BRPI0714563A2 - Infidelidade de transcrição, detecção e usos das mesmas - Google Patents

Infidelidade de transcrição, detecção e usos das mesmas

Info

Publication number
BRPI0714563A2
BRPI0714563A2 BRPI0714563A BRPI0714563A2 BR PI0714563 A2 BRPI0714563 A2 BR PI0714563A2 BR PI0714563 A BRPI0714563 A BR PI0714563A BR PI0714563 A2 BRPI0714563 A2 BR PI0714563A2
Authority
BR
Brazil
Prior art keywords
infidelity
detection
transcription infidelity
design
disease
Prior art date
Application number
Other languages
English (en)
Inventor
Bernard Bihain
Original Assignee
Transmedi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transmedi Sa filed Critical Transmedi Sa
Publication of BRPI0714563A2 publication Critical patent/BRPI0714563A2/pt
Publication of BRPI0714563B1 publication Critical patent/BRPI0714563B1/pt
Publication of BRPI0714563B8 publication Critical patent/BRPI0714563B8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Rheumatology (AREA)
  • Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Glass Compositions (AREA)
  • Pit Excavations, Shoring, Fill Or Stabilisation Of Slopes (AREA)
  • Peptides Or Proteins (AREA)
BRPI0714563A 2006-07-20 2007-07-20 métodos para detectar a pré-disposição à ou estágio de um câncer em um indivíduo mamífero, para triagem, identificação ou otimização de um medicamento anti-câncer, para modificação de um gene de mamífero in vitro e para avaliação da eficácia de um medicamento anti-câncer ou medicamento candidato BRPI0714563B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06291176.3 2006-07-20
EP06291176A EP1887088A1 (en) 2006-07-20 2006-07-20 Transcription infidelity, detection and uses thereof
PCT/EP2007/057541 WO2008009751A2 (en) 2006-07-20 2007-07-20 Transcription infidelity, detection and uses thereof

Publications (3)

Publication Number Publication Date
BRPI0714563A2 true BRPI0714563A2 (pt) 2015-04-14
BRPI0714563B1 BRPI0714563B1 (pt) 2019-07-02
BRPI0714563B8 BRPI0714563B8 (pt) 2021-05-25

Family

ID=37496681

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0714563A BRPI0714563B8 (pt) 2006-07-20 2007-07-20 métodos para detectar a pré-disposição à ou estágio de um câncer em um indivíduo mamífero, para triagem, identificação ou otimização de um medicamento anti-câncer, para modificação de um gene de mamífero in vitro e para avaliação da eficácia de um medicamento anti-câncer ou medicamento candidato

Country Status (18)

Country Link
US (1) US8288091B2 (pt)
EP (3) EP1887088A1 (pt)
JP (1) JP5298013B2 (pt)
KR (1) KR101502179B1 (pt)
AT (1) ATE524565T1 (pt)
AU (1) AU2007275068B2 (pt)
BR (1) BRPI0714563B8 (pt)
CA (1) CA2658305C (pt)
CY (2) CY1112125T1 (pt)
DK (2) DK2046986T3 (pt)
ES (2) ES2373428T3 (pt)
HU (1) HUE028135T2 (pt)
IL (1) IL196600A0 (pt)
PL (2) PL2046986T3 (pt)
PT (2) PT2468885E (pt)
SI (2) SI2468885T1 (pt)
TR (1) TR201112295Y (pt)
WO (1) WO2008009751A2 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2071334A1 (en) 2007-12-14 2009-06-17 Transmedi SA Compositions and methods of detecting TIABS
EP2080812A1 (en) 2008-01-18 2009-07-22 Transmedi SA Compositions and methods of detecting post-stop peptides
EP2995688A1 (en) 2014-09-12 2016-03-16 Genclis Methods of prognosing and treating triple negative breast cancer
EP3387430A4 (en) * 2015-12-11 2019-08-14 Expression Pathology, Inc. SRM / MRM TESTS
JP6899890B2 (ja) * 2016-03-18 2021-07-07 ジェンクリGenclis アレルギーの分子起源
WO2018187216A1 (en) * 2017-04-03 2018-10-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Expression cassettes and methods for detecting transcription errors
EP3700856A4 (en) 2017-10-26 2021-12-15 Ultima Genomics, Inc. METHODS AND SYSTEMS FOR SEQUENCE CALL
WO2020185790A1 (en) 2019-03-10 2020-09-17 Ultima Genomics, Inc. Methods and systems for sequence calling
MX2022001664A (es) 2019-08-09 2022-07-19 Nutcracker Therapeutics Inc Aparato microfluídico y metodos de uso del mismo.
KR102334576B1 (ko) * 2019-08-12 2021-12-07 한국생명공학연구원 융합 단백질 및 이를 포함하는 바이오 이미징용 조성물
US20230343416A1 (en) * 2020-09-10 2023-10-26 Ultima Genomics, Inc. Methods and systems for sequence and variant calling
US20250263453A1 (en) * 2020-11-18 2025-08-21 Industry-University Cooperation Foundation Hanyang University Erica Campus Method for preventing or treating cancer by blocking excessive production of phosphorylated vimentin
EP4162948A1 (en) 2021-10-05 2023-04-12 Genclis Transcription infidelity derived chimeric immunogens and uses thereof
WO2023104904A2 (en) 2021-12-08 2023-06-15 Genclis The sars-cov-2 and variants use two independent cell receptors to replicate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4979330A (en) 1989-10-10 1990-12-25 Rorant Julius W Suction insect trap device
US6120992A (en) 1993-11-04 2000-09-19 Valigene Corporation Use of immobilized mismatch binding protein for detection of mutations and polymorphisms, and allele identification in a diseased human
WO2001040804A2 (en) * 1999-12-03 2001-06-07 Koninklijke Nederlandse Akademie Van Wetenschappen Clearance of aberrant protein in correlation with disease
WO2002077286A1 (en) 2001-02-21 2002-10-03 Gene Check, Inc. Mutation detection using muts and reca
US20060110762A1 (en) * 2004-11-10 2006-05-25 Sanjay Kapil Porcine reproductive and respiratory syndrome virus receptor components and uses thereof

Also Published As

Publication number Publication date
PT2046986E (pt) 2011-12-29
IL196600A0 (en) 2009-11-18
CA2658305A1 (en) 2008-01-24
PT2468885E (pt) 2015-11-26
AU2007275068A1 (en) 2008-01-24
PL2468885T3 (pl) 2016-04-29
DK2046986T3 (da) 2012-01-02
KR101502179B1 (ko) 2015-03-12
EP2046986A2 (en) 2009-04-15
SI2468885T1 (sl) 2016-02-29
WO2008009751A2 (en) 2008-01-24
EP2468885A2 (en) 2012-06-27
EP2468885A3 (en) 2012-08-29
ES2553435T3 (es) 2015-12-09
AU2007275068B2 (en) 2013-06-06
HUE028135T2 (en) 2016-12-28
US8288091B2 (en) 2012-10-16
DK2468885T3 (da) 2016-02-29
EP2046986B1 (en) 2011-09-14
BRPI0714563B1 (pt) 2019-07-02
US20090317386A1 (en) 2009-12-24
EP2468885B1 (en) 2015-08-19
JP2009544284A (ja) 2009-12-17
CY1116939T1 (el) 2017-04-05
ATE524565T1 (de) 2011-09-15
CY1112125T1 (el) 2015-11-04
TR201112295Y (tr) 2018-08-27
PL2046986T3 (pl) 2012-02-29
JP5298013B2 (ja) 2013-09-25
CA2658305C (en) 2017-07-18
HK1128937A1 (en) 2009-11-13
BRPI0714563B8 (pt) 2021-05-25
SI2046986T1 (sl) 2012-05-31
EP1887088A1 (en) 2008-02-13
WO2008009751A3 (en) 2008-07-31
ES2373428T3 (es) 2012-02-03
KR20090052861A (ko) 2009-05-26

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Legal Events

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 02/07/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 02/07/2019, OBSERVADAS AS CONDICOES LEGAIS

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

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B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

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B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2840 DE 10-06-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.