BRPI0509475A - matrizes de hidrogel aniÈnico com liberação modificada dependente do ph como veìculos de fármacos - Google Patents

matrizes de hidrogel aniÈnico com liberação modificada dependente do ph como veìculos de fármacos

Info

Publication number
BRPI0509475A
BRPI0509475A BRPI0509475-5A BRPI0509475A BRPI0509475A BR PI0509475 A BRPI0509475 A BR PI0509475A BR PI0509475 A BRPI0509475 A BR PI0509475A BR PI0509475 A BRPI0509475 A BR PI0509475A
Authority
BR
Brazil
Prior art keywords
modified release
drug carriers
hydrogel matrices
anionic hydrogel
dependent modified
Prior art date
Application number
BRPI0509475-5A
Other languages
English (en)
Inventor
Gaetano Giammona
Delia Mandracchia
Original Assignee
Sigma Tau Ind Famaceutiche Riu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Famaceutiche Riu filed Critical Sigma Tau Ind Famaceutiche Riu
Publication of BRPI0509475A publication Critical patent/BRPI0509475A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

MATRIZES DE HIDROGEL ANIÈNICO COM LIBERAçãO MODIFICADA DEPENDENTE DO PH COMO VEìCULOS DE FáRMACOS. A presente invenção refere-se a composições com liberação modificada dependente do pH que são descritas, consistindo em matrizes de hidrogel contendo um ou mais ingredientes ativos, nas quais as matrizes referidas são adequadas para liberar os ingredientes ativos referidos em uma maneira prolongada em dados sítios do como.
BRPI0509475-5A 2004-04-01 2005-02-16 matrizes de hidrogel aniÈnico com liberação modificada dependente do ph como veìculos de fármacos BRPI0509475A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000168A ITRM20040168A1 (it) 2004-04-01 2004-04-01 Composizione a rilascio modificato ph dipendente.
PCT/IT2005/000081 WO2005094792A1 (en) 2004-04-01 2005-02-16 Anionic hydrogel matrices with ph dependent modified release as drug carriers

Publications (1)

Publication Number Publication Date
BRPI0509475A true BRPI0509475A (pt) 2007-09-11

Family

ID=34961555

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0509475-5A BRPI0509475A (pt) 2004-04-01 2005-02-16 matrizes de hidrogel aniÈnico com liberação modificada dependente do ph como veìculos de fármacos

Country Status (20)

Country Link
US (1) US20070166383A1 (pt)
EP (1) EP1729732B1 (pt)
JP (1) JP2007530666A (pt)
KR (1) KR20060133578A (pt)
CN (1) CN1913875B (pt)
AT (1) ATE428405T1 (pt)
AU (1) AU2005228716B2 (pt)
BR (1) BRPI0509475A (pt)
CA (1) CA2551797A1 (pt)
CY (1) CY1109209T1 (pt)
DE (1) DE602005013935D1 (pt)
DK (1) DK1729732T3 (pt)
ES (1) ES2325626T3 (pt)
HR (1) HRP20090329T1 (pt)
IT (1) ITRM20040168A1 (pt)
PL (1) PL1729732T3 (pt)
PT (1) PT1729732E (pt)
RS (1) RS51178B (pt)
SI (1) SI1729732T1 (pt)
WO (1) WO2005094792A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4746883B2 (ja) * 2005-01-28 2011-08-10 リンテック株式会社 ハイドロゲル基剤、パップ剤基剤、パップ剤及び水性ゲルシート
EP2379226B1 (en) 2008-12-31 2016-04-20 3M Innovative Properties Company Live bioload detection using microparticles
EP2379697A2 (en) 2008-12-31 2011-10-26 3M Innovative Properties Company Sampling devices and methods for concentrating microorganisms
US8845801B2 (en) 2009-12-30 2014-09-30 Regents Of The University Of Minnesota Bone cement and method
EP2519355B1 (en) 2009-12-30 2017-01-25 3M Innovative Properties Company Live bioload detection using microparticles
WO2011090349A2 (ko) * 2010-01-21 2011-07-28 광주과학기술원 피부투과도, 세포유입 및 종양전달성이 증가된 나노운반체
KR101228106B1 (ko) * 2010-01-21 2013-02-01 광주과학기술원 피부투과도, 세포유입 및 종양전달성이 증가된 나노운반체
CN103330702B (zh) * 2013-07-02 2016-03-02 江苏长泰药业有限公司 含有拟交感神经胺盐和诱导凝胶体系的医药组合物
CN108452291A (zh) * 2018-07-04 2018-08-28 西南大学 用天然丝胶蛋白治疗溃疡性结肠炎的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4071508A (en) * 1975-02-11 1978-01-31 Plastomedical Sciences, Inc. Anionic hydrogels based on hydroxyalkyl acrylates and methacrylates
IT1284661B1 (it) * 1996-06-06 1998-05-21 Sigma Tau Ind Farmaceuti Uso di alcanoil l-carnitine nel trattamento terapeutico di malattie infiammatorie croniche intestinali.
DE19653631A1 (de) * 1996-12-20 1998-06-25 Basf Coatings Ag Verfahren zum Herstellen von durch Strahlung vernetzbaren polymeren Acryl- oder Methacrylsäureestern
US6458386B1 (en) * 1997-06-03 2002-10-01 Innogenetics N.V. Medicaments based on polymers composed of methacrylamide-modified gelatin
KR100845769B1 (ko) * 1999-02-03 2008-07-11 파우더젝트 리서치 리미티드 하이드로겔 입자 제제
US6547182B2 (en) * 2001-07-19 2003-04-15 Aerojet-General Corporation Solid rocket motor bolted thrust takeout structure
US7204997B2 (en) * 2002-01-29 2007-04-17 Supratek Pharma Inc. Responsive microgel and methods related thereto

Also Published As

Publication number Publication date
CN1913875B (zh) 2011-08-31
AU2005228716B2 (en) 2010-07-15
WO2005094792A1 (en) 2005-10-13
EP1729732A1 (en) 2006-12-13
DK1729732T3 (da) 2009-08-10
AU2005228716A1 (en) 2005-10-13
CN1913875A (zh) 2007-02-14
SI1729732T1 (sl) 2009-08-31
HRP20090329T1 (hr) 2009-09-30
CA2551797A1 (en) 2005-10-13
ATE428405T1 (de) 2009-05-15
EP1729732B1 (en) 2009-04-15
PT1729732E (pt) 2009-07-02
ES2325626T3 (es) 2009-09-10
KR20060133578A (ko) 2006-12-26
PL1729732T3 (pl) 2009-09-30
JP2007530666A (ja) 2007-11-01
CY1109209T1 (el) 2014-07-02
RS51178B (sr) 2010-10-31
ITRM20040168A1 (it) 2004-07-01
DE602005013935D1 (de) 2009-05-28
US20070166383A1 (en) 2007-07-19

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2204 DE 02/04/2013.