BRPI0409955A - uso de antibióticos hìbridos de oxazolidinona - quinolina para o tratamento de antrax e outras infecções - Google Patents

uso de antibióticos hìbridos de oxazolidinona - quinolina para o tratamento de antrax e outras infecções

Info

Publication number
BRPI0409955A
BRPI0409955A BRPI0409955-9A BRPI0409955A BRPI0409955A BR PI0409955 A BRPI0409955 A BR PI0409955A BR PI0409955 A BRPI0409955 A BR PI0409955A BR PI0409955 A BRPI0409955 A BR PI0409955A
Authority
BR
Brazil
Prior art keywords
oxazolidinone
infections
hybrid
anthrax
treat anthrax
Prior art date
Application number
BRPI0409955-9A
Other languages
English (en)
Inventor
Christian Hubschwerlen
Jean-Luc Specklin
Daniel K Baeschlin
Hans Locher
Christine Schmitt
Original Assignee
Morphochem Ag Komb Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphochem Ag Komb Chemie filed Critical Morphochem Ag Komb Chemie
Publication of BRPI0409955A publication Critical patent/BRPI0409955A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

"USO DE ANTIBIóTICOS HìBRIDOS DE OXAZOLIDINONA - QUINOLINA PARA O TRATAMENTO DE ANTRAX E OUTRAS INFECçõES". A presente invenção refere-se ao uso de compostos, nos quais os farmacóforos de quinolona e oxazolidinona são ligados quimicamente através de um ligador que é estável sob condições fisiológicas, para o tratamento de antrax e outras infecções.
BRPI0409955-9A 2003-04-30 2004-04-06 uso de antibióticos hìbridos de oxazolidinona - quinolina para o tratamento de antrax e outras infecções BRPI0409955A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46694503P 2003-04-30 2003-04-30
US53082203P 2003-12-18 2003-12-18
PCT/EP2004/003650 WO2004096221A1 (en) 2003-04-30 2004-04-06 Use of oxazolidinone-quinoline hybrid antibiotics for the treatment of anthrax and other infections

Publications (1)

Publication Number Publication Date
BRPI0409955A true BRPI0409955A (pt) 2006-04-25

Family

ID=33423632

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0409955-9A BRPI0409955A (pt) 2003-04-30 2004-04-06 uso de antibióticos hìbridos de oxazolidinona - quinolina para o tratamento de antrax e outras infecções

Country Status (15)

Country Link
US (3) US20070155714A1 (pt)
EP (1) EP1620098B1 (pt)
JP (2) JP4805139B2 (pt)
KR (1) KR101101982B1 (pt)
AT (1) ATE397930T1 (pt)
AU (2) AU2004233557B2 (pt)
BR (1) BRPI0409955A (pt)
CA (1) CA2529347C (pt)
DE (1) DE602004014361D1 (pt)
ES (1) ES2308171T3 (pt)
IL (1) IL171546A (pt)
MX (1) MXPA05011654A (pt)
NZ (1) NZ543757A (pt)
RU (1) RU2351335C2 (pt)
WO (1) WO2004096221A1 (pt)

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KR101748891B1 (ko) 2009-03-11 2017-06-19 교린 세이야꾸 가부시키 가이샤 Ｇｓｋ-3 억제제로서의 7-시클로알킬아미노퀴놀론
JP5796412B2 (ja) 2011-08-26 2015-10-21 三菱電機株式会社 半導体素子の製造方法
JP6030146B2 (ja) * 2011-11-08 2016-11-24 アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ ２−オキソ−オキサゾリジン−３，５−ジイル抗生物質誘導体
CN105025929A (zh) 2013-03-08 2015-11-04 阿勒根公司 环孢菌素a-类固醇缀合物
US9402912B2 (en) 2013-03-08 2016-08-02 Allergan, Inc. Antibiotic conjugates directly linked with steroid drugs
CN105246476B (zh) * 2013-05-28 2019-11-15 莫弗凯姆联合化学股份公司 含噁唑烷酮-喹诺酮的联合疗法在治疗细菌感染中的应用
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DE10340485B4 (de) * 2003-09-03 2015-05-13 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden
CA2549675C (en) 2003-12-18 2012-11-20 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
AR054608A1 (es) 2005-08-08 2007-06-27 Actelion Pharmaceuticals Ltd Derivados de oxazolidinona enlazados a quinolonas como antibacterianos
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ATE544764T1 (de) 2006-11-10 2012-02-15 Actelion Pharmaceuticals Ltd 5-hydroxymethyloxazolidin-2-onderivate
CL2007003332A1 (es) 2006-11-24 2008-06-20 Actelion Pharmaceuticals Ltd Compuestos derivados de heterociclos condensados; compuestos intermediarios; composicion farmaceutica; y uso en la prevencion o tratamiento de infecciones bacterianas.
RU2527769C2 (ru) 2008-05-09 2014-09-10 Актелион Фармасьютиклз Лтд Производные 5-гидроксиметилоксазолидин-2-она для лечения бактериальных кишечных заболеваний

Also Published As

Publication number Publication date
JP4805139B2 (ja) 2011-11-02
US20070155714A1 (en) 2007-07-05
ATE397930T1 (de) 2008-07-15
WO2004096221A1 (en) 2004-11-11
JP5536706B2 (ja) 2014-07-02
DE602004014361D1 (de) 2008-07-24
MXPA05011654A (es) 2005-12-15
US8513231B2 (en) 2013-08-20
AU2010201659A1 (en) 2010-05-20
US20120135961A1 (en) 2012-05-31
RU2351335C2 (ru) 2009-04-10
US8268812B2 (en) 2012-09-18
JP2011184441A (ja) 2011-09-22
US20120322766A1 (en) 2012-12-20
NZ543757A (en) 2009-02-28
EP1620098A1 (en) 2006-02-01
HK1078806A1 (en) 2006-03-24
IL171546A (en) 2014-06-30
CA2529347C (en) 2011-09-06
CA2529347A1 (en) 2004-11-11
EP1620098B1 (en) 2008-06-11
KR101101982B1 (ko) 2012-01-02
KR20060025525A (ko) 2006-03-21
AU2004233557A1 (en) 2004-11-11
RU2005137032A (ru) 2007-06-10
AU2004233557B2 (en) 2010-02-18
ES2308171T3 (es) 2008-12-01
JP2006526577A (ja) 2006-11-24

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