BRPI0518824A2 - cartucho unitÁrio para processamento de partÍcula - Google Patents

cartucho unitÁrio para processamento de partÍcula

Info

Publication number
BRPI0518824A2
BRPI0518824A2 BRPI0518824-5A BRPI0518824A BRPI0518824A2 BR PI0518824 A2 BRPI0518824 A2 BR PI0518824A2 BR PI0518824 A BRPI0518824 A BR PI0518824A BR PI0518824 A2 BRPI0518824 A2 BR PI0518824A2
Authority
BR
Brazil
Prior art keywords
cartridge
particle
particle processing
processing
unit cartridge
Prior art date
Application number
BRPI0518824-5A
Other languages
English (en)
Inventor
John R Gilbert
Hugh Lewis
Derek Beaupre
Manish Deshpande
Jaishree Trikha
Original Assignee
Cytonome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytonome Inc filed Critical Cytonome Inc
Publication of BRPI0518824A2 publication Critical patent/BRPI0518824A2/pt
Publication of BRPI0518824B1 publication Critical patent/BRPI0518824B1/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D27/00—Cartridge filters of the throw-away type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/527—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1023—Microstructural devices for non-optical measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0636—Focussing flows, e.g. to laminate flows
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/08—Ergonomic or safety aspects of handling devices
    • B01L2200/082—Handling hazardous material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L5/00—Gas handling apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486—Counting the particles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Fluid Mechanics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

CARTUCHO UNITÁRIO PARA PROCESSAMENTO DE PARTÍCULA. Um único cartucho descartável para executar um processo em uma partícula, tal como separação de partícula, encapsula todas as superfícies de contato de fluído no cartucho para uso com tecnologia de processamento de partícula mícrofluidíca. As interfaces do cartucho com um sistema operacional para efetuar processamento de partícula. O encapsulamento pode empregar qualquer técnica adequada para processar partículas.
BRPI0518824-5A 2004-12-03 2005-12-05 "particle cartridge for particle processing and method of processing of a sample" BRPI0518824B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63339604P 2004-12-03 2004-12-03
US60/633,396 2004-12-03
PCT/US2005/043965 WO2006060783A2 (en) 2004-12-03 2005-12-05 Unitary cartridge for particle processing

Publications (2)

Publication Number Publication Date
BRPI0518824A2 true BRPI0518824A2 (pt) 2008-12-09
BRPI0518824B1 BRPI0518824B1 (pt) 2017-11-28

Family

ID=35920748

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0518824-5A BRPI0518824B1 (pt) 2004-12-03 2005-12-05 "particle cartridge for particle processing and method of processing of a sample"

Country Status (11)

Country Link
US (5) US8277764B2 (pt)
EP (2) EP1817568B1 (pt)
JP (1) JP5548337B2 (pt)
KR (1) KR20070104347A (pt)
CN (1) CN101099082B (pt)
AU (1) AU2005311631B2 (pt)
BR (1) BRPI0518824B1 (pt)
CA (1) CA2588753C (pt)
IL (1) IL183560A (pt)
WO (1) WO2006060783A2 (pt)
ZA (2) ZA200704952B (pt)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9943847B2 (en) 2002-04-17 2018-04-17 Cytonome/St, Llc Microfluidic system including a bubble valve for regulating fluid flow through a microchannel
US11243494B2 (en) 2002-07-31 2022-02-08 Abs Global, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
US7311476B2 (en) 2003-10-30 2007-12-25 Cytonome, Inc. Multilayer hydrodynamic sheath flow structure
CN101099082B (zh) 2004-12-03 2013-03-27 塞通诺米/St有限责任公司 用于粒子处理的整体式盒
US9260693B2 (en) 2004-12-03 2016-02-16 Cytonome/St, Llc Actuation of parallel microfluidic arrays
WO2007033669A1 (en) * 2005-09-22 2007-03-29 Chempaq A/S Detection and subsequent removal of an aperture blockage
EP2072132A1 (en) * 2007-12-20 2009-06-24 Koninklijke Philips Electronics N.V. Reactor system in particular for biochemical reactions
US20120164718A1 (en) * 2008-05-06 2012-06-28 Innovative Micro Technology Removable/disposable apparatus for MEMS particle sorting device
WO2010006174A2 (en) * 2008-07-10 2010-01-14 Reichenbach Steven H Method and apparatus for sorting particles using asymmetrical particle shifting
US20100161267A1 (en) * 2008-12-19 2010-06-24 Roche Diagnostics Operations, Inc. Device and Method for Automatic Calibration Verification of an Analyzer
US9645010B2 (en) 2009-03-10 2017-05-09 The Regents Of The University Of California Fluidic flow cytometry devices and methods
US9134221B2 (en) 2009-03-10 2015-09-15 The Regents Of The University Of California Fluidic flow cytometry devices and particle sensing based on signal-encoding
US20110020855A1 (en) * 2009-07-21 2011-01-27 Masataka Shinoda Method and apparatus for performing cytometry
WO2012054904A2 (en) 2010-10-21 2012-04-26 The Regents Of The University Of California Microfluidics with wirelessly powered electronic circuits
US10908066B2 (en) 2010-11-16 2021-02-02 1087 Systems, Inc. Use of vibrational spectroscopy for microfluidic liquid measurement
US8695618B2 (en) 2010-12-22 2014-04-15 Carnegie Mellon University 3D chemical pattern control in 2D fluidics devices
US8993311B2 (en) * 2011-01-21 2015-03-31 Innovative Micro Technology Multi-stage cartridge for MEMS particle storing system
US8822207B2 (en) 2011-01-21 2014-09-02 Owl biomedical, Inc. Cartridge for MEMS particle sorting system
WO2012148648A2 (en) 2011-04-27 2012-11-01 Becton Dickinson & Co. Devices and methods for separating magnetically labeled moieties in a sample
US9669403B2 (en) 2012-07-25 2017-06-06 Sony Corporation Microparticle measurement device and liquid delivery method in microparticle measurement device
US9529203B2 (en) 2012-09-17 2016-12-27 Cytonome/St, Llc Focal plane shifting system
CN110579435B (zh) 2012-10-15 2023-09-26 纳诺赛莱克特生物医药股份有限公司 颗粒分选的系统、设备和方法
CN104736718A (zh) 2012-10-26 2015-06-24 贝克顿·迪金森公司 用于操纵流体样品中的组分的装置和方法
JP6349327B2 (ja) 2012-12-17 2018-06-27 レウコドゥックス，リミテッド 化学的状態を判定するためのシステムおよび方法
US10610861B2 (en) 2012-12-17 2020-04-07 Accellix Ltd. Systems, compositions and methods for detecting a biological condition
US20140170678A1 (en) * 2012-12-17 2014-06-19 Leukodx Ltd. Kits, compositions and methods for detecting a biological condition
US9757726B2 (en) 2013-03-14 2017-09-12 Inguran, Llc System for high throughput sperm sorting
US10662408B2 (en) 2013-03-14 2020-05-26 Inguran, Llc Methods for high throughput sperm sorting
US9335247B2 (en) 2013-03-14 2016-05-10 Cytonome/St, Llc Assemblies and methods for reducing optical crosstalk in particle processing systems
US10371622B2 (en) 2013-03-14 2019-08-06 Inguran, Llc Device for high throughput sperm sorting
WO2014152039A2 (en) 2013-03-14 2014-09-25 Cytonome/St, Llc Operatorless particle processing systems and methods
NZ743491A (en) 2013-03-14 2020-03-27 Cytonome St Llc Hydrodynamic focusing apparatus and methods
US10190960B2 (en) 2013-03-14 2019-01-29 Cytonome/St, Llc Micro-lens systems for particle processing systems
US10272428B2 (en) 2013-04-30 2019-04-30 Hewlett-Packard Development Company, L.P. Microfluidic sensing device and system
US8961904B2 (en) 2013-07-16 2015-02-24 Premium Genetics (Uk) Ltd. Microfluidic chip
DE102013111778B3 (de) * 2013-10-25 2015-04-30 Bürkert Werke GmbH Mikrofluidische Geräteeinheit
US11796449B2 (en) 2013-10-30 2023-10-24 Abs Global, Inc. Microfluidic system and method with focused energy apparatus
JP6733909B2 (ja) 2013-10-30 2020-08-05 エービーエス グローバル インコーポレイテッド 複数の物質を識別する装置、複数の物質を識別するコンピュータシステム、複数の物質を識別するための複数の命令をコンピュータに実行させるプログラムおよびサンプル流体混合物中を流れる複数の物質を識別する方法
JP5951138B2 (ja) * 2014-03-07 2016-07-13 古河電気工業株式会社 スクリーニング装置およびスクリーニング方法
US10960396B2 (en) 2014-05-16 2021-03-30 Cytonome/St, Llc Thermal activated microfluidic switching
US10180388B2 (en) 2015-02-19 2019-01-15 1087 Systems, Inc. Scanning infrared measurement system
US20180163713A1 (en) 2015-06-23 2018-06-14 Nanocellect Biomedical, Inc. Systems, apparatuses, and methods for cell sorting and flow cytometry
WO2017087707A1 (en) * 2015-11-18 2017-05-26 Beckman Coulter, Inc. Filtering device for analyzing instrument
EP4309789A3 (en) * 2016-03-17 2024-08-21 Kazemzadeh, Amin Microfluidic on-chip storage devices
US10471425B2 (en) * 2017-02-16 2019-11-12 International Business Machines Corporation Automated machine for sorting of biological fluids
WO2018175411A1 (en) 2017-03-20 2018-09-27 Nanocellect Biomedical, Inc. Systems, apparatuses, and methods for cell sorting and flow cytometry
USD868991S1 (en) 2017-03-28 2019-12-03 Becton, Dickinson And Company Register block
USD869676S1 (en) 2017-03-28 2019-12-10 Becton, Dickinson And Company Particle sorting module
WO2018200123A1 (en) 2017-04-28 2018-11-01 Becton, Dickinson And Company Particle detection cartridges, systems thereof and methods for using the same
JP6985508B2 (ja) * 2017-09-30 2021-12-22 インスクリプタ， インコーポレイテッド フロースルーエレクトロポレーション機器編成
USD882817S1 (en) 2018-01-30 2020-04-28 Becton, Dickinson And Company Sample container
USD872296S1 (en) 2018-01-30 2020-01-07 Becton, Dickinson And Company Particle sorting module
USD876668S1 (en) 2018-01-30 2020-02-25 Becton, Dickinson And Company Particle sorting module mount
USD864415S1 (en) 2018-01-30 2019-10-22 Becton, Dickinson And Company Particle sorting system
US11331670B2 (en) 2018-05-23 2022-05-17 Abs Global, Inc. Systems and methods for particle focusing in microchannels
SE542462C2 (en) 2018-09-20 2020-05-12 Astrego Diagnostics Ab Sample loading cartridge for a microfluidic device
CN113272648A (zh) * 2018-10-25 2021-08-17 萨夫兰技术公司 粒子捕获系统和方法
EP3899489B1 (en) 2018-12-21 2025-04-09 ABS Global, Inc. System and methods for sub-population identification
EP3955735B1 (en) 2019-04-18 2024-05-22 ABS Global, Inc. System and process for continuous addition of cryoprotectant
US11628439B2 (en) 2020-01-13 2023-04-18 Abs Global, Inc. Single-sheath microfluidic chip
WO2022087299A1 (en) 2020-10-21 2022-04-28 Abs Global, Inc. Methods and systems for processing genetic samples to determine identity or detect contamination
US12135270B2 (en) 2020-11-23 2024-11-05 Abs Global, Inc. Modular flow cytometry systems and methods of processing samples
WO2022226791A1 (zh) * 2021-04-27 2022-11-03 京东方科技集团股份有限公司 芯片、微流控装置以及分选目标液滴的方法
GB2621756B (en) 2021-04-27 2026-04-01 Boe Technology Group Co Ltd Microfluidic chip, box body device, and microfluidic device
USD1118965S1 (en) 2021-11-12 2026-03-17 Abs Global, Inc. Flow cytometry device

Family Cites Families (119)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4004150A (en) 1975-05-01 1977-01-18 Samuel Natelson Analytical multiple component readout system
JPS57132038A (en) 1981-02-10 1982-08-16 Olympus Optical Co Ltd Photometric device
US4498782A (en) 1981-05-29 1985-02-12 Science Research Center, Inc. Assembly for determining light transmissiveness of a fluid
JPS5857560A (ja) 1981-09-30 1983-04-05 Fuji Heavy Ind Ltd オイルシ−ル用エアブリ−ザ機構
GB2116740B (en) 1982-02-27 1985-08-29 Bergstroem Arne Objectives comprising pinhole aperture and image intensifier
US4651564A (en) 1982-09-30 1987-03-24 Honeywell Inc. Semiconductor device
US4501144A (en) 1982-09-30 1985-02-26 Honeywell Inc. Flow sensor
US4478076A (en) 1982-09-30 1984-10-23 Honeywell Inc. Flow sensor
US4478077A (en) 1982-09-30 1984-10-23 Honeywell Inc. Flow sensor
JPS60153023A (ja) 1984-01-23 1985-08-12 Toshiba Corp 高出力レ−ザ用ビ−ムスプリツタ装置
US4797696A (en) 1985-07-24 1989-01-10 Ateq Corporation Beam splitting apparatus
EP0286088B1 (en) * 1987-04-08 1994-09-14 Hitachi, Ltd. A sheath flow type flow-cell device
DE3831630A1 (de) 1988-09-17 1990-03-22 Ulrich M Landwehr Verfahren und vorrichtung zur ermittlung der abmessungen eines gegenstandes auf photographischem wege
US5082242A (en) 1989-12-27 1992-01-21 Ulrich Bonne Electronic microvalve apparatus and fabrication
US5244537A (en) 1989-12-27 1993-09-14 Honeywell, Inc. Fabrication of an electronic microvalve apparatus
US5050429A (en) 1990-02-22 1991-09-24 Yamatake-Honeywell Co., Ltd. Microbridge flow sensor
FI86340C (fi) 1990-10-31 1992-08-10 Labsystems Oy Foerfarande foer ledning av ljus.
US5108623A (en) 1990-11-19 1992-04-28 Gould Inc. Moving web filter assembly
US5176358A (en) 1991-08-08 1993-01-05 Honeywell Inc. Microstructure gas valve control
JPH05157684A (ja) 1991-12-02 1993-06-25 Seikagaku Kogyo Co Ltd 吸光光度計
US5441597A (en) 1992-12-01 1995-08-15 Honeywell Inc. Microstructure gas valve control forming method
DE69424236T2 (de) 1993-09-16 2000-11-30 Owens-Brockway Glass Container Inc., Toledo Prüfung von durchsichtigen Behältern
JP2948069B2 (ja) * 1993-09-20 1999-09-13 株式会社日立製作所 化学分析装置
GB9406551D0 (en) 1994-03-31 1994-05-25 Hjelm Nils M Chromatography system and methodology
JPH07286953A (ja) 1994-04-19 1995-10-31 Toa Medical Electronics Co Ltd イメージングフローサイトメータ
ATE269160T1 (de) * 1994-11-14 2004-07-15 Univ Pennsylvania Miniaturisierte probenvorbereitungsvorrichtungen sowie systeme zur feststellung und behandlung von analyten
DE19520298A1 (de) 1995-06-02 1996-12-05 Bayer Ag Sortiervorrichtung für biologische Zellen oder Viren
US5922210A (en) 1995-06-16 1999-07-13 University Of Washington Tangential flow planar microfabricated fluid filter and method of using thereof
US5716852A (en) 1996-03-29 1998-02-10 University Of Washington Microfabricated diffusion-based chemical sensor
US5932100A (en) 1995-06-16 1999-08-03 University Of Washington Microfabricated differential extraction device and method
JP3515646B2 (ja) 1995-09-18 2004-04-05 大塚電子株式会社 マルチキャピラリ電気泳動装置
US5726751A (en) 1995-09-27 1998-03-10 University Of Washington Silicon microchannel optical flow cytometer
JP3308441B2 (ja) 1995-12-19 2002-07-29 シスメックス株式会社 尿中有形成分分析装置
US5863502A (en) 1996-01-24 1999-01-26 Sarnoff Corporation Parallel reaction cassette and associated devices
US5851488A (en) * 1996-02-29 1998-12-22 Biocircuits Corporation Apparatus for automatic electro-optical chemical assay determination
US5948684A (en) 1997-03-31 1999-09-07 University Of Washington Simultaneous analyte determination and reference balancing in reference T-sensor devices
US6361672B1 (en) 1996-06-10 2002-03-26 Transgenomic, Inc. Multiple laser diode electromagnetic radiation source in multiple electrophoresis channel systems
DE69728269T2 (de) 1996-06-14 2005-03-10 University Of Washington, Seattle Absorbtionsverbessertes differentielles extraktionsverfahren
US5764674A (en) 1996-06-28 1998-06-09 Honeywell Inc. Current confinement for a vertical cavity surface emitting laser
JP3834357B2 (ja) * 1996-07-10 2006-10-18 オリンパス株式会社 小型分析装置及びその駆動方法
US5699157A (en) 1996-07-16 1997-12-16 Caliper Technologies Corp. Fourier detection of species migrating in a microchannel
US5799030A (en) 1996-07-26 1998-08-25 Honeywell Inc. Semiconductor device with a laser and a photodetector in a common container
US5683159A (en) 1997-01-03 1997-11-04 Johnson; Greg P. Hardware mounting rail
US6445448B1 (en) 1997-03-12 2002-09-03 Corning Applied Technologies, Corp. System and method for molecular sample measurement
US6252715B1 (en) 1997-03-13 2001-06-26 T. Squared G, Inc. Beam pattern contractor and focus element, method and apparatus
EP1021566A4 (en) 1997-06-09 2002-06-19 Caliper Techn Corp DEVICE AND METHOD FOR CORRECTING VARIOUS SPEEDS IN MICROFLUIDIC SYSTEMS
US5974867A (en) 1997-06-13 1999-11-02 University Of Washington Method for determining concentration of a laminar sample stream
DE19725050C2 (de) 1997-06-13 1999-06-24 Fraunhofer Ges Forschung Anordnung zur Detektion biochemischer oder chemischer Substanzen mittels Fluoreszenzlichtanregung und Verfahren zu deren Herstellung
US6001231A (en) 1997-07-15 1999-12-14 Caliper Technologies Corp. Methods and systems for monitoring and controlling fluid flow rates in microfluidic systems
US5876266A (en) 1997-07-15 1999-03-02 International Business Machines Corporation Polishing pad with controlled release of desired micro-encapsulated polishing agents
US6082185A (en) 1997-07-25 2000-07-04 Research International, Inc. Disposable fluidic circuit cards
EP1003759A2 (en) * 1997-08-13 2000-05-31 Cepheid Microstructures for the manipulation of fluid samples
US6007775A (en) 1997-09-26 1999-12-28 University Of Washington Multiple analyte diffusion based chemical sensor
JPH11108838A (ja) 1997-10-06 1999-04-23 Horiba Ltd 濁度測定方法および濁度測定器
US5836750A (en) 1997-10-09 1998-11-17 Honeywell Inc. Electrostatically actuated mesopump having a plurality of elementary cells
US5822170A (en) 1997-10-09 1998-10-13 Honeywell Inc. Hydrophobic coating for reducing humidity effect in electrostatic actuators
AU1517999A (en) * 1997-10-15 1999-05-03 Aclara Biosciences, Inc. Laminate microstructure device and method for making same
EP1179585B1 (en) * 1997-12-24 2008-07-09 Cepheid Device and method for lysis
US6756019B1 (en) 1998-02-24 2004-06-29 Caliper Technologies Corp. Microfluidic devices and systems incorporating cover layers
US6100541A (en) 1998-02-24 2000-08-08 Caliper Technologies Corporation Microfluidic devices and systems incorporating integrated optical elements
DE69903800T2 (de) 1998-03-18 2003-10-02 Massachusetts Institute Of Technology, Cambridge Vaskularisierte perfundierte anordnungen für mikrogewebe und mikroorgane
US6719868B1 (en) 1998-03-23 2004-04-13 President And Fellows Of Harvard College Methods for fabricating microfluidic structures
CA2320296A1 (en) 1998-05-18 1999-11-25 University Of Washington Liquid analysis cartridge
JP3522535B2 (ja) 1998-05-29 2004-04-26 忠弘 大見 圧力式流量制御装置を備えたガス供給設備
WO2000006996A1 (en) 1998-07-28 2000-02-10 Ce Resources Pte Ltd. Optical detection system
US6103199A (en) 1998-09-15 2000-08-15 Aclara Biosciences, Inc. Capillary electroflow apparatus and method
US6496260B1 (en) 1998-12-23 2002-12-17 Molecular Devices Corp. Vertical-beam photometer for determination of light absorption pathlength
US6608682B2 (en) 1999-01-25 2003-08-19 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US6097485A (en) 1999-03-08 2000-08-01 Integrated Waveguides, Inc. Microchip optical transport technology for use in a personal flow cytometer
US20020177135A1 (en) * 1999-07-27 2002-11-28 Doung Hau H. Devices and methods for biochip multiplexing
EP1179087B1 (en) * 1999-05-17 2019-03-27 Caliper Life Sciences, Inc. Focusing of microparticles in microfluidic systems
US6592821B1 (en) 1999-05-17 2003-07-15 Caliper Technologies Corp. Focusing of microparticles in microfluidic systems
US6878540B2 (en) * 1999-06-25 2005-04-12 Cepheid Device for lysing cells, spores, or microorganisms
US6353475B1 (en) 1999-07-12 2002-03-05 Caliper Technologies Corp. Light source power modulation for use with chemical and biochemical analysis
AU1325201A (en) 1999-07-16 2001-02-05 Board Of Regents, The University Of Texas System Detection system based on an analyte reactive particle
EP1242813A4 (en) 1999-07-28 2002-10-30 Univ Washington INTERCONNECTION SYSTEM FOR FLUIDS, INTERCONNECTION TUBING AND MICROFLUIDIC DEVICES FOR INTERNAL GAS DISTRIBUTION AND APPLICATION OF A VACUUM
CA2364381C (en) * 1999-12-22 2009-03-10 Gene Logic, Inc. Flow-thru chip cartridge, chip holder, system and method thereof
ATE403145T1 (de) 2000-01-31 2008-08-15 Univ Texas Tragbare vorrichtung mit einer sensor-array- anordnung
US6325114B1 (en) * 2000-02-01 2001-12-04 Incyte Genomics, Inc. Pipetting station apparatus
US6597438B1 (en) 2000-08-02 2003-07-22 Honeywell International Inc. Portable flow cytometry
US7351376B1 (en) 2000-06-05 2008-04-01 California Institute Of Technology Integrated active flux microfluidic devices and methods
US6632400B1 (en) 2000-06-22 2003-10-14 Agilent Technologies, Inc. Integrated microfluidic and electronic components
US6567163B1 (en) 2000-08-17 2003-05-20 Able Signal Company Llc Microarray detector and synthesizer
US6827095B2 (en) 2000-10-12 2004-12-07 Nanostream, Inc. Modular microfluidic systems
AU2002230592A1 (en) 2000-10-27 2002-05-06 Molecular Devices Corporation Light detection device
US6744038B2 (en) 2000-11-13 2004-06-01 Genoptix, Inc. Methods of separating particles using an optical gradient
US6824024B2 (en) 2000-11-17 2004-11-30 Tecan Trading Ag Device for the take-up and/or release of liquid samples
JP4862108B2 (ja) 2001-02-02 2012-01-25 株式会社森精機製作所 受発光複合ユニット及びこれを用いた変位検出装置
DE10111457B4 (de) * 2001-03-09 2006-12-14 Siemens Ag Diagnoseeinrichtung
WO2002081934A2 (en) 2001-04-03 2002-10-17 Micronics, Inc. Pneumatic valve interface for use in microfluidic structures
US20030027225A1 (en) * 2001-07-13 2003-02-06 Caliper Technologies Corp. Microfluidic devices and systems for separating components of a mixture
US7338760B2 (en) * 2001-10-26 2008-03-04 Ntu Ventures Private Limited Sample preparation integrated chip
WO2003054524A1 (en) 2001-12-11 2003-07-03 Sau Lan Tang Staats Microfluidic devices and methods for two-dimensional separations
US7312085B2 (en) * 2002-04-01 2007-12-25 Fluidigm Corporation Microfluidic particle-analysis systems
EP1499453B1 (en) * 2002-04-17 2016-01-06 Cytonome/ST, LLC Apparatus for sorting particles
US6976590B2 (en) 2002-06-24 2005-12-20 Cytonome, Inc. Method and apparatus for sorting particles
US7157274B2 (en) * 2002-06-24 2007-01-02 Cytonome, Inc. Method and apparatus for sorting particles
US6808075B2 (en) 2002-04-17 2004-10-26 Cytonome, Inc. Method and apparatus for sorting particles
WO2003104771A1 (en) * 2002-06-01 2003-12-18 Chempaq A/S Lysing reagent, cartridge and automatic electronic cell counter for simultaneous enumeration of different types of white blood cells
JP4704036B2 (ja) * 2002-06-11 2011-06-15 ケムパック エイ／エス 液体中に懸濁された粒子を特徴付けるための使い捨てカートリッジ
US6838056B2 (en) 2002-07-08 2005-01-04 Innovative Micro Technology Method and apparatus for sorting biological cells with a MEMS device
US7220594B2 (en) 2002-07-08 2007-05-22 Innovative Micro Technology Method and apparatus for sorting particles with a MEMS device
US20040011650A1 (en) * 2002-07-22 2004-01-22 Frederic Zenhausern Method and apparatus for manipulating polarizable analytes via dielectrophoresis
US20040017570A1 (en) 2002-07-23 2004-01-29 Bhairavi Parikh Device and system for the quantification of breath gases
AU2003303303A1 (en) * 2002-08-19 2004-08-30 Bioprocessors Corporation Microreactor architecture and methods
US20040086872A1 (en) * 2002-10-31 2004-05-06 Childers Winthrop D. Microfluidic system for analysis of nucleic acids
US7476363B2 (en) 2003-04-03 2009-01-13 Fluidigm Corporation Microfluidic devices and methods of using same
US7298478B2 (en) 2003-08-14 2007-11-20 Cytonome, Inc. Optical detector for a particle sorting system
FR2865145B1 (fr) 2004-01-19 2006-02-24 Commissariat Energie Atomique Dispositif de dispense de gouttelettes microfluidiques notamment pour la cytometrie.
US7612871B2 (en) 2004-09-01 2009-11-03 Honeywell International Inc Frequency-multiplexed detection of multiple wavelength light for flow cytometry
CN101099082B (zh) 2004-12-03 2013-03-27 塞通诺米/St有限责任公司 用于粒子处理的整体式盒
US9260693B2 (en) 2004-12-03 2016-02-16 Cytonome/St, Llc Actuation of parallel microfluidic arrays
WO2007001522A2 (en) 2005-06-17 2007-01-04 Nusci Laboratories Llc Stabilization of oxidized fats
JP4512698B2 (ja) 2005-08-30 2010-07-28 ナノフォトン株式会社 レーザ顕微鏡
DE102005054923B3 (de) 2005-11-17 2007-04-12 Siemens Ag Vorrichtung und Verfahren zur Aufbereitung einer Probe
US8691164B2 (en) 2007-04-20 2014-04-08 Celula, Inc. Cell sorting system and methods
CN110579435B (zh) 2012-10-15 2023-09-26 纳诺赛莱克特生物医药股份有限公司 颗粒分选的系统、设备和方法
NZ743491A (en) 2013-03-14 2020-03-27 Cytonome St Llc Hydrodynamic focusing apparatus and methods
US9757726B2 (en) 2013-03-14 2017-09-12 Inguran, Llc System for high throughput sperm sorting

Also Published As

Publication number Publication date
US20120009619A1 (en) 2012-01-12
CA2588753A1 (en) 2006-06-08
IL183560A (en) 2014-12-31
US10794913B2 (en) 2020-10-06
US8277764B2 (en) 2012-10-02
IL183560A0 (en) 2007-09-20
ZA200806181B (en) 2009-05-27
JP5548337B2 (ja) 2014-07-16
EP2423667B1 (en) 2021-03-03
WO2006060783A3 (en) 2006-09-14
US20140170673A1 (en) 2014-06-19
WO2006060783A2 (en) 2006-06-08
EP1817568B1 (en) 2019-04-17
CA2588753C (en) 2014-02-18
CN101099082B (zh) 2013-03-27
AU2005311631A1 (en) 2006-06-08
US20060269446A1 (en) 2006-11-30
JP2008522793A (ja) 2008-07-03
US20190195876A1 (en) 2019-06-27
EP2423667A3 (en) 2012-05-30
EP1817568A2 (en) 2007-08-15
EP2423667A2 (en) 2012-02-29
CN101099082A (zh) 2008-01-02
US9823252B2 (en) 2017-11-21
US20180074060A1 (en) 2018-03-15
US10222378B2 (en) 2019-03-05
US8679422B2 (en) 2014-03-25
AU2005311631B2 (en) 2012-06-07
KR20070104347A (ko) 2007-10-25
ZA200704952B (en) 2008-11-26
BRPI0518824B1 (pt) 2017-11-28

Similar Documents

Publication Publication Date Title
BRPI0518824A2 (pt) cartucho unitÁrio para processamento de partÍcula
WO2006032044A3 (en) Microfluidic devices
BRPI0606842A2 (pt) separador de aerossol
BRPI0613303A8 (pt) composições que contêm pufa e/ou uridina e métodos de uso das mesmas
EP4674980A3 (en) Spatially encoded biological assays using a microfluidic device
ATE462493T1 (de) Integriertes system mit modularen mikrofluidischen komponenten
WO2014152048A3 (en) Assemblies and methods for reducing optical crosstalk in particle processing systems
BRPI0919207A2 (pt) método e sistema implementado por computador para uso na modelagem de um sistema de reservatório geomecânico, e , método implementado por computador para uso na modelagem de uma ruptura.
ATE447923T1 (de) System und vorrichtung zum entnehmen von pharmazeutika
CL2012001637A1 (es) Compuestos derivados de bi-(5-fenil-2-(pirrolidin-2-il)-1h-imidazol), con actividad inhibidora de la funcion de la proteina ns5a codificada por el virus de la hepatitis c (vhc), composición farmacéutica que los comprende; uso en el tratamiento de la hepatitis c.
WO2011017082A3 (en) Assay information management methods and devices
WO2008039918A3 (en) Methods and apparatus for hybrid outlier detection
MX2009000468A (es) Metodos y sistemas para confirmacion e incentivos de cumplimiento.
WO2008073161A3 (en) Hemagglutinin polypeptides, and reagents and methods relating thereto
BRPI0713196A2 (pt) sistema de autanticação de uma usuário virtual e método de autenticação de um usuário
HK1253950A1 (zh) 经由纳米压印的选择性表面图案化
WO2007070455A3 (en) Mesporous carbons
AR076275A1 (es) Uso de una tierra rara para la remocion de antimonio y bismuto
ATE505725T1 (de) Nukleinsäuredetektion mit poröser polymerelektrode
WO2012085884A8 (en) Microfluidic device for manipulating particles
WO2015017801A8 (en) System for nanoanalysis
TW200724500A (en) Fine particle of salt, hydroxide or oxide, and the method for manufacturing the same
FI20085628A7 (fi) Menetelmä ja laitteisto nestevirtauksen tutkimiseksi mikrofluidistisessa järjestelmässä
BR112014001668A2 (pt) sistema e método para ativar um dispositivo móvel para iniciar uma comunicação direcionada a um dispositivo-alvo, e, dispositivo móvel capaz de iniciar uma comunicação com um dispositivo-alvo
WO2012040473A3 (en) Solution microarrays and uses thereof

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: CYTONOME/ST, LLC (US)

Free format text: TRANSFERIDO DE: CYTONOME, INC.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B25G Requested change of headquarter approved