BRPI0513534A - inibidores de proteìna 4 semelhante à angiopoietina, combinações, e seu uso - Google Patents

inibidores de proteìna 4 semelhante à angiopoietina, combinações, e seu uso

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Publication number
BRPI0513534A
BRPI0513534A BRPI0513534-6A BRPI0513534A BRPI0513534A BR PI0513534 A BRPI0513534 A BR PI0513534A BR PI0513534 A BRPI0513534 A BR PI0513534A BR PI0513534 A BRPI0513534 A BR PI0513534A
Authority
BR
Brazil
Prior art keywords
angiopoietin
protein
combinations
inhibitors
cancer
Prior art date
Application number
BRPI0513534-6A
Other languages
English (en)
Inventor
Napoleone Ferrara
Hans-Peter Gerber
Xiao Huan Liang
Original Assignee
Genentech Inc
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35787710&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0513534(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BRPI0513534A publication Critical patent/BRPI0513534A/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
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  • Dermatology (AREA)
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  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
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Abstract

INIBIDORES DE PROTEìNA 4 SEMELHANTE à ANGIOPOIETINA, COMBINAçõES, E SEU USO. Os moduladores de proteína 4 semelhante à angiopoletina são fornecidos junto com métodos para seu uso no tratamento de doenças e condições patológicas. As combinações de antagonistas de ANGPTL4 e outros produtos terapêuticos, por exemplo, agentes anticâncer, e métodos de seu uso no tratamento de mamíferos suscetíveis ou diagnosticados com câncer, ou com crescimento de tumor reincidente ou crescimento de célula cancerosa reincidente também são fornecidos.
BRPI0513534-6A 2004-07-20 2005-07-19 inibidores de proteìna 4 semelhante à angiopoietina, combinações, e seu uso BRPI0513534A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58978204P 2004-07-20 2004-07-20
PCT/US2005/025734 WO2006014729A2 (en) 2004-07-20 2005-07-19 Inhibitors of angiopoietin-like 4 protein, combinations, and their use

Publications (1)

Publication Number Publication Date
BRPI0513534A true BRPI0513534A (pt) 2008-05-06

Family

ID=35787710

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0513534-6A BRPI0513534A (pt) 2004-07-20 2005-07-19 inibidores de proteìna 4 semelhante à angiopoietina, combinações, e seu uso

Country Status (23)

Country Link
US (2) US7740846B2 (pt)
EP (3) EP1771474B1 (pt)
JP (2) JP4947717B2 (pt)
KR (1) KR101254815B1 (pt)
CN (2) CN101044164A (pt)
AT (1) ATE456579T1 (pt)
AU (2) AU2005269716B2 (pt)
BR (1) BRPI0513534A (pt)
CA (1) CA2574758A1 (pt)
CY (1) CY1109931T1 (pt)
DE (1) DE602005019167D1 (pt)
DK (1) DK1771474T3 (pt)
ES (1) ES2339789T3 (pt)
IL (1) IL180725A0 (pt)
MX (1) MX2007000784A (pt)
NO (1) NO20070951L (pt)
NZ (1) NZ552956A (pt)
PL (1) PL1771474T3 (pt)
PT (1) PT1771474E (pt)
RU (1) RU2392966C2 (pt)
SI (1) SI1771474T1 (pt)
WO (1) WO2006014729A2 (pt)
ZA (1) ZA200701183B (pt)

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