsaicina - Google Patents

emplastro terapêutico com matriz de polissiloxano compreendendo capsaicina

Info

Publication number
BR0318250A
BR0318250A BRPI0318250-9A BR0318250A BR0318250A BR 0318250 A BR0318250 A BR 0318250A BR 0318250 A BR0318250 A BR 0318250A BR 0318250 A BR0318250 A BR 0318250A
Authority
BR
Brazil
Prior art keywords
capsaicin
therapeutic compound
polysiloxane
relates
matrix
Prior art date
Application number
BRPI0318250-9A
Other languages
English (en)
Other versions
BRPI0318250B8 (pt
BRPI0318250B1 (pt
Inventor
Walter Mueller
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of BR0318250A publication Critical patent/BR0318250A/pt
Publication of BRPI0318250B1 publication Critical patent/BRPI0318250B1/pt
Publication of BRPI0318250B8 publication Critical patent/BRPI0318250B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

"EMPLASTRO TERAPêUTICO COM MATRIZ DE POLISSILOXANO COMPREENDENDO CAPSAICINA". A presente invenção refere-se a emplastro tópico contendo capsaicina ou análogo de capsaicina, processo para a sua preparação e seu uso. A invenção relaciona-se a um emplastro tópico compreendendo uma camada de apoio impermeável ao composto terapêutico, uma matriz auto-adesiva baseada em polissiloxanos e contendo capsaicina, ou um composto terapêutico análogo à capsaicina, e um filme protetor a ser removido antes do uso, em que a matriz contém microrreservatórios líquidos baseados em um solvente anfifílico, no qual o composto terapêutico está presente na forma completamente dissolvida e a concentração do composto terapêutico nas gotículas de microrreservatórios está abaixo da concentração de saturação. A invenção, além disso, relaciona-se a um processo para a sua produção e ao seu uso no tratamento de dor neuropática.
BRPI0318250A 2003-04-14 2003-11-19 emplastro tópico com matriz de polissiloxano e método para a produção de preparação de um emplastro tópico BRPI0318250B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46263003P 2003-04-14 2003-04-14
PCT/EP2003/012929 WO2004089361A1 (en) 2003-04-14 2003-11-19 Therapeutic patch with polysiloxane matrix comprising capsaicin

Publications (3)

Publication Number Publication Date
BR0318250A true BR0318250A (pt) 2006-05-23
BRPI0318250B1 BRPI0318250B1 (pt) 2015-08-11
BRPI0318250B8 BRPI0318250B8 (pt) 2021-05-25

Family

ID=33159857

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0318250A BRPI0318250B8 (pt) 2003-04-14 2003-11-19 emplastro tópico com matriz de polissiloxano e método para a produção de preparação de um emplastro tópico

Country Status (23)

Country Link
US (2) US8821920B2 (pt)
EP (1) EP1613297B1 (pt)
JP (1) JP4943657B2 (pt)
KR (1) KR101050672B1 (pt)
CN (2) CN100512806C (pt)
AT (1) ATE363900T1 (pt)
AU (1) AU2003289710B2 (pt)
BR (1) BRPI0318250B8 (pt)
CA (1) CA2517493C (pt)
CY (1) CY1106744T1 (pt)
DE (1) DE60314298T2 (pt)
DK (1) DK1613297T3 (pt)
ES (1) ES2288222T3 (pt)
IL (1) IL171249A (pt)
MX (1) MXPA05011012A (pt)
NO (1) NO337896B1 (pt)
NZ (1) NZ541956A (pt)
PL (1) PL219512B1 (pt)
PT (1) PT1613297E (pt)
RU (1) RU2349315C9 (pt)
UA (1) UA81665C2 (pt)
WO (1) WO2004089361A1 (pt)
ZA (1) ZA200506462B (pt)

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WO2015177212A1 (en) 2014-05-20 2015-11-26 Lts Lohmann Therapie-Systeme Ag Transdermal delivery system including an interface mediator
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CN104546805A (zh) * 2014-12-15 2015-04-29 刘闯 一种治疗皮肤色斑的药膏贴
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CN111093638B (zh) * 2017-09-04 2024-03-26 罗曼治疗系统股份公司 包含乳化剂的透皮递送系统
MX2022011400A (es) 2020-03-17 2022-10-13 Gruenenthal Gmbh Aplicacion topica repetida de parche de capsaicina para usarse para tratar pacientes que no responden inicialmente al tratamiento.
EP4125841A1 (en) * 2020-04-03 2023-02-08 Grünenthal GmbH Regimen for repeated topical application of capsaicin patch
TWI807338B (zh) * 2020-06-26 2023-07-01 美商美國禮來大藥廠 結合ＴＧＦ-α及表皮調節素（ＥＰＩＲＥＧＵＬＩＮ）之抗體於治療疼痛之用途
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Also Published As

Publication number Publication date
ZA200506462B (en) 2006-05-31
JP4943657B2 (ja) 2012-05-30
PL378806A1 (pl) 2006-05-15
WO2004089361A1 (en) 2004-10-21
US20140335150A1 (en) 2014-11-13
RU2005134984A (ru) 2007-05-27
JP2006514977A (ja) 2006-05-18
NO20055310L (no) 2005-11-10
KR101050672B1 (ko) 2011-07-19
ES2288222T3 (es) 2008-01-01
PT1613297E (pt) 2007-08-23
PL219512B1 (pl) 2015-05-29
AU2003289710B2 (en) 2009-07-30
KR20060002997A (ko) 2006-01-09
IL171249A (en) 2010-06-16
CY1106744T1 (el) 2012-05-23
UA81665C2 (ru) 2008-01-25
CN100512806C (zh) 2009-07-15
US20040202707A1 (en) 2004-10-14
AU2003289710A1 (en) 2004-11-01
EP1613297A1 (en) 2006-01-11
BRPI0318250B8 (pt) 2021-05-25
CN101601664B (zh) 2012-05-23
HK1090844A1 (zh) 2007-01-05
CN101601664A (zh) 2009-12-16
HK1136957A1 (en) 2010-07-16
US8821920B2 (en) 2014-09-02
DE60314298T2 (de) 2008-01-31
CA2517493A1 (en) 2004-10-21
NZ541956A (en) 2008-09-26
BRPI0318250B1 (pt) 2015-08-11
CA2517493C (en) 2011-05-31
RU2349315C2 (ru) 2009-03-20
DK1613297T3 (da) 2007-09-24
NO337896B1 (no) 2016-07-04
CN1784222A (zh) 2006-06-07
EP1613297B1 (en) 2007-06-06
DE60314298D1 (de) 2007-07-19
ATE363900T1 (de) 2007-06-15
RU2349315C9 (ru) 2010-02-27
MXPA05011012A (es) 2005-12-12

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