BRPI0511173A - 1-fenil-1,5-diidro-pirido-(3,2b)indol-2-onas substituìdas nas posições 6,7,8,9, de utilidade como agentes farmacêuticos antiinfecciosos - Google Patents

1-fenil-1,5-diidro-pirido-(3,2b)indol-2-onas substituìdas nas posições 6,7,8,9, de utilidade como agentes farmacêuticos antiinfecciosos

Info

Publication number
BRPI0511173A
BRPI0511173A BRPI0511173-0A BRPI0511173A BRPI0511173A BR PI0511173 A BRPI0511173 A BR PI0511173A BR PI0511173 A BRPI0511173 A BR PI0511173A BR PI0511173 A BRPI0511173 A BR PI0511173A
Authority
BR
Brazil
Prior art keywords
substituted
methanimidamidyl
indol
pharmaceutical agents
het
Prior art date
Application number
BRPI0511173-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Bart Rudolf Romanie Kesteleyn
Sandrine Marie Hele Vendeville
Natalie Maria Franc Kindermans
Dominique Louis Nest Surleraux
Pierre Jean-Marie Be Raboisson
Piet Tom Bert Paul Wigerinck
Annick Ann Peeters
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of BRPI0511173A publication Critical patent/BRPI0511173A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BRPI0511173-0A 2004-05-17 2005-05-17 1-fenil-1,5-diidro-pirido-(3,2b)indol-2-onas substituìdas nas posições 6,7,8,9, de utilidade como agentes farmacêuticos antiinfecciosos BRPI0511173A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04102170 2004-05-17
PCT/EP2005/052263 WO2005111035A1 (en) 2004-05-17 2005-05-17 6,7,8,9-substituted 1-phenyl-1,5-dihydro-pyrido[3,2-b]indol-2-ones useful as anti-infective pharmaceutical agents

Publications (1)

Publication Number Publication Date
BRPI0511173A true BRPI0511173A (pt) 2007-12-04

Family

ID=34929105

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0511173-0A BRPI0511173A (pt) 2004-05-17 2005-05-17 1-fenil-1,5-diidro-pirido-(3,2b)indol-2-onas substituìdas nas posições 6,7,8,9, de utilidade como agentes farmacêuticos antiinfecciosos

Country Status (14)

Country Link
US (2) US7622581B2 (de)
EP (1) EP1751156B1 (de)
JP (1) JP2007538050A (de)
CN (1) CN1976930B (de)
AR (1) AR049637A1 (de)
AT (1) ATE481403T1 (de)
BR (1) BRPI0511173A (de)
DE (1) DE602005023600D1 (de)
ES (1) ES2351702T3 (de)
MX (1) MXPA06013313A (de)
PL (1) PL1751156T3 (de)
RU (1) RU2377243C2 (de)
TW (1) TW200607502A (de)
WO (1) WO2005111035A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7994187B2 (en) 2006-04-03 2011-08-09 Tibotec Pharmaceuticals Ltd. HIV inhibiting 3,4-dihydro-imidazo[4,5-B]pyridin-5-ones
WO2008037783A1 (en) * 2006-09-29 2008-04-03 Tibotec Pharmaceuticals Ltd. Process for preparing 2-oxo-2,5-dihydro-1h-pyrido[3,2-b]indole-3-carbonitriles
BRPI1014821A2 (pt) 2009-04-09 2016-04-05 Boehringer Ingelheim Int "inibidores de replicação de hiv"
SG185400A1 (en) * 2010-05-14 2012-12-28 Affectis Pharmaceuticals Ag Novel methods for the preparation of p2x7r antagonists
RU2451680C1 (ru) 2011-02-21 2012-05-27 Общество С Ограниченной Ответственностью "Научно-Исследовательская Компания "Медбиофарм" Клатратный комплекс циклодекстрина или арабиногалактана с 9-фенил-симм-октагидроселеноксантеном, способ его получения (варианты), фармацевтическая композиция и лекарственное средство
RU2464042C1 (ru) * 2011-03-31 2012-10-20 Общество С Ограниченной Ответственностью "Научно-Исследовательская Компания "Медбиофарм" КЛАТРАТНЫЙ КОМПЛЕКС β-ЦИКЛОДЕКСТРИНА С ПРОИЗВОДНЫМ 5-ГИДРОКСИ-4-АМИНОМЕТИЛ-1-ЦИКЛОГЕКСИЛ(ИЛИ ЦИКЛОГЕПТИЛ)-3-АЛКОКСИКАРБОНИЛИНДОЛА, СПОСОБ ЕГО ПОЛУЧЕНИЯ (ВАРИАНТЫ), ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ И ЛЕКАРСТВЕННОЕ СРЕДСТВО
CA2848229C (en) 2011-09-16 2019-08-27 Fovea Pharmaceuticals Aniline derivatives, their preparation and their therapeutic application
RU2640081C1 (ru) * 2016-07-11 2017-12-26 Общество с ограниченной ответственностью "ЛАЙФ САЙНСЕС ОХФК" Фармацевтическая композиция и лекарственное средство на основе клатратного комплекса N-карбамоилметил-4-фенил-2-пирролидон или 4-фенилпирацетам с циклодекстрином, способы его получения (варианты)
JP7374916B2 (ja) * 2018-03-20 2023-11-07 コンパニー ゼネラール デ エタブリッスマン ミシュラン 少なくとも３重撚りを有する改善されたアラミド繊維コード
CN108530381B (zh) * 2018-05-07 2021-09-21 上海科技大学 一种由酰胺酯制备二胺衍生物的方法
US20240208984A1 (en) * 2021-03-31 2024-06-27 Virginia Commonwealth University Bivalent ligands to understand dimerization of the mu opioid receptor and the chemokine receptor ccr5 in neurological disorders

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB427857A (en) 1934-08-02 1935-05-01 Newsum Sons & Company Ltd H A new or improved system of construction for skeleton structures, particularly vehicle body frames and door frames
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
PH30929A (en) 1992-09-03 1997-12-23 Janssen Pharmaceutica Nv Beads having a core coated with an antifungal and a polymer.
PT721331E (pt) 1993-10-01 2002-05-31 Astrazeneca Ab Processo i
RU2140417C1 (ru) * 1995-10-17 1999-10-27 Институт физиологически активных веществ РАН Производные гидрированных пиридо(4,3-b)индолов, способы их получения, фармацевтическая композиция и способ лечения
WO1997044014A1 (en) 1996-05-20 1997-11-27 Janssen Pharmaceutica N.V. Antifungal compositions with improved bioavailability
SK284813B6 (sk) 1997-03-26 2005-12-01 Janssen Pharmaceutica N. V. Peleta obsahujúca itrakonazol, spôsob jej prípravy a farmaceutická dávková forma s jej obsahom
AU2002246658A1 (en) 2000-12-18 2002-07-24 Makarov, Vadim Benzoylalkylindolepyridinium compounds and pharmaceutical compositions comprising such compounds
WO2002059123A2 (en) * 2000-12-18 2002-08-01 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Benzoylalkylindolepyridinium compounds and pharmaceutical compositions comprising such compounds
JP2005508968A (ja) * 2001-10-19 2005-04-07 トランス　テック　ファーマ，インコーポレイテッド ＰＴＰ阻害剤としてのβ−カルボリン誘導体
EA009871B1 (ru) * 2002-11-15 2008-04-28 Тиботек Фармасьютикалз Лтд. Замещённые индолпиридиниевые соединения в качестве противоинфекционного средства

Also Published As

Publication number Publication date
CN1976930A (zh) 2007-06-06
MXPA06013313A (es) 2007-02-02
ATE481403T1 (de) 2010-10-15
US20070167434A1 (en) 2007-07-19
DE602005023600D1 (de) 2010-10-28
AR049637A1 (es) 2006-08-23
US7622581B2 (en) 2009-11-24
ES2351702T3 (es) 2011-02-09
EP1751156A1 (de) 2007-02-14
WO2005111035A1 (en) 2005-11-24
CN1976930B (zh) 2011-01-19
JP2007538050A (ja) 2007-12-27
TW200607502A (en) 2006-03-01
RU2006144852A (ru) 2008-06-27
PL1751156T3 (pl) 2011-03-31
EP1751156B1 (de) 2010-09-15
US20100029635A1 (en) 2010-02-04
RU2377243C2 (ru) 2009-12-27

Similar Documents

Publication Publication Date Title
BRPI0511173A (pt) 1-fenil-1,5-diidro-pirido-(3,2b)indol-2-onas substituìdas nas posições 6,7,8,9, de utilidade como agentes farmacêuticos antiinfecciosos
AR052887A1 (es) Derivados de tiazol, composiciones farmaceuticas que los contienen y su uso en la fabricacion de un medicamento para tratar enfermedades mediadas por la inhibicion de la protein quinasa
BR112012003955A2 (pt) compostos heterocíclicos tricíclicos como inibidores da fosfoinositídeos 3-quinase
BRPI0709633B8 (pt) derivados de piridina e pirimidina como antagonistas de mglur2, composição farmacêutica e uso dos mesmos
SI2091948T1 (sl) Novi inhibitorji glutaminil ciklaze
ECSP099394A (es) Derivados de quinuclidinol como antogonistas de receptores muscarínicos
CR10383A (es) Derivados triazolopirazina.
MX381849B (es) Compuestos a base de pirazol[1,5-a]pirimidina, composiciones que los comprenden, y métodos para su uso.
CR10915A (es) Compuestos y metodos de uso de inhibidor phosphoinositide 3-kinase
AR064197A1 (es) Derivados de pirimidina y piridina inhibidores de la proteina quinasa
CL2010001348A1 (es) Compuestos derivados de 1-oxo-2,3-dihidro-1h-isoindolin-5-il)-isoxazol-3-carboxamida, potenciadores de los mglur2; composicion farmaceutica; y su uso para aliviar los sintomas o disminuir la aparicion de los sintomas de ezquizofrenia o ansiedad.
GT200500240A (es) Nuevos herbicidas
NI200900032A (es) Compuestos de pirido (2, 3-d) pirimidinonay su uso como inhibidores de pi3
PE20151651A1 (es) Derivado de tetrahidroimidazol[1,5-d][1,4]oxazepina
BRPI0511621A (pt) compostos orgánicos
ECSP099750A (es) Imidazoquinolinas con propiedades inmunomoduladoras
CR11491A (es) Derivados de tiazol usados como inhibidores de pi 3-cinasa
MX2019001093A (es) Profarmacos de metilfenidato, procesos de elaboracion y uso de los mismos.
BR112013032391A2 (pt) antagonistas de trpv4
BRPI0718966B8 (pt) composto, composição farmacêutica, inibidor plk1 e agente antitumoral
BRPI0806264A2 (pt) derivados ciclizados como inibidores de eg-5
CR10376A (es) Derivados de terfenil para el tratamiento de la enfermedad de alzheimer
AR063139A1 (es) Inhibidores de metaloproteasas derivados de heterociclos. composiciones farmaceuticas.
BR112014031616A2 (pt) compostos de fenoxietil piperidina
AR061806A1 (es) Derivados de alquilpiridazina como inhibidores de 11b-hsd1 (t2d)

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2204 DE 02/04/2013.