BRPI0807456A2 - Membro de ligação isolado, membros de ligação isolado ou domínio vh e vl, molécula de ácido nucléico isolada, célula hospedeira, método para produzir um membro de ligação isolado, composição farmacêutica, e, uso da composição - Google Patents

Membro de ligação isolado, membros de ligação isolado ou domínio vh e vl, molécula de ácido nucléico isolada, célula hospedeira, método para produzir um membro de ligação isolado, composição farmacêutica, e, uso da composição

Info

Publication number: BRPI0807456A2
Authority: BR; Brazil
Prior art keywords: isolated; connection member; computer use; isolated connection; domain
Prior art date: 2007-02-15

Application number

BRPI0807456-9A2A

Other languages

English (en)

Inventor

Duncan Cochrane

Suzanne Cohen

Claire Louise Dobson

Per-Olof Fredrik Eriksson

Phillip David Monk

Karin Von-Wachenfeldt

Original Assignee

Astrazeneca Ab

Medimmune Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-02-15

Filing date

2008-02-15

Publication date

2015-01-27

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39639279&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0807456(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-02-15 Application filed by Astrazeneca Ab, Medimmune Ltd filed Critical Astrazeneca Ab

2015-01-27 Publication of BRPI0807456A2 publication Critical patent/BRPI0807456A2/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4283—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
- C07K16/4291—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/805—Drug, bio-affecting and body treating compositions involving IgE or IgD
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/862—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving IgE or IgD

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pulmonology (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Microbiology (AREA)
Gastroenterology & Hepatology (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Endocrinology (AREA)
Cell Biology (AREA)
Toxicology (AREA)
Biotechnology (AREA)
Physics & Mathematics (AREA)
Oncology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Communicable Diseases (AREA)
Ophthalmology & Optometry (AREA)
Dermatology (AREA)

BRPI0807456-9A2A 2007-02-15 2008-02-15 Membro de ligação isolado, membros de ligação isolado ou domínio vh e vl, molécula de ácido nucléico isolada, célula hospedeira, método para produzir um membro de ligação isolado, composição farmacêutica, e, uso da composição BRPI0807456A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US90130407P	2007-02-15	2007-02-15
PCT/GB2008/000510 WO2008099178A2 (en)	2007-02-15	2008-02-15	Binding members for ige molecules

Publications (1)

Publication Number	Publication Date
BRPI0807456A2 true BRPI0807456A2 (pt)	2015-01-27

Family

ID=39639279

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0807456-9A2A BRPI0807456A2 (pt)	2007-02-15	2008-02-15	Membro de ligação isolado, membros de ligação isolado ou domínio vh e vl, molécula de ácido nucléico isolada, célula hospedeira, método para produzir um membro de ligação isolado, composição farmacêutica, e, uso da composição

Country Status (19)

Country	Link
US (3)	US8389704B2 (pt)
EP (2)	EP2115007A2 (pt)
JP (1)	JP2010518815A (pt)
KR (1)	KR20100014790A (pt)
CN (1)	CN101675079A (pt)
AR (1)	AR065368A1 (pt)
AU (1)	AU2008216008B2 (pt)
BR (1)	BRPI0807456A2 (pt)
CA (1)	CA2677748A1 (pt)
CL (1)	CL2008000478A1 (pt)
IL (1)	IL200046A0 (pt)
MX (1)	MX2009008410A (pt)
PE (1)	PE20090688A1 (pt)
RU (2)	RU2466140C2 (pt)
SG (1)	SG178767A1 (pt)
TW (1)	TW200844114A (pt)
UY (1)	UY30927A1 (pt)
WO (1)	WO2008099178A2 (pt)
ZA (1)	ZA200905210B (pt)

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AR065368A1 (es) *	2007-02-15	2009-06-03	Astrazeneca Ab	Anticuerpos para moleculas de ige
EP2592094A1 (en) *	2007-02-15	2013-05-15	AstraZeneca AB	Binding members for IgE molecules
CA2712432C (en) *	2008-01-29	2018-09-25	Ablynx N.V.	Methods to stabilize single variable domains
US10017762B2 (en) *	2010-11-24	2018-07-10	The United States Of America, As Represented By The Secretary, Department Of Health & Human Services	Compositions and methods for treating or preventing lupus
WO2014087010A1 (en) *	2012-12-07	2014-06-12	Ablynx N.V.	IMPROVED POLYPEPTIDES DIRECTED AGAINST IgE
TWI691512B (zh)	2015-02-20	2020-04-21	日商橘生藥品工業股份有限公司	Ｆｃ融合高親和性ＩｇＥ受體α鏈
US20180051069A1 (en) *	2015-03-06	2018-02-22	The General Hospital Corporation	Compositions and methods for treating allergic inflammation
KR102038679B1 (ko)	2018-01-12	2019-10-30	(주)지아이이노베이션	프로바이오틱스 및 IgE에 결합능이 있는 폴리펩티드를 포함하는 조성물 및 이의 용도
JP7774293B2 (ja) *	2019-07-24	2025-11-21	国立研究開発法人科学技術振興機構	抗体酵素の革新的製造技術
TWI740647B (zh)	2020-09-15	2021-09-21	宏碁股份有限公司	疾病分類方法及疾病分類裝置
ES2980622T3 (es)	2020-09-19	2024-10-02	Esspen Gmbh	Tomógrafo computarizado y procedimiento para manejar un tomógrafo computarizado
EP4306956A1 (de) *	2022-07-15	2024-01-17	Justus-Liebig-Universität Gießen	Verfahren zum in-vitro nachweis antigen-spezifischer ige verursacht durch eine infektion mit parasiten oder pilzen

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2008
- 2008-01-15 AR ARP080100654A patent/AR065368A1/es unknown
- 2008-02-14 TW TW097105156A patent/TW200844114A/zh unknown
- 2008-02-14 CL CL200800478A patent/CL2008000478A1/es unknown
- 2008-02-14 PE PE2008000321A patent/PE20090688A1/es not_active Application Discontinuation
- 2008-02-15 US US12/527,169 patent/US8389704B2/en active Active
- 2008-02-15 JP JP2009549468A patent/JP2010518815A/ja active Pending
- 2008-02-15 BR BRPI0807456-9A2A patent/BRPI0807456A2/pt not_active IP Right Cessation
- 2008-02-15 WO PCT/GB2008/000510 patent/WO2008099178A2/en not_active Ceased
- 2008-02-15 CN CN200880012211A patent/CN101675079A/zh active Pending
- 2008-02-15 UY UY30927A patent/UY30927A1/es not_active Application Discontinuation
- 2008-02-15 RU RU2009134227/10A patent/RU2466140C2/ru not_active IP Right Cessation
- 2008-02-15 MX MX2009008410A patent/MX2009008410A/es active IP Right Grant
- 2008-02-15 KR KR1020097017009A patent/KR20100014790A/ko not_active Ceased
- 2008-02-15 EP EP08709401A patent/EP2115007A2/en not_active Withdrawn
- 2008-02-15 AU AU2008216008A patent/AU2008216008B2/en not_active Ceased
- 2008-02-15 EP EP13155314.1A patent/EP2620452A1/en not_active Withdrawn
- 2008-02-15 SG SG2012009031A patent/SG178767A1/en unknown
- 2008-02-15 US US12/032,061 patent/US7959917B2/en not_active Expired - Fee Related
- 2008-02-15 CA CA002677748A patent/CA2677748A1/en not_active Abandoned
2009
- 2009-07-23 IL IL200046A patent/IL200046A0/en unknown
- 2009-07-24 ZA ZA200905210A patent/ZA200905210B/xx unknown
2012
- 2012-07-19 RU RU2012130841/10A patent/RU2012130841A/ru not_active Application Discontinuation
- 2012-11-16 US US13/679,080 patent/US20140127212A1/en not_active Abandoned

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Publication number	Publication date
EP2620452A1 (en)	2013-07-31
UY30927A1 (es)	2008-09-30
CN101675079A (zh)	2010-03-17
AU2008216008B2 (en)	2012-07-05
JP2010518815A (ja)	2010-06-03
WO2008099178A2 (en)	2008-08-21
PE20090688A1 (es)	2009-07-15
US8389704B2 (en)	2013-03-05
AU2008216008A1 (en)	2008-08-21
RU2012130841A (ru)	2014-01-27
RU2009134227A (ru)	2011-03-20
CL2008000478A1 (es)	2008-10-17
CA2677748A1 (en)	2008-08-21
TW200844114A (en)	2008-11-16
RU2466140C2 (ru)	2012-11-10
US20090060919A1 (en)	2009-03-05
US20100150904A1 (en)	2010-06-17
KR20100014790A (ko)	2010-02-11
ZA200905210B (en)	2010-03-31
IL200046A0 (en)	2010-04-15
WO2008099178A3 (en)	2008-10-16
SG178767A1 (en)	2012-03-29
US20140127212A1 (en)	2014-05-08
MX2009008410A (es)	2009-08-18
AR065368A1 (es)	2009-06-03
US7959917B2 (en)	2011-06-14
EP2115007A2 (en)	2009-11-11

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2015-12-01	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 7A ANUIDADE.
2016-03-29	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

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