BRPI0607604A2 - gene sms 13 - Google Patents
gene sms 13Info
- Publication number
- BRPI0607604A2 BRPI0607604A2 BRPI0607604-1A BRPI0607604A BRPI0607604A2 BR PI0607604 A2 BRPI0607604 A2 BR PI0607604A2 BR PI0607604 A BRPI0607604 A BR PI0607604A BR PI0607604 A2 BRPI0607604 A2 BR PI0607604A2
- Authority
- BR
- Brazil
- Prior art keywords
- polynucleotides
- production
- vitamin
- relates
- polypeptides
- Prior art date
Links
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 7
- 102000040430 polynucleotide Human genes 0.000 abstract 7
- 108091033319 polynucleotide Proteins 0.000 abstract 7
- 239000002157 polynucleotide Substances 0.000 abstract 7
- 238000004519 manufacturing process Methods 0.000 abstract 4
- 244000005700 microbiome Species 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 abstract 2
- 229930003268 Vitamin C Natural products 0.000 abstract 2
- 229960005070 ascorbic acid Drugs 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000011718 vitamin C Substances 0.000 abstract 2
- 235000019154 vitamin C Nutrition 0.000 abstract 2
- 239000002211 L-ascorbic acid Substances 0.000 abstract 1
- 235000000069 L-ascorbic acid Nutrition 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/58—Aldonic, ketoaldonic or saccharic acids
- C12P7/60—2-Ketogulonic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
GENE SMS 13. A presente invenção relaciona-se a genes recentemente identificados que codificam proteínas que estão envolvidas na síntese de ácido L-ascórbico (aqui também referido como Vitamina C). A invenção também apresenta polinucleotídeos que compreendem as seqúências de polinucleotídeos de comprimento total dos novos genes e fragmentos dessa, os novos polipeptídeos codificados pelos polinucleotídeos e fragmentos desses, bem como seus equivalentes funcionais. A presente invenção também relaciona-se ao uso dos referidos polinucleotídeos e polipeptídeos como ferramentas biotecnológicas na produção de Vitamina C a partir de microorganismos, pelo qual a modificação do referido polinucleotídeos e/ou polipeptídeos codificados tem um impacto direto ou indireto sobre o rendimento, produção e/ou eficiência de produção do produto de fermentação no referido microorganismo. Também são incluídos métodos/processos de uso dos polinucleotídeos e seqúências de polinucleotídeos modificadas para transformar microorganismos hospedeiros. A invenção também relaciona-se a microorganismos geneticamente construídos e a seu uso para a produção direta de Vitamina c.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05405120 | 2005-02-11 | ||
| EP05405066 | 2005-02-11 | ||
| PCT/EP2006/001210 WO2006084715A1 (en) | 2005-02-11 | 2006-02-10 | Gene sms 13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0607604A2 true BRPI0607604A2 (pt) | 2009-09-15 |
Family
ID=36571410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0607604-1A BRPI0607604A2 (pt) | 2005-02-11 | 2006-02-10 | gene sms 13 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20100151516A1 (pt) |
| EP (1) | EP1853701A1 (pt) |
| BR (1) | BRPI0607604A2 (pt) |
| WO (1) | WO2006084715A1 (pt) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1073155C (zh) * | 1994-02-25 | 2001-10-17 | 藤泽药品工业株式会社 | 2－酮－l－古洛糖酸的生产方法 |
| CA2239802A1 (en) * | 1997-08-21 | 1999-02-21 | F. Hoffmann-La Roche Ag | D-sorbitol dehydrogenase gene |
| WO2003038105A2 (en) * | 2001-11-02 | 2003-05-08 | Danisco A/S | Sequences for the preparation of 5-ketogluconic acid from gluconic acid |
| CN100357446C (zh) * | 2002-09-27 | 2007-12-26 | 帝斯曼知识产权资产管理有限公司 | 维生素c的微生物生产方法 |
| JP4566000B2 (ja) * | 2002-09-27 | 2010-10-20 | ディーエスエム アイピー アセッツ ビー．ブイ． | ビタミンｃを産生する方法 |
| EP1716240B1 (en) * | 2004-01-30 | 2010-06-02 | DSM IP Assets B.V. | Microbial production of vitamin c |
-
2006
- 2006-02-10 BR BRPI0607604-1A patent/BRPI0607604A2/pt not_active Application Discontinuation
- 2006-02-10 US US11/883,477 patent/US20100151516A1/en not_active Abandoned
- 2006-02-10 EP EP06723020A patent/EP1853701A1/en not_active Withdrawn
- 2006-02-10 WO PCT/EP2006/001210 patent/WO2006084715A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US20100151516A1 (en) | 2010-06-17 |
| EP1853701A1 (en) | 2007-11-14 |
| WO2006084715A1 (en) | 2006-08-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
| B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |