BRPI0511036A - formulações de solução farmacêuticas contendo 17-aag - Google Patents

formulações de solução farmacêuticas contendo 17-aag

Info

Publication number
BRPI0511036A
BRPI0511036A BRPI0511036-0A BRPI0511036A BRPI0511036A BR PI0511036 A BRPI0511036 A BR PI0511036A BR PI0511036 A BRPI0511036 A BR PI0511036A BR PI0511036 A BRPI0511036 A BR PI0511036A
Authority
BR
Brazil
Prior art keywords
aag
amount
pharmaceutical solution
volume
solution formulations
Prior art date
Application number
BRPI0511036-0A
Other languages
English (en)
Inventor
Ziyang Zhong
Peter J Licari
Original Assignee
Kosan Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kosan Biosciences Inc filed Critical Kosan Biosciences Inc
Publication of BRPI0511036A publication Critical patent/BRPI0511036A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

FORMULAçõES DE SOLUçãO FARMACêUTICAS CONTENDO 17-AAG. A presente invenção refere-se a uma formulação de solução farmacêutica contendo 17-AAG em uma quantidade de até 15 mg/ml dissolvidos em um veículo incluindo (i) um primeiro componente que é etanol, em uma quantidade de entre cerca de 40 e cerca de 60% em volume; (ii) um segundo componente que é óleo de castor polietoxilado, em uma quantidade cerca de 15 a cerca de 50% em volume; e (iii) um terceiro composto que é selecionado do grupo consistindo em propileno glicol, PEG 300, PEG 400, glicerol, e combinações destes, em uma quantidade de entre cerca de 0 a cerca de 35% em volume.
BRPI0511036-0A 2004-05-11 2005-05-06 formulações de solução farmacêuticas contendo 17-aag BRPI0511036A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57021504P 2004-05-11 2004-05-11
US11/123,570 US20050256097A1 (en) 2004-05-11 2005-05-05 Pharmaceutical solution formulations containing 17-AAG
PCT/US2005/016010 WO2005110398A2 (en) 2004-05-11 2005-05-06 Pharmaceutical solution formulations containing 17-aag

Publications (1)

Publication Number Publication Date
BRPI0511036A true BRPI0511036A (pt) 2007-11-27

Family

ID=35310196

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0511036-0A BRPI0511036A (pt) 2004-05-11 2005-05-06 formulações de solução farmacêuticas contendo 17-aag

Country Status (10)

Country Link
US (1) US20050256097A1 (pt)
EP (1) EP1744743A2 (pt)
JP (1) JP2007537258A (pt)
AU (1) AU2005244115A1 (pt)
BR (1) BRPI0511036A (pt)
CA (1) CA2565583A1 (pt)
IL (1) IL178689A0 (pt)
MX (1) MXPA06012935A (pt)
RU (1) RU2382643C2 (pt)
WO (1) WO2005110398A2 (pt)

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JP2008539265A (ja) * 2005-04-29 2008-11-13 コーザン バイオサイエンシス インコーポレイテッド １７−ａａｇ又は１７−ａｇ又はどちらかのプロドラッグを使用する多発性骨髄腫の治療方法
JP2008539273A (ja) * 2005-04-29 2008-11-13 コーザン バイオサイエンシス インコーポレイテッド １７−ａａｇ又は１７−ａｇ又はどちらかのプロドラッグをプロテアソーム阻害剤と組み合わせて使用する多発性骨髄腫の治療方法
US7648976B2 (en) * 2005-11-23 2010-01-19 Bristol-Myers Squibb Company 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations
US20090042847A1 (en) * 2005-11-23 2009-02-12 Kosan Biosciences Incorporated 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations
US20070167422A1 (en) * 2006-01-18 2007-07-19 Yu Kwok S Pharmaceutical compositions comprising 17-allylamino-17-demethoxygeldanamycin
WO2008044045A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
WO2008044041A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
WO2008055386A1 (fr) * 2006-11-10 2008-05-15 Shenzhen Shengeryimei Biotech Co., Ltd. Composition pharmaceutique hydrosoluble pour injection de 17-allyl amino-17-déméthoxy geldanamycine (17-aag)
PE20081506A1 (es) * 2006-12-12 2008-12-09 Infinity Discovery Inc Formulaciones de ansamicina
CN101688227B (zh) 2007-01-26 2013-07-24 科森生物科学公司 通过工程化生物合成制备的大环内酰胺
EP2180880A2 (en) * 2007-07-09 2010-05-05 Glen S. Kwon Micelle encapsulation of therapeutic agents
BRPI0819081A8 (pt) * 2007-10-08 2016-08-30 Fovea Pharmaceuticals Sa Formulação oftálmica aquosa, processo para preparar a mesma, e, método para inibir, tratar ou prevenir doenças oculares e doença ou condição relacionada, em um paciente em necessidade de tal tratamento
US20090258869A1 (en) * 2008-02-08 2009-10-15 The Regents Of The University Of California Methods and compounds for treatment or prevention of substance-related disorders
ES3058497T3 (en) 2008-09-17 2026-03-11 Amryt Endo Inc Pharmaceutical compositions comprising polypeptides and related methods of delivery
WO2011038278A2 (en) 2009-09-25 2011-03-31 Wisconsin Alumni Research Foundation Micelle encapsulation of therapeutic agents
EP2547333B1 (en) * 2010-03-18 2017-08-23 Innopharma, Inc. Stable bortezomib formulations
US8945627B2 (en) 2011-05-05 2015-02-03 Wisconsin Alumni Research Foundation Micelles for the solubilization of gossypol
US10682415B2 (en) 2013-07-22 2020-06-16 Wisconsin Alumni Research Foundation Thermogel formulation for combination drug delivery
EP3230322B1 (en) 2014-12-11 2020-10-07 University of Utah Research Foundation Bi-functional allosteric protein-drug molecules for targeted therapy
PL3253401T3 (pl) 2015-02-03 2025-08-04 Amryt Endo, Inc. Leczenie akromegalii oktreotydem doustnym
JP2018008922A (ja) * 2015-08-04 2018-01-18 わかもと製薬株式会社 ステロイド白内障の予防及び治療
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods

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Also Published As

Publication number Publication date
EP1744743A2 (en) 2007-01-24
RU2382643C2 (ru) 2010-02-27
US20050256097A1 (en) 2005-11-17
JP2007537258A (ja) 2007-12-20
IL178689A0 (en) 2007-02-11
RU2006143666A (ru) 2008-06-20
WO2005110398A2 (en) 2005-11-24
MXPA06012935A (es) 2007-01-26
WO2005110398A3 (en) 2006-05-04
AU2005244115A1 (en) 2005-11-24
CA2565583A1 (en) 2005-11-24

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A E 8A ANUIDADE

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2204 DE 02/04/2013.