BRPI0412202A - emplastro para imunização tendo um arranjo de microprojeções, e método - Google Patents

emplastro para imunização tendo um arranjo de microprojeções, e método

Info

Publication number
BRPI0412202A
BRPI0412202A BRPI0412202-0A BRPI0412202A BRPI0412202A BR PI0412202 A BRPI0412202 A BR PI0412202A BR PI0412202 A BRPI0412202 A BR PI0412202A BR PI0412202 A BRPI0412202 A BR PI0412202A
Authority
BR
Brazil
Prior art keywords
elements
microprojection
amount
immunization
distributing
Prior art date
Application number
BRPI0412202-0A
Other languages
English (en)
Inventor
Michel J N Cormier
James Matriano
Juanita A Johnson
Wendy A Young
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of BRPI0412202A publication Critical patent/BRPI0412202A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"EMPLASTRO PARA IMUNIZAçãO TENDO UM ARRANJO DE MICROPROJEçõES, E MéTODO". A presente invenção refere-se a elementos de microprojeções (10) que têm um reservatório que contém um agente antigênico, e métodos para usar tais elementos para vacinar mamíferos (como por exemplo, humanos). Os elementos de microprojeções são usados para distribuir por via transdérmica um agente antigênico (como por exemplo, um antígeno de vacina), com reações da pele substancialmente reduzidas. Isso é conseguido distribuindo uma quantidade indutora, e depois disso, distribuindo uma ou mais quantidades subseqüentes de reforço. A quantidade indutora é relativamente maior do que a quantidade de reforço. Esta tecnologia tem ampla aplicabilidade para uma ampla série de vacinas terapêuticas, para melhorar a eficácia e a conveniência do uso.
BRPI0412202-0A 2003-07-02 2004-07-01 emplastro para imunização tendo um arranjo de microprojeções, e método BRPI0412202A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48493003P 2003-07-02 2003-07-02
PCT/US2004/021393 WO2005002453A1 (en) 2003-07-02 2004-07-01 Microprojection array immunization patch and method

Publications (1)

Publication Number Publication Date
BRPI0412202A true BRPI0412202A (pt) 2006-08-22

Family

ID=33564036

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0412202-0A BRPI0412202A (pt) 2003-07-02 2004-07-01 emplastro para imunização tendo um arranjo de microprojeções, e método

Country Status (13)

Country Link
US (1) US20050025778A1 (pt)
EP (1) EP1643918A1 (pt)
JP (1) JP2007521092A (pt)
KR (1) KR20060037320A (pt)
CN (1) CN1845708A (pt)
AR (1) AR044985A1 (pt)
AU (1) AU2004253571A1 (pt)
BR (1) BRPI0412202A (pt)
CA (1) CA2530954A1 (pt)
PE (1) PE20050288A1 (pt)
TW (1) TW200513280A (pt)
UY (1) UY28398A1 (pt)
WO (1) WO2005002453A1 (pt)

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Also Published As

Publication number Publication date
AR044985A1 (es) 2005-10-12
EP1643918A1 (en) 2006-04-12
CN1845708A (zh) 2006-10-11
KR20060037320A (ko) 2006-05-03
PE20050288A1 (es) 2005-04-29
AU2004253571A1 (en) 2005-01-13
UY28398A1 (es) 2004-11-08
CA2530954A1 (en) 2005-01-13
WO2005002453A1 (en) 2005-01-13
US20050025778A1 (en) 2005-02-03
TW200513280A (en) 2005-04-16
JP2007521092A (ja) 2007-08-02

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