BR9508826A - Análogos de nucleosídeo antivirais contendo uma base de benzimidazol substituída ligada a um anel carboxílico - Google Patents
Análogos de nucleosídeo antivirais contendo uma base de benzimidazol substituída ligada a um anel carboxílicoInfo
- Publication number
- BR9508826A BR9508826A BR9508826A BR9508826A BR9508826A BR 9508826 A BR9508826 A BR 9508826A BR 9508826 A BR9508826 A BR 9508826A BR 9508826 A BR9508826 A BR 9508826A BR 9508826 A BR9508826 A BR 9508826A
- Authority
- BR
- Brazil
- Prior art keywords
- nucleoside analogs
- base attached
- substituted benzimidazole
- analogs containing
- antiviral nucleoside
- Prior art date
Links
- 230000000840 anti-viral effect Effects 0.000 title 1
- 125000003785 benzimidazolyl group Chemical class N1=C(NC2=C1C=CC=C2)* 0.000 title 1
- 239000002777 nucleoside Substances 0.000 title 1
- 150000003833 nucleoside derivatives Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/304,006 US5534535A (en) | 1992-03-09 | 1994-09-09 | Therapeutic nucleosides |
| PCT/US1995/011366 WO1996007646A1 (en) | 1994-09-09 | 1995-09-11 | Antiviral nucleoside analogues containing a substituted benzimidazole base attached to a carbocyclic ring |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9508826A true BR9508826A (pt) | 1997-09-30 |
Family
ID=23174626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9508826A BR9508826A (pt) | 1994-09-09 | 1995-09-11 | Análogos de nucleosídeo antivirais contendo uma base de benzimidazol substituída ligada a um anel carboxílico |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0779885A1 (cs) |
| JP (1) | JPH10505092A (cs) |
| CN (1) | CN1164855A (cs) |
| AP (1) | AP741A (cs) |
| AU (1) | AU3692895A (cs) |
| BR (1) | BR9508826A (cs) |
| CA (1) | CA2199502A1 (cs) |
| CZ (1) | CZ71297A3 (cs) |
| FI (1) | FI970959A7 (cs) |
| HU (1) | HUT77440A (cs) |
| IS (1) | IS4436A (cs) |
| NO (1) | NO971070L (cs) |
| NZ (1) | NZ294095A (cs) |
| OA (1) | OA10601A (cs) |
| PL (1) | PL319440A1 (cs) |
| SK (1) | SK29197A3 (cs) |
| WO (1) | WO1996007646A1 (cs) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5912356A (en) * | 1995-09-11 | 1999-06-15 | Glaxo Wellcome Inc. | Antiviral nucleoside analogues containing a substituted benzimidazole base attached to a carbocyclic ring |
| GB9600142D0 (en) * | 1996-01-05 | 1996-03-06 | Wellcome Found | Chemical compounds |
| US6413938B1 (en) | 1997-02-13 | 2002-07-02 | The Regents Of The University Of Michigan | Benzimidazole derivatives for the treatment of viral infections |
| AU744176B2 (en) | 1997-07-30 | 2002-02-14 | Glaxo Group Limited | Lyxofuranosyl benzimidazoles as antiviral agents |
| US6770666B2 (en) | 1999-12-27 | 2004-08-03 | Japan Tobacco Inc. | Fused-ring compounds and use thereof as drugs |
| CZ20013424A3 (cs) | 1999-12-27 | 2002-02-13 | Japan Tobacco Inc. | Sloučeniny s fúzovanými kruhy a jejich pouľití jako léčiva |
| GB0008939D0 (en) | 2000-04-11 | 2000-05-31 | Glaxo Group Ltd | Process for preparing substituted benzimidazole compounds |
| AR035543A1 (es) * | 2001-06-26 | 2004-06-16 | Japan Tobacco Inc | Agente terapeutico para la hepatitis c que comprende un compuesto de anillo condensado, compuesto de anillo condensado, composicion farmaceutica que lo comprende, compuestos de benzimidazol, tiazol y bifenilo utiles como intermediarios para producir dichos compuestos, uso del compuesto de anillo con |
| CN1834090B (zh) * | 2005-03-18 | 2011-06-29 | 中国科学院上海药物研究所 | 苯并咪唑类化合物、其制备方法以及用途 |
| EP2540727B1 (en) | 2007-08-02 | 2018-07-25 | Millennium Pharmaceuticals, Inc. | Sulfamoylating reagent |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9205071D0 (en) * | 1992-03-09 | 1992-04-22 | Wellcome Found | Therapeutic nucleosides |
-
1995
- 1995-09-11 JP JP8509679A patent/JPH10505092A/ja not_active Ceased
- 1995-09-11 HU HU9702310A patent/HUT77440A/hu unknown
- 1995-09-11 AU AU36928/95A patent/AU3692895A/en not_active Abandoned
- 1995-09-11 SK SK291-97A patent/SK29197A3/sk unknown
- 1995-09-11 AP APAP/P/1997/000940A patent/AP741A/en active
- 1995-09-11 CZ CZ97712A patent/CZ71297A3/cs unknown
- 1995-09-11 WO PCT/US1995/011366 patent/WO1996007646A1/en not_active Ceased
- 1995-09-11 CN CN95196148A patent/CN1164855A/zh active Pending
- 1995-09-11 PL PL95319440A patent/PL319440A1/xx unknown
- 1995-09-11 EP EP95934402A patent/EP0779885A1/en not_active Withdrawn
- 1995-09-11 NZ NZ294095A patent/NZ294095A/en unknown
- 1995-09-11 CA CA002199502A patent/CA2199502A1/en not_active Abandoned
- 1995-09-11 BR BR9508826A patent/BR9508826A/pt not_active Application Discontinuation
-
1997
- 1997-03-06 FI FI970959A patent/FI970959A7/fi unknown
- 1997-03-07 OA OA60973A patent/OA10601A/en unknown
- 1997-03-07 IS IS4436A patent/IS4436A/is unknown
- 1997-03-07 NO NO971070A patent/NO971070L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH10505092A (ja) | 1998-05-19 |
| SK29197A3 (en) | 1997-10-08 |
| PL319440A1 (en) | 1997-08-04 |
| MX9701789A (es) | 1997-10-31 |
| CZ71297A3 (en) | 1997-08-13 |
| AU3692895A (en) | 1996-03-27 |
| CN1164855A (zh) | 1997-11-12 |
| EP0779885A1 (en) | 1997-06-25 |
| FI970959A0 (fi) | 1997-03-06 |
| NO971070L (no) | 1997-05-07 |
| WO1996007646A1 (en) | 1996-03-14 |
| IS4436A (is) | 1997-03-07 |
| AP9700940A0 (en) | 1997-04-30 |
| HUT77440A (hu) | 1998-04-28 |
| CA2199502A1 (en) | 1996-03-14 |
| FI970959A7 (fi) | 1997-05-06 |
| NZ294095A (en) | 1998-08-26 |
| OA10601A (en) | 2002-09-03 |
| NO971070D0 (no) | 1997-03-07 |
| AP741A (en) | 1999-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB36 | Technical and formal requirements: requirement - article 36 of industrial property law | ||
| FA8 | Dismissal: dismissal - article 36, par. 1 of industrial property law |