BRPI0519165A2 - unidade de expressço, cassete de expressço, vetor, microorganismo geneticamente modificado, processo para preparar um produto biossintÉtico, e, uso de uma unidade de expressço - Google Patents

unidade de expressço, cassete de expressço, vetor, microorganismo geneticamente modificado, processo para preparar um produto biossintÉtico, e, uso de uma unidade de expressço

Info

Publication number
BRPI0519165A2
BRPI0519165A2 BRPI0519165-3A BRPI0519165A BRPI0519165A2 BR PI0519165 A2 BRPI0519165 A2 BR PI0519165A2 BR PI0519165 A BRPI0519165 A BR PI0519165A BR PI0519165 A2 BRPI0519165 A2 BR PI0519165A2
Authority
BR
Brazil
Prior art keywords
expression unit
vector
expression
genetically modified
preparing
Prior art date
Application number
BRPI0519165-3A
Other languages
English (en)
Inventor
Stefan Hafner
Corinna Klopprogge
Andrea Herold
Hartwig Schroeder
Oskar Zelder
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36052084&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0519165(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Basf Ag filed Critical Basf Ag
Publication of BRPI0519165A2 publication Critical patent/BRPI0519165A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

UNIDADE DE EXPRESSçO, CASSETE DE EXPRESSçO, VETOR, MICROORGANISMO GENETICAMENTE MODIFICADO, PROCESSO PARA PREPARAR UM PRODUTO BIOSSINTETICO, E, USO DE UMA UNIDADE DE EXPRESSçO. A invenção diz respeito a promotores múltiplos e unidades de expressão de gene, ao uso destes para regular a transcrição e expressão de gene, aos cassetes de expressão contendo os ditos promotores múltiplos ou unidades de expressão, aos vetores contendo os ditos cassetes de expressão, aos microorganismos geneticamente modificados contendo os ditos vetores e/ou as ditas unidades de expressão e aos métodos para preparar produtos biossintéticos pelo cultivo de microorganismos geneticamente modificados.
BRPI0519165-3A 2004-12-22 2005-12-21 unidade de expressço, cassete de expressço, vetor, microorganismo geneticamente modificado, processo para preparar um produto biossintÉtico, e, uso de uma unidade de expressço BRPI0519165A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004061846A DE102004061846A1 (de) 2004-12-22 2004-12-22 Mehrfachpromotoren
PCT/EP2005/013809 WO2006069711A1 (de) 2004-12-22 2005-12-21 Mehrfachpromotoren und deren verwendung zur genexpression

Publications (1)

Publication Number Publication Date
BRPI0519165A2 true BRPI0519165A2 (pt) 2008-12-30

Family

ID=36052084

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0520842-4A BRPI0520842A2 (pt) 2004-12-22 2005-12-21 unidade de expressão recombinante compreendendo promotor múltiplo, cassete de expressão, vetor, microorganismo geneticamente modificado, processo para preparar um produto biossintético diferente de lisina, e, uso de uma unidade de expressão
BRPI0519165-3A BRPI0519165A2 (pt) 2004-12-22 2005-12-21 unidade de expressço, cassete de expressço, vetor, microorganismo geneticamente modificado, processo para preparar um produto biossintÉtico, e, uso de uma unidade de expressço

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BRPI0520842-4A BRPI0520842A2 (pt) 2004-12-22 2005-12-21 unidade de expressão recombinante compreendendo promotor múltiplo, cassete de expressão, vetor, microorganismo geneticamente modificado, processo para preparar um produto biossintético diferente de lisina, e, uso de uma unidade de expressão

Country Status (17)

Country Link
US (1) US7968699B2 (pt)
EP (2) EP1908841B1 (pt)
JP (2) JP2008523834A (pt)
KR (1) KR101155461B1 (pt)
CN (2) CN101230345B (pt)
AT (1) ATE542906T1 (pt)
AU (1) AU2005321577A1 (pt)
BR (2) BRPI0520842A2 (pt)
CA (1) CA2591311A1 (pt)
DE (1) DE102004061846A1 (pt)
DK (1) DK1908841T3 (pt)
ES (1) ES2380000T3 (pt)
MX (1) MX2007007392A (pt)
PL (1) PL1908841T3 (pt)
RU (1) RU2007127792A (pt)
WO (1) WO2006069711A1 (pt)
ZA (1) ZA200704451B (pt)

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WO2008101857A2 (en) 2007-02-19 2008-08-28 Evonik Degussa Gmbh Coryneform bacteria with formate-thf-synthetase and/or glycine cleavage activity
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DE102009030342A1 (de) 2009-06-25 2010-12-30 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von organisch chemischen Verbindungen
CN106906175A (zh) 2009-12-17 2017-06-30 巴斯夫欧洲公司 用于生产尸胺的方法和重组微生物
DE102010003419B4 (de) 2010-03-30 2019-09-12 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von L-Ornithin
KR101922742B1 (ko) 2011-02-22 2019-02-20 바스프 에스이 카다베린의 생산을 위한 방법 및 재조합 미생물
DE102011006716A1 (de) 2011-04-04 2012-10-04 Evonik Degussa Gmbh Mikroorganismus und Verfahren zur fermentativen Herstellung einer organisch-chemischen Verbindung
DE102011118019A1 (de) 2011-06-28 2013-01-03 Evonik Degussa Gmbh Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens
BR112014021439B1 (pt) 2012-04-27 2021-12-21 Evonik Technochemie Gmbh Polipeptídeo de isopropilmalato sintase e a sequência de nucleotídeos que o codifica, vetor, microrganismo do gênero corynebacterium e uso do mesmo, bem como processo fermentativo para a produção de kic ou l-leucina
US20150353940A1 (en) * 2013-08-05 2015-12-10 Absci, Llc Vectors for use in an inducible coexpression system
EP2762571A1 (de) 2013-01-30 2014-08-06 Evonik Industries AG Mikroorganismus und Verfahren zur fermentativen Herstellung von Aminosäuren
HUE032752T2 (en) 2013-06-03 2017-10-30 Evonik Degussa Gmbh A method for the preparation of L-valine using recombinant corynebacteria containing propionate-inducible ilvBN operon
EP3014270A4 (en) * 2013-06-26 2017-03-01 Phylogica Limited Method of monitoring cellular trafficking of peptides
CN104845923B (zh) * 2014-02-14 2018-03-23 中国科学院微生物研究所 生产l‑组氨酸的方法及其专用重组菌
CN105779447B (zh) * 2014-12-22 2018-09-14 中国科学院大连化学物理研究所 3-磷酸甘油醛脱氢酶启动子和终止子及其应用
CN105779445B (zh) * 2014-12-22 2018-09-28 中国科学院大连化学物理研究所 果糖-1,6-二磷酸醛缩酶启动子和终止子及其应用
CN105779446B (zh) * 2014-12-22 2018-09-14 中国科学院大连化学物理研究所 3-磷酸甘油酸激酶启动子和终止子及其应用
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
CA3007635A1 (en) 2015-12-07 2017-06-15 Zymergen Inc. Promoters from corynebacterium glutamicum
US9988624B2 (en) 2015-12-07 2018-06-05 Zymergen Inc. Microbial strain improvement by a HTP genomic engineering platform
US11208649B2 (en) 2015-12-07 2021-12-28 Zymergen Inc. HTP genomic engineering platform
JP2019519241A (ja) 2016-06-30 2019-07-11 ザイマージェン インコーポレイテッド グルコース透過酵素ライブラリーを生成するための方法およびその使用
KR102345899B1 (ko) 2016-06-30 2021-12-31 지머젠 인코포레이티드 박테리아 헤모글로빈 라이브러리를 생성하는 방법 및 이의 용도
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
AU2018205001B2 (en) * 2016-12-30 2020-02-20 Ntxbio, Llc Cell-free expression system having novel inorganic polyphosphate-based energy regeneration
CN110869504A (zh) 2017-06-07 2020-03-06 齐默尔根公司 来自谷氨酸棒状杆菌的启动子及其在调节辅助基因表达中的用途
CN109142578B (zh) * 2018-09-12 2021-08-10 中国人民解放军军事科学院军事医学研究院 检测生物细胞中两种基因对目标代谢物调控关系的方法
JP7498598B2 (ja) * 2020-05-29 2024-06-12 花王株式会社 新規プロモーター
CN115322990B (zh) * 2021-05-10 2024-09-20 中国科学院天津工业生物技术研究所 具有启动子活性的多核苷酸及其在生产目标化合物中的用途
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KR102632294B1 (ko) 2021-08-27 2024-02-01 성균관대학교산학협력단 코리네박테리움 글루타미쿰의 모듈화 클로닝을 위한 프로모터 라이브러리 및 터미네이터 라이브러리, 및 이의 용도
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Also Published As

Publication number Publication date
EP1908841A1 (de) 2008-04-09
CN101230345B (zh) 2013-03-20
JP2008212157A (ja) 2008-09-18
PL1908841T3 (pl) 2012-07-31
JP2008523834A (ja) 2008-07-10
EP1908841B1 (de) 2012-01-25
MX2007007392A (es) 2007-07-16
CN101087883A (zh) 2007-12-12
AU2005321577A1 (en) 2006-07-06
ES2380000T3 (es) 2012-05-07
CN101230345A (zh) 2008-07-30
JP4763017B2 (ja) 2011-08-31
ZA200704451B (en) 2009-05-27
DK1908841T3 (da) 2012-05-14
KR20070092745A (ko) 2007-09-13
RU2007127792A (ru) 2009-01-27
DE102004061846A1 (de) 2006-07-13
WO2006069711A1 (de) 2006-07-06
BRPI0520842A2 (pt) 2012-07-03
US7968699B2 (en) 2011-06-28
KR101155461B1 (ko) 2012-09-07
ATE542906T1 (de) 2012-02-15
US20080268502A1 (en) 2008-10-30
EP1831374A1 (de) 2007-09-12
CA2591311A1 (en) 2006-07-06

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