BRPI0512420A - novos derivados de piperidina como moduladores do receptor de quimocina ccr5 - Google Patents
novos derivados de piperidina como moduladores do receptor de quimocina ccr5Info
- Publication number
- BRPI0512420A BRPI0512420A BRPI0512420-4A BRPI0512420A BRPI0512420A BR PI0512420 A BRPI0512420 A BR PI0512420A BR PI0512420 A BRPI0512420 A BR PI0512420A BR PI0512420 A BRPI0512420 A BR PI0512420A
- Authority
- BR
- Brazil
- Prior art keywords
- chemokine receptor
- receptor modulators
- piperidine derivatives
- ccr5 chemokine
- new piperidine
- Prior art date
Links
- 102000009410 Chemokine receptor Human genes 0.000 title 1
- 108050000299 Chemokine receptor Proteins 0.000 title 1
- 150000003053 piperidines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000004274 CCR5 Receptors Human genes 0.000 abstract 1
- 108010017088 CCR5 Receptors Proteins 0.000 abstract 1
- 238000013160 medical therapy Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0401657A SE0401657D0 (sv) | 2004-06-24 | 2004-06-24 | Chemical compounds |
| PCT/SE2005/000952 WO2006001751A1 (en) | 2004-06-24 | 2005-06-20 | Chemical compounds i |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0512420A true BRPI0512420A (pt) | 2008-03-04 |
Family
ID=32733687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0512420-4A BRPI0512420A (pt) | 2004-06-24 | 2005-06-20 | novos derivados de piperidina como moduladores do receptor de quimocina ccr5 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20070259914A1 (es) |
| EP (1) | EP1761494B1 (es) |
| JP (1) | JP5147393B2 (es) |
| CN (1) | CN101006058A (es) |
| AR (1) | AR049830A1 (es) |
| AT (1) | ATE465148T1 (es) |
| AU (1) | AU2005257707B2 (es) |
| BR (1) | BRPI0512420A (es) |
| CA (1) | CA2571087A1 (es) |
| DE (1) | DE602005020787D1 (es) |
| ES (1) | ES2342181T3 (es) |
| IL (1) | IL179729A0 (es) |
| MX (1) | MXPA06014413A (es) |
| MY (1) | MY139268A (es) |
| NO (1) | NO20070431L (es) |
| RU (1) | RU2381216C2 (es) |
| SE (1) | SE0401657D0 (es) |
| TW (1) | TW200610759A (es) |
| UA (1) | UA88303C2 (es) |
| UY (1) | UY28974A1 (es) |
| WO (1) | WO2006001751A1 (es) |
| ZA (1) | ZA200610526B (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200610761A (en) * | 2004-04-23 | 2006-04-01 | Astrazeneca Ab | Chemical compounds |
| EP2066674B1 (en) | 2006-09-18 | 2010-06-30 | F.Hoffmann-La Roche Ag | Octahydropyrrolo [3, 4-c] pyrrole derivatives and their use as antiviral agents |
| EP2173715A2 (en) * | 2007-07-13 | 2010-04-14 | Euroscreen S.A. | Use of piperidine derivatives as agonists of chemokine receptor activity |
| WO2009151910A2 (en) * | 2008-05-25 | 2009-12-17 | Wyeth | Combination product of receptor tyrosine kinase inhibitor and fatty acid synthase inhibitor for treating cancer |
| WO2012113103A1 (en) | 2011-02-25 | 2012-08-30 | Helsinn Healthcare S.A. | Asymmetric ureas and medical uses thereof |
| GB201321746D0 (en) * | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic agents |
| NO2699580T3 (es) | 2014-01-24 | 2018-02-24 | ||
| CA3017048C (en) | 2016-03-22 | 2023-11-07 | Helsinn Healthcare Sa | Benzenesulfonyl-asymmetric ureas and medical uses thereof |
| US20220072013A1 (en) * | 2018-12-21 | 2022-03-10 | Ca*Tx, Inc. | Pharmaceutical Combinations for the Treatment of Cancer |
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| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| WO1997030035A1 (en) | 1996-02-13 | 1997-08-21 | Zeneca Limited | Quinazoline derivatives as vegf inhibitors |
| ES2169355T3 (es) | 1996-03-05 | 2002-07-01 | Astrazeneca Ab | Derivados de 4-anilinoquinazolina. |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| PL192083B1 (pl) * | 1997-11-18 | 2006-08-31 | Dupont Pharmaceuticals Res Lab | Pochodne amin cyklicznych i ich zastosowanie |
| EP1013276A1 (en) * | 1998-12-23 | 2000-06-28 | Pfizer Inc. | Aminoazacycloalkanes as CCR5 modulators |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| SE9902987D0 (sv) * | 1999-08-24 | 1999-08-24 | Astra Pharma Prod | Novel compounds |
| IL152682A0 (en) | 2000-05-31 | 2003-06-24 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| HUP0301742A3 (en) | 2000-07-07 | 2005-08-29 | Angiogene Pharm Ltd | Colchinol derivatives as angiogenesis inhibitors, process for producing them, pharmaceutical compositions containing them and their use |
| BR0112224A (pt) | 2000-07-07 | 2003-06-10 | Angiogene Pharm Ltd | Composto, composição farmacêutica, uso de um composto ou de um sal, solvato ou pró-droga farmaceuticamente aceitável do mesmo, e, processo para preparar um composto |
| SE0103818D0 (sv) * | 2001-11-15 | 2001-11-15 | Astrazeneca Ab | Chemical compounds |
| SE0103819D0 (sv) * | 2001-11-15 | 2001-11-15 | Astrazeneca Ab | Chemical compounds |
| RU2005118407A (ru) * | 2002-12-13 | 2006-03-10 | СмитКлайн Бичем Корпорейшн (US) | Производные пиперидина в качестве антагонистов ccr5 |
| AR042628A1 (es) * | 2002-12-20 | 2005-06-29 | Astrazeneca Ab | Derivados de piperidina como moduladores del receptor ccr5 |
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2004
- 2004-06-24 SE SE0401657A patent/SE0401657D0/xx unknown
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2005
- 2005-06-13 TW TW094119533A patent/TW200610759A/zh unknown
- 2005-06-20 AU AU2005257707A patent/AU2005257707B2/en not_active Ceased
- 2005-06-20 JP JP2007518001A patent/JP5147393B2/ja not_active Expired - Fee Related
- 2005-06-20 RU RU2006146877/04A patent/RU2381216C2/ru not_active IP Right Cessation
- 2005-06-20 DE DE602005020787T patent/DE602005020787D1/de not_active Expired - Lifetime
- 2005-06-20 MX MXPA06014413A patent/MXPA06014413A/es not_active Application Discontinuation
- 2005-06-20 US US11/628,724 patent/US20070259914A1/en not_active Abandoned
- 2005-06-20 AT AT05753676T patent/ATE465148T1/de not_active IP Right Cessation
- 2005-06-20 CA CA002571087A patent/CA2571087A1/en not_active Abandoned
- 2005-06-20 EP EP05753676A patent/EP1761494B1/en not_active Expired - Lifetime
- 2005-06-20 CN CNA2005800284341A patent/CN101006058A/zh active Pending
- 2005-06-20 BR BRPI0512420-4A patent/BRPI0512420A/pt not_active IP Right Cessation
- 2005-06-20 ES ES05753676T patent/ES2342181T3/es not_active Expired - Lifetime
- 2005-06-20 UA UAA200613008A patent/UA88303C2/ru unknown
- 2005-06-20 WO PCT/SE2005/000952 patent/WO2006001751A1/en not_active Ceased
- 2005-06-21 UY UY28974A patent/UY28974A1/es unknown
- 2005-06-22 AR ARP050102573A patent/AR049830A1/es unknown
- 2005-06-22 MY MYPI20052861A patent/MY139268A/en unknown
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2006
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- 2006-12-14 ZA ZA200610526A patent/ZA200610526B/xx unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| MY139268A (en) | 2009-09-30 |
| ATE465148T1 (de) | 2010-05-15 |
| UA88303C2 (ru) | 2009-10-12 |
| CA2571087A1 (en) | 2006-01-05 |
| AU2005257707A1 (en) | 2006-01-05 |
| DE602005020787D1 (de) | 2010-06-02 |
| WO2006001751A1 (en) | 2006-01-05 |
| US20070259914A1 (en) | 2007-11-08 |
| MXPA06014413A (es) | 2007-02-19 |
| JP5147393B2 (ja) | 2013-02-20 |
| EP1761494B1 (en) | 2010-04-21 |
| NO20070431L (no) | 2007-03-26 |
| TW200610759A (en) | 2006-04-01 |
| ES2342181T3 (es) | 2010-07-02 |
| SE0401657D0 (sv) | 2004-06-24 |
| ZA200610526B (en) | 2008-08-27 |
| IL179729A0 (en) | 2007-05-15 |
| AU2005257707B2 (en) | 2009-03-26 |
| RU2006146877A (ru) | 2008-07-27 |
| CN101006058A (zh) | 2007-07-25 |
| JP2008503572A (ja) | 2008-02-07 |
| AR049830A1 (es) | 2006-09-06 |
| RU2381216C2 (ru) | 2010-02-10 |
| EP1761494A1 (en) | 2007-03-14 |
| UY28974A1 (es) | 2006-01-31 |
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