BR9504576A - Esteróide processo para a preparaçao do mesmo composiçao farmacêutica uso do esteróide e processo de contracepçao - Google Patents

Esteróide processo para a preparaçao do mesmo composiçao farmacêutica uso do esteróide e processo de contracepçao

Info

Publication number: BR9504576A
Authority: BR; Brazil
Prior art keywords: steroid; halogen; alkyl; optionally substituted; preparation
Prior art date: 1994-10-27

Application number

BR9504576A

Other languages

English (en)

Inventor

Johannes Antonius Mar Hamersma

Jaap Van Der Louw

Original Assignee

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-27

Filing date

1995-10-26

Publication date

1997-05-20

1995-10-26 Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv

1997-05-20 Publication of BR9504576A publication Critical patent/BR9504576A/pt

Links

150000003431 steroids Chemical class 0.000 title abstract 4
239000008194 pharmaceutical composition Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 7
229910052736 halogen Inorganic materials 0.000 abstract 6
150000002367 halogens Chemical class 0.000 abstract 6
229910052739 hydrogen Inorganic materials 0.000 abstract 3
125000002252 acyl group Chemical group 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000002070 alkenylidene group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000001118 alkylidene group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
229940124558 contraceptive agent Drugs 0.000 abstract 1
239000003433 contraceptive agent Substances 0.000 abstract 1
125000000686 lactone group Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000003884 phenylalkyl group Chemical group 0.000 abstract 1
230000001072 progestational effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0092—Alkenyl derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/001—Lactones
- C07J21/003—Lactones at position 17
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0016—Oximes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Gynecology & Obstetrics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BR9504576A 1994-10-27 1995-10-26 Esteróide processo para a preparaçao do mesmo composiçao farmacêutica uso do esteróide e processo de contracepçao BR9504576A (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP94203117		1994-10-27

Publications (1)

Publication Number	Publication Date
BR9504576A true BR9504576A (pt)	1997-05-20

Family

ID=8217314

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9504576A BR9504576A (pt)	1994-10-27	1995-10-26	Esteróide processo para a preparaçao do mesmo composiçao farmacêutica uso do esteróide e processo de contracepçao

Country Status (26)

Country	Link
US (1)	US5741786A (pt)
EP (1)	EP0709394B1 (pt)
JP (1)	JPH08225590A (pt)
KR (1)	KR100402636B1 (pt)
CN (1)	CN1052237C (pt)
AT (1)	ATE199015T1 (pt)
AU (1)	AU689642B2 (pt)
BR (1)	BR9504576A (pt)
CA (1)	CA2161490A1 (pt)
CZ (1)	CZ287346B6 (pt)
DE (1)	DE69520022T2 (pt)
DK (1)	DK0709394T3 (pt)
ES (1)	ES2157290T3 (pt)
FI (1)	FI113542B (pt)
GR (1)	GR3035713T3 (pt)
HU (1)	HU221192B1 (pt)
IL (1)	IL115659A (pt)
NO (1)	NO305252B1 (pt)
NZ (1)	NZ280325A (pt)
PL (1)	PL187083B1 (pt)
PT (1)	PT709394E (pt)
RU (1)	RU2168516C2 (pt)
SG (1)	SG33569A1 (pt)
TR (1)	TR199501327A2 (pt)
TW (1)	TW339337B (pt)
ZA (1)	ZA958963B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6407082B1 (en) *	1996-09-13	2002-06-18	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of a vitamin D compound
US6034074A (en)	1996-09-13	2000-03-07	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of a Vitamin D compound
US6511970B1 (en)	1996-09-13	2003-01-28	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US6765002B2 (en)	2000-03-21	2004-07-20	Gustavo Rodriguez	Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US6028064A (en)	1996-09-13	2000-02-22	New Life Pharmaceuticals Inc.	Prevention of ovarian cancer by administration of progestin products
DE19651000A1 (de) *	1996-12-01	1998-06-04	Schering Ag	Oxyiminopregnancarbolactone
ATE473759T1 (de)	1998-05-22	2010-07-15	Univ Leland Stanford Junior	Bifunktionelle moleküle sowie darauf basierende therapien.
US6043235A (en) *	1999-07-21	2000-03-28	Research Triangle Institute	11β-aryl-17, 17-spirothiolane-substituted steroids
US20010044431A1 (en) *	2000-03-21	2001-11-22	Rodriguez Gustavo C.	Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
AU2002322720B2 (en)	2001-07-25	2008-11-13	Raptor Pharmaceutical Inc.	Compositions and methods for modulating blood-brain barrier transport
CN102379684B (zh)	2005-04-28	2014-11-19	普罗透斯数字保健公司	药物信息系统
US9062126B2 (en)	2005-09-16	2015-06-23	Raptor Pharmaceuticals Inc.	Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
EP2398500B1 (en)	2009-02-20	2019-03-13	2-BBB Medicines B.V.	Glutathione-based drug delivery system
ES2942923T3 (es)	2009-05-06	2023-06-07	Laboratory Skin Care Inc	Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
CA3174401A1 (en) *	2020-04-03	2021-10-07	Daan De Kubber	Method of draining water

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2875199A (en) *	1958-04-22	1959-02-24	Searle & Co	Lactones of 17-carboxyalkylated estra-1, 3, 5(10)-triene-3, 17-diols and 3-ethers
US3547912A (en) *	1968-07-29	1970-12-15	American Home Prod	Derivatives of 2h-pyran-3(6h)-ones and preparation thereof
US3764596A (en) *	1971-06-22	1973-10-09	Sandoz Ag	17-dihydrofuranyl-substituted steroids
DE3306554A1 (de) *	1983-02-22	1984-08-23	Schering AG, 1000 Berlin und 4709 Bergkamen	Verfahren zur herstellung von 3-((delta)(pfeil hoch)4(pfeil hoch)-3-ketosteroid-17(alpha)-yl)-propionsaeurelactonen
DE3347510A1 (de) *	1983-12-27	1985-08-01	Schering AG, 1000 Berlin und 4709 Bergkamen	Verfahren zur herstellung von 3-oxo-17(alpha)-pregna-4,6-dien-21,17-carbolactonen
FR2596395B1 (fr) *	1986-03-26	1989-05-26	Roussel Uclaf	Nouveaux steroides comportant un cycle spirannique en position 17, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
ATE85342T1 (de) *	1987-12-12	1993-02-15	Akzo Nv	11-arylsteroid-derivate.
FR2688004A1 (fr) *	1992-02-27	1993-09-03	Roussel Uclaf	Nouveaux sterouides comportant en position 17 un radical methylene lactone, leur procede et des intermediaires de preparation, leur application comme medicaments.

1995
- 1995-10-18 IL IL11565995A patent/IL115659A/xx not_active IP Right Cessation
- 1995-10-19 TW TW084111021A patent/TW339337B/zh active
- 1995-10-23 CZ CZ19952755A patent/CZ287346B6/cs not_active IP Right Cessation
- 1995-10-23 ZA ZA958963A patent/ZA958963B/xx unknown
- 1995-10-24 ES ES95202865T patent/ES2157290T3/es not_active Expired - Lifetime
- 1995-10-24 US US08/547,176 patent/US5741786A/en not_active Expired - Fee Related
- 1995-10-24 DE DE69520022T patent/DE69520022T2/de not_active Expired - Fee Related
- 1995-10-24 DK DK95202865T patent/DK0709394T3/da active
- 1995-10-24 AT AT95202865T patent/ATE199015T1/de not_active IP Right Cessation
- 1995-10-24 PT PT95202865T patent/PT709394E/pt unknown
- 1995-10-24 EP EP95202865A patent/EP0709394B1/en not_active Expired - Lifetime
- 1995-10-25 NZ NZ280325A patent/NZ280325A/en unknown
- 1995-10-25 AU AU34457/95A patent/AU689642B2/en not_active Ceased
- 1995-10-26 PL PL95311135A patent/PL187083B1/pl not_active IP Right Cessation
- 1995-10-26 KR KR1019950038035A patent/KR100402636B1/ko not_active Expired - Fee Related
- 1995-10-26 RU RU95118123/04A patent/RU2168516C2/ru not_active IP Right Cessation
- 1995-10-26 FI FI955108A patent/FI113542B/fi not_active IP Right Cessation
- 1995-10-26 NO NO954293A patent/NO305252B1/no not_active IP Right Cessation
- 1995-10-26 BR BR9504576A patent/BR9504576A/pt not_active Application Discontinuation
- 1995-10-26 HU HU9503068A patent/HU221192B1/hu not_active IP Right Cessation
- 1995-10-26 CA CA002161490A patent/CA2161490A1/en not_active Abandoned
- 1995-10-27 TR TR95/01327A patent/TR199501327A2/xx unknown
- 1995-10-27 JP JP7280432A patent/JPH08225590A/ja active Pending
- 1995-10-27 CN CN95120353A patent/CN1052237C/zh not_active Expired - Fee Related
- 1995-10-28 SG SG1995001675A patent/SG33569A1/en unknown
2001
- 2001-04-06 GR GR20010400563T patent/GR3035713T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO954293L (no)	1996-04-29
PL187083B1 (pl)	2004-05-31
NZ280325A (en)	1997-03-24
EP0709394A3 (en)	1996-09-18
HU9503068D0 (en)	1995-12-28
EP0709394B1 (en)	2001-01-31
HUT73482A (en)	1996-08-28
US5741786A (en)	1998-04-21
CZ287346B6 (en)	2000-10-11
FI955108A0 (fi)	1995-10-26
PT709394E (pt)	2001-06-29
JPH08225590A (ja)	1996-09-03
ATE199015T1 (de)	2001-02-15
GR3035713T3 (en)	2001-07-31
RU2168516C2 (ru)	2001-06-10
DE69520022D1 (de)	2001-03-08
ES2157290T3 (es)	2001-08-16
IL115659A (en)	2000-06-01
EP0709394A2 (en)	1996-05-01
KR960014152A (ko)	1996-05-22
KR100402636B1 (ko)	2004-02-05
DE69520022T2 (de)	2001-06-13
CA2161490A1 (en)	1996-04-28
ZA958963B (en)	1996-05-23
TR199501327A3 (pt)	1996-06-21
AU689642B2 (en)	1998-04-02
PL311135A1 (en)	1996-04-29
NO305252B1 (no)	1999-04-26
FI113542B (fi)	2004-05-14
CN1131158A (zh)	1996-09-18
AU3445795A (en)	1996-05-09
DK0709394T3 (da)	2001-06-18
HU221192B1 (en)	2002-08-28
CZ275595A3 (en)	1996-05-15
FI955108L (fi)	1996-04-28
SG33569A1 (en)	1996-10-18
NO954293D0 (no)	1995-10-26
IL115659A0 (en)	1996-01-19
TR199501327A2 (tr)	1996-06-21
TW339337B (en)	1998-09-01
CN1052237C (zh)	2000-05-10

Legal Events

Date	Code	Title	Description
1997-11-18	FA	Application withdrawn
2018-03-27	B15K	Others concerning applications: alteration of classification	Ipc: C07J 21/00 (2006.01), C07J 1/00 (2006.0

Publication	Publication Date	Title
PL311135A1 (en)	1996-04-29	Steroids having a 17-spiromethylenlactone or lactole group, a method of manufacturing them, and pharmaceutical composition
MX9301032A (es)	1993-09-01	Compuestos farmaceuticos y procedimento para su preparacion
KR930004286A (ko)	1993-03-22	마일라르 반응 억제제
KR950018038A (ko)	1995-07-22	치환된 2β-모폴리노-안드로스탄 유도체
BR9502085A (pt)	1996-03-05	Derivado de 11,21-bis-fenil-19-norpregnano,processo de preparação do mesmo e composição farmaceutica
AU3009392A (en)	1993-06-24	17-spirofuran-3'-ylidene steroids
AU6476394A (en)	1994-12-22	19-nor steroids having a phenoxyalkylsulphonamide or phenoxyalkylsulphonylurea chain in position 11beta, preparation process and intermediates, use as medicaments and pharmaceutical compositions containing them
ES2003200A6 (es)	1988-10-16	Un procedimiento para la preparacion de esteroides aminoglicosidicos.
RU95118123A (ru)	1997-11-10	Стероиды с 17-спирометилен-лактоновой или -лактольной группой
YU49025B (sh)	2003-07-07	Novi derivati 17,20-epoksi pregnana, njihova primena u dobijanju kortizonskih derivata i intermedijera
IL112021A0 (en)	1995-03-15	Pharmaceutical compositions containing 1,2,3,4,4a,5,10,10a-octahydro-benzo-[g] quinoline derivatives for the prevention or delay of progressive atrophy of the optic nerve
CA2010982A1 (en)	1990-08-31	Osteogenesis promotion with use of vitamin d derivatives
DK0955286T3 (da)	2002-11-25	Dihydro- eller tetrahydronaphthalenderivater med (anti) østrogen virkning
FI873800A0 (fi)	1987-09-01	Nor-kolansyraderivat, foerfarande foer deras framstaellning, deras anvaendning samt farmaceutiska kompositioner innehaollande desamma.
TR200001405T2 (tr)	2001-05-21	11ß pozisyonunda ikameli/katkılı yeni 19-nor steroidler hazırlama metodu-ara maddeleri.
ATE42957T1 (de)	1989-05-15	Waessrige kristallsuspension von steroidglykoestern.
TH29335A (th)	1998-07-30	สเทียรอยด์ที่มีกลุ่ม 17-สไปโรเมธิลีน?แลคโทนหรือแลคทอล
IE861677L (en)	1987-01-24	11-methylene-15-ene steroids
ATE174597T1 (de)	1999-01-15	Tan-1251-verbindung, ihre derivate, herstellung und verwendung
EP0273357A3 (en)	1989-11-02	Fluorine-containing macrolide compounds, pharmaceutical compositions comprising the same and their use for the manufacture of medicaments